Dose-Response Curve: A Tutorial Study Guide - Nicoladie Tam - E-Book

Dose-Response Curve: A Tutorial Study Guide E-Book

Nicoladie Tam

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Beschreibung

“Dose-Response Curve” is a part of the college-level Neuropsychopharmacology course series textbooks. It is a tutorial written in questions and answers format to describe the pharmacological dose-response curve function and the drug-receptor bindings.


It is a study guide with in-depth explanations. Each section is a modular unit that is self-contained for easy reading. The principles and concepts are introduced systematically so students can learn and retain the materials intuitively.

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Seitenzahl: 28

Veröffentlichungsjahr: 2015

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Dose-Response Curve

A Tutorial Study Guide

 

Nicoladie Tam, Ph. D.

 

Copyright © 2015 by Nicoladie Tam, Ph.D.

 

ISBN 978-1-301-54181-2

 

All rights reserved, no part of this publication may be reproduced in any form, stored in a retrieval system, or transmitted in any form by any means without prior written permission of the author, except in the case of brief quotations in critical review articles.

 

Authored by: Nicoladie Tam, Ph.D.

Published by: Nicoladie Tam, Ph.D.

First Published: August 20, 2013

Revision Date: June 13, 2015

eBook ISBN: 9781301541812

Book statistics: 6,000 words

Keywords: dose-response curve, pharmacology, drug, mental disorder, psychiatric disorder, pharmacotherapy, neuropsychology, neuropharmacology, neuropsychopharmacology, neuroscience, biology, study guide, tutorial

Produced in the United States of America

The printed version of this eBook is also available in PDF format in 32 pages.

 

 

*~*~*~*~*

Preface

“Dose-Response Curve” is a part of the college-level Neuropsychopharmacology course series textbooks. It is a tutorial written in questions and answers format to describe the pharmacological dose-response curve function and the drug-receptor bindings.

It is a study guide with in-depth explanations. Each section is a modular unit that is self-contained for easy reading. The principles and concepts are introduced systematically so students can learn and retain the materials intuitively.

 

*~*~*~*~*

Textbooks by Nicoladie Tam, Ph.D., in the Neuropsychopharmacology course series.

 

Neuropsychopharmacology textbook in one volume:

Neuropsychopharmacology

ISBN 9781311596178

 

Individual chapters of Neuropsychopharmacology textbook series:

Neuropsychopharmacology: An Introduction

ISBN 9781301482733

Scientific Methods

ISBN 9781301898688

Mind-Brain Connection

ISBN 9781301903405

Pharmacology: In Introduction

ISBN 9781301843534

Pharmacokinetics

ISBN 9781301010776

Dose-Response Curve

ISBN 9781301541812

Learning Mechanisms

ISBN 9781301729531

Cognitive Learning

ISBN 9781301966455

Experimental Methods in Neuropsychopharmacology

ISBN 9781301966455

Brain Imaging Techniques

ISBN 9781311863638

Nervous System

ISBN 9781301053025

Neuron

ISBN 9781301119646

Action Potential

ISBN 9781301115372

Synapse

ISBN 9781301374120

Reflex

ISBN 9781301991266

Neurotransmitter

ISBN 9781301268610

Neurotransmitter Pathways

ISBN 9781301696666

Cytoplasmic Release of Neurotransmitters

ISBN 9781311978615

Executive Functions

ISBN 9781301125968

ADHD: Attention Deficit Hyperactivity Disorder

ISBN 9781301318445

Schizophrenia

ISBN 9781301972692

Affective Disorders: Depression, Mania and Bipolar Disorder

ISBN 9781311988416

Anxiety Disorders

ISBN 9781311060419

 

 

Textbooks by Nicoladie Tam, Ph.D., in the Principles of Biology course series.

 

Principles of Biology textbook in one volume:

Principles of Biology: Animal Systems

ISBN 9781301691739

 

Individual chapters of the Principles of Biology textbook series:

Biological System

ISBN 9781301003891

Scientific Methods

ISBN 9781301898688

Biological Principles

ISBN 9781310803666

Origin of Species

ISBN 9781301352456

Nervous System

ISBN 9781301053025

Neuron

ISBN 9781301119646

Action Potential

ISBN 9781301115372

Synapse

ISBN 9781301374120

Reflex

ISBN 9781301991266

Neurotransmitter

ISBN 9781301268610

Sensory System

ISBN 9781301660070

Motor System

ISBN 9781301500895

Endocrine System

ISBN 9781301642939

Reproductive System

ISBN 9781301424078

Circulatory System

ISBN 9781301262410

Respiratory System

ISBN 9781301805389

Immune System

ISBN 9781301452309

Renal System

ISBN 9781301927111

Digestive System

ISBN 9781301317097

 

 

*~*~*~*~*

 

Table of Contents

Cover Page

Preface

Dose-Response Curve

Dosage, Therapeutic and Side Effects

Effective, Toxic dosage and Lethal dosage

Therapeutic index

Potency and Variability of Drug

Competitive and Non-Competitive Binding

About the Author

 

 

*~*~*~*~*

 

1.Dose-Response Curve

Objectives

Understand how to interpret the dose-response curve

Understand the characteristics of a drug revealed by the dose-response curve

Concepts to Learn

Dose and dosage

Therapeutic effects

Side effects

Toxic effects

Effective dosage

ED50

TD50

LD50

Dose-response curves

Shifting dose-response curves to right and/or down

Therapeutic index

Potency

Competitive drug binding

Non-competitive drug binding

Reversibility of drug binding

Irreversibility of drug binding

Agonist

Antagonist

 

 

*~*~*~*~*

 

1.1.Dosage, Therapeutic and Side Effects

Objectives

Understand the difference between dose and dosage

Understand the difference between therapeutic effects and side effects

Understand the difference between toxic effects and lethal effects

Concepts to Learn

Dose and dosage

Therapeutic effects and side effects

Effective, toxic and lethal effects