Nanomedicine - Overview of a new science E-Book

casella marco

• Herausgeber: Marco Casella
• Kategorie: Wissenschaft und neue Technologien
• Sprache: Englisch

Veröffentlichungsjahr: 2015

Beschreibung

This book wants to provide an overview of nanomedicine. The book particularly deals with the nanomedical applications (drug delivery, LOCs and bioMEMS) and the positive and negative effects of nanotechnologies on human health.

Leseprobe

Marco Casella

NANOMEDICINE - OVERVIEW OF A NEW SCIENCE

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Table of contents

Introduction

Nanotechnologies and biomedical applications

The drug delivery

The lab-on-a-chips and bioMEMS

Pharmaceutical nanotechnologies

Bionanotechnologies: positive aspects and risks for health

Pharmacokinetics of nanoparticles

The toxicity of the nanoparticles

Risk assessment of the NPs

Introduction

Nanomedicine is by now a big industry.

The possible applications go from the clinical use of nanomaterials, to the formulation of new systems for the drug administration, to nanotechnological biosensors and to the possible use of molecular nanotechnology in the middle period. The research has had for some years the objective to realize laboratories to develop the technologies in the bio-medical field like the drug delivery and the early diagnosis of tumours. They will have huge potentials in the design of lab-on-a-chip (LOCs) for the pharmacological treatment of tumors thanks to their interdisciplinary nature between life sciences (medicine, biology and pharmacy) and exact sciences (physics and chemistry).

In particular, these studies will include two development phases.

The first one concerns the drug delivery, in terms of study of the structural properties, of dynamics at molecular level of some classes of nanostructured systems of interest, of study of the targeting and of release speed of the drug in vitro by the vector in relation to the functionalization of surfaces and to the 3D structure created through microfabrication and nanofabrication.

The second development phase concerns the choice of the devices to design and to realize for a better early diagnosis of tumors, like LOCs and bioMEMS.

The book is divided into two main parts.

In the first part, a general overview will be given of nanomedical applications with reference to the drug delivery, in all its forms and structures, LOCs and bioMEMS. A paragraph will be dedicated to pharmaceutical nanotechnologies. Eventually, the positive aspects and the risks for health of nanotechnologies will be explained.

In the second part of the book, the aspects related to the pharmacokinetics of nanoparticles and their toxicity degree in man will be analyzed. Eventually, the risks that nanoparticles can have on human health will be assessed.