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Beschreibung

Textbook of Advanced Dermatology: Pearls for Academia and Skin Clinics is an essential reference for practicing dermatologists in hospitals and clinics. The book aims to provide interesting tips that cannot be found in traditional dermatology handbooks. The contributors include top minds in dermatology and related fields such as Joe Niamtu, Samuel Lam, and Steven Feldman. Topics in the book include novel, original formulations for topical compounds, ways to improve patient adherence to prescriptions, business tips, novelties in skin surgery, and solutions for preventing patient complaints and legal suits. The book also highlights the author’s personal experiences gained over many years in improving everyday clinical dermatology practice.

The book is divided into 5 sections each representing ‘pearls’ of advice: Teaching Pearls, Medical Pearls, Publication Pearls, Procedural Pearls, and Business Pearls, encompassing all of the broad realm of dermatology.

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Seitenzahl: 210

Veröffentlichungsjahr: 2024

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Table of Contents
BENTHAM SCIENCE PUBLISHERS LTD.
End User License Agreement (for non-institutional, personal use)
Usage Rules:
Disclaimer:
Limitation of Liability:
General:
PREFACE
List of Contributors
DEDICATION
Introduction
Teaching Pearls
Interesting Ways to Encourage Trainees for Proper History Taking and Physical Examination
REFERENCES
Two Big Teaching Mistakes that Young Assistant Professors/Consultants May Make
References
Unknown Slides: Very Useful Teaching Materials
Medical Pearls
Practical Ways to Improve Patient Adherence
References
Moisturizer Pearls
References
How to Make an Oily Calamine Compound Which Does Not Dry the Skin?
References
How to Make Strong Topical Anti-Itch Compounds?
References
Topical Steroids and Steroid Vehicles: Some Pearls
References
Steroids: Some Pearls
References
Steroid Comparison Table
REFERENCES
Pulse Steroid Therapy
References
Intradermal Triamcinolone Injection
Reference
Increasing the Efficacy of Intravenous N-acetylcysteine
References
Postherpetic Neuralgia: Pearls
References
An Important Point in Intravenous Acyclovir Administration
References
Genital Warts: Pearls
REFERENCES
Upton's Paste: An Extremely Potent Compound for Resistant Warts, Callouses and Corns
Reference
Good Keratolytics for Non-irritated Thick Skin, E.g., Lichen Simplex Chronicus and Keratosis Pilaris
Reference
Anti-histamines Pearls
References
Acne Management: Pearls
References
Which Topicals are Appropriate for Acne Patients with Dry Skin?
Reference
Melasma Pearls
References
How to Make a Strong Anti-Acne and Anti-Pigment Agent?
References
How to Treat Peri-Orbital Hypermelanosis and Melasma in Sensitive Skin?
REFERENCES
Doxycycline or Azithromycin for Perifollicular Elastolysis?
References
Excessive Skin Oiliness: Tips
References
Enlarged Pores
Reference
Facial Erythema
References
What is an Excellent Anti-Redness Emollient for Ichthyosiform Erythroderma?
References
Pemphigus Pearls
References
Pathergy Testing for Diagnosing Behcet’s Disease
Reference
Mild-to-Moderate Psoriasis Tips
References
Severe Psoriasis: Pearls
References
Seborrheic Dermatitis Tips
References
Wound Vac and Hyperbaric Oxygen for Wound Healing
References
Some Tips on Head Lice Management
References
Cutaneous Leishmaniasis Pearls
References
Alopecia Areata: Some Tips
References
The Benefits of Potassium Permanganate
References
Strengthening the Immune Response
References
Macular Amyloidosis Pearls
References
Mycosis Fungoides Pearls
References
The Pro-oxidant Activity of Anti-oxidants and its Practical Implications
References
How to Prevent the Growth of Neurofibromas?
References
How to Expedite Depigmentation Therapy in Vitiligo?
References
The Problem in Diagnosing Early Vitiligo
References
Vitiligo Pearls
References
Tips to Prevent Hair Damage
References
Androgenetic Hair Loss: Some Important Management Tips
References
Telogen Effluvium: Tips
References
Frontal Fibrosing Alopecia/lichen Planopilaris: Some Pearls
References
Methotrexate Pearls
References
Intravenous Immunoglobulin Pearls
References
A Simple, Limited Patch Testing
References
Wet Wrap
References
Management of Varicose Veins
References
Improving Scar Formation: Pearls
References
Miscellaneous Medical Pearls
References
Publication Pearls
Publication Pearls
Textbook of Advanced
Dermatology: Pearls for
Academia and Skin Clinics
(Part 1)
Edited by
Mohammad Reza Namazi
Shiraz University of Medical Sciences and
Dr. Namazi Skin and Hair Clinic, Shiraz, Iran

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PREFACE

"My intentions are to spread knowledge; I consider this the most important happiness."

Biruni, a Persian encyclopedic scientist

“Our writings will remain, while we will go. Nothing will remain in the world from us except our writings.”

Ferdowsi, a Persian giant poet

"Do not coil on the treasure of science like a snake and deprive science-seekers from acquiring it."

Ali-ibn-Abitaleb, an Arab leader

During my 20-year dermatology practice, including my residency period, I have frequently encountered important clinical challenges that could not be solved by referring to major dermatology textbooks, making me search dermatology papers and the less well-known books to solve these problems. Also, during the past two decades, I have been practicing both medical and procedural dermatology as well as conducting research and writing papers; therefore, I have gained a lot of experience which is not mentioned anywhere. Not to mention my experience in teaching as a university academic staff and in business as a founder and director of my private dermatology clinic.

I thought it would be a big pity not to share the interesting practical points I learned and also my laboriously achieved experience with my colleagues and future dermatologists, believing that any person should write at least one book during his lifetime to share his unique experience with his/her fellow human beings. Actually, this was the motivation to start writing this book. Later on, I became interested in encouraging the collaboration of other colleagues, some being the world leaders in their specific fields, to strengthen this book. I would like to extend my deep gratitude to these dear colleagues who have greatly honored me with their marvelous contributions.

The present book is composed of 5 sections: Teaching Pearls, Medical Pearls, Procedural Pearls, Publication Pearls, and Business Pearls, therefore, encompassing the broad realm of dermatology and filling the large gap in the major dermatology textbooks. Importantly, this book does not aim to provide detailed information on each topic, rather it aims to provide interesting tips which cannot be found or can hardly be found elsewhere. Therefore, as an advanced dermatology textbook, much important essential information that can easily be obtained from other publications is not included in this book.

I would like to thank all my dear colleagues who have kindly referred surgical patients to me, especially Drs. Ali Mohammad Namiyan, Amir Kalafi, Mahsa Naseri, Masoud Koraee, Ahmad Moradi, Arash Abtahiyan, Yasaam Khosravi, Khalil Hamedpour and other colleagues whom I may not remember.

I would also like to thank my assistants, Mr. Mohammad Khanchefalak and Ms. Bahar Bayat, for their help in taking photos and Prof. Nasrin Shokrpour for editing some parts of this book.

This preface cannot be concluded without sincerely thanking Bentham’s publishing staff, especially Miss Humaira Hashmi, Ms. Simra Nasir and Ms. Ambreen Irshad, for their help in making the dream of this book a reality.

"This well-arranged composition will remain for years, When every atom of our dust is dispersed.

The intention of this design was that it should survive

Because I perceive no stability in my existence…”

This poem is from Saadi Shirazi, a great Persian poet (translated by Edward Rehatsek into English).

Mohammad Reza Namazi Shiraz University of Medical Sciences and Dr. Namazi Skin and Hair Clinic, Shiraz, Iran

List of Contributors

Mohammad Reza NamaziShiraz University of Medical Sciences and Dr. Namazi Skin and Hair Clinic, Shiraz, IranMegan MukengeCenter for Dermatology Research, Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USAChristina KontziasCenter for Dermatology Research, Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USASteven R. FeldmanDepartment of Social Sciences & Health Policy, Wake Forest School of Medicine, Winston-Salem, North Carolina, USAAlyssa CurcioCenter for Dermatology Research, Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA

DEDICATION

To Drs. Uranus Dasmeh, Aliakbar Mohammadi, Vahid Dastgerdi, plastic surgeons in Shiraz, Iran and Dr. Mohsen Alirezai, dermatologist and plastic surgeon in Montpellier, France, for responding to my consultations and queries; Dr. Manouchr Sodaifi, founder of the Dermatology Department of Shiraz University of Medical Sciences, for his amazing interest in teaching; and Dr. Behrooz Kasraee for his help.

To my dear wife Masoumeh, who got headaches on weekends from the constant sound of typing this book from dawn to dusk, and our beloved flowers Sahand and Anahid.

To the memory of Prof. Karim Vessal, the Father of Iran's Modern Medical Editing:

“Near, far, wherever you are, I believe that the heart does go on…

You are safe in our hearts, and our hearts will go on and on…"

Introduction

Mohammad Reza Namazi1,*
1 Shiraz University of Medical Sciences and Dr. Namazi Skin and Hair Clinic, Shiraz, Iran
*Corresponding author Mohammad Reza Namazi: Shiraz University of Medical Sciences and Dr. Namazi Skin and Hair Clinic, Shiraz, Iran; E-mail: [email protected]

Dermatology seems to be originated from internal medicine. The older generation of dermatologists was mainly involved in treating skin diseases. However, this field has progressed tremendously during the past decades, advancing its procedural part to include many surgical operations that were traditionally believed to lie within the realm of plastic surgery.

On the other hand, the progress in laser technology has dramatically advanced the borders of dermatology. A few decades ago, thinking about the use of laser in dermatology was just like science fiction.

Since dermatology is a lucrative field, especially its aesthetic and procedural parts, other physicians, such as general practitioners and even some specialists, have been lured to undertake many non-invasive or minimally invasive procedures that dermatologists believe to belong to their field. This has led to a fierce competition, and the winner of this competition, being cut-throat in some countries, is perhaps the person who not only masters the aforementioned procedures but also knows the business acumen. Unfortunately, business issues, while important, are not taught in the residency period, and there are many expert dermatologists who end up working in clinics belonging to businessmen because they do not know the business acumen.

In this book, besides the purely academic parts of dermatology, i.e., teaching and research, other sections of this wide discipline, i.e., medical, aesthetic and procedural parts, are also covered, and a separate section is also devoted to the business tips.

In the medical section, many compounding formulations of topical compounds are provided. These are mainly based on the author’s experience in the prescription of topical compounds. The prescription of topical compounds is done for several reasons. Firstly, the available commercial products may not contain all the ingre-

dients effective against different pathophysiologic aspects of a condition. This may be due to the novelty of a compounding formula or the fact that compounding on an industrial scale is so difficult compared to that on a small scale performed in a local pharmacy. Secondly, the commercial products may not have the required ingredients at the concentrations a dermatologist prefers. Thirdly, to have an adequate shelf-life, preservatives are added to commercial products, which can negatively affect the skin, especially sensitive skin. Finally, there are some patients who would rather use a prescription compound than a commercial product because they are fed up or disappointed with the latter, or they think prescription compounds are stronger. Therefore, knowing compounding formulations is a must for every competent dermatologist and is usually a distinguishing feature from a general practitioner.

I hope the readers find the tips provided in this textbook useful.

Teaching Pearls

Interesting Ways to Encourage Trainees for Proper History Taking and Physical Examination

Mohammad Reza Namazi1,*
1 Shiraz University of Medical Sciences and Dr. Namazi Skin and Hair Clinic, Shiraz, Iran
*Corresponding author Mohammad Reza Namazi: Shiraz University of Medical Sciences and Dr. Namazi Skin and Hair Clinic, Shiraz, Iran; E-mail: [email protected]

Developing the trainees’ observation skills and encouraging them to spend adequate time on meticulous history taking and physical examination are not done easily. Two interesting tips to achieve these goals are presented:

-Tell the story of Al-Bakri, the great traveler of mind:

Al-Bakri was born in Spain (1040-1094 CE). He received travelers and merchants in his home and interpreted their stories into his “Book of Highways and Kingdoms”. He made accurate references to the geography, culture, religion and trade of Europe, North Africa and the Arabian Peninsula, all this without ever traveling to these distant lands himself! [1] The crater Al-Bakri on the Moon is named after him [2]. Al-Bakri is perhaps the greatest history taker in human history.

A giant semblance of Al-Bakri was displayed at Expo 2020 in Dubai (Fig. 1).

- The Sherlock Holmes series and stories can serve as excellent astuteness inspirers for medical trainees. Sherlock Holmes is a fictional supersleuth who greatly stresses on keen observation, meticulous inspection and heeding details and apparent trifles, which are especially related to dermatological practice. It has been appropriately said that a dermatologist should be a proficient detective possessing the powers of observation and deduction when facing contact dermatitis [3]. In “The Adventure of the Blanched Soldier”, Holmes states that he has the habit of sitting with his back to the window while seating his clients in the opposite chair where the light falls fully upon them. Dermatological practice in the gaslight era was exactly the same. Additionally, the dermatologist must have enough exposure of the skin, not trusting the patient’s assurance that lesions are or are not present in an area or that they are similar or dissimilar to the ones that

have been shown. “There is nothing like first-hand evidence,” says Holmes in “A Study in Scarlet”. He disapproves of theorising on inadequate data in “The Valley of Fear”. The dermatologic examination needs the highest alertness. In “The Hound of the Baskervilles”, Holmes states that “The world is full of obvious things that nobody by any chance ever observes” [4].

Fig. (l)) Al-Bakri's giant semblance in Expo 2020, Dubai.

William Bennett Bean, a professor of medicine and the Chair of Internal Medicine at the College of Medicine, University of Iowa, wrote that novices in medicine should master Sherlock Holmes [5]. Ira Martin Grais, a cardiologist at Northwestern University Feinberg School of Medicine in Chicago, mentioned that during the 5 decades of teaching in medical schools, he had made the reading of certain Sherlock Holmes stories mandatory for the trainees [6].

In 1885, Dr. Arthur Conan Doyle, a young physician, created Sherlock Holmes, modeled upon a Scottish lecturer and surgeon at the University of Edinburgh, Dr. Joseph Bell, who stressed the importance of careful observation in making a diagnosis. To demonstrate this, he often chose a stranger and deduced his job and recent activities by observing him. He would surprise his students with his intuitive powers and sharp observation skills and stressed the significance of developing students’ observant faculties [3].

Sherlock Holmes stories are very influential and interesting, especially for young people. A paper published in the Journal of Dermatology and Surgical Oncology in 1979 [4], i.e., 93 years after the creation of Sherlock Holmes, mentioned that “Hundreds of letters are still addressed to him [at 221B Baker Street, London] each year, asking for help or advice!”

The Sherlock Holmes Society of London, founded in 1951, publishes Sherlock Holmes Journal twice a year and has erected a big statue of him in London (Fig. 2). The Sherlock Holmes Museum (Fig. 3) was opened in 1990 in Baker Street and features some items from several different adaptations of Sherlock Holmes. A PubMed search for papers having “Sherlock Holmes” in their titles/abstracts revealed 182 results at the time of writing this text (10 March 2023), including some papers published in 2023.

Fig. (2)) Sherlock Holmes’ Colossus in London. Fig. (3)) Sherlock Holm’s Museum in London. Holmes asserted his habit of sitting with his back to the window while seating his clients in the opposite chair with the light falling fully on them.

REFERENCES

[1]Lévi-Provençal E, Abū U. Encyclopaedia of Islam (2nd.) 2nd.1960; 1: 155-7.[2]Gazetteer of Planetary Nomenclature. https://planetarynames.wr.usgs.gov/Feature/145. Accessed: 12/9/2022.[3]Klauder JV. Sherlock Holmes as a dermatologist, with remarks on the life of Dr. Joseph Bell and the Sherlockian method of teaching. AMA Arch Derm Syphilol. 1953 Oct; 68(4): 363-77.[4]Dirckx JH. Medicine and literature: Sherlock Holmes and the art of dermatologic diagnosis. J Dermatol Surg Oncol. 1979 Mar; 5(3): 191-6 4.[5]Bean WB. The private life of Sherlock Holmes by Vincent Starrett [book review]. Arch Intern Med 1962; 110(6): 926-7.[6]Grais IM. False scents, false sense, and false cents: why physicians should read Sherlock Holmes. Tex Heart Inst J. 2012; 39(3): 319-21.

Two Big Teaching Mistakes that Young Assistant Professors/Consultants May Make

Mohammad Reza Namazi1,*
1 Shiraz University of Medical Sciences and Dr. Namazi Skin and Hair Clinic, Shiraz, Iran
*Corresponding author Mohammad Reza Namazi: Shiraz University of Medical Sciences and Dr. Namazi Skin and Hair Clinic, Shiraz, Iran; E-mail: [email protected]

Herein, I tell the story of the two mistakes I made while I was a young Assistant Professor in order to help my colleagues promote their teaching methods.

At the start of my career at the university as an Assistant Professor, I thought that I should encourage the trainees to study more by asking them tough questions that could not be answered by them and then reprimanding them for not knowing the answer. I thought the pain inflicted by my criticism would stimulate them to study more and gain more knowledge. Though this may be true, it was not a good approach as it was distressing for them, making them not like me and attend my classes and clinics with alacrity. Moreover, in many situations, I asked them unimportant, difficult questions, e.g., the percentages mentioned in textbooks of various manifestations of a disease, to achieve my goal, which was a waste of time, of course.

While I was a fellow in the prestigious dermatology department of Wake-Forest University, USA, I learned an interesting, completely opposite approach from Prof. Omar Sangueza, a famous dermatopathologist and the Editor-in-Chief of the American Journal of Dermatopathology. Unlike me, he asked the residents only important questions and gave energizing, positive feedback to those who answered correctly by saying: “You are completely right [with a high intonation]. The diagnosis is…”

B.F. Skinner, one of the most influential psychologists of the 20th century, has shown that an animal who is rewarded for a wanted behavior learns that behavior more rapidly than an animal who is punished for an unwanted behavior. This can be applicable to teaching humans. Criticisms cause resentment and even hatred. Instead, be positive and encourage people [1].

The second mistake I used to make was to dominate my teaching at dermatology rounds with basic science materials, including very complex subjects, because I loved basic sciences. I asked the residents and even the medical students difficult questions regarding the pathophysiology of diseases and cellular and molecular medicine. Most of them disliked these topics; they were mainly interested in clinical and practical subjects. With time, I learned to dominate my discussions with practical materials, mentioning only very important basic science subjects having practical implications. The following sentences from the book “How to Win Friends and Influence People”, the seventh most influential book in American history written by Dale Carnegie (Fig. 1), deserve careful consideration:

Fig. (1)) Dale Carnegie, the American writer whose book “How to Win Friends and Influence People” had sold five million copies in 31 languages by the time of his death.

“I often went fishing up in Maine during the summer. Personally, I am very fond of strawberries and cream, but I have found that, for some strange reason, fish prefer worms. So when I went fishing, I didn’t think about what I wanted. I thought about what they wanted. I didn’t bait the hook with strawberries and cream. Rather, I dangled a worm or a grasshopper in front of the fish and said: “Wouldn’t you like to have that?” Why not use the same common sense when fishing for people?

Why talk about what we want? That is childish. Absurd. Of course, you are interested in what you want. You are eternally interested in it. But no one else is. The rest of us are just like you: we are interested in what we want.” [2].

References

[1]Carnegie D. How to Win Friends and Influence People? (9th ed.) 9th ed.Jafari R, Ghaemi P. 200924.[2]Carnegie D. How to Win Friends and Influence People? (Revised edition.) Revised edition.198146.

Unknown Slides: Very Useful Teaching Materials

Mohammad Reza Namazi1,*
1 Shiraz University of Medical Sciences and Dr. Namazi Skin and Hair Clinic, Shiraz, Iran
*Corresponding author Mohammad Reza Namazi: Shiraz University of Medical Sciences and Dr. Namazi Skin and Hair Clinic, Shiraz, Iran; E-mail: [email protected]

Knowing impactful teaching methods can dramatically enhance your teaching capability.

A remarkable teaching method I noticed at the Department of Dermatology at Wake Forest University, USA, was the use of unknown slides. Several slides with no diagnoses were placed in a room near a microscope at the beginning of each week. Residents had the chance to see them and guess the diagnoses prior to discussing the correct diagnoses by the pathologists at the end of the week.

Medical Pearls

Practical Ways to Improve Patient Adherence

Megan Mukenge1,Christina Kontzias1,Steven R. Feldman1,*
1 Center for Dermatology Research, Department of Dermatology, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA
*Corresponding author Steven R. Feldman: Department of Social Sciences & Health Policy, Wake Forest School of Medicine, Winston- Salem, North Carolina, USA; E-mail: [email protected]

Patient adherence involves collaboration between the patients and their providers. Poor adherence can negatively impact clinical outcomes and increase frustration among patients. Provided are pearls for promoting patient adherence: