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This book offers in-depth reviews of different techniques and novel approaches of using blockchain and artificial intelligence in smart healthcare services. The volume brings 14 reviews and research articles written by academicians, researchers and industry professionals to give readers a current perspective of smart healthcare solutions for medical and public health services.

The book starts with examples of how blockchain can be applied in healthcare services such as the care of osteoporosis patients and security. Several chapters review AI models for disease detection including breast cancer, colon cancer and anemia. The authors have included model design and parameters for the benefit of professionals who want to implement specific algorithms. Furthermore, the book also includes chapters on IoT frameworks for smart healthcare systems, giving readers a primer on how to utilize the technology in this sector. Additional use cases for machine learning for gesture learning. COVID-19 management, and sentiment analysis.

Readership
Academic, professional, and students affiliated institutions involved in digital transformation in the healthcare sector.

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Table of Contents
BENTHAM SCIENCE PUBLISHERS LTD.
End User License Agreement (for non-institutional, personal use)
Usage Rules:
Disclaimer:
Limitation of Liability:
General:
PREFACE
List of Contributors
Blockchain Associated Machine Learning Approach for Earlier Prognosis and Preclusion of Osteoporosis in Elderly
Abstract
Introduction
Related Studies
Methodology in the Proposed Work
Principal Component Analysis (PCA)
Weighted kNN
Proposed PCA-wkNN
Dataset Description
Implementation and Results
Conclusion and Future Scope
REFERENCES
Online Detection of Malnutrition Induced Anemia from Nail Color using Machine Learning Algorithms
Abstract
Introduction
Related Studies
OBJECTIVES AND NOVELTY OF THE PROPOSED WORK
Scientific Significance
Gaps to be Covered through Proposed Work
Technical Solution
Methodology
Results and Discussion
Comparison of the System Taken up for Development
Principle or Operation
Conclusion and Future Scope
REFERENCES
Artificial Intelligence and Bioinformatics Promise Smart and Secure Healthcare: A COVID-19 Perspective
Abstract
Introduction
Artificial Intelligence and Bioinformatics
Role of Bioinformatics in Healthcare
Role of Artificial Intelligence in Healthcare
Artificial Intelligence, Healthcare, and Bioinformatics: A Win-Win Combination
Biology of SARS-COV2
BATS and SARS-COV-2
Bioinformatics Study of SARS-COV-2
Artificial intelligence and bioinformatics promise smart and secure healthcare amidst Covid-19 outbreak
In silico comparative analysis of genome and proteome of Sars-Cov2 with the bat, virome promises gateway for health-care
Selection of Target Organisms
Global and Local Pairwise Alignment of the Genomes of SARS-CoV2 and the Study Species from Bat Virome
Phylogenetic Tree Analysis
Global and Local Pairwise Alignment of the RNA-dependent RNA Polymerase Sequences of SARS-CoV2 and the Study Species from bat Virome
Multiple Sequence Alignment of RNA-dependent RNA Polymerase Sequences of SARS-CoV2 and the viral Study Species from Bat Virome
Phylogenetic Analysis
Conclusion and Future Scope
REFERENCES
Detection of Breast Cancer Using Context-Aware Capsule Neural Network
Abstract
Introduction
Approaches for breast cancer detection
2D Mammograms
3D Mammograms or Computed Tomography (CT) Scans
Ultrasound
Magnetic Resonance Imaging (MRI)
Positron Imaging Test (PET) Scan
Thermography
Histopathology
Deep Learning-based Method for Breast Cancer Detection
TRADITIONAL MACHINE LEARNING MODELS IN BREAST CANCER DETECTION USING MAMMOGRAMS
ARTIFICIAL NEURAL NETWORKS IN BREAST CANCER DETECTION USING MAMMOGRAMS
CONVOLUTIONAL NEURAL NETWORKS (CNN) IN BREAST CANCER DETECTION USING MAMMOGRAMS
Transfer learning (TL) based CNN
Residual learning (RL) based CNN
Proposed Methodology
Blockchain
Result Analysis
Comparison of Capsule Neural Network-based and Convolutional Neural Network-based Breast Cancer Detection
CONCLUSION AND FUTURE SCOPE
REFERENCES
Enhancement of Breast Cancer Screening through Texture and Deep Feature Fusion Model using MLO and CC View Mammograms
Abstract
Introduction
Related study
Materials and methods
Results and Discussions
Conclusion and Future Scope
references
Artificial Intelligence Assisted Colonoscopy in Diagnosis of Colorectal Cancer
Abstract
Introduction
Overview of AI in Diagnostic Medicine
Embracing Artificial Intelligence in Oncology
Role of AI in the Detection of Cancers as Evidenced by Current Literature
Role of AI in Oncological Treatment
Influence of AI in the Prognosis of Cancers
The Advent of AI in Diagnostic Colonoscopy
Challenges to AI Colonoscopy Implementation and its Limitations
Potential Role of Integrating AI and BlockChain in Diagnostic Imaging
Conclusion
REFERENCES
Developing a Smart Device for the Manufacture of Healthcare Products for Patients Using the Internet of Things
Abstract
Introduction
IoT Capabilities of Devices
Blockchain Technology in Work
Blockchain Proposed Methodology
1. Data Logging and Verification
2. Transparency and Real-time Tracking
3. Smart Contracts for Automated Processes
4. Supplier Verification and Compliance
5. Immutable Records for Auditing
What is the role of security/privacy in this process?
1. Data Encryption
2. Secure Authentication
3. End-to-End Encryption
4. Privacy by Design
5. Data Minimization
6. Secure Storage
7. Regular Software Updates
8. User Consent and Control
10. Regular Security Audits
11. Compliance with Regulations
IoT Architectures
Smart Healthcare Applications
Devices for Monitoring Healthcare
Remote Patient Supervision
Glucose Monitoring
Heart-rate Monitoring
Hand Hygiene Monitoring
The Importance of Security for IoT in Healthcare
Smart Healthcare Classifications
Smart Healthcare Needs, Characteristics, and Components
IoT for Smart Healthcare
Intelligent Healthcare: Recent Trends in the Industry and New Products
Challenges, Vulnerabilities, and Opportunities of Smart Healthcare
The Nano Smart Healthcare
Conclusion and Future Scope
REFERENCES
Blockchain Security in Healthcare
Abstract
Introduction
Private blockchain network
Blockchain security in healthcare
Encryption
Audit Trails and Logging
Data Minimization and Redaction
Consent Management
Data Segmentation
Regular Security Audits and Penetration Testing
Vendor Security Assessments
Training and Awareness
Incident Response Plan
Data Backups and Recovery
Blockchain technology
Internet of Medical Things (IOMT) in Blockchain
How Blockchain Works
Types of Blockchains
Enhanced quality control of patient records - proposed work
POLICE BRUTALITY IS AN INFRINGEMENT OF HUMAN RIGHTS IN INDIA
Here are Some Alternative Section Title Suggestions that You Could use Instead
Registration Contract with Patients
Advantages of blockchain technology
Challenges Faced by Blockchain Technology in the Healthcare Industry
EHR-entity Relationship
Blockchain Technology in Healthcare Data Management
Conclusion, Limitations, and Future Scope
REFERENCES
Enhancing the Communication of Speech-Impaired People Using Embedded Vision-based Gesture Recognition through Deep Learning
Abstract
Introduction
Related Studies
Materials and Methods
Dataset
Pre-Processing
Image Feature Extraction
FAST and BRIEF
Oriented Fast and Rotated Brief (ORB)
Speeded-Up and Robust Feature
KAZE
Dimensionality Reduction Using PCA
Transfer Learning Using Pre-trained Models
Pre-trained model as a feature extractor
Methodology I
Methodology II
Methodology III
Evaluation Metrics
Hardware Implementation
Results and Discussions
Methodology I
Methodology II
Methodology III
Conclusion and Future Scope
REFERENCES
Advancing Data Science: A New Ray of Hope to Mental Health Care
Abstract
Introduction: AI and Mental Healthcare
Related Studies - The Structure of Care
Process of Care
The Outcome of Care
THE USE OF AI FOR PERSONALIZED TREATMENT
Ethical and legal aspects of AI in Psychiatry
Ethical and Legal concerns in Psychiatry
Ethical Issues for AI in Psychiatry
Types of Computation Models
Blockchain technology in mental healthcare
Evidence of use of Blockchain Technology (BcT) in Psychiatry
Can blockchain technology be of any use in Psychiatry?
Conclusion, challenges, and future scope
Acknowledgments
REFERENCES
Machine Learning-Based Methods for Pneumonia Disease Detection in Health Industry
Abstract
Introduction
Problem Outline
Anatomy of Human Lung
Lung Disease Types
Classification of Pneumonia
Symptoms of Pneumonia
Stages of Pneumonia
Diagnosis of Pneumonia
Pneumonia Risk Factors
Machine learning
Machine Learning Types
Healthcare support system
Motivation for the Work
Machine Learning Methods for Pneumonia Diagnosis
Conclusion and future scope
REFERENCES
Framework towards Smart Healthcare Tourism Based on the Internet of Medical Things (IoMT)
Abstract
Introduction
COVID-19 disease symptoms and preventive measures
Health Tourism in India
Internet of Things
Healthcare Architecture in IoT
Significance in COVID Environment
Proposed framework
Blockchain IoT
Discussion
Conclusion and Future Scope
REFERENCES
Unmasking the Sentiments of People Towards Pandemic: Twitter Sentiment Analysis in Real-Time
Abstract
Introduction
Related Studies
Proposed work - data and methodology
Sentimental Analysis
Discussion and findings
Conclusion and Future Scope
REFERENCES
Application of Industry 4.0: AI and IoT to Improve Supply Chain Performance
Abstract
Introduction
Related Studies
Advantages of Artificial Intelligence
Conclusion and Future Scope
REFERENCES
Advances in Computing
Communications and
Informatics
(Volume 7)
Exploration of Artificial
Intelligence and Blockchain
Technology in Smart and Secure
Healthcare
Edited by
Arvind K. Sharma
Shoolini University
Solan, Himachal Pradesh
India
Dalip Kamboj
Maharishi Markandeshwar (Deemed to be University)
Mullana-Ambala, Haryana
India
Savita Wadhawan
Maharishi Markandeshwar (Deemed to be University)
Mullana-Ambala, Haryana
India
Gousia Habib
Department of Computer Science
National Institute of Technology Srinagar
Srinagar
India
Samiya Khan
School of Computing and Mathematical Sciences
University of Greenwich
London, UK
&
Valentina Emilia Balas
Department of Automation and Applied Informatics
Aurel Vlaicu University
Arad, Romania

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PREFACE

From the last decade onward, a considerable amount of research and developments in technology have taken place especially in the healthcare industry, with the involvement of technologies like Artificial Intelligence (AI), Machine Learning (ML), Deep Learning, Blockchain, Communication Systems, Internet of Things, Multisensory Systems, etc. The purpose is only to make smart and secure healthcare possible. Machine Learning techniques and algorithms are required to give a boost to the aim of smart healthcare. Hence, to fulfill the vision of smart healthcare, the tools and applications based on Artificial Intelligence and Machine Learning are becoming extremely popular for producing more accuracy (in terms of values) in predicting results (without being explicitly programmed) in the healthcare industry. However, Artificial Intelligence-based algorithms are quite helpful for the transformation of physiological data into clinical information of real values, but for processing such big data from a set of medical images and identifying or extracting characteristic patterns of health function, then translating these patterns into clinical information definitely requires an adequate knowledge base of physiology, advanced digital signal processing capabilities, and machine learning. The domain of Artificial Intelligence can be taken into three main groups viz. Artificial Slight Intellect, Artificial Overall Intelligence, and Artificial Super Intelligence, and undoubtedly all these groups work in an absolute manner in the presence of fundamental or advanced Machine Learning techniques. There are a number of categories existing concerning the AI/ML algorithms used for fulfilling the objective of smart healthcare such as supervised (regression, decision-tree, classification) and unsupervised (clustering, association analysis, hidden Markov model, etc.). Although the preparation of intelligent algorithms or systems based on AI/ML combined with novel wearable portable devices (especially sensors etc.) offers unprecedented possibilities and opportunities for remote patient monitoring, traditional sharing schemes cannot guarantee the security and immutability of data. Machine Learning along with Artificial Intelligence is quite helpful towards the research and development in health care, but still lacking somewhat especially in security and privacy related to healthcare information of all categories i.e. the dream of smart healthcare is far behind. So to make the dream of smart healthcare come true, the emerging Blockchain technology is spreading its feet in the healthcare industry having revolutionized results. The Blockchain is helping in numerous perspectives in health care such that for managing the security, the integrity of data i.e. electronic health records (EHRs), electronic medical records (EMRs); preserving immutability of data, tracking the origin, spreading of data, the authenticity of data, data sharing, protection against data spoofing, etc., as compared to traditional security mechanism i.e. a single technology having a number of features. In simple words, smart healthcare will only be possible if both the accuracy in results, security and privacy of such results will be equally maintained. In a nutshell, the primary goal of this book is to offer a variety of techniques for a broad readership, ranging from computing and methodologies to business analytics in the health sciences.

In the chapter titled, “Blockchain Associated Machine Learning Approach for Earlier Prognosis and Preclusion of Osteoporosis in Elderly”, the authors discuss a fully automated mechanism for suspecting osteoporosis patients, which uses machine learning techniques to improve prognosis and preciseness through various processes. Here, we created an automated method that combines principal component analysis (PCA) and the weighted k-nearest neighbors algorithm (wkNN) to effectively detect, predict, and categorize BMD scores as normal, osteopenia, and osteoporosis.

In the chapter titled, “Online Detection of Malnutrition-Induced Anemia from Nail Color using Machine Learning Algorithms”, the author proposed a noninvasive online-based malnutrition-induced anaemia detection using a smartphone App for remotely measuring and monitoring anaemia and malnutrition in humans. This painless method enables user-friendly measurements of human bloodstream parameters such as haemoglobin (Hb), iron, folic acid, and vitamin B12 by embedding intelligent image processing algorithms that will process photos of fingernails captured by the camera in the smartphone, thereby providing a contact-free measurement system during this Covid 19 pandemic.

In the chapter titled, “Artificial Intelligence and Bioinformatics Promise Smart and Secure Healthcare: A Covid-19 Perspectives”, the authors elaborate on the principle, procedure and applications of AI equipped with bioinformatics knowledge to create opportunities, and prospects and answer the challenges met by academicians, researchers, students and industry professionals from the background of computer science, bioinformatics, and healthcare.

In the chapter titled, “Detection of Breast Cancer using Context-Aware Capsule Neural Network”, the authors' primary focus in this work is on the extraction of the features of the images and to accomplish this work, 3D mammogram images are pre-processed. Noise is removed and these preprocessed images are further passed through different convolution layers. After convolution process is done, images are fed to the capsule layers for final classification.

In the chapter titled, “Enhancement of Breast Cancer Screening through Texture and Deep Feature Fusion Model using MLO and CC View Mammograms”, the authors’ proposed model is more concentrated on the extraction and fusion of deep features from the two views to improve screening efficacy. The efficacy of the model is evaluated on mammogram images taken from MLO view and CC views of the DDSM data set. Medical imaging-based ML techniques are commonly used for breast cancer detection and diagnosis, but they are time-consuming.

In the chapter titled, “Artificial Intelligence Assisted Colonoscopy in Diagnosis of Colorectal Cancer”, the authors discuss how AI has gained attention for its potential to improve standard clinical practice. One such use is in diagnostic colonoscopy, where it can help identify precancerous lesions early and permit appropriate care.

In the chapter titled, “Developing a Smart Device for the Manufacturing of Health Products for Patients Using the Internet of Things”, healthcare analytics in a connected world were briefly discussed. In this study, the causes of the creation of contemporary healthcare are methodically examined, along with its causes, methods, and effects.

The authors of the chapter titled, “Blockchain Security in Healthcare” discuss the security and privacy needs, threats, and solution strategies in healthcare Blockchain for the exchange of electronic medical data, which further aids healthcare professionals, healthcare service developers, and healthcare consumers in gaining a thorough understanding of the security and privacy requirements and technologies for enabling a secure and decentralized EMR data sharing.

In this chapter titled, “Enhancing the Communication of Speech Impaired People using Embedded Vision Based Gesture Recognition through Deep Learning”, the author proposes to employ an image-based recognition system for American Sign Language (ASL) namely, (i). classification of handcrafted features using Machine Learning methods, (ii) classification utilising a pre-trained model via transfer learning, and (iii) classification of deep features derived from a specific layer by machine learning classifiers.

The chapter titled, “Advancing Data Science: A New Ray of Hope to Mental Health Care” examines the contributions of AI/ML and Blockchain to several mental healthcare system domains and discusses its potential in many additional unexplored frontiers in this discipline.

The chapter titled, “Machine Learning Based Techniques for Pneumonia Disease Identification in the Health Industry”, discusses the applications of one of the AI sub-disciplines, ML, and the difficulties and obstacles that researchers encounter when identifying early-stage pneumonia disease. In conclusion, Blockchain technology combined with ML and DL may be useful to create safe diagnostic systems as cloud systems have grown to be a possible hazard due to the accumulation of data stored there.

In the chapter titled, “Framework towards Smart Healthcare Tourism based on the Internet of Medical Things (IoMT)”, the authors provide the outlines of the Internet of Things-based health monitoring system that may be helpful for foreign visitors and hotel management throughout maintaining the health of both its guests and staff. The system will identify and examine the body’s many vital signs before telling the operator of the condition of each person’s health.

This chapter titled, “Unmasking the Sentiments of People Towards Pandemic: Twitter Sentiment Analysis in Real Time”, aims at examining and assessing people’s feelings and sentiments throughout the coronavirus outbreak. The study analysed people’s sentiments on the COVID-19 pandemic among Indians using sentimental analysis from tweets collected on Twitter.

In the chapter titled “Application of Industry 4.0: AI and IoT to Improve Supply Chain Performance”, the author briefs about how Artificial Intelligence and the Internet of Things play a vital role in enhancing supply chain management specifically in the healthcare industry. The businesses may streamline operations, cut expenses, and enhance decision-making by utilizing such emerging technologies.

Arvind K. Sharma Shoolini University Solan, Himachal Pradesh IndiaDalip Kamboj Maharishi Markandeshwar (Deemed to be University) Mullana-Ambala, Haryana IndiaSavita Wadhawan Maharishi Markandeshwar (Deemed to be University) Mullana-Ambala, Haryana IndiaGousia Habib Department of Computer Science National Institute of Technology Srinagar Srinagar IndiaSamiya Khan School of Computing and Mathematical Sciences University of Greenwich London, UK &Valentina Emilia Balas Department of Automation and Applied Informatics Aurel Vlaicu University Arad, Romania

List of Contributors

A. GanesanDepartment of Electronics and Electrical Engineering, RRASE College of Engineering, Chennai, IndiaAashna MehtaInter Continental Omni-Research in Medicine Collaborative, Berlin, GermanyAnitya GuptaShoolini University, Himachal Pradesh, IndiaArunprasath ThiyagarajanDepartment of Biomedical Engineering, Kalasalingam Academy of Research and Education, Krishnankoil, Tamil Nadu, IndiaArda IsikInter Continental Omni-Research in Medicine Collaborative, Berlin, GermanyS. Arun KumarDepartment of Electronics and Communication Engineering, Kumaraguru College of Technology, Coimbatore, IndiaAyush AnandInter Continental Omni-Research in Medicine Collaborative, Berlin, GermanyEmmanuel GabrielTulas Institute Dehradun, Uttrakhand, IndiaGanesan VenkatasubramanianDepartment of Psychiatry, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, IndiaGautam AmiyaDepartment of Computer Science and Engineering, Kalasalingam Academy of Research and Education, Krishnankoil, Tamil Nadu, IndiaGousia HabibDepartment of CSE, National Institute of Technology Srinagar, IndiaHanumant Singh ShekhawatDepartment for Electronics and Electrical Engineering, Indian institute of technology, Guwahati, Assam, IndiaHeli PatelInter Continental Omni-Research in Medicine Collaborative, Berlin, GermanyHelen HuangInter Continental Omni-Research in Medicine Collaborative, Berlin, GermanyImtiaz AhmedDepartment of CSE, National Institute of Technology Srinagar, IndiaJins K. AbrahamDepartment of Biotechnology, School of Bio, Chemical and Processing Engineering, Kalasalingam Academy of Research and Education (deemed to be) University, Anand Nagar, Krishnankoil, Tamil Nadu, IndiaJyi Cheng NgInter Continental Omni-Research in Medicine Collaborative, Berlin, GermanyK. SujathaDepartment of Biomedical Engineering/EEE, Dr. M.G.R. Educational and Research Institute, Maduravoyal, Chennai, IndiaKamlesh JoshiTulas Institute Dehradun, Uttrakhand, IndiaKanu GoyalMaharishi Markandeshwar Institute of Physiotherapy and Rehabilitation, Maharishi Markandeshwar (Deemed To Be University), Mullana-Ambala, Haryana, IndiaKatherine CandelarioInter Continental Omni-Research in Medicine Collaborative, Berlin, GermanyKiran BagaliDepartment of Psychiatry, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, IndiaKottaimalai RamarajDepartment of Computer Science and Engineering, Kalasalingam Academy of Research and Education, Krishnankoil, Tamil Nadu, IndiaMalik IshfaqDepartment of Mathematics, University of Kashmir, IndiaManu GoyalMaharishi Markandeshwar Institute of Physiotherapy and Rehabilitation, Maharishi Markandeshwar (Deemed To Be University), Mullana-Ambala, Haryana, IndiaMohit ChhabraDepartment of Computer Science and Engineering, Maharishi Markandeshwar (Deemed to be University), Mullana-Ambala, Haryana, IndiaMuneeswaran VasudevanDepartment of Computer Science and Engineering, Kalasalingam Academy of Research and Education, Krishnankoil, Tamil Nadu, IndiaMuhammad Jawad ZahidInter Continental Omni-Research in Medicine Collaborative, Berlin, GermanyN. ArunDepartment of Electronics and Communication Engineering, Kumaraguru College of Technology, Coimbatore, IndiaN. KanyaDepartment of Information Technology, Dr. M.G.R Educational and Research Institute, Maduravoyal, Chennai, IndiaNeha SharmaDepartment of Management, Maharaja Agrasen Institute of Technology, New Delhi, IndiaNidhi RaniChitkara College of Pharmacy, Chitkara University, Punjab, IndiaNPG. BhavaniSaveetha School of Engineering, SIMATS, Chennai, IndiaOmerah YousufDepartment of CSE, National Institute of Technology Srinagar, IndiaPankaj Kumar VarshneyDepartment of Computer Science, Institute of Information Technology and Management, New Delhi, IndiaPallikonda Rajasekaran MuruganDepartment of Computer Science and Engineering, Kalasalingam Academy of Research and Education, Krishnankoil, Tamil Nadu, IndiaPooja KhuranaDepartment of Applied Sciences, Manav Rachna International Institute of Research and Studies, Faridabad, IndiaPramod Kumar YadavDepartment of CSE, National Institute of Technology Srinagar, IndiaPreeti RanaTulas Institute Dehradun, Uttrakhand, IndiaRajneesh KumarDepartment of Computer Science and Engineering, Maharishi Markandeshwar (Deemed to be University), Mullana-Ambala, Haryana, IndiaRujuta ParlikarDepartment of Psychiatry, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, IndiaS. Sheik AsrafDepartment of Biotechnology, School of Bio, Chemical and Processing Engineering, Kalasalingam Academy of Research and Education (deemed to be) University, Anand Nagar, Krishnankoil, Tamil Nadu, IndiaS. SasikalaDepartment of Electronics and Communication Engineering, Kumaraguru College of Technology, Coimbatore, IndiaSheik AbdullahDepartment of Computer Science and Engineering, Kalasalingam Academy of Research and Education, Krishnankoil, Tamil Nadu, IndiaShalini MohanDepartment of Biotechnology, School of Bio, Chemical and Processing Engineering, Kalasalingam Academy of Research and Education (deemed to be) University, Anand Nagar, Krishnankoil, Tamil Nadu, IndiaShakuntla SinglaDepartment of Mathematics and Humanities, M.M. Engineering College, Maharishi Markandeshwar (deemed to be) University, Mullana-Ambala, IndiaShrawan KumarYogananda School of Artificial Intelligence, Computers and Data Science, Shoolini University, Solan, Himachal Pradesh, IndiaSucharu AsriInter Continental Omni-Research in Medicine Collaborative, Berlin, GermanyT. Kalpatha ReddyElectronic and Communication Engineering Department, S. V. Engineering College, Thirupathi, IndiaTabiya Manzoor BeighDepartment of Computer Science, Pondicherry University, Puducherry, IndiaThirumuruganConsultant Orthopaedic Surgeon, MGR Medical University, Chennai, Tamil Nadu, IndiaToufik-Abdul RahmanInter Continental Omni-Research in Medicine Collaborative, Berlin, GermanyVanteemar S. SreerajDepartment of Psychiatry, National Institute of Mental Health and Neurosciences, Bengaluru, Karnataka, IndiaVishnuvarthanan GovindarajDepartment of Biomedical Engineering, Kalasalingam Academy of Research and Education, Krishnankoil, Tamil Nadu, IndiaVicto Sudha GeorgeDepartment of Computer Science and Engineering, Dr. M.G.R. Educational and Research Institute, Maduravoyal, Chennai, IndiaVikas BhararaDepartment of Commerce, Institute of Information Technology and Management, New Delhi, IndiaVladyslav SikoraInter Continental Omni-Research in Medicine Collaborative, Berlin, GermanyWireko Andrew AwuahInter Continental Omni-Research in Medicine Collaborative, Berlin, GermanyYu-Dong ZhangSchool of Informatics, University of Leicester, Leicester, LE1 7RH, United Kingdom

Blockchain Associated Machine Learning Approach for Earlier Prognosis and Preclusion of Osteoporosis in Elderly

Kottaimalai Ramaraj1,Pallikonda Rajasekaran Murugan1,*,Gautam Amiya1,Vishnuvarthanan Govindaraj2,Muneeswaran Vasudevan1,Thirumurugan3,Yu-Dong Zhang4,Sheik Abdullah1,Arunprasath Thiyagarajan2
1 Department of Computer Science and Engineering, Kalasalingam Academy of Research and Education, Krishnankoil, Tamil Nadu, India
2 Department of Biomedical Engineering, Kalasalingam Academy of Research and Education, Krishnankoil, Tamil Nadu, India
3 Consultant Orthopaedic Surgeon, MGR Medical University, Chennai, Tamil Nadu, India
4 School of Informatics, University of Leicester, Leicester, LE1 7RH, United Kingdom

Abstract

Osteoporosis (OP), or porous bone, is a severe illness wherein an individual's bones weaken, increasing the likelihood of fractures. OP is caused by micro-architectural degradation of bone tissues, which raises the probability of bone fragility and can result in bone fractures even when no force is placed on it. Estimating bone mineral density (BMD) is a prevalent method for detecting OP. For women who have reached menopause, prompt and precise forecasts and preventative measures of OP are essential. BMD can be measured using imaging methods like Computed Tomography (CT) and Dual Energy X-ray Absorptiometry (DEXA/DXA). Blockchain (BC) is a revolutionary technique utilized in the health sector to store and share patient information between clinics, testing centres, dispensaries, and practitioners. The application of Blockchain could detect drastic and even serious errors. As an outcome, it may improve the confidentiality and accessibility of medical information interchange in the medical field. This system helps health organizations raise awareness and enhance the evaluation of health records. By integrating blockchain technology with machine learning algorithms, various bone ailments, including osteoporosis and osteoarthritis, can be identified earlier, which delivers a report regarding the prediction of fracture risk. The developed system can assist physicians and radiologists in making more rapid and better diagnoses of the affected ones. In this work, we developed a completely automated mechanism for suspicious osteoporosis patients that uses machine learning techniques to improve prognosis and precision via different processes. Here, we developed a computerized system that effectively integrates princi-

pal component analysis (PCA) with the weighted k-nearest neighbours algorithm (wkNN) to identify, predict, and classify the BMD scores as usual, osteopenia, and osteoporosis. The ranked results are validated with the DEXA scan results and by the clinicians to demonstrate the efficacy of the machine learning techniques. The laboratories use BC to safely and anonymously share the findings with the patients and doctors.

Keywords: Blockchain (BC) technology, Bone mineral density (BMD), Dual energy X-ray absorptiometry (DEXA/DXA), Osteoporosis (OP), Principal component analysis (PCA), Weighted k-nearest neighbours algorithm (wkNN).
*Corresponding author Pallikonda Rajasekaran Murugan: Department of Computer Science and Engineering, Kalasalingam Academy Of Research And Education, Krishnankoil, Tamil Nadu, India; E-mail: [email protected]