Nanomaterials in Clinical Therapeutics E-Book
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- Herausgeber: John Wiley & Sons
- Kategorie: Wissenschaft und neue Technologien
- Sprache: Englisch
NANOMATERIALS IN CLINICAL THERAPEUTICS In this rapidly developing field, the book focuses on the practical elements of nanomaterial creation, characterization, and development, as well as their usage in clinical research. Nanotechnology-based applications is a rapidly growing field encompassing a diverse range of disciplines that impact our daily lives. Nanotechnology is being used to carry out large-scale reactions in practically every field of biotechnology and healthcare. The incredible progress being made in these applications is particularly true for the healthcare sector, where they are used in cancer detection and treatment, medical implants, tissue engineering, and so forth. Expansions in this discipline are expected to continue in the future, resulting in the creation of a variety of life-saving medical technology and treatment procedures. The primary goal of this book is to disseminate information on nanotechnology's applications in the biological sciences. A broad array of nanotechnological approaches utilized in different biological applications are highlighted in the book's 17 chapters, including the employment of nanotechnology in drug delivery. The first three chapters provide an overview of the history and principles of nanotechnology. The synthesis, characterization, and applications of nanomaterials are covered in the next 10 chapters. The last four chapters discuss the use of nanomaterials in clinical research. Audience The book will be useful for researchers and graduate students in the many areas of science such as biomedicine, environmental biotechnology, bioprocess engineering, renewable energy, chemical engineering, nanotechnology, biotechnology, microbiology, etc.
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Veröffentlichungsjahr: 2022
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Table of Contents
Cover
Series Page
Title Page
Copyright Page
Preface
Part 1: HISTORY AND BASIC PRINCIPLES OF NANOTECHNOLOGY
1 Introduction to Nanotechnology
1.1 Introduction
1.2 Nanoscale Materials: Importance
1.3 Nanotechnology: Historical Advances
1.4 Nanofabrication Methods in Nanotechnology
1.5 Carbon Nanoallotropes
1.6 Classification of the Nanomaterials
1.7 Applications of Nanotechnology
1.8 Conclusions and Future Perspectives
Acknowledgment
References
2 Functional Principal of Nanotechnology in Clinical Research
2.1 Introduction
2.2 Nanoparticles
2.3 Carbon-Based Nanoparticles
2.4 Metal Nanoparticles
2.5 Magnetic Nanoparticles
2.6 Ceramic Nanoparticles
2.7 Lipid Nanoparticles
2.8 Polymeric Nanoparticles (Nanoparticles Made of Polymers)
2.9 Hydrogel
2.10 Nanofibers
2.11 Nanocomposites
2.12 Nanotechnologies for Clinical Laboratory Diagnosis
2.13 Clinical Uses of Nanotechnology
2.14 Nanofilm Applications
2.15 Nanomedicine Implementation
2.16 Future Prospects
2.17 Conclusion
References
3 Application of Nanotechnology in Clinical Research: Present and Future Prospects
3.1 Introduction
3.2 Scope of Nanotechnology in Clinical Research
3.3 Classification
3.4 Applications of Nanotechnology
3.5 Conclusion
Acknowledgment
References
Part 2: SYNTHESIS, CHARACTERIZATION AND APPLICATIONS OF NANOMATERIALS
4 Fermentation Process Versus Nanotechnology
4.1 Overview of Microbial Technology
4.2 Nanotechnology
4.3 Biogenic Sources
4.4 The Extent of Biogenic Nanoparticles in Industrial Sectors
References
5 Application of Geno-Sensors and Nanoparticles in Gene Therapy: A New Avenue for Gene Delivery
5.1 Introduction
5.2 Inorganic Nanomaterials and Their Application in Gene Delivery
5.3 Carbon-Based Nanotubes and Their Applications in Gene Delivery
5.4 Polymer-Based Nanomaterials and Their Applications in Gene Delivery
5.5 Protein, Lipid, and Peptide-Based Nanomaterials and Their Advantages for Gene Delivery
5.6 Conclusion: Challenges and Outlook
References
6 Flexuous Plant Viruses as Nanomaterials for Biomedical Applications
6.1 Introduction
6.2 Plant Virus Particle Structures
6.3 Virus Nanoparticles and Virus-Like Particles
6.4 Production Platforms for VNPs and VLPs
6.5 Functionalization of Viruses
6.6 Uses of Flexuous Plant Viruses in Medicine
6.7 Conclusions
References
7 Role of Plants in Nanoparticle Synthesis
7.1 Introduction
7.2 Characterization of Nanoparticles
7.3 Classification of Nanoparticles
7.4 Biochemical Synthesis of Nanoparticles
7.5 Green Synthesis Approach for NPs
7.6 Plants’ Role in the Green Synthesis of NPs
7.7 Green Synthesis Using Enzymes
7.8 Nanoparticles Role in Photosynthesis
7.9 Applications of Green Synthesis NPs
7.10 Conclusion
References
8 Static DNA Nanostructures and Their Applications
8.1 Introduction
8.2 Static DNA Nanostructures
8.3 DNA Origami Nanostructure
8.4 DNA Polyhedra
8.5 DNA-Functionalized Nanoparticles
8.6 Stability in Biological Fluid and Cellular Uptake of DNA-NSs and DNA-NPs
8.7 Application
References
9 Protein-Based Nanostructures
9.1 Introduction
9.2 Peptide-Based Nanoparticle
9.3 Protein-Based Nanostructure
9.4 Application of Protein-Based Nanostructures in Therapeutics
References
10 Nanocomposites-Based Biodegradable Polymers
10.1 Introduction
10.2 Nanocomposite
10.3 Biodegradable Polymer
10.4 Biopolymer
10.5 Nanofillers
10.6 Cellulose and Its Sources
10.7 Nanocellulose
10.8 Nanocellulose Composite Processing
10.9 Nanocomposites Used as Packaging Materials
10.10 Future Perspective and Application
10.11 Conclusions
References
11 Instrumentation for the Analysis and Characterization of Nanomaterials
11.1 Introduction
11.2 Scanning Electron Microscopy [SEM]
11.3 Energy Dispersive X-Ray Analysis [EDX]
11.4 Atomic Force Microscopy [AFM]
11.5 Transmission Electron Microscopy [TEM]
11.6 Scanning Tunneling Microscopy [STM]
11.7 Ultraviolet-Visible Spectroscopy
11.8 Raman Spectroscopy
11.9 Fourier Transform Infrared Spectroscopy
11.10 X-Ray Diffraction [XRD]
11.11 X-Ray Photoelectron Spectroscopy [XPS]
11.12 Zeta Potential
11.13 Conclusions
References
12 Application of Microbial Nanoparticles
12.1 Introduction
12.2 Categorization of Nanoparticles
12.3 Microbial-Mediated Synthesis of Nanoparticles for Therapeutic and Biomedical Applications
12.4 Agriculture and Food Nanotechnology
12.5 Role of Nanoparticles in the Medical Field
12.6 Application of Microbial Nanoparticles
12.7 Conclusion
References
13 Bio-Nanostructures: Applications and Perspectives
13.1 Introduction
13.2 Classification of Nanostructures
13.3 Characterization Method of Nanostructures
13.4 Applications of Bio-Nanoparticles
13.5 Conclusion
References
Part 3: APPLICATION OF NANOMATERIALS IN CLINICAL RESEARCH
14 Nanomaterials for Tissue Grafting
14.1 Introduction
14.2 Tissue Engineering
14.3 What is Nanotechnology?
14.4 Nanomaterials and Nanoparticles
14.5 Future Prospects
14.6 Conclusion
References
15 Nanoparticles for Cancer Therapy
15.1 Introduction
15.2 Nanoparticles as Drug Delivery in Cancer Treatment
15.3 Drug Nanocarriers Classification
15.4 Organic Nanocarriers
15.5 Tumor Targeting by Nanoparticles
15.6 Utilization of Nanoparticles in Imaging and Treatment for Cancer
15.7 Use of Nanoparticles in the Diagnosis and Treatment of Breast Cancer
15.8 The Use of Nanoparticles in the Diagnosis and Treatment of Brain Cancer
15.9 Conclusion
References
16 Nanoantibiotics
16.1 Introduction
16.2 Nanoantibiotics—A Potent Alternative to Antibiotics?
16.3 Developmental Strategy of Nanoantibiotics Over Antibiotics
16.4 Mechanism of Action of Nanoantibiotics
16.5 Common Functions of Nanoantibiotics
16.6 Nanomaterials—A Suitable Source of Nanoantibiotics
16.7 Types of Nanoantibiotics
16.8 Advantages of Nanoantibiotics
16.9 Disadvantages of Nanoantibiotics
16.10 Treatment of Multidrug-Resistant Bacteria with Nanoantibiotics
16.11 Treatment of Methicillin-Resistant
Staphylococcus aureus
with Nanoantibiotics
16.12 Development of Targeted Therapy Using Nanoantibiotics
16.13 Future Prospects of Nanoantibiotics
16.14 Conclusion
References
17 Theranostic Nanomaterials and Its Use in Biomedicine
17.1 Introduction
17.2 Biomedical Payloads
17.3 Carrier
17.4 Theranostic Nanomaterials and Applications
17.5 Pharmacokinetics and Pharmacodynamics
17.6 Conclusions: Challenges and Future Perspectives
References
Appendix
Index
End User License Agreement
List of Tables
Chapter 3
Table 3.1 Different types of nanomaterials in drug delivery.
Chapter 4
Table 4.1 Bacterial synthesis and their cellular machinery.
Table 4.2 Fungal synthesis of nanoparticles and their cellular machinery....
Table 4.3 Green synthesis of nanoparticles and their application.
Table 4.5 Nanocarriers based antibiotics used against bacterial biofilm infe...
Table 4.6 List of different techniques for remediation of contaminants.
Table 4.7 Production of commercial nanofood, nanomaterial, and their applica...
Table 4.8 Role of analyte and their applications in food industries.
Chapter 5
Table 5.1 Different synthesis methods of quantum dots and their applications...
Chapter 6
Table 6.1 Particle compositions and characteristics of TMV, PVX and PVY (c...
Chapter 7
Table 7.1 Plants biosynthesis using plants.
Chapter 10
Table 10.1 Types of nanocellulose [34].
Table 10.2 Processing strategy of cellulose nanostructure (CN)-based nanocom...
Chapter 11
Table 11.1 Factors to be considered when determining NPs using UV-vis spec...
Chapter 12
Table 12.1 Industrial application of different nanomaterials synthesized u...
Table 12.2 Synthesis of various nanomaterials using cellular extract of ye...
Table 12.3 Nanomaterials synthesized by using extract of microalgae and th...
Table 12.4 Antimicrobial effect of bacterial silver nanoparticles.
Chapter 13
Table 13.1 Different characterization techniques for nanoparticles.
Chapter 14
Table 14.1 Types of nanoparticles and their applications in therapeutics....
Chapter 17
Table 17.1 Theranostics agents and their functions.
Table 17.2 Theranostic technologies for treatment.
Table 17.3 Overview, advantages, and limitations of the imaging techniques r...
List of Illustrations
Chapter 1
Figure 1.1 Schematic representation of top-down and bottom-up approach [re...
Figure 1.2 Schematic presentation of classification of different allotrope...
Figure 1.3 Classification of nanomaterials [reprinted with permission from...
Figure 1.4 Schematic representation of the application of Plasmon nanomate...
Chapter 2
Figure 2.1 Illustrative representation of different types of NPs used in c...
Figure 2.2 Pictorial representation of different types of lipid NPs used a...
Chapter 3
Figure 3.1 Illustration demonstration of classification of nanosystems.
Figure 3.2 Illustration demonstration of various types of nanosystems.
Figure 3.3 Diagrammatic representation of dendrimers.
Figure 3.4 Applications of NPs in the medical field.
Figure 3.5 Applications of nanosponge in the medical field.
Figure 3.6 Application of nanotechnology in the medical field.
Figure 3.7 Application of nanotechnology in dentistry.
Chapter 4
Figure 4.1 Immobilization techniques of cells.
Figure 4.2 Different shapes of organic and inorganic nanostructures.
Figure 4.3 General schematic diagram of classification of nanoparticles.
Figure 4.4 Biogenic synthesis of nanoparticles and characterization techni...
Chapter 5
Figure 5.1 Magnetic nanoparticles with different surface modifications and...
Figure 5.2 Schematic stages of gene delivery with polymeric cationic polym...
Chapter 7
Figure 7.1 Applications of nanoparticles.
Figure 7.2 Different criteria for nanoparticles.
Figure 7.3 Green synthesis of nanoparticles.
Chapter 8
Figure 8.1 (a) Structure of an immobile 4-arm DNA junction. (b) 2D lattice...
Figure 8.2 (a) Immobile nucleic acid junctions: three-arm, four-arm, five-...
Figure 8.3 2D and 3D DNA assemblies of DNA origami and brick assembly. (a)...
Figure 8.4 Hierarchical assembly of discrete solids with DNA tiles.
Chapter 9
Figure 9.1 Schematic representation: (a) siRNA-peptide nanoparticle format...
Figure 9.2 (a) Capsid structure of CCMV virus particle (PDB 1ZA7). (b) the...
Figure 9.3 (a) Armadillo repeat (PDB 3BCT); (b) HEAT repeat (PDB 3GS3); (c...
Chapter 10
Figure 10.1 Types of biodegradable polymer [23].
Figure 10.2 Types of nanofillers [31].
Figure 10.3 Surfactant mining [47].
Chapter 11
Figure 11.1 Schematic diagram for working principle of TEM [9].
Chapter 12
Figure 12.1 Different physiochemical approaches for synthesis of nanoparti...
Figure 12.2 Schematic representation of used of different nanoproducts in ...
Figure 12.3 Schematic outline for the nanomaterial safety assessment in co...
Chapter 13
Figure 13.1 Applications: nanostructure.
Chapter 14
Figure 14.1 General steps of tissue engineering.
Figure 14.2 Types of tissue grafts.
Chapter 15
Figure 15.1 Nanocomposite mediated drug delivery platforms.
Figure 15.2 Schematic diagram explaining polymerosomes work mechanism.
Chapter 17
Figure 17.1 Theranostic Nanoparticle with surface functionalization and in...
Figure 17.2 Nanotheranostics with photothermal and photodynamic uses.
Figure 17.3 Applications of multifunctional imaging & /therapeutic UCNPs....
Figure 17.4 Schematic illustration of gold nanoparticles as nanotheranosti...
Figure 17.5 Schematic diagram of theranostic nanomaterials with PK-PD look...
Guide
Cover Page
Series Page
Title Page
Copyright Page
Preface
Table of Contents
Begin Reading
Index
Wiley End User License Agreement
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Scrivener Publishing100 Cummings Center, Suite 541JBeverly, MA 01915-6106
Publishers at ScrivenerMartin Scrivener ([email protected])Phillip Carmical ([email protected])
Nanomaterials in Clinical Therapeutics
Synthesis and Applications
Edited by
Mainak Mukhopadhyay
and
Arindam Kuila
This edition first published 2022 by John Wiley & Sons, Inc., 111 River Street, Hoboken, NJ 07030, USA and Scrivener Publishing LLC, 100 Cummings Center, Suite 541J, Beverly, MA 01915, USA© 2022 Scrivener Publishing LLCFor more information about Scrivener publications please visit www.scrivenerpublishing.com.
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Library of Congress Cataloging-in-Publication Data
ISBN 9781119857235
Cover image: Pixabay.ComCover design by Russell Richardson
Preface
Nanotechnology-based applications is a rapidly growing field encompassing a diverse range of disciplines that impact our daily lives. Nanotechnology is being used to carry out large-scale reactions in practically every field of biotechnology and healthcare. The incredible progress being made in these applications is particularly true for the healthcare sector, where they are used in cancer detection and treatment, medical implants, tissue engineering, and so forth. Expansions in this discipline are expected to continue in the future, resulting in the creation of a variety of life-saving medical technology and treatment procedures.
The primary goal of this book is to disseminate information on nano-technology’s applications in the biological sciences. A broad array of nanotechnological approaches utilized in different biological applications are highlighted in the book’s 17 chapters, including the employment of nanotechnology in drug delivery. The first three chapters provide an overview of the history and principles of nanotechnology. The synthesis, characterization, and applications of nanomaterials are covered in the next 10 chapters. The last four chapters discuss the use of nanomaterials in clinical research.
A number of well-known scientists contributed to the book, whose knowledge of the subject will benefit students and researchers in fields such as environmental biotechnology, bioprocess engineering, renewable energy, chemical engineering, nanotechnology, biotechnology, and microbiology.
We are grateful to Linda Mohr and Martin Scrivener at Scrivener Publishing for their complete cooperation and assistance in the timely publishing of this book. We would also like to express our gratitude to the writers and the publication staff for their efforts throughout the COVID-19 epidemic.
Dr. Mainak Mukhopadhyay
Dr. Arindam Kuila
June 2022
