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Beschreibung

Many herbs and spices, in addition to their culinary use for taste, contain chemical compounds which have medicinal uses. For this reason, herbs and spices have been used for treating various ailments since ancient times. Modern scientific methods have enabled researchers to isolate bioactive compounds from herbs and spices and perform chemical analyses, which can be used to develop medicines to treat different diseases. This book series is a compilation of current reviews on studies performed on herbs and spices. Science of Spices and Culinary Herbs is essential reading for medicinal chemists, herbalists and biomedical researchers interested in the science of natural herbs and spices that are common part of regional diets and folk medicine.

The third volume of this series features the following reviews:

1. Anthelmintic Properties of Cinnamon for the Control of Agricultural and Public Health Pests
2. Nutraceutical Attributes of Tamarindus indica L. - Devils’ Tree with Sour Date
3. An Overview of the Tamarind (Tamarindus indica L.) Fruit: A Potential source of Nutritional and Health promoting Phytoconstituents
4. The Clinical Overview of Turmeric, Turmeric-based Medicines, and Turmeric Isolates
5. Origanum majorana: The Fragrance of Health
6. Black Pepper (Piper nigrum L.): The King of Spices
7. Coriander: A Herb with Multiple Benefits
8. Flax Seed (Linum usitatissimum) a Potential Functional Food Source

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Seitenzahl: 329

Veröffentlichungsjahr: 2020

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Table of Contents
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End User License Agreement (for non-institutional, personal use)
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Disclaimer:
Limitation of Liability:
General:
PREFACE
List of Contributors
Anthelmintic Properties of Cinnamon for the Control of Agricultural and Public Health Pests
Abstract
INTRODUCTION
BIOLOGY OF CINNAMON
TRADITIONAL AND MOLECULAR TAXONOMIC DESCRIPTION OF CINNAMON
Traditional Taxonomy
Molecular Taxonomy
METABOLITES REPORTED IN CINNAMON
Volatiles
Leaves
Bark
Root bark
Fruit Stalks
Fruits
Phenolics
Simple Phenolics
Polyphenols
Alkaloids
USES OF CINNAMON AS A CONDIMENT
ANTIPARASITIC PROPERTIES OF CINNAMON
Antiprotozoal Properties of Cinnamon
Activity against Plasmodium falciparum
Activity against Pyroplasmas
Activity against Trypanosoma cruzi
Activity against Schistosoma japonicum
ANTHELMINTIC PROPERTIES AGAINST AGRICULTURAL PESTS
Insecticidal Activity
Mode of Action
Agricultural Pests
Urban and Human Health Pests
Veterinary Pests
ANTHELMINTIC PROPERTIES AGAINST LIVESTOCK PESTS
Productive Performance
ADVANCES AND PERSPECTIVES OF CINNAMON IN THE CONTROL OF HELMINTHS
PERSPECTIVES ON THE STUDY OF THE ANTHELMINTIC PROPERTIES OF CINNAMON
CONCLUSIONS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
Acknowledgements
REFERENCES
Nutraceutical Attributes of Tamarindus indica L. - Devils’ Tree with Sour Date
Abstract
INTRODUCTION
BIOLOGICAL/PHARMACOLOGICAL/NUTRACEUTICAL ACTIVITIES OF SPICES AND CULINARY HERBS
METABOLIC DISORDERS
TUBERCULOSIS
NEPHROTOXICITY
APHRODISIAC ACTIVITY
HEPATOPROTECTIVE ACTIVITY
SNAKEBITE
PHYTOCHEMISTRY OF SPICES AND CULINARY HERBS
STRUCTURE-ACTIVITY RELATIONSHIP (SAR) STUDIES
MOLECULAR DOCKING STUDIES
Stress Biomarkers
Inflammation Biomarkers
Ulcer Biomarkers
Diabetic Biomarkers
Liver Biomarkers
Venom Biomarkers
TAMARIND PROCESSING AND PRODUCTS
Processing and Preservation
Tamarind Products
Pulp
Juice Concentrate
Tamarind-Mango Squash
Tamarind Jam
Spiced Tamarind Beverage
Food Colorant
Quality Aspects of Tamarind
CONCLUSION
ABBREVIATIONS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
An Overview of The Tamarind (Tamarindus indica L.) Fruit: A Potential source of Nutritional and Health Promoting Phytoconstituents
Abstract
INTRODUCTION
Botanical Description and Historical Cultivation
Chemical And Nutritional Composition of Tamarind Fruit
Anti-nutrient Composition of Tamarind
Food Uses of Tamarind
Medicinal Uses of the Tamarind Fruit
Antioxidant Activities of Tamarind Fruit
Antimicrobial Properties of the Tamarind Fruit
Anti-Inflammatory Activities of Tamarind Fruit
Anticancer Activities of Tamarind Fruit
CONCLUSION AND RECOMMENDATIONS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
The Clinical Overview of Turmeric, Turmeric-based Medicines, and Turmeric Isolates
Abstract
INTRODUCTION
CLINICAL STUDIES
Clinical Studies of Turmeric and Turmeric-based Medicine
Arthritis
Asthma
Chemoprevention
Colorectal Cancer
Diabetes Mellitus
Dyslipidemia
Human Gut Microbiota
Lupus Nephritis
Peptic Ulcer
Skin Inflammation
Vascular Function
Clinical Studies of Turmeric Isolates
Alzheimer’s Disease
Beta-Thalassemia
Breast Cancer
Colorectal Cancer
Pancreatic Cancer
Prostate Cancer
Depression
Diabetes Mellitus
Dyslipidemia
Inflammatory Bowel Disease
Metabolic Syndrome (Weight Loss)
Multiple Myeloma
Pancreatitis
Osteoarthritis
Rheumatoid Arthritis
Skin Diseases
Viral Infection
SUMMARY OF CLINICAL TRIAL
ADVERSE EFFECT IN CLINICAL TRIALS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Origanum majorana: The Fragrance of Health
Abstract
INTRODUCTION
Traditional Claims [1-9]
Vernacular Names [10]
DRUG INTERACTIONS [11-14]
PHYTOCHEMISTRY OF Origanum majorana [14-25]
THERAPEUTIC USES [26-29]
Global and Indian Market of Origanum majorana [30, 31]
Import Data [30, 31]
Export of Marjoram Oil [30, 31]
Toxicity of Origanum Majorana [21]
Pharmacology [32-48]
Antioxidant Activity
Antimicrobial Activity
Antigenotoxic Effect
Anti-hyperglycaemic
Anti-depressant
Anti- neurodegenerative Effect
Anti-proliferative Activity
Anti-spasmodic and Myorelaxant Activity
Anti-urolithic Activity (Inhibition of Kidney Stones)
Cardioprotective Activity
Anti-ulcerogenic Activity
Modulation of Polycystic Ovarian Syndrome (PCOS)
Veterinary Applications [49-53]
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Black Pepper (Piper nigrum L.): The King of Spices
Abstract
INTRODUCTION
Pharmacognostic Characteristic of Black pepper Plant
Taxonomical Classification of Piper nigrum
Pharmacological Activities of Black Pepper
Antioxidant Activity
Antimicrobial Activity
Antidiarrheal Activity
Analgesic, Anti-inflammatory and Antipyretic Activity
Anticonvulsant Activity
Anti-Tussive and Bronchodilator Activity
Anticancer and Antitumor Activity
Neuroprotective and Antidepressant Activity
Hepatoprotective Activity and Digestion
Phytochemical Studies
HERBAL FORMULATIONS (TABLE 2)
Traditional and Ethnomedicinal Uses
CONCLUSION
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Coriander: A Herb with Multiple Benefits
Abstract
INTRODUCTION
Taxonomy
Historic Occurrence
About the Plant
CHEMICAL CONSTITUENTS
PROPERTIES AND USES
TRADITIONAL USES
PREPARATION & STORAGE
PHYTOCHEMICAL INVESTIGATIONS
TLC Identity Test
Analysis of Volatile Oil
Limits for Quality Parameters
PHARMACOLOGICAL INVESTIGATIONS
CLINICAL INVESTIGATIONS
DISCUSSION
CONCLUSION
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGMENTS
REFERENCES
Flax Seed (Linum usitatissimum): a Potential Functional Food Source
Abstract
INTRODUCTION
Occurrence and Distribution
TRADITION AND ETHANOMEDICAL USE
PHYTOCHEMICALS
Nutrients Composition of Flaxseed and Health Benefits
Proteins
Dietary Fibers
Minerals
Lignans
Flaxseed Oil/Lipids
Bioactive Compounds
PHARMACOLOGICAL ACTION
Anti-Inflammatory
Antimicrobial
Antioxidant
Antipyretic
Anti-Ulcer
Laxative
Bone Development
Hair Growth
Atherosclerosis
Memory
Cardiovascular Diseases
Blood Pressure
Breast Cancer
Prostate Cancer
Diabetes
Kidney Diseases
CLINICAL AND PRECLINICAL STUDIES (Table 3)
HERBAL FORMULATION AVAILABLE
Linseed Products
Linseed Oil
Linseeds Cake/Meal
Linseed Mucilage
Linseed Tea
Linseed fibers
ANTI-NUTRIENTS
DOSAGE
ADVICE
INTERACTION
CONCLUSIONS
CONSENT FOR PUBLICATION
CONFLICT OF INTEREST
ACKNOWLEDGEMENTS
REFERENCES
Science of Spices and Culinary Herbs
Latest Laboratory, Pre-clinical, and Clinical Studies
(Volume 3) 
Edited by
Atta-ur-Rahman, FRS
Kings College, University of Cambridge,
Cambridge,
UK
M. Iqbal Choudhary & Sammer Yousuf
H.E.J. Research Institute of Chemistry,
International Center for Chemical and Biological Sciences,
University of Karachi,
Karachi,
Pakistan

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PREFACE

Civilizations throughout human history have benefited from the taste, aroma, and benefits of spices and culinary herbs. They contain among the most valued natural products for their culinary and recreational uses and medicinal properties. Many of them have become integral parts of traditional systems of medicine. In recent decades they have been the focus of extensive scientific research. Their remarkable health benefits have been demonstrated through numerous phytochemical, pharmacological and clinical studies.

The 3rd volume of the book series entitled, “Science of Spices and Culinary Herbs” is a compilation of eight excellent review articles, presenting the latest developments in this exciting field of natural product sciences. They cover a whole range of topics, all relevant to the evidence based therapeutic, nutritional, and olfactory uses of common spices and herbs.

The review by Marcelino et al is focused on the anthelmintic properties of cinnamon (Cinnamomom verum J. Presil.). Various helminthes parasites are associated with a plethora of diseases in host plants, farm animals, and humans. Several gastrointestinal diseases are also caused by helminthes is humans. The authors have provided a comprehensive chapter covering the scientific studies on anthelmintic properties of cinnamon and uses in agriculture crops, livestock, and humans. More at al have contributed a chapter on the nutraceutical and other important biological properties of tamarind (Tamarindus indica L.), used globally as a fruit, and as a spice. The authors have presented the advances in phytochemistry and in clinical research on this globally important dietary plant. The next review by Oyetaya and Odeniyi is also focused on the nutritional and health promoting phytochemicals of tamarind. Turmeric (Curcuma longa Linn.) has been the focus of vigorous researches since the last several decades. Sukandar and Ayuningtyas have provided a comprehensive account of recent clinical studies conducted on various turmeric based formulations including its phytoconstituents. The review focuses on the importance of well-designed clinical trials and proper formulations in the context of turmeric based medications. Pimple et al have written a well referenced and well written chapter on culinary and perfumery properties of the famous herb oregano (Origanum majorana Linn.), focusing on its traditional uses, phytochemistry, and on its medicinal and perfumery importance. Soni et al discuss the medicinal constituents of black pepper (Piper nigrum L.), most important among which is piperine a pungent alkaloid. Preclinical pharmacological data supports the therapeutic potential of black pepper and its constituents. Coriander (Coriandrum sativum L.) is a herb of global significance. Upaganlawar et al have focused the recent work on therapeutic importance of this famous herb as well as its phytochemistry and pharmacognosy. Soni and Soni in the last chapter of this volume have reviewed recent work on the increasingly popular spice flax seed (Linum usitatissimum L.). Extensive studies on its nutritional and medicinal constituents followed by pharmacological and preclinical studies, have shown it to be a valuable functional food for physical and mental health.

We gratefully acknowledge scholarly contributions and timely submissions of their review articles by leading experts in this field. We also appreciate the diligent work of Ms. Fariya Zulfiqar (Manager Publications) and Mr. Mahmood Alam (Director Publications) at Bentham Science Publishers. We sincerely hope that this volume will greatly benefit the scientific community interested in the fascinating science of spices and herbs.

Atta-ur-Rahman, FRS Kings College University of Cambridge Cambridge UK
M. Iqbal Choudhary & Sammer Yousuf H.E.J. Research Institute of Chemistry International Center for Chemical and Biological Sciences University of Karachi Karachi, Pakistan

List of Contributors

Devi Aishwarya T., Department of Biotechnology Sri Jayachamarajendra College of EngineeringJSS Science and Technology University, JSS Research Foundation, SJCE CampusManasagangothri, Mysore - 570 006, KarnatakaIndiaUpaganlawar Aman, SNJB's SSDJ College of PharmacyNeminagar, Chandwad 423 101IndiaKulkarni Amrita M., P. E. Society’s Modern College of PharmacyYamunanagar, Nigdi-411044, PuneIndiaPatil Anirudh Gururaj, School of Basic and Applied Sciences, Department of Biological SciencesDayananda Sagar University, Shavige Malleshwara HillsKumaraswamy Layout, Bengaluru - 560 111, KarnatakaIndiaSinghai Ashish, Faculty of PharmacyVNS Group of InstitutionsBhopal 462044IndiaNogueda-Torres Benjamín, Escuela Nacional de Ciencias BiológicasInstituto Politécnico Nacional. Prolongación de Carpio y Plan de Ayala s/n, Miguel HidalgoSanto Tomás, 11340 Ciudad deMéxicoPimple Bhushan P., P. E. Society’s Modern College of PharmacyYamunanagar, Nigdi-411044, PuneIndiaAguilar-Figueroa Blanca, Escuela Nacional de Ciencias BiológicasInstituto Politécnico Nacional. Prolongación de Carpio y Plan de Ayala s/n, Miguel HidalgoSanto Tomás, 11340 Ciudad deMéxicoÁlvarez-Fernández Blanca E., Facultad de Ciencias Químico Biológicas de la Universidad Autónoma de GuerreroLázaro Cárdenas, S/N. Ciudad UniversitariaChilpancingo, Guerrero, C.P. 39090MéxicoAyuningtyas Dhyan K., Department of Pharmacology and Clinical Pharmacy, School of PharmacyBandung Institute of TechnologyBandungIndonesiaSukandar Elin Y., Department of Pharmacology and Clinical Pharmacy, School of PharmacyBandung Institute of TechnologyBandungIndonesiaZameer Farhan, School of Basic and Applied Sciences, Department of Biological SciencesDayananda Sagar University, Shavige Malleshwara HillsKumaraswamy Layout, Bengaluru - 560 111, KarnatakaIndiaOyetayo F. Lucy, Department of BiochemistryEkiti State UniversityAdo-Ekiti, Ekiti StateNigeriaOropeza-Guzman Gabriela, Escuela Nacional de Ciencias BiológicasInstituto Politécnico Nacional. Prolongación de Carpio y Plan de Ayala s/n, Miguel HidalgoSanto Tomás, 11340 Ciudad deMéxicoCastañeda-Ramirez Gloria Sarahi, Centro Nacional de Investigación Disciplinaria en Salud Animal e InocuidadINIFAP, Km 11 Carretera Federal Cuernavaca-CuautlaNo. 8534, Col. Progreso, Jiutepec, Morelos, CP 62550MéxicoHernández-Bolio Gloria Ivonne, Departamento de Recursos del MarCentro de Investigación y de Estudios Avanzados del Instituto Politécnico NacionalUnidad MéridaMéxicoSilva-Aguayo Gonzalo, Departamento de Producción Vegetal, Facultad de AgronomíaUniversidad de ConcepciónVicente Méndez 595, ChillánChileVentura-Cordero Javier, School of Biological SciencesQueen´s University BelfastChlorine Gardens, Belfast, BT95BLUKMuthucheliyan K., School of Basic and Applied Sciences, Department of Biological SciencesDayananda Sagar University, Shavige Malleshwara HillsKumaraswamy Layout, Bengaluru - 560 111, KarnatakaIndiaKhan Kounaina, Department of DravyagunaJSS Ayurvedic Medical CollegeLalithadripura, Mysuru - 570 028, KarnatakaIndiaAguilar-Marcelino Liliana, Centro Nacional de Investigación Disciplinaria en Salud Animal e InocuidadINIFAP, Km 11 Carretera Federal Cuernavaca-CuautlaNo. 8534, Col. Progreso, Jiutepec, Morelos, CP 62550MéxicoCarrillo-Morales Manuel, Universidad Politécnica del Estado de MorelosBoulevard Cuauhnáhuac #566 Col. Lomas del Texcal, C.P.62550, Jiutepec, MorelosMéxicoAvinash M.G., Department of Studies in MicrobiologyUniversity of MysoreManasagangotri, Mysore – 570 006, KarnatakaIndiaNagendra M.N., Department of Biotechnology, Sri Jayachamarajendra College of EngineeringJSS Science and Technology University, JSS Research Foundation, SJCE CampusManasagangothri, Mysore - 570 006, KarnatakaIndiaChoudhary Naveen Kumar, Department of PharmacognosyHead of Herbal drug Research in B. R. Nahata College of PharmacyMandsaur, M.P.IndiaSatapathy Pankaj, School of Basic and Applied Sciences, Department of Biological SciencesDayananda Sagar University, Shavige Malleshwara HillsKumaraswamy Layout, Bengaluru - 560 111, KarnatakaIndiaSoni Priyanka, Department of PharmacognosyHead of Herbal drug Research in B. R. Nahata College of PharmacyMandsaur, M.P.IndiaBhor Ruchita B., P. E. Society’s Modern College of PharmacyYamunanagar, Nigdi-411044, PuneIndiaAishwarya S., School of Basic and Applied Sciences, Department of Biological SciencesDayananda Sagar University, Shavige Malleshwara HillsKumaraswamy Layout, Bengaluru - 560 111, KarnatakaIndiaVeena S.M., Department of BiotechnologySapthagiri College of EngineeringBangalore - 560 057IndiaGopal Shubha, Department of BiotechnologySapthagiri College of EngineeringBangalore - 560 057IndiaGopal Shubha, Department of Studies in MicrobiologyUniversity of MysoreManasagangotri, Mysore – 570 006, KarnatakaIndiaHudeda Shivaprasad, Department of DravyagunaJSS Ayurvedic Medical CollegeLalithadripura, Mysuru - 570 028, KarnatakaIndiaMore Sunil S., School of Basic and Applied Sciences, Department of Biological SciencesDayananda Sagar University, Shavige Malleshwara HillsKumaraswamy Layout, Bengaluru - 560 111, KarnatakaIndiaSoni Vishal, Department of PharmacognosyHead of Herbal drug Research in B. R. Nahata College of PharmacyMandsaur, M.P.IndiaDhote Vipin, Faculty of PharmacyVNS Group of InstitutionsBhopal 462044India

Anthelmintic Properties of Cinnamon for the Control of Agricultural and Public Health Pests

Gloria Sarahi Castañeda-Ramirez1,Javier Ventura-Cordero2,Gloria Ivonne Hernández-Bolio3,Gonzalo Silva-Aguayo4,Manuel Carrillo-Morales5,Gabriela Oropeza-Guzman6,Blanca Aguilar-Figueroa6,Benjamín Nogueda-Torres6,Blanca E. Álvarez-Fernández7,Liliana Aguilar-Marcelino1,*
1 Centro Nacional de Investigación Disciplinaria en Salud Animal e Inocuidad, INIFAP, Km 11 Carretera Federal Cuernavaca-Cuautla, No. 8534, Col. Progreso, Jiutepec, Morelos, CP 62550, México
2 School of Biological Sciences, Queen´s University Belfast, Chlorine Gardens, Belfast, BT95BL, UK
3 Departamento de Recursos del Mar, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Unidad Mérida, México
4 Departamento de Producción Vegetal, Facultad de Agronomía, Universidad de Concepción, Vicente Méndez 595, Chillán, Chile
5 Universidad Politécnica del Estado de Morelos, Boulevard Cuauhnáhuac #566, Col. Lomas del Texcal, C.P.62550, Jiutepec, Morelos, México
6 Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional. Prolongación de Carpio y Plan de Ayala s/n, Miguel Hidalgo, Santo Tomás, 11340 Ciudad de México, CDMX, México
7 Facultad de Ciencias Químico Biológicas de la Universidad Autónoma de Guerrero, Av. Lázaro Cárdenas, S/N. Ciudad Universitaria, Chilpancingo, Guerrero, C.P. 39090, México

Abstract

The most prevalent helminths are the gastrointestinal nematodes, such as the parasitic nematode Haemonchus contortus of sheep. Other economically important nematodes are phytoparasites, Nacobbus aberrans and Meloidogyne incognita, affecting more than 200 crops of plants and vegetables such as tomatoes, among others. Regarding the cestodes and Hymenolepis nana are the most prevalent worldwide. These helminths occur in warm temperate and dry geographical areas of developing countries with poor sanitary habits affecting mainly children between 2-8 years old. The conventional control is the use of anthelmintics (e.g. macrocyclic lactones, benzimidazoles and imidazoles) of synthetical origin; however, the misuse of these anthelmintics has led to a problem of chemical resistance worldwide; in addition,

the residuality of these compounds in sheep byproducts, such as meat and milk, has caused a negative environmental impact. They also damage populations of beneficial organisms, such as the dung beetle, earthworms and nematophagous mites, among others. Hence, it is urgent and necessary to search for other integral, environmentally friendly, and sustainable control methods. The use of medicinal plants, mainly spices and culinary herbs, could be a sustainable alternative to control helminths that affect humans, plants and animals. This chapter presents an overview of the anthelmintic properties of cinnamon for sustainable helminth parasites control. This chapter is divided into several topics including 1) biology of cinnamon, 2) traditional and molecular taxonomic description of cinnamon, 3) metabolites reported in cinnamon, 4) uses of cinnamon as a condiment, 5) antiparasitic properties of cinnamon, 6) anthelmintic properties against agricultural pests, 7) anthelmintic properties against livestock pests and productive performance, 8) advances and perspectives of cinnamon in the control of anthelmintic properties, and 9) perspectives on the study of the anthelmintic properties of cinnamon.

Keywords: Anthelmintic properties, Cinnamomum verum, Culinary herbs, Spices, Soil-transmitted helminthes.
*Corresponding author L. Aguilar-Marcelino: Centro Nacional de Investigación Disciplinaria en Salud Animal e Inocuidad, INIFAP, Km 11 Carretera Federal Cuernavaca-Cuautla, No. 8534, Col. Progreso, Jiutepec, Morelos, CP 62550, México; Tel: +52 777 319 28 60 Ext. 121; Fax: +52 777 319 28 48, Ext. 129; E-mail: [email protected]