Two-Dimensional Nanomaterials for Biosensing and Imaging Applications E-Book

• Herausgeber: John Wiley & Sons
• Kategorie: Fachliteratur
• Sprache: Englisch

Seitenzahl: 1219

Veröffentlichungsjahr: 2025

Beschreibung

The book is essential for anyone eager to understand the transformative potential of 2D nanomaterials in biotechnology and medical science, offering in-depth insights into their unique properties, synthesis methods, and practical applications in an ever-evolving field.

Nanotechnology is pivotal in advancing biotechnology and medical science. Nanomaterials, essential components of this technology, showcase unique and superior physicochemical properties when compared to their bulk equivalents. Since the groundbreaking discovery of graphene in 2004, two-dimensional (2D) nanomaterials have garnered immense attention for their potential in a wide range of applications across multiple industries including biochemistry, biophysics, and engineering. Two-Dimensional Nanomaterials for Biosensing and Imaging Applications examines the current state and new challenges associated with the development of 2D nanomaterials for biosensing and imaging applications. This volume focuses on the synthesis, processing methods, characterization, properties, and applications of 2D nanomaterials, their nanocomposites or heterostructures for biosensors and imaging devices, and the essential criteria in each specified field. Comparative performance evaluations of various biosensor devices and their advantages and disadvantages for the commercialization of 2D materials-based biosensors are comprehensively covered, giving essential insight into the challenges this technology presents. A handpicked selection of topics and expert contributors from across the globe will make this book an outstanding resource for students and industry professionals looking to explore the potential of these ground-breaking materials.

Readers will find the book:

• Provides a comprehensive overview of the synthesis, processing, compositions, structure, device design, and various properties of two-dimensional nanomaterials for biosensing and imaging applications;
• Comprehensively covers 2D materials and their processing techniques, properties, and enhancement for biosensing and imaging applications
• Explores the coverage of biocompatibility, toxicity concerns, environmental and safety considerations, and legal and commercialization aspects of 2D nanomaterials for biosensing and imaging applications.

Audience

Graduate, postgraduate, and engineering students, research scholars, and faculty working in materials science, biotechnology, biomedical engineering, biochemistry, and biophysics, as well as material engineers, scientists, and technologists in the electronic, electrical, and biomedical industries.

Leseprobe

Scrivener Publishing100 Cummings Center, Suite 541JBeverly, MA 01915-6106

Publishers at ScrivenerMartin Scrivener ([email protected])Phillip Carmical ([email protected])

Two-Dimensional Nanomaterials for Biosensing and Imaging Applications

Edited by

Ram Sevak Singh

Dept. of Physics, OP Jindal University, Raigarh, Chhattisgarh, India

Kalim Deshmukh

Chemical Processes and Biomaterials New Technologies Research Centre, University of West Bohemia, Plzeň, Czech Republic

and

Chaudhery Mustansar Hussain

Dept. of Chemistry and Environmental Science New Jersey Institute of Technology (NJIT), Newark, New Jersey, USA

This edition first published 2025 by John Wiley & Sons, Inc., 111 River Street, Hoboken, NJ 07030, USA and Scrivener Publishing LLC, 100 Cummings Center, Suite 541J, Beverly, MA 01915, USA© 2025 Scrivener Publishing LLCFor more information about Scrivener publications please visit www.scrivenerpublishing.com.

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Library of Congress Cataloging-in-Publication Data

ISBN 978-1-394-19992-1

Front cover image courtesy of Adobe FireflyCover design by Russell Richardson

Preface

Nanotechnology is pivotal in advancing biotechnology and medical science. Nanomaterials, essential components of this technology, showcase unique and superior physicochemical properties when compared to their bulk equivalents. The quantum confinement effect, coupled with an enhanced surface-to-volume ratio, renders these materials ideal for biosensing and bioimaging applications. Since the groundbreaking discovery of graphene in 2004, two-dimensional (2D) nanomaterials have garnered immense attention. Thanks to their remarkable properties, 2D materials are increasingly recognized for their potential across a wide array of applications, including energy, electronics, optoelectronics, fuel cells, memory storage, corrosion prevention, and the biotechnological and biomedical sectors.

This book, Two Dimensional Nanomaterials for Biosensing and Imaging Applications, offers an exhaustive exploration of the fundamental chemistry, physics, biology, and engineering of advanced 2D nanomaterials, catering to a global audience of researchers interested in the development of high-performance biosensors and bioimaging systems. The content comprehensively covers the historical context, intrinsic properties of 2D materials, and the detailed processes involved in the fabrication, processing, and structural design of biosensors and bioimaging devices used in cutting-edge applications within the biomedical and food industries.

Internationally acclaimed researchers contribute state-of-the-art reviews on the current status and recent advances in the fabrication, processing, and properties of various 2D materials apt for biosensing and imaging applications. The book is driven by the burgeoning interest among scholars from academic institutions, research institutes, and industries to delve into the current and emerging trends in the development and analysis of 2D materials, their composites, and heterostructures, with a focus on applications in the biosensing and healthcare sectors.

A unique aspect of this publication is its systematic scientific approach. While numerous articles have been published on 2D materials, this is the first comprehensive reference focusing specifically on their application in biosensing and imaging. It addresses a wide range of unresolved issues and new technical challenges related to the toxicology, biocompatibility, environmental, and health impacts of 2D nanomaterials in biosensing applications, making it a pivotal resource for advancing research in this dynamic field.

This book will prove invaluable for scientists, engineers, and students at the graduate and doctoral levels who are engaged in the fields of nanomaterials and technology, materials science and engineering, as well as biology, biochemistry, biophysics, biotechnology, composites, and nanocomposites. It offers insights and solutions for both fundamental and applied challenges in this research area. Furthermore, by compiling existing knowledge on the fundamentals, fabrication, processing, characterizations, and applications of 2D materials in biosensing across various research domains, this book serves as an essential resource for new researchers seeking to swiftly familiarize themselves with the field and address its key questions.

We want to express our deepest appreciation to all the contributors who have dedicated their time and efforts to making this book a success. Additionally, we extend our deepest thanks for the suggestions, help, and support from Martin Scrivener and the team at Scrivener Publishing.

Ram Sevak SinghKalim DeshmukhChaudhery Mustansar HussainApril 2025

2Electrical, Optical, and Electronic Properties of 2D Nanomaterials

Humira Assad1, Ishrat Fatma1, Richika Ganjoo1 and Ashish Kumar2*

1Department of Chemistry, School of Chemical Engineering and Physical Sciences, Lovely Professional University, Punjab, India

2Nalanda College of Engineering, Bihar Engineering University, Department of Science, Technology and Technical Education, Government of Bihar, India

Abstract

Nanotechnology, often known as the “Industrial Revolution” of the 21st century, is the technology with the fastest global growth rate. Numerous research, development, and production techniques have been applied globally to create better, safer nanomaterials with incredible properties for a variety of applications. Two-dimensional (2D) materials are a unique family of ultra-thin nanomaterials with just one layer of atoms. Due to their substantial surface area and the advancement of nanofabrication and characterization technology, 2D layered nanomaterials display captivating physicochemical characteristics that pique enthusiasm greatly and demonstrate a plethora of possible uses in nano-electronics, optoelectronics, energy storage, flexible devices, etc. The goal of this chapter is to highlight a few important attributes, such as electrical, optical, and electronic properties, that have emerged in the extensive and quickly expanding literature on 2D nanomaterials. Moreover, the potential and obstacles in this promising research field are also suggested.

Keywords: Nanotechnology, 2D nanomaterials, nanofabrication, electric, optical, electronic

List of Abbreviations

2D

Two-Dimensional

BG

Bandgap

BP

Black Phosphorus

BU

Bottom-Up

CNTs

Carbon Nanotubes

CVD

Chemical Vapor Deposition

GNFs

Graphene Nano-Flakes

GO

Graphene Oxide

hBN

Hexagonal Boron Nitride

LM

Layered Materials

NMs

Nanomaterials

NPs

Nanoparticles

NSs

Nanosheets

PNCs

Polymer Nanocomposites

rGO

Reduced Graphene Oxide

SAMs

Self-Assembled Monolayers

THG

Third-Harmonic Generation

TD

Top-Down

TMOs

Transition Metal Oxides

2D

Two-Dimensional

UL

Ultra Large

UT

Ultra-Thin

vdW

Van der Waals

2.1 Introduction

The manufacture of a broad array of substances, such as particulate materials having at least one dimension smaller than 100 nm, is made possible by the advanced field of research known as nanotechnology. Chemical compounds or substances that are produced and utilized at a very minor scale, i.e., 1–100 nm in at least one dimension, are known as nanomaterials (NMs) as shown in Figure 2.1.

Figure 2.1 Diagram illustrating the comparison of the size scale of objects with the regime of nanoscale size [1]. Copyright 2022.

Reproduced with permission from MDPI.

Particles larger than 100 nm in all directions are referred to be bulk materials. While distinct physical qualities can rely on the size and form of NMs, they can differ from bulk material, where physical attributes are size independent [2–4]. Researchers discovered that size affects a substance’s physicochemical qualities, such as its chemical, electrical, electronic, and optical characteristics. This discovery made it clear how important NMs are. Consequently, due to their distinct qualities, nano-particulate materials have garnered a lot of attention. Among the many uses for nanoparticles (NPs) are water purification facilities, petroleum refineries, industrial activities, catalytic processes, construction and building products, diagnostics, and drug delivery [5–7]. One approach to categorizing nanomaterials is based on their dimensions; the same chemical compounds might have remarkably varied characteristics based on whether they are categorized in a zero (0D), one (1D), two (2D), or three (3D) dimensional crystal framework. A small number of studies on 2D nanomaterials have been reported, despite the reality that there have been many published studies on 0D, 1D, and of course 3D. Owing to their thickness and macroscale/nanoscale dimensions, 2D NMs are thought to be the thinnest complexes [8–10