Stem-Cell Nanoengineering E-Book

H. Baharvand

• Herausgeber: John Wiley & Sons
• Kategorie: Wissenschaft und neue Technologien
• Sprache: Englisch

Seitenzahl: 953

Veröffentlichungsjahr: 2014

Beschreibung

Stem Cell Nanoengineering reviews the applications of nanotechnology in the fields of stem cells, tissue engineering, and regenerative medicine. Topics addressed include various types of stem cells, underlying principles of nanobiotechnology, the making of nano-scaffolds, nano tissue engineering, applications of nanotechnology in stem cell tracking and molecular imaging, nano-devices, as well as stem cell nano-engineering from bench to bedside.

Written by renowned experts in their respective fields, chapters describe and explore a wide variety of topics in stem cell nanoengineering, making the book a valuable resource for both researchers and clinicians in biomedical and bioengineering fields.

Leseprobe

CONTENTS

Cover

Title page

Copyright page

Dedication page

About the Editors

Contributors

Preface

Part 1: An Introduction to Stem Cells

Chapter 1: Adult Stem Cells

Introduction

Adult Stem Cells

Adult Stem-Cell Plasticity

Classification of Adult Stem Cells

Hematopoietic Stem Cells

Mesenchymal Stem Cells

Aging

Aging of ASCs and Possible Consequences

Stem Cells in Regenerative Medicine and

in vitro

Application

Summary

Acknowledgments

References

Chapter 2: Pluripotent Stem Cells

Introduction

Induced Pluripotent Stem Cells

Pluripotent Stem Cells from Germ Cells of the Testis

Regulation of PSCs

Application of Nanotechnology to PSCs

Conclusions

References

Chapter 3: Interactions of Stem Cells and Components of the Extracellular Matrix

Introduction

Chemical Properties of the ECM

Topographical Features of the ECM

Mechanical Properties of ECM

Perspective

References

Chapter 4: Regenerative Medicine and Cell Therapy: Past, Present, and Future

Introduction

Basics of Regenerative Medicine

Cell Types Used in Regenerative Medicine

Extracellular Matrix

In Vivo

: Components and Behavior of Cells on Them

Regenerative Medicine and Cell Therapy: Past, Present, and Future

Summary and Conclusion

Acknowledgment

References

Part 2: An Introduction to Nanotechnology

Chapter 5: Principles of Nanotechnology

Introduction

General Characteristics of Nanomaterials

Nanotechnology

Classification of Nanomaterials

Environmental and Health Effects of Nanomaterials

Conclusions

Acknowledgments

References

Chapter 6: Stem-Cell Nanoengineering: Explorations in a Rapidly Moving Field

Introduction

Need for Stem-Cell Nanoengineering

Nanoengineering to Study Stem-Cell Niche

Nanoengineering to Study Stem-Cell Homing

Nanoscale Approaches to Elucidate Stem-Cell and ECM Interaction

Nanoengineering Approaches to Study Stem-Cell Fate

Conclusions and Future Prospective

Acknowledgments

References

Part 3: Nanostructures for Stem-Cell Engineering – Engineering Approach

Chapter 7: Nanopatterned Surfaces for Stem-Cell Engineering

Introduction

Technology for Nanopatterned Surface of Cell Chips

Application of Nanopatterned Surface to Stem-Cell-Based Chips

Conclusions, Challenges, and Future Perspectives

Acknowledgments

References

Chapter 8: Biomimetic Nanostructures by Electrospinning and Electrospraying

Introduction

Biomimetic Nanofibrous Scaffolds

Nanofiber Fabrication Techniques

The Effect of Nanofibrous Scaffold Parameters on Stem-Cell Behavior

Regulation of Electrospun Nanofibers

Bioelectrospraying and Cell-Electrospinning

Conclusions

Acknowledgements

References

Chapter 9: Nanoparticles for Stem-Cell Engineering

Introduction

Nanoparticle Toxicity to Stem Cells

Nanoparticles for Detecting Stem Cells

Nanoparticles for Growth Factor Delivery to Stem Cells

Nanoparticles for Gene Delivery to Stem Cells

Nanoparticles for Patterning Stem Cells

Conclusion

Acknowledgments

References

Chapter 10: Toxicology of Nanobiomaterials

Introduction