Biomaterials from Nature for Advanced Devices and Therapies E-Book
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- Herausgeber: John Wiley & Sons
- Kategorie: Fachliteratur
- Serie: Wiley-Society for Biomaterials
- Sprache: Englisch
In-depth information on natural biomaterials and their applications for translational medicine!
- Undiluted expertise: edited by world-leading experts with contributions from top-notch international scientists, collating experience and cutting-edge knowledge on natural biomaterials from all over the world
- A must-have on the shelf in every biomaterials lab: graduate and PhD students beginning their career in biomaterials science and experienced researchers and practitioners alike will turn to this comprehensive reference in their daily work
- Link to clinical practice: chapters on translational research make readers aware of what needs to be considered when a biomaterial leaves the lab to be routinely used
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Biomaterials from Nature for Advanced Devices and Therapies
Edited by
NUNO M. NEVES
University of Minho
RUI L. REIS
University of Minho
Copyright © 2016 by John Wiley & Sons, Inc. All rights reserved.
Published by John Wiley & Sons, Inc., Hoboken, New Jersey. Published simultaneously in Canada.
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Library of Congress Cataloging-in-Publication Data
Names: Neves, Nuno M., editor. | Reis, Rui L., editor. Title: Biomaterials from nature for advanced devices and therapies / edited by Nuno Neves, Rui L Reis. Description: Hoboken, New Jersey : John Wiley & Sons, Inc., [2016] | Includes index. Identifiers: LCCN 2016017315 | ISBN 9781118478059 (cloth) | ISBN 9781119178071 (epub) Subjects: LCSH: Biomedical materials–Therapeutic use. Classification: LCC R857.M3 B5726 2016 | DDC 610.28/4–dc23 LC record available at https://lccn.loc.gov/2016017315
CONTENTS
Contributors
Preface
Part I
Chapter 1: Collagen-Based Porous Scaffolds for Tissue Engineering
1.1 Introduction
1.2 Collagen Sponges
1.3 Collagen Sponges with Micropatterned Pore Structures
1.4 Collagen Sponges with Controlled Bulk Structures
1.5 Hybrid Scaffolds
1.6 Conclusions
References
Chapter 2: Marine Collagen Isolation and Processing Envisaging Biomedical Applications
2.1 Introduction
2.2 Extraction of Collagen From Marine Sources
2.3 Collagen Characterization
2.4 Marine Collagen Wide Applications
2.5 Final Remarks
Acknowledgements
References
Chapter 3: Gelatin-Based Biomaterials For Tissue Engineering And Stem Cell Bioengineering
3.1 Introduction
3.2 Crosslinking of Gelatin
3.3 Physical Properties of Gelatin
3.4 Application of Gelatin-Based Biomaterials In Tissue Engineering
3.5 Gelatin for Stem Cell Therapy
3.6 Application of Gelatin In Delivery Systems
3.7 Conclusion and Perspectives
Acknowledgements
Abbreviations
References
Chapter 4: Hyaluronic Acid-Based Hydrogels on a Micro and Macro Scale
4.1 Classification and Structure of Hydrogels
4.2 Hyaluronic Acid
4.3 Hydrogel Mechanical Properties
4.4 HA-Based Hydrogel for Biomedical Applications
References
Chapter 5: Chondroitin Sulfate as a Bioactive Macromolecule for Advanced Biological Applications and Therapies
5.1 CS Structure
5.2 Biological Roles of CS
5.3 Osteoarthritis Treatment
5.4 Cardio-Cerebrovascular Disease
5.5 Tissue Regeneration and Engineering
5.6 Chondroitin Sulfate-Polymer Conjugates
5.7 Conclusions and Future Perspectives
References
Chapter 6: Keratin
6.1 Introduction
6.2 Preparation of Keratoses
6.3 Preparation of Kerateines
6.4 Oxidative Sulfitolysis
6.5 Summary
References
Chapter 7: Elastin-Like Polypeptides: Bio-Inspired Smart Polymers for Protein Purification, Drug Delivery and Tissue Engineering
7.1 Introduction
7.2 Recombinant Protein Production Using ELPs as Purification Tags
7.3 Delivery of Therapeutics with ELPs
7.4 Tissue Engineering with ELPs
7.5 Conclusions
Acknowledgements
Abbreviations
References
Chapter 8: Silk: A Unique Family of Biopolymers
8.1 Introduction
8.2 Main Silk Polymers
8.3 Fibroin Basic Processing: Regenerated Silk Fibroin
8.4 Materials Fabrication of Silk Proteins
8.5 Advanced Material Applications of Silks
8.6 Conclusion
References
Chapter 9: Silk Protein Sericin: Promising Biopolymer for Biological and Biomedical Applications
9.1 Introduction
9.2 Sericin Extraction and Processing
9.3 Potential Applications Of Sericin
9.4 Immunogenicity and Toxicity Of Sericin
9.5 Conclusion
Acknowledgements
References
Chapter 10: Fibrin
10.1 Introduction
10.2 Fibrin Clotting
10.3 Fibrin Degradation
10.4 Fibrin Glue
10.5 Conclusion
Acknowledgement
References
Chapter 11: Casein Proteins
11.1 Introduction
11.2 Structures and Properties of Casein
11.3 Interaction of Caseins with Metal Ions
11.4 Conclusions
References
Chapter 12: Biomaterials from Decellularized Tissues
12.1 Introduction
12.2 Host Response to Implanted ECM-Derived Biomaterials
References
Chapter 13: Demineralized Bone Matrix: A Morphogenetic Extracellular Matrix
13.1 Introduction
13.2 Demineralized Bone Matrix (DBM)
13.3 From DBM to Bone Morphogenetic Proteins (BMPs)
13.4 BMPs bind To Extracellular Matrix
13.5 BMP Receptors
13.6 Future Perspectives
Acknowledgements
References
Part II
Chapter 14: Recent Developments on Chitosan Applications in Regenerative Medicine
14.1 Introduction
14.2 Chitosan and Derivatives
14.3 Regenerative Medicine Applications of Chitosan
14.4 Processing Methodologies
14.5 Final Remarks
14.6 Acknowledgments
References
Chapter 15: Starch-Based Blends in Tissue Engineering
15.1 Introduction
15.2 Starch
15.3 Modification of Starch for Biomedical Applications
15.4 Starch-Based Blends
15.5 Conclusions and Future Perspectives
References
Chapter 16: Agarose Hydrogel Characterization for Regenerative Medicine Applications: Focus on Engineering Cartilage
16.1 The Foundations of Agarose
16.2 Structure-Function Relationships of Agarose Hydrogels
16.3 Agarose as a Tissue Engineering Scaffold
16.4 Agarose In The Clinic
16.5 A Scaffold To Build On
Acknowledgements
References
Chapter 17: Bioengineering Alginate for Regenerative Medicine Applications
17.1 Introduction
17.2 Regenerative Medicine: Definition and Strategies
17.3 Alginate Biomaterial
17.4 Alginate Implant: First in Man Trial for Prevention of Heart Failure
17.5 Alginate Hydrogel as a Vehicle for Stem Cell Delivery and Retention
17.6 Engineering Alginate-Based Cell Microenvironments
17.7 Alginate Hydrogel Carrier for Growth Factor Delivery
17.8 Engineering Alginate For Affinity Binding And Presentation Of Heparin-Binding Growth Factors
References
Chapter 18: Dextran
18.1 Introduction
18.2 Structure and Properties
18.3 Dextran Derivatives
18.4 Dextran Copolymers
18.5 Degradation
18.6 Outlook
References
Chapter 19: Gellan Gum-based Hydrogels for Tissue Engineering Applications
19.1 Introduction
19.2 Gellan Gum and its Derivatives
19.3 Tissue Engineering Applications
19.4 Final Remarks
19.5 Acknowledgments
References
Part III
Chapter 20: Biomedical Applications of Polyhydroxyalkanoates
20.1 Introduction
20.2 Skin Tissue Engineering
20.3 Nerve Tissue Engineering
20.4 Cardiac Tissue Engineering
20.5 Dental Tissue Engineering
20.6 Bone Tissue Engineering
20.7 Cartilage Tissue Engineering
20.8 Osteochondral Tissue Engineering
20.9 Drug Delivery
20.10 Conclusions and the Future Potential of PHAs in Biomedical Applications
References
Chapter 21: Bacterial Cellulose
21.1 Introduction
21.2 BC Dressings
21.3 Bacterial Cellulose for Tissue Engineering and Regenerative Medicine
21.4 Concluding Remarks
Acknowledgments
References
Part IV
Chapter 22: Molecularly Imprinted Cryogels for Protein Purification
22.1 Introduction
22.2 Molecularly Imprinted Cryogels for Protein Purification
22.3 Some Selected Applications of Molecularly Imprinted Cryogels (MIC) for Macromolecules
22.4 Concluding Remarks And Future Perspectives
References
Chapter 23: Immunogenic Reaction of Implanted Biomaterials from Nature
23.1 Introduction
23.2 Implantation Leads to Tissue Injury
23.3 Inflammatory Responses
23.4 Foreign Body Reaction
23.5 Immunogenic Reactions Towards Natural Biomaterials
23.6 Final Remarks
References
Chapter 24: Chemical Modification of Biomaterials from Nature
24.1 Protein Modification
24.2 Lipid Modifications
24.3 Polysaccharide Chemical Modifications
References
Part V
Chapter 25: Processing of Biomedical Devices for Tissue Engineering and Regenerative Medicine Applications
25.1 Introduction
25.2 Processing Techniques of Naturally Derived Biomaterial
25.3 Processing Techniques of Natural-Based Polymeric Blends
References
Chapter 26: General Characterization of Physical Properties of Natural-Based Biomaterials
26.1 Introduction
26.2 Bulk Properties
26.3 Surface Properties
26.4 Concluding Remarks
Acknowledgments
References
Chapter 27: General Characterization of Chemical Properties of Natural-Based Biomaterials
27.1 Introduction
27.2 Molecular Weight and Elemental Composition
27.3 Physiological Degradation
27.4 Concluding Remarks
Acknowledgments
References
Chapter 28:
IN VITRO
Biological Testing in the Development of New Devices
28.1 Introduction
28.2 Cytotoxicity Assays
28.3 Evaluation of Cell Morphology and Distribution
28.4 Cell Viability Assays
28.5 Cell Proliferation Assays
28.6 Biochemical Analysis
28.7 Genotypic Expression Analysis
28.8 Histological Assessment
28.9
IN VITRO
Engineered Tissues
28.10 Concluding Remarks
References
Chapter 29: Advanced
IN-VITRO
Cell Culture Methods Using Natural Biomaterials
29.1 Introduction
29.2 Bioreactors
29.3 Hypoxia
29.4 Co-Cultures
29.5 Transfection
29.6 Nanoparticles and Related Systems
29.7 Concluding Remarks
References
Chapter 30: Testing Natural Biomaterials in Animal Models
30.1 Laboratory Animals as Tools in Biomaterials Testing
30.2 Inflammation and Host Reaction
30.3 Animal Models for Tissue Engineering
30.4 Final Remarks
References
Part VI
Chapter 31: Delivery Systems Made of Natural-Origin Polymers for Tissue Engineering and Regenerative Medicine Applications
31.1 Introduction
31.2 Advantages and Disadvantages of Natural Polymers-Based Delivery Systems
31.3 Fundamentals of Drug Delivery
31.4
IN VITRO
and
IN VIVO
Applications of Natural-Based Delivery Systems
31.5 Concluding Remarks
References
Chapter 32: Translational Research Into New Clinical Applications
32.1 Introduction
32.2 Cardiovascular System Applications
32.3 Integumentary System Applications
32.4 Musculoskeletal System Applications
32.5 Nervous System Applications
32.6 Respiratory System Applications
32.7 Gastrointestinal System Applications
32.8 From Idea to Product
Acknowledgements
References
Chapter 33: Challenges and Opportunities of Natural Biomaterials for Advanced Devices and Therapies
33.1 Introduction
33.2 Challenges of Natural Biomaterials
33.3 Opportunities of Natural Biomaterials
33.4 Final Remarks
References
Chapter 34: Adhesives Inspired by Marine Mussels
34.1 Introduction
34.2 Requirements for a Bioadhesive
34.3 Marine Mussels
34.4 Bulk Adhesion Testing
34.5 Extracted Mussel Adhesive Proteins
34.6 Mimics of Mussel Adhesive
34.7 Conclusions
Acknowledgement
References
Chapter 35: Final Comments and Remarks
Index
EULA
List of Tables
Chapter 2
Table 2.1
Chapter 4
Table 4.1
Chapter 7
Table 7.1
Chapter 8
Table 8.1
Chapter 9
Table 9.1
Chapter 11
Table 11.1
Table 11.2
Chapter 12
Table 12.1
Table 12.2
Chapter 15
Table 15.1
Chapter 20
Table 20.1
Table 20.2
Table 20.3
Table 20.4
Table 20.5
Table 20.6
Chapter 27
Table 27.1
Chapter 29
Table 29.1
Chapter 30
Table 30.1
Chapter 31
Table 31.1
Chapter 32
Table 32.1
Guide
Cover
Table of Contents
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