Cancer Consult E-Book

• Herausgeber: John Wiley & Sons
• Kategorie: Fachliteratur
• Sprache: Englisch

Seitenzahl: 2770

Veröffentlichungsjahr: 2014

Beschreibung

The field of oncology benefits from several large-scale reference books and a host of monographs dedicated to specific cancers. However, truly excellent practice and review books are, surprisingly, quite scarce. Outside of a scant handful of books and online reference tools that offer clinical response practice and board review in a basic question and answer format, there are no resources that offer a robust, engaging, fully referenced tool for these vital activities in every oncologist’s and oncology trainee’s work. This print and electronic book seeks to fill that void, offering comprehensive question-and-answer style content that covers the entire specialty of oncology and provides practicing oncologists with a fascinating and immediately applicable compendium of vital information dealing with a well-balanced selection of common and uncommon cancers. At the heart of this book is the editor’s and authors’ desire to overcome the controversies and barriers to practice that usually emerge following the appearance of new data. In every section, the user is guided toward collaboration in ongoing clinical research – for example, via discussions of well-designed ongoing clinical trials in each specific area.

Developed with both the teacher and learner in mind, this book also offers trainees and fellows an excellent opportunity to enhance their preparation for the ABIM oncology fellowship exam as well as for the oncology boards. It will also be an extremely useful tool for oncologists working toward the recertification exam. This comprehensive, beefy book includes hundreds of painstakingly developed multiple-choice and mini-case-based questions covering the principles of medical oncology, malignant hematology, surgical oncology, and radiation oncology. It also contains mini-cases and questions dealing with the biology, diagnosis, classification, staging, and multidisciplinary treatment of cancers at every anatomic site. The very latest topics are included, such as molecular techniques, targeted therapies, and translational cancer research. Concise but detailed answers are referenced to key journals and books, and evidence-based wherever possible. NCCN guidelines are also referenced as appropriate. With its powerful focus on take-home messages from and for actual clinical work, this book will help keep oncologists up to date, bridging the gaps between journal and reference literature, conferences, and their existing knowledge base.

Leseprobe

Table of Contents

Dedication

Title page

Copyright page

List of Contributors

Preface

SECTION 1: Malignant Hematology and Hematopoietic Cell Transplantation

PART 1: Acute Lymphoblastic Leukemia in Adults

CHAPTER 1: Diagnosis of Acute Lymphoblastic Leukemia

Case Study Answers

Selected Readings

CHAPTER 2: Prognostic Markers and Models in Acute Lymphoblastic Leukemia

Pretherapeutic Prognostic Markers

Response Parameters

Stratification into Risk Groups

Selected Reading

CHAPTER 3: Management of B-Cell Acute Lymphoblastic Leukemia

Selected Reading

CHAPTER 4: Management of T-Cell Acute Lymphoblastic Leukemia

Selected Reading

CHAPTER 5: Minimal Residual Disease in Acute Lymphoblastic Leukemia

Case Study Answers

Selected Reading

CHAPTER 6: Hematopoietic Cell Transplantation in Adult Acute Lymphoblastic Leukemia

Multiple Choice and Discussion Questions

Mutiple Choice Answer

Case Study Answer

Selected Reading

PART 2: Acute Myeloid Leukemia in Adults

CHAPTER 7: Prognosis in Acute Myeloid Leukemia: Cytogenetics and Beyond

Case Study Answers

Selected Reading

CHAPTER 8: Induction Therapy in Acute Myeloid Leukemia

Case Study Answers

Selected Reading

CHAPTER 9: Consolidation Therapy in Acute Myeloid Leukemia

Selected Reading

CHAPTER 10: Management of Acute Promyelocytic Leukemia

Selected Reading

CHAPTER 11: Minimal Residual Disease in Acute Myeloid Leukemia

Selected Reading

CHAPTER 12: Relapsed and Refractory Acute Myeloid Leukemia

Multiple Choice Questions

Case Study Answers

Mutiple Choise Answers

Selected Reading

CHAPTER 13: Hematopoietic Cell Transplantation in Acute Myeloid Leukemia

Multiple choice question

Case Study Answers

Mutiple choice answer

Selected reading

PART 3: Myelodysplastic Syndromes and Related Disorders

CHAPTER 14: Pitfalls in the Diagnosis of Myelodysplastic Syndromes

Case Study Answers

Selected Reading

CHAPTER 15: Cytogenetics and Prognostic Models in Myelodysplastic Syndromes

MDS Cytogenetics and Prognosis

Conclusion

Selected Reading

CHAPTER 16: Management of Myelodysplastic Syndromes

Selected Reading

CHAPTER 17: Management of Therapy-Related Myeloid Neoplasms

Introduction

Multiple Choice Questions

Multiple Choice Answers

Note

Selected Reading

CHAPTER 18: Hematopoietic Cell Transplantation in Myelodysplastic Syndromes

Notes

Selected Reading

CHAPTER 19: Acquired Aplastic Anemia

Case Study Answers

Selected Reading

PART 4: Myeloproliferative Neoplasms

CHAPTER 20: Diagnostic Approach in Myeloproliferative Neoplasms

Introduction

Selected Reading

CHAPTER 21: Chronic Myeloid Leukemia: Chronic Phase

Introduction

Multiple Choice and Discussion Questions

Multiple Choice Answer

Selected Reading

Selected Websites

CHAPTER 22: Blast Crisis of Chronic Myeloid Leukemia

Selected Reading

CHAPTER 23: Chronic Myeloid Leukemia and Pregnancy

Selected Reading

CHAPTER 24: Polycythemia Vera

Selected Reading

CHAPTER 25: Essential Thrombocytosis

Case Study Answers

Note

Selected Reading

CHAPTER 26: Primary Myelofibrosis

Introduction

Selected Reading

CHAPTER 27: Eosinophilic Myeloproliferative Disorders

Case Study Answers

Selected Reading

CHAPTER 28: Chronic Myelomonocytic Leukemia

Selected Reading

CHAPTER 29: Hematopoietic Cell Transplantation in Chronic Myeloid Leukemia

Case Study Answers

Selected Reading

CHAPTER 30: Hematopoietic Cell Transplantation in Primary Myelofibrosis

Conclusion

Selected Reading

PART 5: Chronic Lymphocytic and Other Leukemias

CHAPTER 31: Prognostic Markers and Management of Chronic Lymphocytic Leukemia

Multiple Choice Questions

Multiple Choice Answers

Selected reading

CHAPTER 32: Hematopoietic Cell Transplantation in Chronic Lymphocytic Leukemia

Selected Reading

CHAPTER 33: Prolymphocytic Leukemia

Summary

Case Study Answers

Selected Reading

CHAPTER 34: Hairy Cell Leukemia

Multiple Choice and Discussion Questions

Selected Reading

Case Study Answers

Multiple Choice Answer

PART 6: Hodgkin Lymphoma

CHAPTER 35: Management of Classical Hodgkin Lymphoma

Case Study Answers

Selected Reading

CHAPTER 36: Nodular Lymphocyte-Predominant Hodgkin Lymphoma

Multiple Choice Questions

Multiple Choice Answers

Seleced Reading

CHAPTER 37: Hematopoietic Cell Transplantation in Hodgkin Lymphoma

Selected Reading

PART 7: Non-Hodgkin's Lymphomas

CHAPTER 38: Pitfalls in the Diagnosis of Non-Hodgkin's Lymphomas

Case Study Answers

Selected Reading

CHAPTER 39: Follicular Lymphoma

Case Study Answers

Selected Reading

CHAPTER 40: Diffuse Large B-Cell Lymphoma

Introduction

Multiple Choice and Discussion Questions

Conclusion

Multiple Choice Answers

Selected Reading

CHAPTER 41: Mantle Cell Lymphoma

Case Study Answers

Selected Reading

CHAPTER 42: Marginal Zone Lymphoma

Treatment Controversies

Selected Reading

CHAPTER 43: Primary Mediastinal Large B-Cell Lymphoma

Clinical Features

Primary Management

Selected reading

CHAPTER 44: Burkitt Lymphoma

Selected Reading

CHAPTER 45: Gray Zone Lymphoma

Selected Reading

CHAPTER 46: Transformed Lymphoma

Multiple Choice Question

Multiple Choice Question

Case Study Answers

Multiple Choice Answers

Selected Reading

CHAPTER 47: HIV-Associated Lymphoma

Selected Reading

CHAPTER 48: Primary CNS Lymphoma

Case Study Answers

Selected Reading

CHAPTER 49: Primary Cutaneous Lymphoma

Introduction

Topical Approaches

Ultraviolet B Phototherapy and Ultraviolet A Photochemotherapy

Total Skin Electron Beam Therapy

Treatment of Advanced-Stage Disease

Extracorporeal Photochemotherapy

Recombinant Interferon

Bexarotene

Denileukin Difitox

Histone Deacetylase (HDAC) Inhibitors

Purine Nucleoside Analogs

Pegylated Liposomal Doxorubicin

Pralatrexate

Monoclonal Antibodies

Combined-Modality Systemic Chemotherapy

High-Dose Chemotherapy and Hematopoietic Stem Cell Transplantation

Treatment Summary

Survivorship Issues in Cutaneous T-Cell Lymphoma

Conclusion

Suggested Reading

CHAPTER 50: Mycosis Fungoides and Sézary Syndrome

Selected Reading

CHAPTER 51: Hematopoietic Cell Transplantation in Indolent Non-Hodgkin's Lymphoma

Selected Reading

CHAPTER 52: Hematopoietic Cell Transplantation in Diffuse Large B-cell Lymphoma

Case Study Answers

Selected Reading

CHAPTER 53: Hematopoietic Cell Transplantation in T-Cell Non-Hodgkin's Lymphomas

Introduction

Summary

Selected Reading

PART 8: Plasma Cell Neoplasms and Related Disorders

CHAPTER 54: Smoldering Multiple Myeloma and Monoclonal Gammopathy of Undetermined Significance

Mutiple Choice and Discussion Questions

Smoldering (Asymptomatic) Multiple Myeloma (SMM)

Mutiple Choice Answers

Selected Reading

CHAPTER 55: Risk Stratification and Response Assessment in Multiple Myeloma and Waldenström's Macroglobulinemia

Case Study Answers

Selected Reading

CHAPTER 56: Treatment of Multiple Myeloma

Prognostic Markers

Mutiple Choice Questions

Front-Line Therapy in Symptomatic Multiple Myeloma

Treatment Strategies

Case Study Answers

Mutiple Choice Ansewrs

Selected Reading

CHAPTER 57: Light-Chain Amyloidosis

Case Study Answers

Selected Reading

CHAPTER 58: Waldenström's Macroglobulinemia

Mutiple Choice and Discussion Questions

Cryoglobulinemia and Related Autoimmune Disorders in WM

Risk of Amyloid Light-Chain (AL) Amyloidosis

IgM-Related Neurologic Manifestations

Survivorship Issues in W4M

Mutiple Choice Answer

Case Study Answers

Selected Reading

CHAPTER 59: Autologous Hematopoietic Cell Transplantation in Multiple Myeloma

Selected Reading

CHAPTER 60: Allogeneic Hematopoietic Cell Transplantation in Multiple Myeloma

Introduction

The Evolution of the Allogeneic Approach in MM

Randomized Trials

Lenalidomide

Bortezomib

Measuring the Efficacy of Allo-HCT and Defining Deeper Remissions After Allo-HCT

The Future of Allo-HCT for MM

Selected Reading

PART 9: Special Issues in Hematology

CHAPTER 61: Role of PET Scan in Lymphomas

Mutiple Choice Questions

Case Study Answers

Multiple Choice Answers

Selected Reading

CHAPTER 62: Radioimmunotherapy in Lymphomas

Multiple Choice Questions

Mutiple Choice Answers

Selected Reading

CHAPTER 63: Radiation Oncology Consultation for Hematologic Malignancies

Selected Reading

PART 10: Special Issues in Hematopoietic Cell Transplantation

CHAPTER 64: Donor and Graft Selection in Allogeneic Hematopoietic Cell Transplantation

Introduction

Case Study Answers

Selected Reading

CHAPTER 65: Preparative Regimens in Allogeneic Hematopoietic Cell Transplantation for Malignant Hematological Diseases

Multiple Choice Questions

Multiple Choice Answers

Selected Reading