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Beschreibung

Clinical Guide to Paediatrics enables rapid reference to the common paediatric conditions, symptoms, and practical concerns seen in day-to-day practice. Focused on making differential diagnoses in acute settings, this comprehensive resource offers step-by-step guidance on clinical decision-making, investigations, and interventions. Junior doctors and medical students are provided with a clear and up-to-date evidence base supported by numerous diagnostic algorithms, diagrams, tables and bullet points throughout.

Organised into systems-based sections, the guide covers paediatric history taking, examination techniques, pharmacology, safeguarding, and a range of different diagnoses for presenting complaints in cardiology, infection and immunology, neurology, gastroenterology, accidents, poisoning, and more. Succinct chapters are logically structured to allow easy access to important concepts, key clinical details, and plans of investigation. Designed to complement the doctor-patient interaction in clinical practice, this valuable guide:

  • Covers the most common presenting complaints encountered in acute paediatrics
  • Provides evidence-based information on symptoms, disorders, and issues faced in paediatric medicine
  • Addresses topics from the perspective of presenting complaints to provide a unique, highly practical approach to the subject
  • Includes access to a companion website containing images and clinical photos, audio podcasts, clinical case studies, and self-assessment exercises

Clinical Guide to Paediatrics is essential reading for junior doctors, medical students, nurses and specialist trainees working on paediatric wards or emergency departments.

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Table of Contents

Cover

Series Page

Title Page

Copyright Page

List of Contributors

Acronyms and Abbreviations

About the Companion Website

How to Use This Book

1.1 Wheeze

1.1.1 CHAPTER AT A GLANCE

1.1.2 DEFINITION

1.1.3 DIAGNOSTIC ALGORITHM

1.1.4 DIFFERENTIALS LIST

1.1.5 KEY HISTORY FEATURES

1.1.6 KEY EXAMINATION FEATURES

1.1.7 KEY INVESTIGATIONS

1.1.8 KEY MANAGEMENT PRINCIPLES

1.2 Stridor

1.2.1 CHAPTER AT A GLANCE

1.2.2 DEFINITION

1.2.3 DIAGNOSTIC ALGORITHM

1.2.4 DIFFERENTIALS LIST

1.2.5 KEY HISTORY FEATURES

1.2.6 KEY EXAMINATION FEATURES

1.2.7 KEY INVESTIGATIONS

1.2.8 KEY MANAGEMENT PRINCIPLES

1.3 Difficulty in Breathing

1.3.1 CHAPTER AT A GLANCE

1.3.2 DEFINITION

1.3.3 DIAGNOSTIC ALGORITHM

1.3.4 DIFFERENTIALS LIST

1.3.5 KEY HISTORY FEATURES

1.3.6 KEY EXAMINATION FEATURES

1.3.7 KEY INVESTIGATIONS

1.3.8 KEY MANAGEMENT PRINCIPLES

2.1 Cyanosis

2.1.1 CHAPTER AT A GLANCE

2.1.2 DEFINITION

2.1.3 DIAGNOSTIC ALGORITHM

2.1.4 DIFFERENTIALS LIST

2.1.5 KEY HISTORY FEATURES

2.1.6 KEY EXAMINATION FEATURES

2.1.7 KEY INVESTIGATIONS

2.1.8 KEY MANAGEMENT PRINCIPLES

2.2 Circulatory Collapse

2.2.1 CHAPTER AT A GLANCE

2.2.2 DEFINITION

2.2.3 DIAGNOSTIC ALGORITHM

2.2.4 DIFFERENTIALS LIST

2.2.5 KEY HISTORY FEATURES

2.2.6 KEY EXAMINATION FEATURES

2.2.7 KEY INVESTIGATIONS

2.2.8 KEY MANAGEMENT PRINCIPLES

2.3 Syncope

2.3.1 CHAPTER AT A GLANCE

2.3.2 DEFINITION

2.3.3 DIAGNOSTIC ALGORITHM

2.3.4 DIFFERENTIALS LIST

2.3.5 KEY HISTORY FEATURES

2.3.6 KEY EXAMINATION FEATURES

2.3.7 KEY INVESTIGATIONS

2.3.8 KEY MANAGEMENT PRINCIPLES

2.4 Chest Pain

2.4.1 CHAPTER AT A GLANCE

2.4.2 DEFINITION

2.4.3 DIAGNOSTIC ALGORITHM

2.4.4 DIFFERENTIALS LIST

2.4.5 KEY HISTORY FEATURES

2.4.6 KEY EXAMINATION FEATURES

2.4.7 KEY INVESTIGATIONS

2.4.8 KEY MANAGEMENT PRINCIPLES

2.5 Palpitations

2.5.1 CHAPTER AT A GLANCE

2.5.2 DEFINITION

2.5.3 DIAGNOSTIC ALGORITHM

2.5.4 DIFFERENTIALS LIST

2.5.5 KEY HISTORY FEATURES

2.5.6 KEY EXAMINATION FEATURES

2.5.7 KEY INVESTIGATIONS

2.5.8 KEY MANAGEMENT PRINCIPLES

3.1 Fever

3.1.1 CHAPTER AT A GLANCE

3.1.2 DEFINITION

3.1.3 DIAGNOSTIC ALGORITHM

3.1.4 DIFFERENTIALS LIST

3.1.5 KEY HISTORY FEATURES

3.1.6 KEY EXAMINATION FEATURES

3.1.7 KEY INVESTIGATIONS

3.1.8 KEY MANAGEMENT PRINCIPLES

3.2 Fever in the Returning Traveller

3.2.1 CHAPTER AT A GLANCE

3.2.2 DEFINITION

3.2.3 DIAGNOSTIC ALGORITHM

3.2.4 DIFFERENTIALS LIST

3.2.5 KEY HISTORY FEATURES

3.2.6 KEY EXAMINATION FEATURES

3.2.7 KEY INVESTIGATIONS

3.2.8 KEY MANAGEMENT PRINCIPLES

3.3 Lymphadenopathy

3.3.1 CHAPTER AT A GLANCE

3.3.2 DEFINITION

3.3.3 DIAGNOSTIC ALGORITHM

3.3.4 DIFFERENTIALS LIST

3.3.5 KEY HISTORY FEATURES

3.3.6 KEY EXAMINATION FEATURES

3.3.7 KEY INVESTIGATIONS

3.3.8 KEY MANAGEMENT PRINCIPLES

4.1 Bruising

4.1.1 CHAPTER AT A GLANCE

4.1.2 DEFINITION

4.1.3 DIAGNOSTIC ALGORITHM

4.1.4 DIFFERENTIALS LIST

4.1.5 KEY HISTORY FEATURES

4.1.6 KEY EXAMINATION FEATURES

4.1.7 KEY INVESTIGATIONS

4.1.8 KEY MANAGEMENT PRINCIPLES

4.2 Pallor

4.2.1 CHAPTER AT A GLANCE

4.2.2 DEFINITION

4.2.3 DIAGNOSTIC ALGORITHM

4.2.4 DIFFERENTIALS LIST

4.2.5 KEY HISTORY FEATURES

4.2.6 KEY EXAMINATION FEATURES

4.2.7 KEY INVESTIGATIONS

4.2.8 KEY MANAGEMENT PRINCIPLES

5.1 Abdominal Pain

5.1.1 CHAPTER AT A GLANCE

5.1.2 DEFINITION

5.1.3 DIAGNOSTIC ALGORITHM

5.1.4 DIFFERENTIALS LIST

5.1.5 KEY HISTORY FEATURES

5.1.6 KEY EXAMINATION FEATURES

5.1.7 KEY INVESTIGATIONS

5.1.8 KEY MANAGEMENT PRINCIPLES

5.2 Abdominal Mass

5.2.1 CHAPTER AT A GLANCE

5.2.2 DEFINITION

5.2.3 DIAGNOSTIC ALGORITHM

5.2.4 DIFFERENTIALS LIST

5.2.5 KEY HISTORY FEATURES

5.2.6 KEY EXAMINATION FEATURES

5.2.7 KEY INVESTIGATIONS

5.2.8 KEY MANAGEMENT PRINCIPLES

5.3 Vomiting

5.3.1 CHAPTER AT A GLANCE

5.3.2 DEFINITION

5.3.3 DIAGNOSTIC ALGORITHM

5.3.4 DIFFERENTIALS LIST

5.3.5 KEY HISTORY FEATURES

5.3.6 KEY EXAMINATION FEATURES

5.3.7 KEY INVESTIGATIONS

5.3.8 KEY MANAGEMENT PRINCIPLES

5.4 Diarrhoea

5.4.1 CHAPTER AT A GLANCE

5.4.2 DEFINITION

5.4.3 DIAGNOSTIC ALGORITHM

5.4.4 DIFFERENTIALS LIST

5.4.5 KEY HISTORY FEATURES

5.4.6 KEY EXAMINATION FEATURES

5.4.7 KEY INVESTIGATIONS

5.4.8 KEY MANAGEMENT PRINCIPLES

5.5 Jaundice

5.5.1 CHAPTER AT A GLANCE

5.5.2 DEFINITION

5.5.3 DIAGNOSTIC ALGORITHM

5.5.4 DIFFERENTIALS LIST

5.5.5 KEY HISTORY FEATURES

5.5.6 KEY EXAMINATION FEATURES

5.5.7 KEY INVESTIGATIONS

5.5.8 KEY MANAGEMENT PRINCIPLES

5.6 Faltering Growth

5.6.1 CHAPTER AT A GLANCE

5.6.2 DEFINITION

5.6.3 DIAGNOSTIC ALGORITHM

5.6.4 DIFFERENTIALS LIST

5.6.5 KEY HISTORY FEATURES

5.6.6 KEY EXAMINATION FEATURES

5.6.7 KEY INVESTIGATIONS

5.6.8 Key Management Principles

6.1 Haematuria

6.1.1 CHAPTER AT A GLANCE

6.1.2 DEFINITION

6.1.3 DIAGNOSTIC ALGORITHM

6.1.4 DIFFERENTIALS LIST

6.1.5 KEY HISTORY FEATURES

6.1.6 KEY EXAMINATION FEATURES

6.1.7 KEY INVESTIGATIONS

6.1.8 KEY MANAGEMENT PRINCIPLES

6.2 Oedema

6.2.1 CHAPTER AT A GLANCE

6.2.2 DEFINITION

6.2.3 DIAGNOSTIC ALGORITHM

6.2.4 DIFFERENTIALS LIST

6.2.5 KEY HISTORY FEATURES

6.2.6 KEY EXAMINATION FEATURES

6.2.7 KEY INVESTIGATIONS

6.2.8 KEY MANAGEMENT PRINCIPLES

6.3 Scrotal Swelling

6.3.1 CHAPTER AT A GLANCE

6.3.2 DEFINITION

6.3.3 DIAGNOSTIC ALGORITHM

6.3.4 DIFFERENTIALS LIST

6.3.5 KEY HISTORY FEATURES

6.3.6 KEY EXAMINATION FEATURES

6.3.7 KEY INVESTIGATIONS

6.3.8 KEY MANAGEMENT PRINCIPLES

7.1 Hypoglycaemia

7.1.1 CHAPTER AT A GLANCE

7.1.2 DEFINITION

7.1.3 DIAGNOSTIC ALGORITHM

7.1.4 DIFFERENTIALS LIST

7.1.5 KEY HISTORY FEATURES

7.1.6 KEY EXAMINATION FEATURES

7.1.7 KEY INVESTIGATIONS

7.1.8 KEY MANAGEMENT PRINCIPLES

7.2 Hyperglycaemia

7.2.1 CHAPTER AT A GLANCE

7.2.2 DEFINITION

7.2.3 DIAGNOSTIC ALGORITHM

7.2.4 DIFFERENTIALS LIST

7.2.5 KEY HISTORY FEATURES

7.2.6 KEY EXAMINATION FEATURES

7.2.7 KEY INVESTIGATIONS

7.2.8 KEY MANAGEMENT PRINCIPLES

8.1 Headache

8.1.1 CHAPTER AT A GLANCE

8.1.2 DEFINITION

8.1.3 DIAGNOSTIC ALGORITHM

8.1.4 DIFFERENTIALS LIST

8.1.5 KEY HISTORY FEATURES

8.1.6 KEY EXAMINATION FEATURES

8.1.7 KEY INVESTIGATIONS

8.1.8 KEY MANAGEMENT PRINCIPLES

8.2 Suspected Seizures

8.2.1 CHAPTER AT A GLANCE

8.2.2 DEFINITION

8.2.3 DIAGNOSTIC ALGORITHM

8.2.4 DIFFERENTIALS LIST

8.2.5 KEY HISTORY FEATURES

8.2.6 KEY EXAMINATION FEATURES

8.2.7 KEY INVESTIGATIONS

8.2.8 KEY MANAGEMENT PRINCIPLES

8.3 Acute Hemiparesis

8.3.1 CHAPTER AT A GLANCE

8.3.2 DEFINITION

8.3.3 DIAGNOSTIC ALGORITHM

8.3.4 DIFFERENTIALS LIST

8.3.5 KEY HISTORY FEATURES

8.3.6 KEY EXAMINATION FEATURES

8.3.7 KEY INVESTIGATIONS

8.3.8 KEY MANAGEMENT PRINCIPLES

8.4 Acute Lower‐Limb Weakness

8.4.1 CHAPTER AT A GLANCE

8.4.2 DEFINITION

8.4.3 DIAGNOSTIC ALGORITHM

8.4.4 DIFFERENTIALS LIST

8.4.5 KEY HISTORY FEATURES

8.4.6 KEY EXAMINATION FEATURES

8.4.7 KEY INVESTIGATIONS

8.4.8 KEY MANAGEMENT PRINCIPLES

8.5 Delirium and Agitation

8.5.1 CHAPTER AT A GLANCE

8.5.2 DEFINITION

8.5.3 DIAGNOSTIC ALGORITHM

8.5.4 DIFFERENTIALS LIST

8.5.5 KEY HISTORY FEATURES

8.5.6 KEY EXAMINATION FEATURES

8.5.7 KEY INVESTIGATIONS

8.5.8 KEY MANAGEMENT PRINCIPLES

8.6 Decreased Level of Consciousness

8.6.1 CHAPTER AT A GLANCE

8.6.2 DEFINITION

8.6.3 DIAGNOSTIC ALGORITHM

8.6.4 DIFFERENTIALS LIST

8.6.5 KEY HISTORY FEATURES

8.6.6 KEY EXAMINATION FEATURES

8.6.7 KEY INVESTIGATIONS

8.6.8 KEY MANAGEMENT PRINCIPLES

8.7 Dizziness

8.7.1 CHAPTER AT A GLANCE

8.7.2 DEFINITION

8.7.3 DIAGNOSTIC ALGORITHM

8.7.4 DIFFERENTIALS LIST

8.7.5 KEY HISTORY FEATURES

8.7.6 KEY EXAMINATION FEATURES

8.7.7 KEY INVESTIGATIONS

8.7.8 KEY MANAGEMENT PRINCIPLES

9.1 Urticaria

9.1.1 CHAPTER AT A GLANCE

9.1.2 DEFINITION

9.1.3 DIAGNOSTIC ALGORITHM

9.1.4 DIFFERENTIALS LIST

9.1.5 KEY HISTORY FEATURES

9.1.6 KEY EXAMINATION FEATURES

9.1.7 KEY INVESTIGATIONS

9.1.8 KEY MANAGEMENT PRINCIPLES

9.2 Non‐blanching Rash

9.2.1 CHAPTER AT A GLANCE

9.2.2 DEFINITION

9.2.3 DIAGNOSTIC ALGORITHM

9.2.4 DIFFERENTIALS LIST

9.2.5 KEY HISTORY FEATURES

9.2.6 KEY EXAMINATION FEATURES

9.2.7 KEY INVESTIGATIONS

9.2.8 KEY MANAGEMENT PRINCIPLES

9.3 Other Childhood Rashes

9.3.1 CHAPTER AT A GLANCE

9.3.2 DEFINITION

9.3.3 DIAGNOSTIC ALGORITHM

9.3.4 DIFFERENTIALS LIST

9.3.5 KEY HISTORY FEATURES

9.3.6 KEY EXAMINATION FEATURES

9.3.7 KEY INVESTIGATIONS

9.3.8 KEY MANAGEMENT PRINCIPLES

10.1 Limp

10.1.1 CHAPTER AT A GLANCE

10.1.2 DEFINITION

10.1.3 DIAGNOSTIC ALGORITHM

10.1.4 DIFFERENTIALS LIST

10.1.5 KEY HISTORY FEATURES

10.1.6 KEY EXAMINATION FEATURES

10.1.7 KEY INVESTIGATIONS

10.1.8 KEY MANAGEMENT PRINCIPLES

10.2 Swollen Joint

10.2.1 CHAPTER AT A GLANCE

10.2.2 DEFINITION

10.2.3 DIAGNOSTIC ALGORITHM

10.2.4 DIFFERENTIALS LIST

10.2.5 KEY HISTORY FEATURES

10.2.6 KEY EXAMINATION FEATURES

10.2.7 KEY INVESTIGATIONS

10.2.8 KEY MANAGEMENT PRINCIPLES

11.1 Neonatal Jaundice

11.1.1 CHAPTER AT A GLANCE

11.1.2 DEFINITION

11.1.3 DIAGNOSTIC ALGORITHM

11.1.4 DIFFERENTIALS LIST

11.1.5 KEY HISTORY FEATURES

11.1.6 KEY EXAMINATION FEATURES

11.1.7 KEY INVESTIGATIONS

11.1.8 KEY MANAGEMENT PRINCIPLES

11.2 The Unsettled Baby

11.2.1 CHAPTER AT A GLANCE

11.2.2 DEFINITION

11.2.3 DIAGNOSTIC ALGORITHM

11.2.4 DIFFERENTIALS LIST

11.2.5 KEY HISTORY FEATURES

11.2.6 KEY EXAMINATION FEATURES

11.2.7 KEY INVESTIGATIONS

11.2.8 KEY MANAGEMENT PRINCIPLES

11.3 Breastfeeding Advice

11.3.1 CHAPTER AT A GLANCE

11.3.2 BREASTFEEDING IN THE UK

11.3.3 BACKGROUND

11.3.4 HOW TO APPROACH DIFFICULTIES IN THE FIRST TWO WEEKS OF LIFE

11.3.5 HOW TO PROTECT BREASTFEEDING IN MEDICAL CONDITIONS

11.3.6 TOP TIPS

11.3.7 UNDERAPPRECIATED FACTS

12.1 The A to E Assessment

12.1.1 CHAPTER AT A GLANCE

12.1.2 TOP TIPS

12.1.3 KEY ASPECTS OF ASSESSMENT AND MANAGEMENT

12.2 Assessment of Consciousness

12.2.1 CHAPTER AT A GLANCE

12.2.2 AVPU

12.2.3 GCS

12.2.4 INTERPRETATION

12.3 Tips for Fluid Prescribing

12.3.1 CHAPTER AT A GLANCE

12.3.2 GENERAL PRINCIPLES

12.3.3 RESUSCITATION

12.3.4 REPLACEMENT

12.3.5 MAINTENANCE

12.3.6 MONITORING

12.3.7 SPECIAL SITUATIONS

12.4 Childhood Immunisations

12.4.1 CHAPTER AT A GLANCE

12.4.2 ROUTINE IMMUNISATIONS

12.4.3 SELECTIVE IMMUNISATIONS

12.4.4 CONSENTING FOR IMMUNISATIONS

12.4.5 COMMON QUESTIONS REGARDING IMMUNISATION

12.5 Safeguarding

12.5.1 CHAPTER AT A GLANCE

12.5.2 DEFINITION

12.5.3 TYPES OF CHILD ABUSE

12.5.4 KEY HISTORY FEATURES

12.5.5 KEY EXAMINATION FEATURES

12.5.6 KEY INVESTIGATIONS

12.5.7 THE CHALLENGES OF CHILD PROTECTION WORK

12.5.8 TWO CASES

12.5.9 SUMMARY POINTS

12.5.10 ADDITIONAL REFERENCES

13.1 Sepsis Management

13.1.1 KEY POINTS

13.1.2 ADDITIONAL REFERENCE

13.2 Anaphylaxis Management

13.2.1 KEY POINTS

13.2.2 IMPORTANT NOTES ABOUT ADRENALINE

13.2.3 ADDITIONAL REFERENCES

13.3 Acute Asthma Management

13.3.1 KEY POINTS

13.3.2 ADDITIONAL REFERENCES

13.4 Prolonged Seizure Management

13.4.1 KEY POINTS

13.4.2 ADDITIONAL REFERENCES

13.5 Raised Intracranial Pressure Management

13.5.1 KEY POINTS

13.5.2 SIGNS OF RAISED INTRACRANIAL PRESSURE

Guidelines

Index

End User License Agreement

List of Tables

Chapter 1.1

Table 1.1.1

Bedside tests of use in patients presenting with wheeze

Table 1.1.2

Blood tests of use in patients presenting with wheeze

Table 1.1.3

Imaging modalities of use in patients presenting with wheeze

Table 1.1.4

Special tests of use in patients presenting with wheeze

Chapter 1.2

Table 1.2.1

Bedside tests of use in patients presenting with stridor

Table 1.2.2

Blood tests of use in patients presenting with stridor

Table 1.2.3

Imaging modalities of use in patients presenting with stridor

Table 1.2.4

Special tests of use in patients presenting with stridor

Chapter 1.3

Table 1.3.1

Bedside tests of use in patients presenting with difficulty in b...

Table 1.3.2

Blood tests of use in patients presenting with difficulty in bre...

Table 1.3.3

Imaging modalities of use in patients presenting with difficulty...

Table 1.3.4

Special tests of use in patients presenting with difficulty in b...

Chapter 2.1

Table 2.1.1

Bedside tests of use in patients presenting with cyanosis

Table 2.1.2

Blood tests of use in patients presenting with cyanosis

Table 2.1.3

Imaging Modalities of use in patients presenting with cyanosis

Table 2.1.4

Special tests of use in patients presenting with cyanosis

Chapter 2.2

Table 2.2.1 End‐of‐bed assessment

Table 2.2.2

Airway assessment

Table 2.2.3

Breathing assessment

Table 2.2.4

Circulation assessment

Table 2.2.5

Disability assessment

Table 2.2.6 Exposure assessment

Table 2.2.7

Bedside tests of use in patients presenting with circulatory col...

Table 2.2.8

Blood tests of use in patients presenting with circulatory colla...

Table 2.2.9

Imaging modalities of use in patients presenting with circulator...

Table 2.2.10

Special tests of use in patients presenting with circulatory co...

Chapter 2.3

Table 2.3.1

Bedside tests of use in patients presenting with syncope

Table 2.3.2

Blood tests of use in patients presenting with syncope

Table 2.3.3

Special tests of use in patients presenting with syncope

Chapter 2.4

Table 2.4.1

Bedside tests of use in patients presenting with chest pain

Table 2.4.2

Blood tests of use in patients presenting with chest pain

Table 2.4.3

Imaging modalities of use in patients presenting with chest pain...

Table 2.4.4

Special tests of use in patients presenting with chest pain

Chapter 2.5

Table 2.5.1

Bedside tests of use in patients presenting with palpitations

Table 2.5.2

Blood tests of use in patients presenting with palpitations

Table 2.5.3

Imaging modalities of use in patients presenting with palpitatio...

Table 2.5.4

Special tests of use in patients presenting with palpitations

Chapter 3.1

Table 3.1.1

Viral causes of fever in children

Table 3.1.2

Bedside tests of use in patients presenting with fever

Table 3.1.3

Blood tests of use in patients presenting with fever

Table 3.1.4

Imaging modalities of use in patients presenting with fever

Table 3.1.5

Special tests of use in patients presenting with fever

Chapter 3.2

Table 3.2.1

Bedside tests of use in returning travellers presenting with fev...

Table 3.2.2

Blood tests of use in returning travellers presenting with fever...

Table 3.2.3

Imaging modalities of use in returning travellers presenting wit...

Table 3.2.4

Special tests of use in returning travellers presenting with fev...

Chapter 3.3

Table 3.3.1

Bedside tests of use in patients presenting with lymphadenopathy...

Table 3.3.2

Blood tests of use in patients presenting with lymphadenopathy

Table 3.3.3

Imaging tests of use in patients presenting with lymphadenopathy...

Table 3.3.4

Special tests of use in patients presenting with lymphadenopathy...

Chapter 4.1

Table 4.1.1

Bedside tests of use in patients presenting with bruising

Table 4.1.2

Blood tests of use in patients presenting with bruising

Table 4.1.3

Imaging modalities of use in patients presenting with bruising

Table 4.1.4

Special tests of use in patients presenting with bruising

Chapter 4.2

Table 4.2.1

Bedside tests of use in patients presenting with pallor

Table 4.2.2

Blood tests of use in patients presenting with pallor

Table 4.2.3

Imaging modalities of use in patients presenting with pallor A v...

Table 4.2.4

Special tests of use in patients presenting with pallor

Chapter 5.1

Table 5.1.1

Bedside tests of use in patients presenting with abdominal pain...

Table 5.1.2

Blood tests of use in patients presenting with abdominal pain

Table 5.1.3

Imaging modalities of use in patients presenting with abdominal ...

Table 5.1.4

Special tests of use in patients presenting with abdominal pain...

Chapter 5.2

Table 5.2.1

Bedside tests of use in patients presenting with an abdominal ma...

Table 5.2.2

Blood tests of use in patients presenting with an abdominal mass...

Table 5.2.3

Imaging modalities of use in patients presenting with an abdomin...

Table 5.2.4

Special tests of use in patients presenting with an abdominal ma...

Chapter 5.3

Table 5.3.1

Bedside tests of use in patients presenting with vomiting

Table 5.3.2

Blood tests of use in patients presenting with vomiting

Table 5.3.3

Imaging modalities of use in patients presenting with vomiting

Table 5.3.4

Special tests of use in patients presenting with vomiting

Chapter 5.4

Table 5.4.1

Bedside tests of use in patients presenting with diarrhoea

Table 5.4.2

Blood tests of use in patients presenting with diarrhoea

Table 5.4.3

Imaging modalities of use in patients presenting with diarrhoea...

Table 5.4.4

Special tests of use in patients presenting with diarrhoea

Chapter 5.5

Table 5.5.1

Bedside tests of use in patients presenting with jaundice

Table 5.5.2

Blood tests of use in patients presenting with jaundice

Table 5.5.3

Imaging modalities of use in patients presenting with jaundice

Table 5.5.4

Special tests of use in patients presenting with jaundice

Chapter 5.6

Table 5.6.1

Bedside tests of use in patients presenting with faltering growt...

Table 5.6.2

Blood tests of use in patients presenting with faltering growth...

Table 5.6.3

Imaging modalities of use in patients presenting with faltering ...

Table 5.6.4

Special tests of use in patients presenting with faltering growt...

Chapter 6.1

Table 6.1.1

Bedside tests of use in patients presenting with haematuria

Table 6.1.2

Blood tests of use in patients presenting with haematuria

Table 6.1.3

Imaging modalities of use in patients presenting with haematuria...

Table 6.1.4

Special tests of use in patients presenting with haematuria

Chapter 6.2

Table 6.2.1

Bedside tests of use in patients presenting with oedema

Table 6.2.2

Blood tests of use in patients presenting with oedema

Table 6.2.3

Imaging modalities of use in patients presenting with oedema

Table 6.2.4

Special tests of use in patients presenting with oedema

Chapter 6.3

Table 6.3.1

Bedside tests of use in patients presenting with scrotal swellin...

Table 6.3.2

Blood tests of use in patients presenting with scrotal swelling...

Table 6.3.3

Imaging modalities of use in patients presenting with scrotal sw...

Chapter 7.1

Table 7.1.1

Bedside tests of use in patients presenting with hypoglycaemia

Table 7.1.2

Blood tests of use in patients presenting with hypoglycaemia

Table 7.1.3

Imaging modalities of use in patients presenting with hypoglycae...

Table 7.1.4

Special tests of use in patients presenting with hypoglycaemia

Chapter 7.2

Table 7.2.1

Bedside tests of use in patients presenting with hyperglycaemia...

Table 7.2.2

Blood tests of use in patients presenting with hyperglycaemia

Table 7.2.3

Special tests of use in patients presenting with hyperglycaemia...

Chapter 8.1

Table 8.1.1

Bedside tests of use in children presenting with headache

Table 8.1.2

Blood tests of use in children presenting with headache

Table 8.1.3

Imaging modalities of use in children presenting with headache

Table 8.1.4

Cerebrospinal fluid (lumbar puncture) tests of use in children p...

Chapter 8.2

Table 8.2.1

Bedside tests of use in patients presenting with suspected seizu...

Table 8.2.2

Blood tests of use in patients presenting with suspected seizure...

Table 8.2.3

Imaging modalities of use in patients presenting with suspected ...

Table 8.2.4

Special tests of use in patients presenting with suspected seizu...

Chapter 8.3

Table 8.3.1

Bedside tests of use in patients presenting with acute hemipares...

Table 8.3.2

Blood tests of use in patients presenting with acute hemiparesis...

Table 8.3.3

Imaging modalities of use in patients presenting with acute hemi...

Table 8.3.4

Special tests of use in patients presenting with acute hemipares...

Chapter 8.4

Table 8.4.1

Bedside tests of use in patients presenting with acute lower‐lim...

Table 8.4.2

Blood tests of use in patients presenting with acute lower‐limb ...

Table 8.4.3

Imaging modalities of use in patients presenting with acute lowe...

Table 8.4.4

Additional tests in patients presenting with acute lower‐limb we...

Chapter 8.5

Table 8.5.1

Bedside tests of use in patients presenting with delirium and ag...

Table 8.5.2

Blood tests of use in patients presenting with delirium and agit...

Table 8.5.3

Imaging modalities of use in patients presenting with delirium a...

Table 8.5.4

Special tests of use in patients presenting with delirium and ag...

Chapter 8.6

Table 8.6.1

Bedside tests of use in patients presenting with decreased level...

Table 8.6.2

Blood tests of use in patients presenting with decreased level o...

Table 8.6.3

Imaging modalities of use in patients presenting with decreased ...

Table 8.6.4

Special tests of use in patients presenting with decreased level...

Chapter 8.7

Table 8.7.1

Bedside tests of use in patients presenting with dizziness

Table 8.7.2

Blood tests of use in patients presenting with dizziness

Table 8.7.3

Imaging modalities of use in patients presenting with dizziness...

Table 8.7.4

Special tests of use in patients presenting with dizziness

Chapter 9.1

Table 9.1.1

Blood tests of use in patients presenting with urticaria

Table 9.1.2

Imaging modalities of use in patients presenting with urticaria...

Table 9.1.3

Special tests of use in patients presenting with urticaria

Chapter 9.2

Table 9.2.1

Bedside tests of use in patients presenting with non‐blanching r...

Table 9.2.2

Blood tests of use in patients presenting with non‐blanching ras...

Chapter 9.3

Table 9.3.1

Blood tests of use in patients presenting with childhood rashes...

Table 9.3.2

Imaging modalities of use in patients presenting with childhood ...

Table 9.3.3

Special tests of use in patients presenting with childhood rashe...

Chapter 10.1

Table 10.1.1

Bedside tests of use in patients presenting with a limp

Table 10.1.2

Blood tests of use in patients presenting with a limp

Table 10.1.3

Imaging modalities of use in patients presenting with a limp

Table 10.1.4

Special tests of use in patients presenting with a limp

Chapter 10.2

Table 10.2.1

Bedside tests of use in patients presenting with swollen joints...

Table 10.2.2

Blood tests of use in patients presenting with swollen joints

Table 10.2.3

Imaging modalities of use in patients presenting with swollen j...

Table 10.2.4

Special tests of use in patients presenting with swollen joints...

Chapter 11.1

Table 11.1.1

Bedside tests of use in patients presenting with neonatal jaund...

Table 11.1.2

Blood tests of use in patients presenting with neonatal jaundic...

Table 11.1.3

Imaging modalities of use in patients presenting with neonatal ...

Table 11.1.4

Special tests of use in patients presenting with neonatal jaund...

Chapter 11.2

Table 11.2.1

Bedside tests of use in infants presenting with unsettled behav...

Table 11.2.2

Blood tests of use in infants presenting with unsettled behavio...

Table 11.2.3

Imaging modalities of use in infants presenting with unsettled ...

Table 11.2.4

Special Tests Of Use In Infants Presenting With Unsettled Behav...

Chapter 12.1

Table 12.1.1

Airway assessment

Table 12.1.2

Airway management options

Table 12.1.3

Breathing assessment

Table 12.1.4

Breathing management options

Table 12.1.5

Circulation assessment

Table 12.1.6

Circulation management options

Table 12.1.7

Disability assessment

Table 12.1.8

Disability management options

Table 12.1.9

Exposure assessment

Table 12.1.10

Exposure management options

Chapter 12.2

Table 12.2.1

Glasgow Coma Scale

Chapter 12.4

Table 12.4.1

Routine immunisations in the UK

Table 12.4.2

Selective immunisations in the UK

Chapter 12.5

Table 12.5.1

Areas for investigation

Chapter 13.2

Table 13.2.1

Medications used in the management of anaphylaxis

List of Illustrations

Chapter 1.1

Figure 1.1.1 Diagnostic algorithm for the presentation of wheeze.

Figure 1.1.2 Changes in chronic obstructive respiratory disease. (A) Harriso...

Figure 1.1.3 Harrison’s sulcus – note the chronic indentation of the lower r...

Figure 1.1.4 A child using a peak flow meter.

Figure 1.1.5 A chest x‐ray is not required for a diagnosis of bronchiolitis,...

Figure 1.1.6 A chest x‐ray showing hyperinflation in acute asthma.

Figure 1.1.7 A spacer is an essential device when administering inhaled bron...

Chapter 1.2

Figure 1.2.1 Diagnostic algorithm for the presentation of stridor.

Figure 1.2.2 Anatomical diagram indicating the key structures in the upper a...

Figure 1.2.3 Signs of increased work of breathing. Recognition of respirator...

Figure 1.2.4 Laryngoscopy view of (A) normal larynx, (B) epiglottitis and (C...

Figure 1.2.5 Chest x‐ray of an anterior mediastinal mass.

Figure 1.2.6 The ‘steeple sign’. The shape of a church steeple is produced b...

Chapter 1.3

Figure 1.3.1 Diagnostic algorithm for the presentation of difficulty in brea...

Figure 1.3.2 Right upper lobe collapse and consolidation in focal pneumonia....

Figure 1.3.3 Left upper lobe collapse due to pneumonia – veil‐like opacity o...

Figure 1.3.4 Two chest x‐rays showing pleural effusions, commonly seen as a ...

Figure 1.3.5 A round pneumonia is usually a paediatric phenomenon, due to im...

Figure 1.3.6 Left‐sided tension pneumothorax with mediastinal shift away

Chapter 2.1

Figure 2.1.1 Central cyanosis in a baby.

Figure 2.1.2 Diagnostic algorithm for the presentation of cyanosis.

Figure 2.1.3 Blood flow through the heart in Tetralogy of Fallot. There is a...

Figure 2.1.4 Blood flow through the heart in tricuspid atresia. Inability of...

Figure 2.1.5 Blood flow through the heart in truncus arteriosus. The single ...

Figure 2.1.6 Blood flow through the heart in transposition of the great arte...

Figure 2.1.7 In the absence of a detailed history, careful examination of th...

Figure 2.1.8 Cardiomegaly on chest x‐ray due to Ebstein’s anomaly

Figure 2.1.9 Safe triangle for chest drain insertion – bordered anteriorly b...

Figure 2.1.10 Left‐sided tension pneumothorax with mediastinal shift away.

Chapter 2.2

Figure 2.2.1 Diagnostic algorithm for the presentation of circulatory shock....

Figure 2.2.2 Relationships between essential cardiovascular states, explaini...

Figure 2.2.3 Blood flow in a duct‐dependent circulation in a baby with inter...

Figure 2.2.4 Blood flow through the heart in hypoplastic left heart syndrome...

Chapter 2.3

Figure 2.3.1 Diagnostic algorithm for the presentation of syncope.

Figure 2.3.2 Torsade de pointes is a polymorphic form of ventricular tachyca...

Figure 2.3.3 There are several stereotypical prodromal features of vasovagal...

Figure 2.3.4 The tilt‐table test. Procedure: the child lies on a bed and is ...

Chapter 2.4

Figure 2.4.1 Diagnostic algorithm for the presentation of chest pain.

Figure 2.4.2 Hypertrophic cardiomyopathy causes a thickened left ventricular...

Figure 2.4.3 Horizontal arm traction involves steadily pulling a flexed arm ...

Figure 2.4.4 Passive chest wall stretch, otherwise known as the ‘crowing roo...

Figure 2.4.5 ‘Chest wall hooking’ involves hooking fingers beneath the costa...

Figure 2.4.6 (A) Anterior and (B) lateral view of an anterior mediastinal ma...

Figure 2.4.7 Axial computed tomography of aortic dissection with involvement...

Figure 2.4.8 Computed tomographic pulmonary angiogram showing filling defect...

Chapter 2.5

Figure 2.5.1 Diagnostic algorithm for the presentation of palpitations.

Figure 2.5.2 In premature atrial contractions (PACs), usually the QRS comple...

Figure 2.5.3 Electrocardiogram in a 7‐year‐old boy showing physiological sin...

Figure 2.5.4 Supraventricular tachycardia (SVT) is a narrow complex tachycar...

Figure 2.5.5 The electrocardiogram is the definitive tool when assessing and...

Chapter 3.1

Figure 3.1.1 Diagnostic algorithm for the presentation of fever.In 2019, a...

Figure 3.1.2 Vesicles on the palm in hand, food and mouth disease, usually c...

Figure 3.1.3 Findings in Kawasaki disease. (A) Strawberry tongue; (B) non‐pu...

Figure 3.1.4 Dull and retracted tympanic membrane as seen in otitis media on...

Figure 3.1.5 Strawberry tongue in scarlet fever.

Figure 3.1.6 The classic rash of chickenpox involves pruritic, fluid‐filled ...

Figure 3.1.7 Left‐sided consolidation with empyema.

Figure 3.1.8 Left‐sided empyema with a clear convexity due to the pleural co...

Chapter 3.2

Figure 3.2.1 The Tropics and the Subtropics.

Figure 3.2.2 Diagnostic algorithm for the presentation of fever in the retur...

Figure 3.2.3 Areas with endemic malaria, requiring travel precautions.

Figure 3.2.4 Tuberculosis has many extra‐pulmonary manifestations, which sho...

Figure 3.2.5 Signs and symptoms associated with human immunodeficiency virus...

Figure 3.2.6 Petechiae in the antecubital fossa following the tourniquet tes...

Figure 3.2.7 The differential diagnosis for tropical infections is wide. Thi...

Chapter 3.3

Figure 3.3.1 Diagnostic algorithm for the presentation of lymphadenopathy.

Figure 3.3.2 Children with Kawasaki disease are often very miserable, out of...

Figure 3.3.3 Child with cervical lymphadenopathy.

Figure 3.3.4 Location of palpable peripheral lymph nodes.

Figure 3.3.5 Blood film showing three large blasts in a patient with precurs...

Chapter 4.1

Figure 4.1.1 Diagnostic algorithm for the presentation of bruising.

Figure 4.1.2 Erythema nodosum.

Figure 4.1.3 Newborn babies require vitamin K at birth. This is commonly giv...

Figure 4.1.4 Always consider non‐accidental injury in any bruising in a chil...

Figure 4.1.5 Vitamin C deficiency was classically associated with sailors du...

Figure 4.1.6 Damage to a blood vessel triggers a cascade of reactions. Endot...

Figure 4.1.7 Thrombocytopenia and one reactive lymphocyte in a child with im...

Chapter 4.2

Figure 4.2.1 Diagnostic algorithm for the presentation of pallor.

Figure 4.2.2 Haematopoietic stem cells are pluripotent and reside in the bon...

Figure 4.2.3 The haemoglobin molecule is made up of two alpha globin chains ...

Figure 4.2.4 Under normal circumstances, oxygen is collected from the lungs ...

Figure 4.2.5 In sickle cell disease, haemoglobin only exists as isolated uni...

Figure 4.2.6 There are several types of globin chains involved in haemoglobi...

Figure 4.2.7 Sickle cell disease is autosomal recessive. Offspring born to p...

Figure 4.2.8 Microcytic hypochromic red cells (arrowhead) and target cells (...

Figure 4.2.9 Spherocytes (some of which are indicated by arrows) in a patien...

Figure 4.2.10 Red cell fragments (some of which are indicated by arrows) in ...

Figure 4.2.11 Three sickle‐shaped red cells (arrows) in a patient with sickl...

Figure 4.2.12 Blood film showing multiple target cells and microcytic red ce...

Chapter 5.1

Figure 5.1.1 Diagnostic algorithm for the presentation of abdominal pain.

Figure 5.1.2 Intussusception: an intussusception can involve the telescoping...

Figure 5.1.3 Volvulus: twisting of the gut, usually on a base of narrow mese...

Figure 5.1.4 Abdominal regions can either be divided into nine areas (red) o...

Figure 5.1.5 Abdominal scars.

1. Kocher’s incision:

hepatic surgery, b...

Figure 5.1.6 Low intestinal obstruction in a neonate with meconium ileus (bu...

Figure 5.1.7 Abdominal x‐ray in a 2‐year‐old with intussusception, shown by ...

Figure 5.1.8 Contrast study demonstrating a normal duodenojejunal (DJ) flexu...

Chapter 5.2

Figure 5.2.1 Diagnostic algorithm for the presentation of abdominal mass.

Figure 5.2.2 The anatomical areas of the abdomen or the simplified four quad...

Figure 5.2.3 A Bristol Stool Chart is an extremely useful tool in determinin...

Figure 5.2.4 Wilms’ tumour. Computed tomography (CT) abdomen showing a right...

Figure 5.2.5 Different causes of hydronephrosis.

Figure 5.2.6 Faecal loading

.

Abdominal radiograph showing faecal loading in ...

Figure 5.2.7 A depiction of a normal rectum showing normal stool collection ...

Figure 5.2.8 Micturating cystourethrogram (MCUG) done to evaluate the cause ...

Figure 5.2.9 A dimercaptosuccinic acid (DMSA) scan was done to evaluate the ...

Chapter 5.3

Figure 5.3.1 Diagnostic algorithm for the presentation of vomiting.

Figure 5.3.2 Pyloric stenosis is a condition affecting babies at around 6 we...

Figure 5.3.3 Abdominal x‐ray demonstrating the double bubble sign of duodena...

Figure 5.3.4 Ultrasound demonstrating pyloric stenosis. (A) Transverse secti...

Chapter 5.4

Figure 5.4.1 Diagnostic algorithm for the presentation of diarrhoea.

Figure 5.4.2 Typical pattern of

Escherichia coli

0157 infection in children....

Figure 5.4.3 Ultrasound abdomen demonstrating intussusception. Note the clas...

Chapter 5.5

Figure 5.5.1 Diagnostic algorithm for the presentation of jaundice.

Figure 5.5.2 The metabolism of bilirubin. Red blood cells are degraded withi...

Figure 5.5.3 Scleral icterus in a baby with jaundice.

Figure 5.5.4 Signs of finger clubbing may be seen in chronic liver disease, ...

Chapter 5.6

Figure 5.6.1 Diagnostic algorithm for the presentation of faltering growth....

Figure 5.6.2 National Institute for Health and Care Excellence suggests thre...

Chapter 6.1

Figure 6.1.1 Diagnostic algorithm for the presentation of haematuria.

Figure 6.1.2 How to perform and interpret a urine dipstick. 1. Ensure urine ...

Figure 6.1.3 A ureterorenoscopy is performed under general anaesthetic and i...

Figure 6.1.4 Renal calculi as seen on an abdominal x‐ray.

Chapter 6.2

Figure 6.2.1 Diagnostic Algorithm for the Presentation of Oedema.

Figure 6.2.2 Oedema can be visually assessed by the appearance of swollen de...

Figure 6.2.3 Starling’s hypothesis helps explain fluid shifts between the in...

Chapter 6.3

Figure 6.3.1 Diagnostic algorithm for the presentation of scrotal swelling....

Figure 6.3.2 (A) An indirect hernia is caused by abdominal contents that pas...

Figure 6.3.3 The difference between a non‐communicating and a communicating ...

Figure 6.3.4 A varicocele involves abnormal distension of the pampiniform ve...

Figure 6.3.5 Diagram of inflammation of the epididymis and testicle in epidi...

Figure 6.3.6 A testicular ultrasound demonstrating a testicular torsion. Nor...

Chapter 7.1

Figure 7.1.1 Diagnostic algorithm for the presentation of hypoglycaemia.

Figure 7.1.2 Normal glucose homeostasis.

Figure 7.1.3 Causes of hypoglycaemia according to age. Age is an important i...

Figure 7.1.4 There are a variety of point‐of‐care blood sugar monitors that ...

Figure 7.1.5 Regardless of the cause, significant or symptomatic hypoglycaem...

Figure 7.1.6 There are variety of powdered carbohydrate drink mixes for use ...

Chapter 7.2

Figure 7.2.1 Diagnostic algorithm for the presentation of hyperglycaemia.

Figure 7.2.2 The pancreas has both exocrine and endocrine functions. Exocrin...

Chapter 8.1

Figure 8.1.1 Diagnostic algorithm for the presentation of headache.

Figure 8.1.2 Pre‐ and post‐contrast computed tomography of a glioma in a 12‐...

Figure 8.1.3 Layout of the dural venous sinuses of the brain (simplified): a...

Figure 8.1.4 Detecting meningism on clinical examination: Kernig’s sign (ina...

Figure 8.1.5 Papilloedema (right) compared with a normal optic disc (left)....

Figure 8.1.6 Position of the sinuses with approximate age at pneumatisation....

Figure 8.1.7 Cerebrospinal fluid (CSF) manometry for use in idiopathic intra...

Chapter 8.2

Figure 8.2.1 Diagnostic algorithm for the presentation of suspected seizures...

Figure 8.2.2 Magnetic resonance image showing type 1 Chiari malformation, wi...

Figure 8.2.3 Magnetic resonance image of Chiari malformation with syringomye...

Figure 8.2.4 Electroencephalogram from a 3‐year‐old girl who presented with ...

Figure 8.2.5 Electroencephalogram of a 7‐year‐old boy with childhood absence...

Figure 8.2.6 Electroencephalogram from a 11‐year‐old boy in absence status e...

Chapter 8.3

Figure 8.3.1 Diagnostic algorithm for the presentation of acute hemiparesis....

Figure 8.3.2 Computed tomography brain showing an acute left‐sided subdural ...

Figure 8.3.3 Computed tomography brain showing a large acute right frontal i...

Figure 8.3.4 (A) T2‐weighted axial magnetic resonance imaging (MRI). (B) Dif...

Figure 8.3.5 T2‐weighted magnetic resonance imaging. There is a large right‐...

Figure 8.3.6 Computed tomography brain showing a mass in the 4th ventricle (...

Chapter 8.4

Figure 8.4.1 Diagnostic algorithm for the presentation of acute lower‐limb w...

Figure 8.4.2 Spinal space‐occupying lesions can be divided into intramedulla...

Figure 8.4.3 Magnetic resonance imaging of the spine showing an ill‐defined ...

Figure 8.4.4 The motor neuron functions when an action potential reaches a n...

Figure 8.4.5 Magnetic resonance imaging of the brain showing multiple, large...

Figure 8.4.6 Magnetic resonance imaging of the spine showing cauda equina co...

Chapter 8.5

Figure 8.5.1 Diagnostic algorithm for the presentation of delirium and agita...

Figure 8.5.2 Signs of basal skull fracture: mastoid ecchymosis, known as ‘ba...

Chapter 8.6

Figure 8.6.1 Diagnostic algorithm for the presentation of a decreased level ...

Figure 8.6.2 The Monroe–Kellie hypothesis explains that brain tissue, blood ...

Figure 8.6.3 Drugs and alcohol may be ingested in combination or in isolatio...

Figure 8.6.4 Ammonia is primarily derived from ingested nitrogenous compound...

Figure 8.6.5 If there is a failure of this pathway, extrahepatic organs, suc...

Chapter 8.7

Figure 8.7.1 Diagnostic algorithm for the presentation of dizziness.

Figure 8.7.2 Anatomical diagram of the ear, showing some of the structures t...

Chapter 9.1

Figure 9.1.1 Diagnostic algorithm for the presentation of urticaria.

Figure 9.1.2 Urticaria is characterised by a raised, itchy erythematous rash...

Figure 9.1.3 Erythema multiforme: an urticaria mimic.

Figure 9.1.4 Dermatographism is a benign skin disorder in which urticaria ap...

Chapter 9.2

Figure 9.2.1 Diagnostic algorithm for the presentation of non‐blanching rash...

Figure 9.2.2 Immune thrombocytopenic purpura.

Figure 9.2.3 Typical appearance of a petechial rash with lesions <2 mm.

Figure 9.2.4 Typical appearance of a purpuric rash with lesions >2 mm.

Figure 9.2.5 Distribution of petechial rash caused by increased pressure in ...

Figure 9.2.6 Body areas typically affected by the rash of Henoch–Schönlein p...

Figure 9.2.7 Petechial rash on the face and trunk in a child with meningococ...

Chapter 9.3

Figure 9.3.1 Diagnostic algorithm for the presentation of childhood rash.

Figure 9.3.2 Eczema herpeticum on the face.

Figure 9.3.3 The classic rash of chickenpox involves pruritic, fluid‐filled ...

Figure 9.3.4 Reactivation of herpes zoster infection leads to shingles, whic...

Figure 9.3.5 Impetigo on the scalp, characterised by the golden crusted lesi...

Figure 9.3.6 Vesicles on the palm in hand, food and mouth disease, usually c...

Chapter 10.1

Figure 10.1.1 Diagnostic algorithm for the presentation of a limp.

Figure 10.1.2 Compartment syndrome occurs when swelling of injured muscles c...

Figure 10.1.3 Although named ‘slipped upper femoral epiphysis’, this is actu...

Figure 10.1.4 Anteroposterior view of a left slipped upper femoral epiphysis...

Chapter 10.2

Figure 10.2.1 Diagnostic algorithm for the presentation of a swollen joint....

Figure 10.2.2 X‐ray of osteosarcoma in the femur (accounts for 40% of osteos...

Figure 10.2.3 X‐ray of osteosarcoma in the humerus (accounts for 15% of oste...

Figure 10.2.4 Magnetic resonance imaging of pelvic Ewing’s sarcoma.

Chapter 11.1

Figure 11.1.1 Diagnostic algorithm for the presentation of neonatal jaundice...

Figure 11.1.2 Baby with jaundiced skin.

Figure 11.1.3 Rhesus Disease. Formation of rhesus antibodies occurs during d...

Figure 11.1.4 Physiological jaundice: the process of metabolism of bilirubin...

Figure 11.1.5 ABO Incompatibility. Maternal antibodies (immunoglobulin G) to...

Figure 11.1.6 Treatment threshold chart for ≥38 weeks’ gestation.

Figure 11.1.7 Baby being treated for jaundice under phototherapy lights.

Chapter 11.2

Figure 11.2.1 Diagnostic algorithm for the presentation of an unsettled baby...

Figure 11.2.2 Hair tourniquet. Courtesy of James Heilman, MD, CC BY‐SA 3.0....

Figure 11.2.3 Centile chart of crying time in the first 12 weeks of life, as...

Figure 11.2.4 Diagnosis and management flowchart for cow’s milk protein alle...

Chapter 11.3

Figure 11.3.1 Diagnostic and management flowchart for breastfeeding difficul...

Chapter 12.1

Figure 12.1.1 The airway assessment of children has fundamental differences ...

Chapter 12.3

Figure 12.3.1 Enteral replacement and the ‘fluid challenge’. In a non‐shocke...

Figure 12.3.2 Instructions for making a simple oral rehydration solution (OR...

Chapter 12.5

Figure 12.5.1 Factors to consider when assessing the probability of safeguar...

Figure 12.5.2 A body map with markings for suspicious areas for bruising fro...

Figure 12.5.3 Suspicious areas for bruising from the back.

Chapter 13.1

Figure 13.1.1 Algorithm for the approach to the management of sepsis.

Chapter 13.2

Figure 13.2.1 Algorithm for the approach to the management of anaphylaxis.

Chapter 13.3

Figure 13.3.1 Algorithm for the management of acute severe and life‐threaten...

Chapter 13.4

Figure 13.4.1 Algorithm for the approach to the management of prolonged seiz...

Chapter 13.5

Figure 13.5.1 Algorithm for the emergency management of raised intracranial ...

Guide

Cover Page

Series Page

Title Page

Copyright

List of Contributors

List of Contributors

About the Companion Website

How to Use This Book

Table of Contents

Begin Reading

Guidelines

Index

WILEY END USER LICENSE AGREEMENT

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The Clinical Guides series

Series Editor: Christian Fielder Camm

The Clinical Guides are a brand new resource for junior doctors and medical students. They provide practical and concise information on symptoms, common conditions, and day‐to‐day problems faced in the clinical environment. They are easy to navigate and allow swift access to information as it is needed, with step‐by‐step guidance on investigations, decision‐making and interventions, and how to survive and thrive on clinical rotations and attachments.

Clinical Guide to Paediatrics

Edited by

Rachel Varughese

Specialist Registrar in Paediatrics

Oxford University Hospitals NHS Foundation Trust, UK

and

Anna Mathew

Consultant Paediatrician

University Hospitals Sussex NHS Foundation Trust, Worthing, UK

Chair of MRCPCH Clinical Examinations, RCPCH

Series Editor:

Christian Fielder Camm

Cardiology Specialist Registrar

Royal Berkshire Hospital, Reading, UK

This edition first published 2022© 2022 John Wiley & Sons Ltd

All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, except as permitted by law. Advice on how to obtain permission to reuse material from this title is available at http://www.wiley.com/go/permissions.

The right of Rachel Varughese and Anna Mathew to be identified as the authors of the editorial material in this work has been asserted in accordance with law.

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Library of Congress Cataloging‐in‐Publication Data

Names: Varughese, Rachel, editor. | Mathew, Anna, editor.Title: Clinical guide to paediatrics / edited by Rachel Varughese and Anna Mathew.Other titles: Clinical guides series.Description: First edition. | Hoboken, NJ : Wiley‐Blackwell, 2021. | Series: Clinical guides series | Includes bibliographical references and  index.Identifiers: LCCN 2021027295 (print) | LCCN 2021027296 (ebook) | ISBN  9781119539117 (paperback) | ISBN 9781119539124 (adobe pdf) | ISBN  9781119539094 (epub)Subjects: MESH: PediatricsClassification: LCC RJ61 (print) | LCC RJ61 (ebook) | NLM WS 100 | DDC  618.92–dc23LC record available at https://lccn.loc.gov/2021027295LC ebook record available at https://lccn.loc.gov/2021027296

Cover image: WileyCover design: © Gettyimages\PIXOLOGICSTUDIO/SCIENCE PHOTO LIBRARY

List of Contributors

Abdulhakim AbdurrazaqDepartment of Paediatrics, Walsall Manor Hospital, Walsall Healthcare NHS Trust, Walsall, UK

Geetha AnandDepartment of Paediatrics, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK

Rachel AthertonDepartment of Paediatrics, Oxford University Hospitals NHS Foundation Trust, Oxford, UK

Rebecca BrownDepartment of Paediatrics, London School of Paediatrics, London, UK

Dannika BuckleyDepartment of Paediatrics, University Hospitals Sussex NHS Foundation Trust, Worthing, West Sussex, UK

Catarina Pinto CarrDepartment of Paediatrics, East Surrey Hospital, Surrey and Sussex Healthcare NHS Trust, UK

Benjamin CarterDepartment of Paediatrics, University Hospitals Sussex NHS Foundation Trust, Chichester, UK

Samyami S. ChowdhuryDepartment of Paediatric Neurology, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK

Duana CookDepartment of Paediatrics, University Hospitals Sussex NHS Foundation Trust, Worthing, UK

Eleanor DuckworthUniversity College Hospital, University College London Hospitals NHS Foundation Trust, London, UK

Gary FoleyDepartment of Paediatrics, Centre for Genomics and Child Health, London, UK

Emma HughesDepartment of Paediatrics, Great Western Hospitals NHS Foundation Trust, Swindon, UK

Sally‐Anne HultonDepartment of Paediatric Nephrology, Birmingham Women’s and Children’s NHS Foundation Trust, Birmingham, UK

Robin JosephOxford University Hospitals NHS Foundation Trust, Oxford, UK

Umaiyal KugathasanUniversity Hospitals Sussex NHS Trust, Brighton, UK

Ilana LeveneNational Perinatal Epidemiology Unit, University of Oxford, Oxford, UK

Anna MathewDepartment of Paediatrics, University Hospitals Sussex NHS Foundation Trust, Worthing, UK

Simon MattusDepartment of Paediatrics, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Slough, UK

Katie MckinnonDepartment of Paediatrics, North Middlesex University Hospital, London, UK

Philippa MikolajskiDepartment of Paediatrics, Oxford University Hospitals NHS Foundation Trust, Oxford, UK

Lottie MountDepartment of Community Paediatrics, Sussex Community NHS Foundation Trust, Brighton, UK

Maxine MurrayMedica Group, Hastings, UK

Karim NoordallyDepartment of Paediatrics, Oxford University Hospitals NHS Foundation Trust, Oxford, UK

Emily OpertoDepartment of Paediatrics, The Royal Brompton Hospital, London, UK

Kate ParkDepartment of Paediatric Radiology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK

Ashish PatelDepartment of Paediatric Nephrology, Birmingham Women’s and Children’s NHS Foundation Trust, Birmingham, UK

Rebecca PuddifootDepartment of Paediatrics, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Slough, UK

Sithara RamdasDepartment of Paedatrics, Oxford University Hospitals NHS Foundation Trust, Oxford, UK

Helen RatcliffeOxford Vaccine Group, Centre for Clinical Vaccinology and Tropical Medicine, Oxford, UK

Gillian RivlinDepartment of Paediatrics, Oxford University Hospitals NHS Foundation Trust, Oxford, UK

Claire RoomeDepartment of Paediatrics, Wexham Park Hospital, Frimley Health NHS Foundation Trust, Slough, UK

Tim SellDepartment of Paediatrics, Oxford University Hospitals NHS Foundation Trust, Oxford, UK

Domenico SiricoDepartment of Women’s and Children’s Health, Paediatric Cardiology Unit, Padua University Hospital, Padua, Italy

Andrew L. SmithDepartment of Paediatrics, Children’s Services, Homerton University Hospital NHS Foundation Trust, London, UK

Nicola J. SmithDepartment of Paediatrics, Oxford University NHS Foundation Trust, Oxford, UK

Eleni LoukaDepartment of Paediatric Haematology, Oxford University Hospitals NHS Foundation Trust, Oxford, UK

Dora SteelDepartment of Paediatrics, London School of Paediatrics, London, UK

Caroline TaylorDepartment of Paediatrics, Buckinghamshire Healthcare NHS Trust, Aylesbury, UK

Rachel VarugheseDepartment of Paediatrics, Oxford University Hospitals NHS Foundation Trust, Oxford, UK

Samantha WhiteDepartment of Paediatrics, Wexham Park Hospital, NHS Frimley Health Foundation Trust, UK

Jenny WoodruffDepartment of Paediatrics, Oxford University Hospitals NHS Foundation Trust, Oxford, UK

Acronyms and Abbreviations

AAT

alpha‐1‐antitrypsin

ABD

acute behavioural disturbance

ACE

angiotensin‐converting enzyme

AChR

acetylcholine receptor

ACS

acute chest syndrome

ACTH

adrenocorticotropic hormone

ADEM

acute demyelinating encephalomyelitis

AED

anti‐epileptic drug

AFP

alpha‐fetoprotein

AGN

acute glomerulonephritis

AIDS

acquired immunodeficiency syndrome

AIHA

autoimmune haemolytic anaemia

AIS

arterial ischaemic stroke

AKI

acute kidney injury

ALL

acute lymphoblastic leukaemia

ALP

alkaline phosphatase

ALT

alanine aminotransferase

ANA

antinuclear antibody

ANCA

antineutrophil cytoplasmic antibody

APTT

activated partial thromboplastin time

ARB

angiotensin receptor blocker

ARF

acute rheumatic fever

ASA

anterior spinal artery

ASD

atrial septal defect

ASOT

anti‐streptolysin O titre

AST

aspartate aminotransferase

AVM

arteriovenous malformation

AVNRT

AV nodal re‐entry tachycardia

AVRT

atrioventricular re‐entry tachycardia

AVSD

atrioventricular septal defect

BIMDG

British Inherited Metabolic Diseases Group

BiPAP

bilevel positive airway pressure

BMI

Body Mass Index

BNF

British National Formulary

BNP

B‐type natriuretic peptide

BP

blood pressure

BPPV

benign paroxysmal positional vertigo

BPVC

benign paroxysmal vertigo of childhood

BSPED

British Society for Paediatric Endocrinology and Diabetes

CAMHS

Child and Adolescent Mental Health Service

CF

cystic fibrosis

CFRD

cystic fibrosis–related diabetes

CFTR

cystic fibrosis transmembrane regulator

CGD

chronic granulomatous disease

CHD

congenital heart disease

CMPA

cow’s milk protein allergy

CMV

cytomegalovirus

CNS

central nervous system

COPD

chronic obstructive pulmonary disease

CPAP

continuous positive airway pressure

CPVT

catecholaminergic polymorphic ventricular tachycardia

CRH

corticotropin‐releasing hormone

CRP

C‐reactive protein

CSF

cerebrospinal fluid

CT

computed tomography

CVST

cerebral venous sinus thrombosis

DAT

direct antiglobulin test

DCM

dilated cardiomyopathy

DDH

developmental dysplasia of the hip

DI

diabetes insipidus

DIC

disseminated intravascular coagulation

DJ

duodenojejunal

DKA

diabetic ketoacidosis

DMSA

dimercaptosuccinic acid

DOT

directly observed therapy

dsDNA

double‐stranded DNA

DWI

diffusion‐weighted imaging

EBV

Epstein–Barr virus

ECG

electrocardiogram

ECMO

extracorporeal membrane oxygenation

EDS

Ehlers–Danlos syndrome

EEG

electroencephalogram

EM

erythema multiforme

ENT

Ear, Nose and Throat

ERCP

endoscopic retrograde cholangiopancreatography

ESR

erythrocyte sedimentation rate

ETN

erythema toxic neonatorum

FAOD

fatty acid oxidation defect

FBC

full blood count

FFA

free fatty acids

FFP

fresh frozen plasma

FHM

familial hemiplegic migraine

FII

fabricated or induced illness

FVC

forced vital capacity

γ‐GT

gamma‐glutamyltransferase

G6PD

glucose‐6‐phosphate dehydrogenase

GAL‐1‐PUT

galactose‐1‐phosphate uridyltransferase

GAS

group A

Streptococcus

GBS

group B

Streptococcus

GBS

Guillain–Barré syndrome

GCS

Glasgow Coma Scale

GGT

gamma‐glutamyltransferase

GI

gastrointestinal

GOR

gastro‐oesophageal reflux

GORD

gastro‐oesophageal reflux disease

GSD

glycogen storage disorders

GU

genitourinary

HACEK

Haemophilus,

Aggregatibacter

,

Cardiobacterium

,

Eikenella

,

Kingella

HbF

foetal haemoglobin

HCG

human chorionic gonadotropin

HCM

hypertrophic cardiomyopathy

HCT

haematocrit

HDU

high‐dependency unit

HHFNC

heated humidified high‐flow nasal cannula oxygen

HHS

hyperosmolar hyperglycaemic state

HHV

human herpesvirus

Hib

Haemophilus influenzae

type B

HIDA

hepatobiliary iminodiacetic acid

HIV

human immunodeficiency virus

HLA

human leucocyte antigen

HLH

haemophagocytic lymphohistiocytosis

HNIg

human normal immunoglobulin

HONK

hyperglycaemic hyperosmolar non‐ketotic coma

HPV

human papillomavirus

HR

heart rate

HS

hereditary spherocytosis

HSP

Henoch–Schönlein purpura

HSV

herpes simplex virus

HUS

haemolytic uraemic syndrome

HVA

homovanillic acid

IA

innominate artery

IBCLC

International Board Certified Lactation Consultant

IBD

inflammatory bowel disease

IBS

irritable bowel syndrome

ICD

implantable cardioverter‐defibrillator

ICP

intracranial pressure

IDA

iron‐deficiency anaemia

IEM

inborn errors of metabolism

Ig

immunoglobulin

IIH

idiopathic intracranial hypertension

ILCA

International Lactation Consultant Association

IM

intramuscular

INR

international normalised ratio

IOH

initial orthostatic hypotension

IST

inappropriate sinus tachycardia

ITP

immune thrombocytopenia

IUGR

intrauterine growth restriction

IV

intravenous

IVC

inferior vena cava

IVIg

intravenous immunoglobulin

JIA

juvenile idiopathic arthritis

JRA

juvenile rheumatoid arthritis

JVP

jugular venous pressure

LA

left atrium

LAIV

live attenuated influenza vaccine

LCCA

left common carotid artery

LDH

lactate dehydrogenase

LFTs

liver function tests

LMA

laryngeal mask airway

LMWH

low molecular weight heparin

LP

lumbar puncture

LQT

long QT

LSA

left subclavian artery

LV

left ventricle

LVH

left ventricular hypertrophy

LVOT

left ventricular outflow tract

MAHA

microangiopathic haemolytic anaemia

MAOI

monoamine oxidase inhibitor

MC&S

microscopy, culture and sensitivity

MCADD

medium‐chain acyl‐CoA dehydrogenase deficiency

MCHC

mean corpuscular haemoglobin concentration

MCUG

micturating cystourethrogram

MCV

mean corpuscular volume

MDT

multi‐disciplinary team

MELAS

mitochondrial myopathy, encephalopathy, lactic acidosis and stroke‐like episodes

MEN1

multiple endocrine neoplasia

MenB

meningococcal group B

MG

myasthenia gravis

MMR

measles, mumps, rubella

MODY

maturity‐onset diabetes of the young

MRCP

magnetic resonance cholangio pancreatogram

MRSA

methicillin‐resistant

Staphyloccocus aureus

MSH

melanocyte‐stimulating hormone

MSSA

methicillin‐sensitive

Staphylococcus aureus

NAC

N‐acetylcysteine

NAI

non‐accidental injury

NCSE

non‐convulsive status epilepticus

NDM

neonatal diabetes mellitus

NEAD

non‐epileptic attack disorder

NEC

necrotising enterocolitis

NG

nasogastric

NICE

National Institute for Health and Care Excellence

NJ

nasojejunal

NMS

neuroleptic malignant syndrome

NPA

naso‐pharyngeal aspirate

NSAIDs

non‐steroidal anti‐inflammatory drugs

NT‐proBNP

N‐terminal‐pro hormone BNP

OGD

oesophago‐gastro‐duodenoscopy

OH

orthostatic hypotension

OI

osteogenesis imperfecta

ORS

oral rehydration solution

PA

pulmonary artery

PaCO

2

partial pressure of carbon dioxide

PAC

premature atrial contraction

PAS

Paediatric Appendicitis Score

pCO

2

partial pressure of carbon dioxide

PCR

polymerase chain reaction

PCV

pneumococcal conjugate vaccine

PDA

patent ductus arteriosus

PE

pulmonary embolism

PEFR

peak expiratory flow rate

PEG‐J

percutaneous endoscopic transgastric jejunostomy