Clinical Small Animal Internal Medicine -  - E-Book

Clinical Small Animal Internal Medicine E-Book

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Beschreibung

Clinical Small Animal Internal Medicine is a comprehensive, practical reference designed to meet the needs of veterinary practitioners and students alike. Covering all aspects of small animal internal medicine, this innovative guide provides clinically relevant material, plus podcasts and continual updates online. Concise, identically-formatted chapters allow readers to quickly find the most essential information for clinical veterinary practice. Contributions from academic and clinical experts cover general medicine subjects, including patient evaluation and management, critical care medicine, preventative care, and diagnostic and therapeutic considerations. Topics relevant to daily clinical practice are examined in detail, ranging from endocrine, cardiovascular, respiratory, and infectious disease to oncology, dermatology, metabolic orthopedic disease, gastroenterology, and hepatology. A companion website features podcasts and updated information. An important addition to the library of any practice, this clinically-oriented text: * Presents complete, practical information on small animal internal medicine * Provides the background physiology required to understand normal versus abnormal in real-world clinical settings * Includes general medicine topics not covered in other internal medicine books * Focuses on information that is directly applicable to daily practice * Features podcasts and continual updates on a companion website Carefully tailored for the needs of small animal practitioners and veterinary students, Clinical Small Animal Internal Medicine is an invaluable, reader-friendly reference on internal medicine of the dog and cat.

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Veröffentlichungsjahr: 2020

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Table of Contents

Cover

Volume I

Preface

List of Contributors

About the Companion Website

Section 1: Evaluation and Management of the Patient

1 The Concept of One Medicine

Factors Driving One Health

The Human Domain

The Animal Domain

Role for Companion Animal Experts

Conclusion

Reference

2 Statistical Interpretation for Practitioners

External Validity

Internal Validity

Hypothesis Testing

Parametric versus Nonparametric Tests

Describing Data Distributions

Measures of Association and Effect

Incidence Odds and Incidence Odds Ratios

Conclusion

References

3 Using Data for Clinical Decision Making

Hospital‐Based Cross‐sectional Studies

Longitudinal Observational Studies

Conclusion

References

Section 2: Endocrine Disease

4 Principles of Endocrinology

Overview of Endocrinology

Chemical Classes of Hormones

Hormones in Circulation

Hormone Receptors

Regulation of Hormone Secretion

Endocrine Disease

Hormone Measurement

Further Reading

5 Neuroendocrinology

Anatomic Considerations of the Hypothalamus and Pituitary System

Regulation of the Neuroendocrine System

Vascular Supply

Regulation of Hormone Secretion

Further Reading

6 Feline Acromegaly

Etiology/Pathophysiology and Epidemiology

History and Clinical Signs

Diagnosis

Treatment

Conclusion

Further Reading

7 Pituitary‐Dependent Hyperadrenocorticism in Dogs and Cats

Etiology/Pathophysiology and Epidemiology

History and Clinical Signs

Diagnosis

Treatment

Prognosis

Further Reading

8 Polyuria and Polydipsia

Physiology of Water Metabolism

Etiology/Pathophysiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Further Reading

9 Canine Hypothyroidism

Etiology/Pathophysiology and Epidemiology

History and Clinical Signs

Diagnosis

Treatment

Prognosis

Further Reading

10 Feline Hyperthyroidism

Etiology/Pathophysiology and Epidemiology

History and Clinical Signs

Diagnosis

Treatment

Prognosis

Further Reading

11 Hypoadrenocorticism in Dogs and Cats

Hypoadrenocorticism in Dogs

Hypoadrenocorticism in Cats

Hyperaldosteronism in Cats

Further Reading

12 Diabetes Mellitus in Dogs and Cats

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis of Diabetes Mellitus

Therapy

Prognosis

Conclusion

Further Reading

13 Hypoglycemia in Patients without Diabetes Mellitus: Evaluation and Management

Maintenance of Normal Glucose Concentrations in Healthy Dogs and Cats

Clinical Signs of Hypoglycemia

Etiology/Pathophysiology

Diagnostic Approach to Disorders Associated with Hypoglycemia

Further Reading

14 Canine Autoimmune Polyglandular Syndromes

Etiology and Pathophysiology

History and Clinical Signs

Diagnosis and Prognosis

Therapy

Conclusion

Further Reading

Section 3: Cardiovascular Disease

15 Approach to the Patient with Suspected Cardiovascular Disease

Signalment

Case History and Owner Complaints

Physical Examination

16 Imaging in Cardiovascular Disease

Cardiac Radiography

Conventional Echocardiography

Conventional Doppler Echocardiography

Further Reading

17 Electrocardiography

Indications for ECG Recordings

ECG Lead Terminology and Acquisition Technique

Waveform Morphology and Intervals

Evaluation of the ECG

Criteria for Heart Enlargement

Conduction Abnormalities or Bundle Branch Block

Further Reading

18 Pathophysiology of Heart Failure

Components of the Circulatory System

Determinants of Normal Cardiac Function

The Failing Heart

Therapeutic Implications

Further Reading

19 Management of Heart Failure

Management of Chronic Heart Failure

Therapy for Refractory Chronic Heart Failure

Therapy of Acute Life‐Threatening Heart Failure

Further Reading

20 Ventricular Arrhythmias

Etiology/Pathophysiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

21 Supraventricular Arrhythmias

Sinus Bradycardia

Sick Sinus Syndrome (Sinus Node Dysfunction)

Persistent Atrial Standstill

Atrioventricular Block

Atrial Fibrillation

Other Forms of Supraventricular Tachyarrhythmia

Further Reading

22 Systemic Hypertension

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Further Reading

23 Pulmonary Hypertension

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Physical Examination

Diagnosis

Therapy

Prognosis

Further Reading

24 Congenital Heart Disease

Etiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Reference

Further Reading

25 Valvular Heart Disease

Canine Degenerative Myxomatous Mitral Valve Disease

Valvular Infectious Endocarditis

Further Reading

26 Canine Myocardial Disease

Dilated Cardiomyopathy

Arrhythmogenic Right Ventricular Cardiomyopathy

Hypertrophic Cardiomyopathy

Further Reading

27 Feline Myocardial Disease

Etiology

Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Further Reading

28 Pericardial Disease

Congenital

Pericardial Effusion

Constrictive Pericarditis

Further Reading

Section 4: Respiratory Disease

29 A Respiratory Pattern‐Based Approach to Dyspnea

Upper Airway

Lower Airway

Pleural Space

Pulmonary Parenchyma

Pulmonary Thromboembolism

Chest Wall

Diaphragm

Nonrespiratory Causes

Further Reading

30 Feline Bronchial Asthma

Etiology and Pathophysiology

Epidemiology

History and Clinical Signs

Diagnosis

Treatment

Prognosis

Further Reading

31 Canine Chronic Bronchitis

Etiology/Pathophysiology

Epidemiology

History and Clinical Signs

Diagnosis

Treatment

Prognosis

Further Reading

32 Pulmonary Thromboembolism

Pathophysiology

Clinical Signs

Diagnosis

Definitive Diagnostic Imaging

Management

Conclusion

Reference

Further Reading

33 Surgical Approaches to Thoracic Disease

Pathophysiology of Thoracotomy

Thoracostomy Tubes

Postoperative Monitoring

Postoperative Management

Further Reading

34 Pleural Effusion

Anatomy and Physiology

Pathophysiology of Pleural Fluid Accumulation

Clinical Signs and Physical Examination

Diagnostics

Pyothorax

Chylothorax

Hemothorax

Bilothorax

Conclusion

Further Reading

Section 5: Critical Care Medicine

35 Approach to the Patient in the Critical Care Setting

Physical Exam

History

Assessment

Record Keeping

Client Communication

Referral

The “Rule of 20”

Euthanasia

Conclusion

Further Reading

36 Fluid Therapy

Vascular Access

Body Fluid Compartments

Intravenous Fluid Types

Indications for Fluid Therapy

Monitoring of Fluid Therapy

Conclusion

Further Reading

37 Cardiopulmonary Resuscitation

Principles of CPR

Diagnosing Cardiopulmonary Arrest

Basic Life Support

Advanced Life Support

Defibrillation

Monitoring During CPR

Open Cardiac Massage

Postresuscitation Care

Discontinuing CPR

Further Reading

38 Respiratory Monitoring in Critical Care

Purpose

Identifying Respiratory Distress and Dyspnea

Determination of Response to Specific or Empiric Therapies

Assessment of the Adequacy of Alveolar Ventilation

Assessment of the Adequacy of Oxygenation

Evaluation of Gas Exchange Efficiency

Use of Pulmonary Mechanics to Categorize Disease

Conclusion

Further Reading

39 Acute Respiratory Failure

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Reference

Further Reading

40 Mechanical Ventilation

Indications for Mechanical Ventilation

Ventilator Settings

Mechanical Ventilation for Hypoxemic Respiratory Failure

Nursing Care for Ventilator Patients

Complications of Mechanical Ventilation

Nursing Care

Further Reading

41 Approach to the Patient with Shock

Pathophysiology of Shock and Effect on Organ Systems

Diagnosis

Classification of Shock

Oxygen Delivery

Treatment

Reevaluation and Endpoints of Resuscitation

Conclusion

Further Reading

42 Cardiogenic Shock

Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Further Reading

43 Septic Shock

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Treatment

Prognosis

Further Reading

44 Disorders of Heat and Cold

Normal Thermoregulation

Hypothermia

Hyperthermia

Fever

Heat Stroke

Further Reading

45 Acute Poisoning

History

Physical Examination

Clinical Approach

Decontamination

Conclusion

Further Reading

46 Medical Management of Trauma and Burns

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Further Reading

47 Venomous Snake Bites

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Conclusion

Further Reading

Section 6: Gastrointestinal Disease

48 Gastrointestinal Imaging

General Imaging Principles

The Pharynx

The Esophagus

The Stomach

Small Intestine

Large Intestine

Further Reading

49 Gastrointestinal Endoscopy

Endoscopy Equipment Options

Record Keeping for Endoscopy Procedures

Endoscope Handling

Endoscopic Terminology

Upper Gastrointestinal Endoscopy Procedures

Large Intestinal and Distal Small Intestinal Procedures

Endoscopic Biopsy Technique

Endoscopic Interventions

Future Directions of Gastrointestinal Endoscopy

Further Reading

50 Diseases of the Oral Cavity and Salivary Glands

Healthy Oral Tissues and Salivary Glands

Gingivitis and Periodontitis

Stomatitis

Odontogenic Tumors and Cysts

Malignant Melanoma

Squamous Cell Carcinoma

Eosinophilic Granuloma

Foreign Body

Immune‐Mediated and Autoimmune Diseases

Metabolic Disease

Burns

Salivary Gland Disease

Conclusion

Further Reading

51 Gastritis and Gastric Ulceration in Dogs and Cats

Normal Gastric Mucosal Barrier Function

Etiology and Pathophysiology of Gastritis

Epidemiology of Gastric Disease

History and Clinical Signs of Gastritis

Diagnostic Approach to Suspected Gastritis

Treatment of Gastritis and Gastric Ulceration

Prognosis

Further Reading

52 Disorders of the Esophagus

Normal Esophageal Anatomy and Physiology

Recognition of Esophageal Disorders

Diagnostic Approach to Esophageal Disease

Specific Esophageal Disorders

Esophagitis

Esophageal Strictures

Esophageal Foreign Bodies

Vascular Ring Anomalies

Further Reading

53 Motility Disorders of the Alimentary Tract

Motility Disorders of the Esophagus

Motility Disorders of the Stomach

Motility Disorders of the Small Intestine

Motility Disorders of the Large Intestine

Prokinetics

Further Reading

54 Exocrine Pancreatic Insufficiency in Dogs and Cats

Pathogenesis

Etiology

Signalment

Clinical Features

Diagnosis

Treatment

Prognosis

Further Reading

55 Pancreatitis in the Dog

Etiology/Pathophysiology

Epidemiology

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Conclusion

Further Reading

56 Pancreatitis in the Cat

Clinical Signs and Symptoms of Pancreatitis in Cats

Noninvasive Diagnostics for Feline Pancreatitis

Approaches to Management of Pancreatitis in Cats

Complications of Pancreatitis in Cats

Further Reading

57 Rectoanal Diseases – Medical and Surgical Management

Anal Sac Adenocarcinoma

Anal Sac Impaction

Atresia Ani and Rectoanal Strictures

Constipation, Obstipation, and Megacolon

Perianal Fistulae

Pseudocoprostasis

Rectal Foreign Bodies

Rectal Polyps

Rectal Prolapse

Rectal Tears and Trauma

Rectal Tumors

Further Reading

58 Dysbiosis and the Use of Pre‐, Pro‐ and Synbiotics

The Importance of the Gastrointestinal Microbiota

The Gastrointestinal Microbiota in Healthy Dogs and Cats

The Gastrointestinal Microbiota in Disease

Therapeutic Approach to Dysbiosis

Clinical Data on Probiotics in Veterinary Medicine

Further Reading

59 Diagnosis and Management of Chronic Enteropathies

Definition

Classification of Chronic Enteropathies

Etiopathogenesis

Epidemiology

History, Clinical Signs, and Diagnostic Work‐Up

Serum and Fecal Markers of Disease

Work‐up and Diagnostic Tests: Abdominal Ultrasound, Endoscopy, and Histopathology

Treatment and Prognosis

Further Reading

Section 7: Diseases of the Liver, Gallbladder, and Bile Ducts

60 Approach to the Patient with Liver Disease

Pathophysiology of Important Clinical Presentations of Liver Disease

Signalment

History and Clinical Signs

Diagnosis

Conclusion

Further Reading

61 Imaging in Hepatobiliary Disease

Classification of Hepatobiliary Disease

Normal Hepatobiliary Anatomy

Hepatobiliary Radiography

Hepatobiliary Ultrasonography

Imaging Features of Hepatobiliary Disease

Advanced Imaging Techniques

Image‐Guided Sampling

Further Reading

62 Metabolic, Toxic, and Neoplastic Diseases of the Liver

Metabolic Diseases

Toxic Diseases

Neoplasia

Further Reading

63 Feline Inflammatory Liver Disease

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Further Reading

64 Canine Inflammatory Liver Disease

Chronic Hepatitis

Acute Hepatitis

Further Reading

65 Cirrhosis and its Consequences

Etiology/Pathophysiology

Signalment

History and Clinical Signs

Diagnosis

Treatment

Monitoring

Prognosis

Conclusion

Further Reading

66 Portosystemic Shunts and Microvascular Dysplasia

Etiology

Pathophysiology

Epidemiology

Diagnosis

Therapy

Prognosis

Further Reading

67 Diseases of the Gallbladder and Extrahepatic Biliary Ducts

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Further Reading

Section 8: Neurologic Disease

68 The Neurologic Examination

Anatomic Diagnosis

Examination

Further Reading

69 Central Nervous System Trauma

Spinal Trauma

Head Trauma

70 Seizures and Movement Disorders

Seizures

Movement Disorders

Further Reading

71 Disorders of the Forebrain

Anatomy/Function

Etiology/Pathophysiology

Degenerative and Developmental Causes

Anomalous Causes

Metabolic Causes

Neoplastic Causes

Nutritional Causes

Inflammatory/Idiopathic Causes

Vascular Causes

72 Vestibular Disease

Peripheral versus Central Disease

Etiology

Further Reading

73 Meningoencephalitis and Meningomyelitis

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Further Reading

74 Diseases of the Neuromuscular Junction

Myasthenia Gravis

Other Disorders of Neuromuscular Transmission

Further Reading

75 Myopathies

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Resources

Further Reading

76 Myelopathy

History

Pathophysiology

Clinical Signs

Acute Spinal Cord Dysfunction

Diagnostic Approach

Differential Diagnosis

Treatment

Further Reading

77 Neuroophthalmology

Amaurosis

Optic Neuritis

Anisocoria

Internal and External Ophthalmoplegia

Trigeminal Nerve Deficit

Facial Nerve Paralysis

Horner's Syndrome

Cavernous Sinus Syndrome

Dysautonomia (Key–Gaskell or Dilated Pupil Syndrome)

Further Reading

Volume II

Preface

List of Contributors

About the Companion Website

Section 9: Infectious Disease

Part 1: Diagnostic Considerations

78 Epidemiology of Infectious Disease

Disease Monitoring and Surveillance

Outbreak Investigations

Step 6: Communicate Findings

Conclusion

Further Reading

79 Laboratory Diagnosis of Infectious Diseases

Protozoal and Arthropod‐Borne Infections

Viral Infections

Bacterial Infections

Fungal Infections

Further Reading

Part 2: Select Infectious Diseases and Disease Agents

80 Canine Distemper

Etiology/Pathophysiology

Epidemiology

Signalment

Clinical Signs

Diagnosis

Treatment

Prevention

Prognosis

Public Health Implications

Further Reading

81 Canine Herpesvirus

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Public Health Implications

Further Reading

82 Canine Viral Enteritis

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Prevention

Public Health Implications

Further Reading

83 Viral Papillomatosis

Etiology/Pathophysiology

Epidemiology

Signalment

Clinical Signs

Diagnosis

Therapy and Prognosis

Prevention

Public Health Implications

Further Reading

84 Canine Influenza Virus

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Public Health Implications

Further Reading

85 Feline Parvovirus

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Treatment

Prognosis

Prevention

Public Health Implications

Further Reading

86 Feline Coronavirus

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Prevention

Public Health Implications

Further Reading

87 Feline Leukemia Virus

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Treatment

Prognosis

Prevention and Control

Public Health Implications

Further Reading

88 Feline Immunodeficiency Virus

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Management

Prognosis

Public Health Implications

Further Reading

89 Feline Viral Upper Respiratory Tract Disease

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Prevention

Public Health Significance

Further Reading

90 Rabies in Dogs and Cats

Etiology and Pathophysiology

Epidemiology

Signalment

History

Clinical Signs

Diagnosis

Therapy

Prognosis

Prevention

Public Health Implications

Further Reading

91 West Nile Virus

Etiology/Pathophysiology

Epidemiology

Signalment

Diagnosis

Therapy

Prognosis

Public Health Implications

Further Reading

92 Ebola Virus

Etiology/Pathophysiology

Epidemiology

Clinical Signs

Diagnosis

Therapy

Prognosis

Public Health Implications

Further Reading

93 Ehrlichiosis and Anaplasmosis

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Public Health Implications

Further Reading

94 Salmon Poisoning Disease

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Public Health Implications

Further Reading

95

Wolbachia pipientis

Infection

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Public Health Implications

Further Reading

96 Bartonellosis

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Public Health Implications

Further Reading

97 Hemotropic

Mycoplasma

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Public Health Implications

Further Reading

98 Nonhemotropic

Mycoplasma

,

Ureaplasma

, and L‐Form Bacteria

Etiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Public Health Implications

Further Reading

99 Spotted Fever and Typhus Group Rickettsia

Etiology/Pathophysiology

Epidemiology

Signalment

Diagnosis

Therapy

Prognosis

Public Health Implications

Further Reading

100 Lyme Borreliosis

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Prevention

Public Health Implications

Further Reading

101 Leptospirosis

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Vaccination

Public Health Implications

Further Reading

102 Yersiniosis

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Prevention

Public Health Implications

Further Reading

103 Tularemia

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Public Health Implications

Further Reading

104 Q Fever

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Public Health Implications

Further Reading

105 Brucellosis

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Public Health Implications

Further Reading

106 Tetanus and Botulism

Tetanus

Botulism

Further Reading

107 Anthrax

Etiology/Pathophysiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Public Health Implications

Prevention

Further Reading

108 Actinomycosis, Nocardiosis, and Mycobacterial Infections

Actinomycosis

Nocardiosis

Mycobacteriosis

Further Reading

109 Fungal Infections

General Features of Fungal Infections

Dermatophytosis

Malassezia

Infections

Blastomycosis

Histoplasmosis

Cryptococcosis

Coccidioidomycosis

Aspergillosis

Candidiasis

Sporotrichosis

Miscellaneous Fungus‐Like Infections (Pythiosis and Rhinosporidiosis)

Further Reading

110 Protozoal and Protozoa‐Like Infections

Toxoplasmosis

Neosporosis

Trypanosomiasis

Leishmaniosis

Hepatozoonosis

Feline Cytauxzoonosis

Babesiosis

Giardiasis

Miscellaneous Infections

Selected Reading and References

111 Coccidia

Cystoisospora

spp.

Cryptosporidium

spp.

Microspora

Further Reading

112 Surgical, Traumatic, and Bite Wound Infections

Surgical and Traumatic Wound Infections

Bite Wounds

Further Reading

113 Canine Infectious Respiratory Disease Complex

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy and Prevention

Prognosis

Public Health Implications

Conclusion

Further Reading

Part 3: Therapeutic Considerations

114 Antimicrobial Therapy in Dogs and Cats

Common Classes of Antimicrobials

Further Reading

115 Antifungal Therapy

Amphotericin B

Azoles

Echinocandins

Terbinafine

Further Reading

Part 4: Special Topics

116 Nosocomial and Multidrug‐Resistant Infections

Identification of Hospital‐Associated Infections

Common Presentations and Risk Factors for HAIs

Pathogens of Concern

Management

Conclusion

Further Reading

117 Management of Infectious Disease in Kennels and Multicat Environments: Creating a Culture of Compliance

Risks

Modes of Transmission

Prevention

Vaccination

Cleaning and Disinfection

Managing Outbreaks

Culture of Compliance

Protection from Zoonotic Pathogens

Conclusion

Further Reading

Section 10: Renal and Genitourinary Disease

118 Disorders of Sodium and Water Homeostasis

Water Balance Made Easy

Sodium and Water Disturbances: A Little Physiology Goes a Long Way

Osmoregulation and Volume Regulation

Hyponatremia

Hypernatremia

Conclusion

Further Reading

119 Disorders of Phosphorus and Magnesium

Phosphorus

Magnesium

Further Reading

120 Acute Kidney Injury

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Further Reading

121 Glomerular Disease

Etiology/Pathophysiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Further Reading

122 Obstructive Uropathy

Urethral Obstruction

Ureteral Obstruction

Further Reading

123 Urolithiasis in Small Animals

Overview

History and Physical Examination

Patient Signalment Related to Specific Stone Types

Urolith Diagnosis

Medical Management of Lower Urinary Tract Stones

Removal of Lower Urinary Tract Uroliths

Removal of Upper Urinary Tract Uroliths

Further Reading

124 Prostatic Diseases

Benign Prostatic Hyperplasia and Prostatic Cysts

Paraprostatic Cysts

Prostatitis and Prostatic Abscesses

Squamous Metaplasia of Prostatic Epithelial Cells

Further Reading

125 Management of Chronic Kidney Disease

Disease Staging

Medical Management of Chronic Kidney Disease

Monitoring CKD Patients

Prognosis

Further Reading

126 The Role of Dialysis

Dialysis Modalities

Dialysis for Acute Kidney Injury

Fluid Overload/Oliguria/Anuria

Dialysis for Chronic Kidney Disease

Alternative Indications for Dialysis: Acute Intoxications and Therapeutic Plasma Exchange

Availability of Dialysis and Prognosis for Dialysis Patients

Further Reading

127 Micturition and Associated Disorders

Physiology of Micturition

Disorders of Storage

Disorders of Emptying

Further Reading

128 Urinary Tract Infections

Etiology/Pathophysiology

Epidemiology/Signalment

History and Clinical Signs

Diagnosis

Classification of Urinary Tract Infections

Therapy

Prognosis

Further Reading

Section 11: Oncologic Disease

129 Approach to the Cancer Patient

Initial Assessment

Diagnostics

Therapy

End‐of‐Life Management

Further Reading

130 Biology of Cancer and Cancer Genetics

Enabling Replicative Immortality

Evading Growth Suppressors

Resisting Cell Death

Genome Instability and Mutation

Tumor Promoting Inflammation

Avoiding Immune Destruction

Inducing Angiogenesis

Sustaining Proliferative Signaling

Deregulating Cellular Energetics

Activating Invasion and Metastasis

Conclusion

Further Reading

131 Endocrine Manifestations of Cancer: Ectopic Hormone Production

Cushing Syndrome

Syndrome of Inappropriate Antidiuretic Hormone Secretion

Erythrocytosis

Zollinger–Ellison Syndrome

Further Reading

132 Paraneoplastic Syndromes

Hypercalcemia

Hypoglycemia

Anemia/Thrombocytopenia

Hypertrophic Osteopathy

Myasthenia Gravis

Superficial Necrolytic Dermatitis

Paraneoplastic Alopecia

Conclusion

Further Reading

133 Lymphoid Leukemias, Myeloid Neoplasia, and Myelodysplastic Syndrome

Lymphoid Leukemias

Myeloid Neoplasia

Myelodysplastic Syndromes

Further Reading

134 Lymphomas

Canine Lymphoma

Feline Lymphoma

Conclusion

Further Reading

135 Plasma Cell Disorders

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Further Reading

136 Central Nervous System Tumors in Dogs and Cats

Etiology/Epidemiology/Signalment

History and Clinical Signs

Diagnosis

Treatment/Prognosis

Further Reading

137 Cancer of the Nose and Mouth

Oral Tumors

Nasal Tumors

Cancer of the Pharynx

Further Reading

138 Tumors of the Eye and Ocular Adnexa

Tumors of the Ocular Adnexa

Intraocular Tumors

Tumors of the Orbit and Optic Nerve

Further Reading

139 Cancer of the Heart

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Further Reading

140 Cancer of the Airway and Lung

Cancer of the Airway

Cancer of the Lung

Further Reading

141 Cancer of the Esophagus and Stomach

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Further Reading

142 Cancer of the Small and Large Intestine

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Further Reading

143 Exocrine Pancreatic Cancer

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Further Reading

144 Pancreatic Endocrine Tumors

Insulinoma

Glucagonoma

Gastrinoma

Further Reading

145 Liver and Biliary Tract Tumors

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy and Prognosis

Further Reading

146 Tumors of the Urinary Tract

Tumors of the Urinary Bladder

Urethral Tumors

Renal Tumors

Further Reading

147 Tumors of the Male Reproductive System

Testicular Tumors

Prostate Tumors

Penis, Prepuce, and Scrotum Tumors

Transmissible Venereal Tumor

Further Reading

148 Gynecologic Cancers

Uterine Tumors

Vaginal Tumors

Ovarian Tumors

Further Reading

149 Mammary Cancer

Canine Mammary Cancer

Feline Mammary Cancer

Further Reading

150 Tumors of Bone and Joint

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Further Reading

151 Soft Tissue Sarcomas

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Further Reading

152 Hemangiosarcoma

Etiology and Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Staging System

Therapy

Prognosis

Further Reading

153 Melanoma

Etiology/Pathophysiology/Epidemiology

Signalment

Diagnosis/Pathology/Molecular Biology

Staging

Therapy

Prognosis

Further Reading

154 Nonmelanoma Skin Cancers

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Further Reading

155 Mast Cell Neoplasia

Etiology/Pathophysiology

Canine Mast Cell Neoplasia

Feline Mast Cell Tumors

Further Reading

156 Apheresis in Companion Animals

Cell Separator Machines

Physician‐Based Applications of Apheresis

Companion Animal Apheresis

Conclusion

Further Reading

Section 12: Skin and Ear Diseases

157 Approach to the Patient with Dermatologic Disease

History

Physical Examination

Dermatologic Diagnostic Tests and Techniques

Therapeutic Plan and Client Education

Further Reading

158 Principles of Therapy of Dermatologic Diseases

Topical Therapy

Systemic Therapy

Categories and Indications of Topical and Systemic Therapy

Further Reading

159 Atopic Dermatitis

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Conclusion

Further Reading

160 Allergic Skin Diseases

Urticaria and Angioedema

Allergic Contact Dermatitis

Flea Allergy Dermatitis

Further Reading

161 Cutaneous Adverse Food Reactions

Etiology/Pathophysiology

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Further Reading

162 Autoimmune and Immune‐Mediated Skin Diseases

Canine Familial Dermatomyositis

Erythema Multiforme

Toxic Epidermal Necrolysis

Cutaneous Lupus Erythematosus

Autoimmune Subepidermal Blistering Diseases

Pemphigus Complex

Uveodermatologic Syndrome

Further Reading

163 Approach to Alopecia

Etiology/Pathophysiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Further Reading

164 Canine Sterile Papular and Nodular Skin Diseases

Canine Histiocytic Disorders

Sterile Nodular Panniculitis

Sterile Granuloma/Pyogranuloma Syndrome

Juvenile Cellulitis

Further Reading

165 Parasitic Skin Diseases

Demodicosis

Scabies

Cheyletiellosis

Lynxacarus radovsky

Dermanyssus gallinae

Pediculosis

Trombiculosis

Ticks

Further Reading

166 Bacterial Pyodermas

Etiology/Pathophysiology

Pyoderma Classifications and Presentations

Methicillin‐Resistant and Multidrug‐Resistant Staphylococci

Treatment of Pyodermas

Further Reading

167 Otitis

Otitis Externa

Otitis Media

Further Reading

168 Cutaneous Manifestations of Systemic Disease

Hormonal and Metabolic Disorders Causing Cutaneous Manifestations

Systemic Infectious Disease Causing Cutaneous Manifestations

Nutritional Disorders Causing Cutaneous Manifestations

Immune‐Mediated Systemic Diseases Causing Cutaneous Manifestations

Neurologic Disorders Causing Cutaneous Manifestations

Neoplastic and Paraneoplastic Disorders Affecting the Skin

Further Reading

169 Superficial Necrolytic Dermatitis

Etiology/Pathophysiology

Signalment

Clinical Signs

Diagnosis

Therapy

Prognosis

Further Reading

170 Miscellaneous Skin Diseases

Sebaceous Adenitis

Eosinophilic Dermatitis

Sterile Neutrophilic Dermatosis

Ichthyosis

Eosinophilic Granuloma Complex

Symmetric Lupoid Onychitis (Symmetric Lupoid Onychodystrophy)

Further Reading

Section 13: Diseases of Bone and Joint

171 Skeletal Development and Homeostasis

Skeletal Development and Growth

Bone Morphology

Bone Physiology

Bone Pathophysiology

Complications with Fracture Healing – Delayed Union, Malunion, and Nonunion

Further Reading

172 Metabolic Bone Diseases

Calcium and Phosphorus Physiology

Fibrous Osteodystrophy

Rickets and Osteomalacia

Osteoporosis

Further Reading

173 Osteoarthritis in Small Animals

Etiology/Pathophysiology

Epidemiology

Signalment

History and Clinical Signs

Diagnosis

Therapy

Prognosis

Further Reading

174 Developmental Orthopedic Diseases

Developmental Orthopedic Diseases Affecting Joints

Developmental Orthopedic Diseases Affecting Bone

Further Reading

Section 14: Social and Ethical Issues in Veterinary Medicine

175 Canine and Feline End of Life Care

Veterinary Palliative Medicine and Hospice Care

Evaluating and Maintaining Quality of Life in End of Life Care

Pets Should Not Suffer to Death

The Four Foundational Principles of Clinical Bioethics

Bioethical Principles and The Life‐Limited Pet

End of Life Care and The Human–Animal Bond

Conclusion

Further Reading

Section 15: Preventive Care

176 Role of Immunization

Antigen Delivery Systems

Vaccine Failures

Conclusion

Further Reading

Vaccine Recommendations

177 Behavior Triage for Internists and the General Practitioner

Behavioral Presentations

Behavioral Triage

Referrals

Safety and Avoidance: Short‐Term Recommendations

Managing Client Expectations

Conclusion

Further Reading

Websites

Section 16: Laboratory Support

Index

End User License Agreement

List of Tables

Chapter 2

Table 2.1 Commonly used parametric and equivalent nonparametric statistical t...

Chapter 5

Table 5.1 Hypothalamic‐pituitary hormones and their primary functions

Chapter 7

Table 7.1 Diagnostic tests to evaluate patients with suspected PDH

Table 7.2 Diagnostic tests that differentiate between PDH and ADH

Chapter 8

Table 8.1 Currently available DDAVP preparations and common dosages

Chapter 10

Table 10.1 Advantages/disadvantages of options for managing cats with hyperth...

Chapter 12

Table 12.1 Effects of insulin and counterregulatory hormones on carbohydrate ...

Table 12.2 Insulin types used in companion animal medicine and their characte...

Chapter 15

Table 15.1 Classification of murmur intensity

Table 15.2 Simplified table for presumptive diagnosis of murmur origin in com...

Chapter 16

Table 16.1 Main noncardiac‐related factors able to induce cardiac silhouette ...

Table 16.2 Examples of vertebral heart score (VHS) values assessed on lateral...

Table 16.3 Generalized or localized heart enlargement on thoracic radiographs...

Table 16.4 Standard echocardiographic and pulsed‐wave Doppler data obtained f...

Table 16.5 Standard echocardiographic and pulsed‐wave Doppler echocardiograph...

Chapter 17

Table 17.1 The positive and negative terminals of the six limb leads

Table 17.2 Electrode position for ECG recording in dogs and cats

Table 17.3 Normal ECG amplitudes and durations in the dog and cat

Table 17.4 ECG criteria for heart enlargement in the dog and cat

Chapter 19

Table 19.1 Commonly used drugs for the treatment of chronic heart failure

Table 19.2 Commonly used drugs for the treatment of acute heart failure

Chapter 20

Table 20.1 Typical medication doses

Chapter 21

Table 21.1 Differential diagnosis of supraventricular arrhythmias

Table 21.2 Drug dosages and indications

Chapter 22

Table 22.1 Evidence of target organ damage. Clinical signs of target organ da...

Chapter 24

Table 24.1 Breed predilection of common congenital heart defects in the dog

Table 24.2 An auscultation rubric, the six Ss, for evaluation of a left basil...

Chapter 25

Table 25.1 Classification system for dogs affected by myxomatous mitral valve...

Chapter 26

Table 26.1 Echocardiographic parameters in normal dogs and breed‐specific cri...

Table 26.2 Doses of commonly used cardiac medications in dogs (see text for i...

Chapter 29

Table 29.1 Common diseases affecting the upper airway

Table 29.2 Areas evaluated during tFAST

3

and VetBLUE examination

Table 29.3 Common etiologies based on thoracic radiographic patterns of distr...

Chapter 32

Table 32.1 Recognized risk factors for PTE disease processes with a known ass...

Chapter 34

Table 34.1 Starling Law applied to pleural membrane

Table 34.2 Causes of pleural effusion in dogs and cats

Table 34.3 Classification of effusions in dogs and cats

Table 34.4 Pyothorax bacterial isolates

Chapter 38

Table 38.1 Blood gas analysis reference intervals

Chapter 39

Table 39.1 Approximate flow rates of 100% oxygen via nasal cannulae required ...

Chapter 41

Table 41.1 Dosages of commonly used opioid analgesics in the patient with sho...

Chapter 43

Table 43.1 SIRS criteria for dogs and cats

Chapter 48

Table 48.1 Common imaging findings assessed using ultrasound, contrast radiog...

Table 48.2 Useful guidelines for evaluating the normal small intestinal diame...

Chapter 49

Table 49.1 Terminology used for the description of endoscopically visualizabl...

Chapter 50

Table 50.1 Nomenclature of oral and oropharyngeal inflammation according to t...

Chapter 51

Table 51.1 Causes of gastritis in dogs and cats

Table 51.2 Causes of gastric ulceration in dogs and cats

Table 51.3 Commonly used medications for canine and feline gastritis

Chapter 53

Table 53.1 Methods to assess gastric emptying in small animals and their diag...

Table 53.2 Mechanism and site of action, dosages and important clinical infor...

Table 53.3 Treatments for chronic idiopathic large bowel disease (CILBD)

Chapter 54

Table 54.1 Treatment options for dogs and cats with exocrine pancreative insu...

Chapter 55

Table 55.1 Classification of clinical signs into severity categories

Table 55.2 Summary of sensitivity and specificity for various laboratory test...

Chapter 56

Table 56.1 Historical and clinical findings in cats with confirmed pancreatic...

Table 56.2 Medications commonly used in the management of severe pancreatitis...

Chapter 57

Table 57.1 Drugs commonly used in the management of rectoanal disease in the ...

Chapter 59

Table 59.1 Differentiation of small intestinal and large intestinal diarrhea ...

Chapter 60

Table 60.1 Typical examples of use of pattern recognition in clinical patholo...

Chapter 63

Table 63.1 Antibacterial agents used in the management of feline hepatobiliar...

Table 63.2 Supportive therapies used in the management of feline hepatobiliar...

Chapter 64

Table 64.1 Age and gender data for breeds with an increased risk for developi...

Chapter 66

Table 66.1 Clinical and diagnostic features of different conditions causing b...

Chapter 69

Table 69.1 Analgesic drugs suggested for use in patients with spinal cord inj...

Table 69.2 Advantages and disadvantages of different stabilization techniques

Table 69.3 Monitoring parameters for the cat and dog following head trauma

Table 69.4 Modified Glasgow Coma Scale

Chapter 70

Table 70.1 Summary of antiepileptic drug therapy in the dog

Chapter 71

Table 71.1 Clinical signs of forebrain disease

Chapter 73

Table 73.1 Infectious agents causing meningoencephalomyelitis in small animal...

Table 73.2 Presumed noninfectious inflammatory central nervous system (CNS) c...

Table 73.3 Antimicrobial medications for meningoencephalitis and meningomyeli...

Table 73.4 Antiinflammatory and immunosuppressive medications for meningoence...

Chapter 76

Table 76.1 Differential diagnosis for acute‐onset myelopathy

Table 76.2 Differential diagnosis for chronic myelopathy

Table 76.3 Neurologic signs associated with spinal cord regions

Chapter 79

Table 79.1 Advantages and disadvantages of common diagnostic methods for the ...

Table 79.2 Collection, processing, and transport recommendations for differen...

Chapter 82

Table 82.1 Comparison of CPV‐2 and other canine enteric viruses

Chapter 83

Table 83.1 Papillomavirus‐associated disease in domestic dogs and cats

Chapter 93

Table 93.1 Species of

Ehrlichia

and

Anaplasma

of importance to dogs and cats

Table 93.2 Main features of ehrlichiosis and anaplasmosis in dogs

Table 93.3 Features of diagnostic assays available for ehrlichiosis and anapl...

Chapter 96

Table 96.1 Species of

Bartonella

detected in dogs, cats, and other hosts

Table 96.2 Average bacteremia level found in immunocompetent cats, dogs, and ...

Chapter 97

Table 97.1 Hemoplasma species, their prevalence and pathogenicity

Chapter 98

Table 98.1 Nonhemotropic mycoplasmas frequently isolated from domestic dogs a...

Chapter 107

Table 107.1 Anthrax severity in potentially affected species

Table 107.2

In vitro

antimicrobial susceptibility of

B. anthracis

Chapter 108

Table 108.1 Antimicrobials used to treat

Actinomyces

and

Nocardia

infections

Table 108.2  Mycobacteria spp. and their manifestations in dogs and cats

Table 108.3 Antimicrobials used to treat mycobacterial infections

Chapter 111

Table 111.1 Enteric coccidia of the dog and cat

Table 111.2 Treatment of enteric coccidiosis in dogs and cats

Chapter 114

Table 114.1 Classes of antimicrobials used in small animal veterinary medicin...

Table 114.2 Clinically important side‐effects and drug–drug interactions asso...

Chapter 115

Table 115.1 Summary of azole antifungal drugs, including formulation, indicat...

Chapter 118

Table 118.1 Categories of hyponatremia

Table 118.2 Syndrome of inappropriate ADH secretion summary

Table 118.3 Causes of hypernatremia

Chapter 120

Table 120.1 List of etiologies for canine and feline acute kidney injury

Table 120.2 Veterinary Acute Kidney Injury (VAKI) staging scheme for dogs

Table 120.3 International Renal Interest Society grading scheme for acute kid...

Table 120.4 Indications, doses, adverse effects, and comments for drugs frequ...

Chapter 121

Table 121.1 Select breeds of dogs with familial glomerulopathies

Table 121.2 International Renal Interest Society substaging by arterial blood...

Chapter 122

Table 122.1 Emergency dosing for severe hyperkalemia. All medications given i...

Chapter 123

Table 123.1 Summary of the signalment of cats and dogs with each type of ston...

Table 123.2 Urolith composition for feline and canine samples submitted to th...

Table 123.3 Compound urolith recurrence prevention strategies. The strategy f...

Table 123.4 Considerations for various interventional procedures in patients ...

Table 123.5 Immediate, short‐term, and long‐term complications of various min...

Chapter 124

Table 124.1 Procedures for collecting cytologic samples from the prostate

Table 124.2 Antibiotics used for bacterial prostatitis

Chapter 125

Table 125.1 IRIS chronic kidney disease stages in cats and dogs

Table 125.2 Classification of proteinuria in cats and dogs

Table 125.3 Classification of blood pressure in cats and dogs

Table 125.4 Recommended serum phosphorus concentrations at each IRIS stage

Chapter 127

Table 127.1 Commonly used medical therapies for urethral sphincter mechanism ...

Chapter 128

Table 128.1 Commensal bacterial genera in the urogenital tract of dogs

Table 128.2 Quantitative urine cultures in dogs and cats

a

Chapter 133

Table 133.1 Recommended immunophenotyping markers to differentiate animal leu...

Chapter 134

Table 134.1 World Heath Organization clinical staging scheme for lymphoma in ...

Table 134.2 UW‐Madison short CHOP lymphoma protocol

Table 134.3 Modified COP protocol for treatment of feline lymphoma

Chapter 135

Table 135.1 Frequency of abnormal diagnostic test results in dogs and cats wi...

Chapter 136

Table 136.1 Summary of outcomes of dog and cats with brain neoplasia

Chapter 137

Table 137.1 WHO staging system for oral tumors

Table 137.2 Adams 2009 modified staging system for canine nasal tumors

Chapter 140

Table 140.1 Prognostic factors and associated median survival times for dogs ...

Chapter 149

Table 149.1 Canine mammary tumor staging. Modified World Health Organization ...

Table 149.2 Feline mammary tumor staging. Modified World Health Organization ...

Chapter 150

Table 150.1 Treatment options for canine appendicular osteosarcoma

Chapter 152

Table 152.1 Modified World Health Organization TNM staging system

Table 152.2 Chemotherapeutics commonly used for the treatment of hemangiosarc...

Chapter 155

Table 155.1 CVP combination protocol as initially noted in Rassnick

et al

.

Table 155.2 Alternating lomustine and vinblastine protocol as initially noted...

Chapter 157

Table 157.1 Common skin diseases in various breeds

Table 157.2 Terminology used to describe lesion morphology

Table 157.3 Regional predilections of skin diseases

Chapter 160

Table 160.1 Possible factors for triggering urticaria and angioedema in dogs ...

Chapter 161

Table 161.1 Ingredients reported to cause adverse food reaction (AFR) in dogs...

Chapter 162

Table 162.1 Immunosuppressive drug therapy

Chapter 163

Table 163.1 Differential diagnoses for inflammation‐induced alopecia

Table 163.2 Common breeds associated with noninflammatory alopecic syndromes ...

Table 163.3 Treatment options for select inflammation‐induced alopecic condit...

Chapter 167

Table 167.1 Secondary causes in otitis externa

Table 167.2 Cytologic findings and interpretation

Table 167.3 Selection of ear cleaner based on the type of discharge present

Table 167.4 Topical antibiotic therapy for use in otitis externa and media

Table 167.5 Systemic glucocorticoid therapy for use in otitis externa and med...

Table 167.6 Systemic antibiotic therapy for use in otitis media

Chapter 171

Table 171.1 Epiphyseal growth center appearance and growth plate fusion of se...

Chapter 174

Table 174.1 Breed predispositions for selected developmental orthopedic disea...

Table 174.2 Manifestations of osteochondrosis

Chapter 175

Table 175.1 Villalobos Quality of Life (HHHHHMM) Scale

List of Illustrations

Chapter 2

Figure 2.1 Histogram showing a hypothetical asymmetric data distribution. Th...

Figure 2.2 Box and whiskers plot for data shown in Figure 2.1. Lower and upp...

Figure 2.3 Scatterplots showing before and after measurements taken on five ...

Chapter 3

Figure 3.1 Rate of cure illustrated in a Kaplan–Meier plot.

Chapter 4

Figure 4.1 Fluctuations in levels of cortisol and T4 in a healthy dog during...

Figure 4.2 Low‐dose dexamethasone (Dex) suppression patterns in dogs. Admini...

Chapter 5

Figure 5.1 Schematic representation of the hypothalamus and pituitary gland. ...

Figure 5.2 Schematic representation of proopiomelanocortin (POMC) and produc...

Figure 5.3 Typical feedback control of hormone secretion in the neuroendocri...

Chapter 11

Figure 11.1 A 13‐year‐old male neutered domestic shorthair presented for acu...

Chapter 12

Figure 12.1 Diabetic cataracts in a dog. (a) An 11‐year‐old cross‐bred dog p...

Figure 12.2 Cat with plantigrade stance.

Chapter 15

Figure 15.1 Principal areas of cardiac auscultation in dogs. The valve relat...

Chapter 16

Figure 16.1 Lateral thoracic radiograph of an obese dog. The cardiac silhoue...

Figure 16.2 Lateral thoracic radiographs of two normal dogs from different b...

Figure 16.3 Lateral thoracic radiographs of two normal cats, one young adult...

Figure 16.4 Lateral thoracic radiograph of a normal dog showing the approxim...

Figure 16.5 Calculation of the vertebral heart score (VHS) from a thoracic l...

Figure 16.6 Clock face analogy (a) applied to the canine cardiac silhouette ...

Figure 16.7 Thoracic radiographs of three different dogs with compensated (a...

Figure 16.8 Thoracic radiographs of two dogs with patent ductus arteriosus (...

Figure 16.9 Thoracic radiographs of a cat with left‐sided congestive heart f...

Figure 16.10 Thoracic radiographs of a Doberman with acute left‐sided conges...

Figure 16.11 Thoracic radiographs of two dogs with marked right heart enlarg...

Figure 16.12 Lateral (a) and ventrodorsal (b) thoracic radiographs of a dog ...

Figure 16.13 Two‐dimensional right parasternal transventricular short‐axis v...

Figure 16.14 Two‐dimensional right parasternal transmitral short‐axis view. ...

Figure 16.15 Two‐dimensional right parasternal transaortic short‐axis view i...

Figure 16.16 Two‐dimensional right parasternal long‐axis four‐chamber view i...

Figure 16.17 Two‐dimensional right parasternal long‐axis five‐chamber view i...

Figure 16.18 Two‐dimensional left apical (or caudal) four‐ and five‐chamber ...

Figure 16.19 M‐mode echocardiograms obtained from two normal dogs at the ven...

Figure 16.20 Abnormal M‐mode echocardiograms obtained from three cats with h...

Figure 16.21 Doppler evaluation of systolic pulmonary flow in normal dogs us...

Figure 16.22 Doppler evaluation of systolic aortic flow in normal dogs using...

Figure 16.23 Doppler evaluation of diastolic mitral (a–c,e) and tricuspid (d...

Figure 16.24 Aliasing artifact associated with the pulsed‐wave Doppler mode....

Figure 16.25 Use of pulmonary regurgitation for the diagnosis of diastolic p...

Figure 16.26 Examples of abnormal pulmonary flow patterns assessed by pulsed...

Figure 16.27 Examples of abnormal aortic flow patterns associated with subao...

Figure 16.28 Evaluation of aortic insufficiency severity using color‐coded M...

Figure 16.29 Examples of abnormal diastolic transmitral inflows obtained fro...

Figure 16.30 Semi‐quantitative assessment of mitral insufficiency using the ...

Figure 16.31 Assessment of left‐to‐right congenital shunts in dogs using Dop...

Figure 16.32 Tissue Doppler imaging (TDI) and TDI‐derived techniques. Using ...

Figure 16.33 Longitudinal myocardial deformation (strain) assessed by speckl...

Chapter 17

Figure 17.1 The standardized positions of the electrodes on the body are def...

Figure 17.2 The augmented (unipolar) limb leads use the same electrodes as l...

Figure 17.3 Major deflections and intervals of the ECG (lead II). See text f...

Figure 17.4 Calibration of ECG paper speed and sensitivity. See text for det...

Figure 17.5 Calculation of instantaneous heart rate between two beats is use...

Figure 17.6 Calculation of average heart rate, used when rhythm is irregular...

Figure 17.7 The hexaxial or six‐lead ECG system divides the frontal plane in...

Figure 17.8 Calculation of the MEA is performed by first examining the polar...

Figure 17.9 Calculation of the mean electrical axis using the “pie method.” ...

Figure 17.10 Six‐lead ECG example of a right axis shift and right bundle bra...

Figure 17.11 Atrial enlargement is manifest as a P‐wave of increased amplitu...

Figure 17.12 ECG example of a left bundle branch block in a rottweiler with ...

Chapter 18

Figure 18.1 A family of Frank–Starling curves highlighting the progression t...

Chapter 20

Figure 20.1 ECG and Holter tracings from a boxer dog acquired during a scree...

Figure 20.2 Lead II ECG from a dog with single monomorphic ventricular prema...

Figure 20.3 Lead II ECG from a cat with a monomorphic ventricular tachycardi...

Figure 20.4 ECG strip from a dog in ventricular fibrillation. Ventricular fi...

Figure 20.5 Three‐lead ECG from a Doberman pinscher with polymorphic ventric...

Figure 20.6 Six‐lead ECG from a dog with an accelerated idioventricular rhyt...

Chapter 21

Figure 21.1 Supraventricular structures include the sinus node, the atrial m...

Figure 21.2 ECG of a healthy dog illustrating respiratory sinus arrhythmia w...

Figure 21.3 Six‐lead ECG of a dog with sick sinus syndrome. After the first ...

Figure 21.4 Permanent transvenous pacemaker in a dog with third‐degree atrio...

Figure 21.5 ECG strips of a dog with hyperkalemia. As serum potassium increa...

Figure 21.6 ECG strips of dogs with atrioventricular block. (a) First‐degree...

Figure 21.7 Six‐lead ECG of a dog with atrial fibrillation (speed: 50 mm/s)....

Figure 21.8 Ventricular preexcitation. (a) When a dog has an accessory pathw...

Chapter 23

Figure 23.1 Pulmonary hypertension classification (see text for details). CO...

Figure 23.2 Thoracic radiographs from a dog with severe pulmonary hypertensi...

Figure 23.3 Electrocardiogram from a dog with severe pulmonary hypertension ...

Figure 23.4 Tricuspid regurgitation in a dog with severe pulmonary hypertens...

Figure 23.5 Pulmonic insufficiency in a dog with severe pulmonary hypertensi...

Figure 23.6 Septal flattening in a dog with severe pulmonary hypertension se...

Chapter 24

Figure 24.1 Gross postmortem specimens of common congenital heart defects. (...

Figure 24.2 Example ECG traces from two dogs with congenital heart disease, ...

Figure 24.3 Compilation of thoracic radiographs from two dogs and a cat with...

Figure 24.4 Representative two‐dimensional echocardiographic images of commo...

Figure 24.5 Lateral nonselective digitally subtracted angiogram of a right‐t...

Figure 24.6 Selective right ventriculogram from a 6‐month‐old English bulldo...

Figure 24.7 Three‐dimensional reconstruction of a computed tomographic angio...

Figure 24.8 Fluoroscopic images obtained during transcatheter occlusion of P...

Chapter 25

Figure 25.1 Echocardiographic right parasternal long axis view of the left a...

Figure 25.2 Survival curves for dogs with different stages of heart failure ...

Figure 25.3 Echocardiographic long axis image of the aortic valve. A hyperch...

Chapter 26

Figure 26.1 Lead II ECG, 12.5 mm/s, 5 mm/mV. VPCs in a Doberman pinscher wit...

Figure 26.2 Lead II ECG, 25 mm/s, 5 mm/mV. Atrial fibrillation in a Golden r...

Figure 26.3 Lateral (a) and VD (b) thoracic radiographs in a Doberman with D...

Figure 26.4 Two‐dimensional echocardiographic images (right parasternal long...

Figure 26.5 Nine‐lead ECG, 25 mm/s, 5 mm/mV. Right ventricular VPCs (left bu...

Chapter 27

Figure 27.1 Myocardial disease phenotypes. There is overlap in the cardiac c...

Figure 27.2 Initial approach to the cat with tachypnea and suspected heart d...

Figure 27.3 Initial approach to the cat with suspected subclinical heart dis...

Chapter 28

Figure 28.1 Lateral and dorsoventral thoracic radiographs in three dogs with...

Figure 28.2 Transthoracic echocardiographic images of the left ventricle (LV...

Figure 28.3 Transthoracic echocardiographic images from dogs with cardiac tu...

Figure 28.4 Echocardiographic images obtained from a right parasternal long‐...

Figure 28.5 Electrocardiogram recordings from dogs with pericardial effusion...

Figure 28.6 Pericardiocentesis in a dog. This dog had a history of biting an...

Chapter 31

Figure 31.1 Thoracic radiographs with a diffuse bronchial pattern evidenced ...

Figure 31.2 Computed tomography slice of the thorax showing a “ground‐glass”...

Figure 31.3 Photomicroscopy from a patient diagnosed with chronic bronchitis...

Figure 31.4 Equipment set‐up for a modified technique to perform bronchoalve...

Chapter 32

Figure 32.1 A possible diagnostic algorithm for the investigation of small a...

Figure 32.2 A lateral thoracic radiograph from a dog with pulmonary thromboe...

Figure 32.3 Tissue factor‐activated thromboelastography tracings from a pati...

Figure 32.4 Long‐axis four‐chamber echocardiographic view showing a pendulou...

Figure 32.5 A transverse CT angiographic image of the heart and main pulmona...

Chapter 34

Figure 34.1 Normal pleura visualized via thoracoscopy.

Figure 34.2 (a,b) Thoracoscopic biopsy in a dog with mesothelioma.

Figure 34.3 Pyothorax cytology. Pyothorax in a dog with a predominance of ma...

Figure 34.4 Chylothorax cytology. Chylothorax in a cat consisting of a mixtu...

Chapter 39

Figure 39.1 Ventilation–perfusion mismatching. Partial pressure values are i...

Chapter 48

Figure 48.1 Left lateral (a) and ventrodorsal (b) radiographs of the thorax ...

Figure 48.2 Dorsally reconstructed CT enterography image (a) and correspondi...

Figure 48.3 Severe generalized dilation of the esophagus with fluid and gas ...

Figure 48.4 Moderate generalized dilation of the esophagus with gas in a dog...

Figure 48.5 Dorsoventral (a) and right lateral (b) radiographs of the thorax...

Figure 48.6 Esophageal perforation with secondary mediastinitis and pleuriti...

Figure 48.7 Esophageal foreign body. In the cranial cervical esophagus on a ...

Figure 48.8 Neoplasia of the caudal esophagus. In the caudal mediastinum, a ...

Figure 48.9 Sliding hiatal hernia (type 1 hiatal hernia) in a dog, which pre...

Figure 48.10 The movement of gastric content is dependent on the patient pos...

Figure 48.11 Normal gastrointestinal ultrasound images. Longitudinal ultraso...

Figure 48.12 Gastric dilation. Ventrodorsal (a), left lateral (b), and right...

Figure 48.13 Gastric dilation volvulus. Right lateral (a) and VD (b) radiogr...

Figure 48.14 Gastric pneumatosis in a Doberman with gastric dilation volvulu...

Figure 48.15 Ventrodorsal and left lateral radiographs of the abdomen of a v...

Figure 48.16 Longitudinal ultrasound image of the stomach of a dog with a hi...

Figure 48.17 Multiple gastric foreign bodies are noted in the ventrodorsal a...

Figure 48.18 Longitudinal ultrasound image of a thin, hyperechoic, linear fo...

Figure 48.19 Eosinophilic gastritis in a cat. Lateral radiograph (a) of the ...

Figure 48.20 Longitudinal ultrasound image of the stomach of a cat. A large,...

Figure 48.21 Longitudinal ultrasound image of the descending duodenum. The m...

Figure 48.22 Upper gastrointestinal contrast radiographic study of a cat. St...

Figure 48.23 Focal calcified peritoneal body (“Bates body”). Dorsoventral an...

Figure 48.24 Small intestinal mechanical ileus. Lateral and VD radiographs o...

Figure 48.25 Linear foreign body. Ventrodorsal and lateral radiographs of th...

Figure 48.26 Linear foreign body with perforation. Ventrodorsal (a) and late...

Figure 48.27 Jejunojejunal intussusception. Lateral (a) and ventrodorsal (b)...

Figure 48.28 Intestinal lymphoma. Lateral radiograph (a) of the abdomen of a...

Figure 48.29 Longitudinal ultrasound images demonstrating severely corrugate...

Figure 48.30 Virtual colonoscopy. Three‐dimensional reconstruction virtual c...

Figure 48.31 Cecal perforation secondary to typhlitis. Right lateral (a) and...

Figure 48.32 Lymphoma of the colon wall in a cat. Transverse (a) and longitu...

Figure 48.33 Megacolon in an obstipated cat. Right lateral (a) and ventrodor...

Figure 48.34 Lumbosacral malformation in a Manx cat with secondary megacolon...

Figure 48.35 Severe megacolon in a Manx cat. Ventrodorsal (a) and lateral (b...

Figure 48.36 Stone in colon. Ventrodorsal (a) and left lateral (b) radiograp...

Figure 48.37 Severe sublumbar lymphadenopathy secondary to prostate neoplasi...

Figure 48.38 Colonocolic intussusception. On survey radiographs (a), a soft ...

Figure 48.39 Cecocolic intussusception (cecal inversion) in a dog. Ventrodor...

Figure 48.40 Colon torsion. Left lateral (a), right lateral (b), and ventrod...

Chapter 49

Figure 49.1 A typical flexible videoendoscopy “tower” as used for most gastr...

Figure 49.2 Control cluster of a typical flexible videoendoscope, in this ca...

Figure 49.3 Maximal upwards flexion of a flexible videoendoscope, necessary ...

Figure 49.4 Attachment of a specialized manifold in place of the air/water a...

Figure 49.5 Clean and dry flexible endoscopes stored in a dedicated storage ...

Figure 49.6 Increased friability and iatrogenic mucosal compromise of the sm...

Figure 49.7 Increased mucosal granularity in the small intestine. The endosc...

Figure 49.8 Erosions in the gastric mucosa. In the lower left of image (a), ...

Figure 49.9 Diffuse lymphatic drainage abnormality in a dog with marked prot...

Figure 49.10 Luminal mass effect, a benign rectal polyp in a dog. The mucosa...

Figure 49.11 Esophagitis, likely due to recurrent gastroesophageal reflux, i...

Figure 49.12 Severe ulceration on the wall of the gastric lesser curvature i...

Figure 49.13 View of a normal descending duodenum from just distal to the py...

Figure 49.14 Normal villi in the distal descending duodenum. This is the sam...

Figure 49.15 Severe lymphangiectasia in the very cranial aspect of the jejun...

Figure 49.16 Colonic view of the normal ileocolic junction in a dog. The ile...

Figure 49.17 A large, severely ulcerated mass lesion in the descending colon...

Figure 49.18 A hemispherical jaw biopsy instrument exits the distal end of a...

Figure 49.19 A selection of manipulating and retrieval instruments, which ma...

Figure 49.20 Composite image showing relative size and internal structure of...

Figure 49.21 Composite image showing several captures from a capsule endosco...

Chapter 50

Figure 50.1 (a) Photograph of a 15‐year‐old Pomeranian, showing severe calcu...

Figure 50.2 (a) Photograph of a 2‐year‐old Abyssinian, showing severe gingiv...

Figure 50.3 Photograph of a pyogenic granuloma in a 5‐year‐old domestic shor...

Figure 50.4 Photographs of multiple patients showing varying presentations o...

Figure 50.5 Photograph (a) and transverse computed tomographic image in soft...

Figure 50.6 Photographs of eosinophilic granuloma involving the dorsal tongu...

Figure 50.7 Photographs of a 6‐month‐old mixed breed with erythema multiform...

Figure 50.8 Photographs of a 1‐month‐old domestic shorthair with electric bu...

Chapter 53

Figure 53.1 (a) Physiologic swallow pressure topography of a healthy dog ext...

Chapter 54

Figure 54.1 This dog presented with significant weight loss due to EPI. The ...

Figure 54.2 The feces from the dog in Picture 1. The feces are large in volu...

Chapter 55

Figure 55.1 (a) Ultrasound image of pancreas with large fluid‐filled lesion ...

Figure 55.2 Abdominal radiographs of a dog with free fluid (lateral (a) and ...

Figure 55.3 VD radiograph of a dog with acute pancreatitis. The descending d...

Figure 55.4 (a) Ultrasound image of enlarged hypoechoic right pancreatic lim...

Figure 55.5 A diagnostic algorithm for the diagnosis of acute pancreatitis i...

Chapter 57

Figure 57.1 Type II atresia ani in an 8‐week‐old mixed‐breed puppy. Note the...

Figure 57.2 Intraoperative view of a severely distended and atonic colon in ...

Figure 57.3 Composite images of the perineum of an 8‐year‐old spayed female ...

Figure 57.4 Endoscopic view of a benign rectal polyp in a dog. A large, semi...

Figure 57.5 Rectal prolapse in a puppy with a history of diarrhea. Note the ...

Figure 57.6 Early intraoperative view of a rectal pull‐through procedure to ...

Chapter 58

Figure 58.1 Dysbiosis in dogs with IBD. (

Left

) Several major bacterial group...

Chapter 59

Figure 59.1 Current hypothesis of pathogenesis of CE in dogs. Genetic mutati...

Chapter 60

Figure 60.1 Canine eye showing jaundiced sclera.

Figure 60.2 Dalmatian showing head pressing as a manifestation of hepatic en...

Chapter 61

Figure 61.1 (a) Right lateral recumbent radiograph of a normal cat’s abdomen...

Figure 61.2 (a) Right lateral radiograph showing the abdomen of a dog with h...

Figure 61.3 Right lateral recumbent radiography of a dog with large mass cau...

Figure 61.4 Right lateral recumbent radiograph of a female chondrodystrophic...

Figure 61.5 A sagittal plane ultrasound image of a normal canine liver. The ...

Figure 61.6 Sagittal plane ultrasound images showing the liver of a patient ...

Figure 61.7 Sagittal plane ultrasound image showing the liver of a patient w...

Figure 61.8 Sagittal plane ultrasound image showing the liver of a Cavalier ...

Figure 61.9 Sagittal plane ultrasound image demonstrating a well‐defined het...

Figure 61.10 Sagittal plane ultrasound image showing a multiloculated cystic...

Figure 61.11 Sagittal plane ultrasound images showing target lesions (

blue a

...

Figure 61.12 Ultrasound image of a 14‐year‐old MN Siamese showing moderate d...

Figure 61.13 Sagittal plane ultrasound image showing the liver of a jaundice...

Figure 61.14 Ultrasound image showing the typical “kiwi‐like” appearance of ...

Figure 61.15 Ultrasound image showing thickening of the gallbladder wall (

bl

...

Figure 61.16 Color Doppler ultrasound image showing an extrahepatic portocav...

Figure 61.17 Color Doppler ultrasound image showing a left divisional intrah...

Figure 61.18 Ventrodorsal intraoperative fluoroscopic image acquired immedia...

Figure 61.19 Color Doppler ultrasound image highlighting a portal thrombus a...

Chapter 63

Figure 63.1 Diagrammatic representation of normal biliary physiology. Choles...

Figure 63.2 Ultrasound images from a cat diagnosed with neutrophilic cholang...

Chapter 64

Figure 64.1 Low‐power photomicrograph of liver tissue from an English spring...

Chapter 65

Figure 65.1 Laparoscopic view of a cirrhotic liver secondary to toxin insult...

Figure 65.2 Ultrasonographic image of a cirrhotic liver. Note the presence o...

Chapter 67

Figure 67.1 A distended gallbladder removed from a dog with a mucocele.

Chapter 69

Figure 69.1 A lateral radiograph of the lumbar vertebrae illustrating the th...

Figure 69.2 A lateral radiograph of the thoracic vertebrae confirms a fractu...

Figure 69.3 A sagittal reconstructed CT scan of the thoracic vertebrae of th...

Figure 69.4 A 3D CT reconstruction of the thoracic vertebrae of the case see...

Figure 69.5 A sagittal (a) and transverse (b) T2‐weighted MRI of the case se...

Figure 69.6 Securing a dog or cat to a board in lateral recumbency can reduc...

Figure 69.7 Multiple internal fixation materials and methods exist to stabil...

Figure 69.8 Fixation failure can be due to breakage or migration of the impl...

Figure 69.9 A sagittal T2‐weighted MRI confirms cerebellar vermal herniation...

Figure 69.10 Extensor rigidity of the limbs as seen in this cat can be compa...

Figure 69.11 A lateral skull radiograph shows a frontal bone fracture (

arrow

Figure 69.12 A transverse bone windowed CT scan of the dog in Fig. 69.11 con...

Figure 69.13 A transverse T2‐weighted MRI of the dog in Fig. 69.11 confirms ...

Chapter 70

Figure 70.1 Pathophysiology of epileptic seizure generation. Reverberating c...

Figure 70.2 Diagnostic paradigm for hyperkinetic movement disorders.

Chapter 71

Figure 71.1 Histopathology of the cerebellum of a dog with L2‐hydroxyglutari...

Figure 71.2 Dorsal plane CT scan of the brain of a dog with obstructive hydr...

Chapter 77

Figure 77.1 Idiopathic optic neuritis in a dog. Note the optic disc is edema...

Figure 77.2 Internal ophthalmoplegia in a dog. The right pupil is normal. Th...

Figure 77.3 Neurotrophic and neuroparalytic keratitis in a dog. Note the lef...

Figure 77.4 Horner's syndrome in a cat, demonstrating ptosis of the left upp...

Chapter 78

Figure 78.1 Epidemic curves.

Chapter 79

Figure 79.1 Lymph node aspirate from a dog. Note the increased numbers of pl...

Figure 79.2 Blood smears from two different dogs. (

Right

) A large form of

Ba

...

Figure 79.3 Kidney aspirate from a cat. Note neutrophilic‐macrophagic inflam...

Figure 79.4 Thoracic mass from a German Shepherd dog. Note the necrotic back...

Figure 79.5 Inguinal subcutaneous mass in a dog. Note the marked neutrophili...

Chapter 82

Figure 82.1 Supportive care for CPV.

Chapter 93

Figure 93.1 Phylogeny of selected organisms of veterinary importance from An...

Figure 93.2 Ehrlichial morulae (

black arrows

) in canine leukocytes as seen i...

Figure 93.3 Distribution of

Amblyomma americanum

,

Dermacentor variabilis

,

Ix

...

Figure 93.4 Seroprevalence by state of

E. chaffeensis

(

green

) and

E. ewingii

Figure 93.5 Corneal edema, opacity, and pigmentation in a dog with uveitis c...

Chapter 94

Figure 94.1 Fine‐needle aspirate of mesenteric lymph node of a dog with salm...

Chapter 95

Figure 95.1 Ultrastructural location of Wolbachia within their filarial host...

Chapter 96

Figure 96.1 Endocarditis caused by

Bartonella vinsonii

subsp.

berkhoffii

in ...

Figure 96.2 Computed tomography (CT) of spinal cord compression (a,

black ar

...

Figure 96.3 Bacillary angiomatosis in a dog. (a) Erythematous nodular skin l...

Figure 96.4 Radiograph images of the right forelimb of a cat with osteomyeli...

Chapter 97

Figure 97.1 Hemoplasma organism numbers in the blood of four cats infected w...

Chapter 98

Figure 98.1 Cultivation.

Chapter 103

Figure 103.1 Reported tularemia cases in the United States, 2016.

Chapter 108

Figure 108.1 Inguinal panniculitis in a cat.

Figure 108.2 Acid‐fast bacilli in a sample from a cat with feline leprosy.

Chapter 109

Figure 109.1 Fox terrier with dermatophytosis caused by

Trichophyton mentagr

...

Figure 109.2 Cytology of a fine needle aspirate of a skin lesion from a dog ...

Figure 109.3 Cytology showing multiple intracellular

Histoplasma capsulatum

...

Figure 109.4 Histopathology showing large numbers of

Cryptococcus

organisms ...

Figure 109.5 Cytology of a tracheal wash specimen showing a

Coccidioides

sph...

Figure 109.6 Nasal depigmentation and ulceration in a dog with sinonasal asp...

Figure 109.7 Cytology of an impression smear of a skin lesion from a cat wit...

Figure 109.8 Histopathology of a polyp caused by

Rhinosporidium seeberi

. Spo...

Chapter 110

Figure 110.1 A positive indirect fluorescent antigen test serologic response...

Figure 110.2 A young puppy with hindlimb paresis due to

Neospora caninum

inf...

Figure 110.3 Trypomastigotes of

Trypanosoma congolense

in a blood smear from...

Figure 110.4

Hepatozoon canis

gamont in a neutrophil from the blood smear of...

Figure 110.5

Tritrichomonas foetus

in a stained fecal smear from a naturally...

Chapter 111

Figure 111.1 (a) Sporulated and (b) unsporulated

Cystoisospora ohioensis

....

Chapter 118

Figure 118.1 Partition of total body water (TBW) into body compartments. See...

Chapter 119

Figure 119.1 Phosphorus homeostasis in the body.

Figure 119.2 Hormonal regulation of phosphorus in health. 1,25 (OH)

2

Vit D, ...

Chapter 122

Figure 122.1 Potential ECG changes associated with (a) moderate (approx. 6.0...

Figure 122.2 Lateral abdominal radiographic projection of a cat depicting (a...

Figure 122.3 Lateral abdominal radiographic projection of a dog depicting pr...

Figure 122.4 Lateral abdominal radiographic projection of a cat depicting th...

Figure 122.5 Once the catheter is seeded in the distal urethral, the prepuce...

Figure 122.6 Radiographic images of antegrade urethral catheterization for u...

Figure 122.7 Fluoroscopic images during urethral stent placement from a 9‐ye...

Figure 122.8 Radiographic images from a male mixed‐breed dog with a urethral...

Figure 122.9 Ultrasound images of ureteral obstruction in a dog (a) and cat ...

Figure 122.10 Radiographic images from a cat with complete right ureteral ob...

Figure 122.11 Radiographic images from a cat with a subcutaneous ureteral by...

Figure 122.12 Fluoroscopic images from an 8‐year‐old Labrador retriever with...

Chapter 123

Figure 123.1 One canine oxalate urolith from a 12‐year‐old female spayed min...

Figure 123.2 Feline oxalate stones from a 16‐year‐old female spayed domestic...

Figure 123.3 Bladder struvite uroliths retrieved from a 10‐year‐old female s...

Figure 123.4 Normal canine purine degradation pathway.

Figure 123.5 Urate stones retrieved from a 12‐year‐old male neutered Dalmati...

Figure 123.6 Xanthine stone retrieved from a 2‐year‐old male neutered Dalmat...

Figure 123.7 Suture‐induced stone removed from the bladder of a 7‐year‐old m...

Figure 123.8 Suture‐induced stone (60% struvite, 40% calcium phosphate) remo...

Figure 123.9 Melamine cyanuric acid removed from the bladder of a Burmese ca...

Figure 123.10 Stone layers description.

Figure 123.11 Abdominal radiographs (lateral view) showing bladder stones in...

Figure 123.12 Abdominal radiographs (lateral view) showing bladder and ureth...

Figure 123.13 Double‐contrast cystography (lateral view) in a dog showing mu...

Figure 123.14 (a) Cystine stone in a 3‐year‐old male pug. (b) Struvite uroli...

Figure 123.15 (a) Vertical positioning of a female dog to perform voiding ur...

Figure 123.16 Visualization of bladder stones (oxalate) before (a) and after...

Figure 123.17 Percutaneous cystolithotomy performed in a male dog. (a) A sin...

Figure 123.18 Preoperative lateral (a), postoperative lateral (b) and ventro...

Figure 123.19 Lateral radiographs of a feline patient following the placemen...

Chapter 124

Figure 124.1 Ultrasound transverse view image of a normal prostate of an int...

Figure 124.2 Ultrasound transverse view image of an atrophied prostate in a ...

Figure 124.3 Benign prostatic hypertrophy as seen on ultrasound in both tran...

Figure 124.4 Benign prostatic hypertrophy with prostatic cysts as seen on ul...

Figure 124.5 Paraprostatic cyst as seen on sagittal ultrasound view. BL, uri...

Figure 124.6 Prostatic abscess and prostatitis as seen on ultrasound transve...

Chapter 125

Figure 125.1 Flowchart for adjusting ACEI therapy. ACEI, angiotensin‐convert...

Chapter 126

Figure 126.1 This cat had hyperkalemic acute kidney injury secondary to bila...

Figure 126.2 This dog was diagnosed with leptospirosis and was initially tre...

Chapter 127

Figure 127.1 An overview of the neural control of micturition consisting of ...

Figure 127.2 Diagnostic approach to the patient with urinary incontinence. T...

Chapter 133

Figure 133.1 Photomicrograph of lymphocytes in the peripheral blood of a dog...

Figure 133.2 Photomicrograph of lymphoblasts in the peripheral blood of a do...

Figure 133.3 Photomicrograph of poorly differentiated blast cells in the per...

Chapter 135

Figure 135.1 Oral extramedullary plasmacytoma in the maxilla of a dog.

Figure 135.2 Serum protein electrophoresis results in a dog with MM. The alb...

Figure 135.3 Lateral radiograph showing well‐demarcated small “punched out” ...

Figure 135.4 Bone marrow aspirate from a dog with multiple myeloma showing a...

Chapter 136

Figure 136.1 T1‐weighted post‐contrast (gadolinium) coronal image of a front...

Figure 136.2 T1‐weighted postcontrast (gadolinium) sagittal image of a cervi...

Chapter 138

Figure 138.1 (a) Squamous cell carcinoma involving the third eyelid of a cat...

Figure 138.2 (a) Free‐floating uveal cysts in the anterior chamber of a dog....

Figure 138.3 (a) Feline diffuse iris melanoma. The right iris is diffusely a...

Figure 138.4 Canine iridociliary epithelial tumor. There is a nonpigmented, ...

Figure 138.5 (a) Orbital mass in a dog with exophthalmos and dorsal deviatio...

Chapter 147

Figure 147.1 Fine needle aspirate of a canine TVT. Note the homogeneous popu...

Chapter 150

Figure 150.1 Orthogonal view radiographs (cranial‐caudal (a), lateral (b)) o...

Chapter 153

Figure 153.1 Xenogeneic DNA immunization concept.

Chapter 155

Figure 155.1 A MCT at the mucocutaneous junction of the nasal planum. Tumors...

Figure 155.2 Mast cells seen at 40× with varying amounts of metachromatic gr...

Figure 155.3 A population of Diff‐Quik stained round cells at 40×. Notice th...

Figure 155.4 (a) A female mixed‐breed dog at initial presentation with a MCT...

Figure 155.5 (a) A female boxer at presentation with over 300 dermal MCTs. (...

Figure 155.6 A clinically aggressive feline MCT. Note the change in colorati...

Chapter 157

Figure 157.1

Macule

– pigment changes occur due to increased or decreased me...

Figure 157.2

Papule

– these palpably solid elevations are usually pink to re...

Figure 157.3

Vesicle

– lesions are fragile, transient, and difficult to find...

Figure 157.4

Pustule

– lesions arise due to neutrophilic inflammation, occas...

Figure 157.5

Wheal (hive)

– these edematous lesions typically disappear with...

Figure 157.6

Nodule

– these lesions develop due to an inflammatory or neopla...

Figure 157.7

Epidermal collarette

– these are formed from the remnants of a ...

Figure 157.8

Excoriation

– these lesions are self‐induced and occur secondar...

Figure 157.9

Erosion/ulceration

– develop due to rapid death and/or loss of ...

Figure 157.10

Fissure

– lesions may be caused by underlying disease or injur...

Figure 157.11

Lichenification

– results from chronic trauma, often due to fr...

Figure 157.12

Alopecia

– may arise from several causes that lead to damage t...

Figure 157.13

Scale

– results from increased production of keratinocytes, su...

Figure 157.14

Crust

– forms when purulent exudate, serum, blood, other dried...

Figure 157.15

Follicular casts

– these lesions are composed of a combination...

Figure 157.16

Comedones

– in general, these lesions may form as a result of ...

Figure 157.17

Pigmentary abnormalities

– hypopigmentation‐hypomelanosis occu...

Figure 157.18

Pigmentary abnormalities

– hyperpigmentation‐hypermelanosis oc...

Chapter 159

Figure 159.1 Moderately erythematous, coalescing macules in the inguinal reg...

Figure 159.2 Pinpoint, faint papules on the sternum of a dog with mild atopi...

Figure 159.3 Marked lichenification and hyperpigmentation of the periocular ...

Figure 159.4 Salivary staining on the paws of a patient with atopic dermatit...

Figure 159.5 Cat with moderate‐to‐severe periocular erythema, swelling, and ...

Figure 159.6 Self‐induced noninflammatory alopecia on the abdomen of an atop...

Figure 159.7 Miliary dermatitis lesions (crusted erythematous papules) on th...

Figure 159.8 Eosinophilic plaque lesions on the ventral abdomen of an allerg...

Figure 159.9 Unilateral indolent ulcer on the upper lip of an allergic cat....

Figure 159.10 Intradermal allergen test showing several positive reactions t...

Chapter 160

Figure 160.1 Five‐year‐old male neutered mixed‐breed dog with multifocal whe...

Figure 160.2 Three‐year‐old female spayed mastiff with facial angioedema.

Figure 160.3 Severe contact dermatitis to a plant fertilizer in a 5‐year‐old...

Figure 160.4 Five‐year‐old female spayed mixed‐breed dog with flea allergy d...

Figure 160.5 An indolent ulcer in a 4‐year‐old female spayed domestic shorth...

Chapter 161

Figure 161.1 Periocular lichenification, crusting, and hyperpigmentation in ...

Figure 161.2 Erythematous otitis externa in an 8‐year‐old, female spayed gol...

Figure 161.3 Ventral lichenification, ulceration, and crusting in a 7‐year‐o...

Chapter 162

Figure 162.1 Less than 1‐year‐old, male, intact collie with nonpruritic alop...

Figure 162.2 Middle‐aged, male, neutered Siberian husky with crusting, depig...

Figure 162.3 One‐year‐old German shorthaired pointer with exfoliative cutane...

Figure 162.4 Three‐year‐old collie with vesicular cutaneous lupus. Note the ...

Figure 162.5 One‐year‐old Great Dane with epidermolysis bullosa acquisita. N...

Figure 162.6 Sample collected from a pustule in a case of pemphigus foliaceu...

Figure 162.7 Cocker spaniel with pemphigus foliaceus. Multifocal to coalesci...

Figure 162.8 Domestic shorthair cat with caseous debris and erythema of the ...

Chapter 163

Figure 163.1 A 3‐year‐old male castrated English bulldog with patchy alopeci...

Figure 163.2 Adult male castrated toy poodle with focal alopecia secondary t...

Figure 163.3 Neck region of a 9‐year‐old female spayed gray and white Italia...

Figure 163.4 Adult male castrated Pomeranian dog with alopecia X. Note that ...

Figure 163.5 Patterned alopecia in a young adult female spayed Boston terrie...