Duncan and Prasse's Veterinary Laboratory Medicine E-Book

• Herausgeber: John Wiley & Sons
• Kategorie: Fachliteratur
• Sprache: Englisch

Seitenzahl: 945

Veröffentlichungsjahr: 2011

Beschreibung

Now in full color throughout, Duncan and Prasse's Veterinary Laboratory Medicine: Clinical Pathology, Fifth Edition offers a comprehensive overview of hematology, hemostasis, clinical chemistry, urinalysis, cytology, and reference intervals in a highly accessible outline format. With information on all major domestic species, the text is designed for the reader to quickly find answers to clinical questions. Taking a problem-solving approach to the interpretation of laboratory data, this book includes clinical cases to illustrate the concepts of laboratory data interpretation, with tables and key words to aid readers in locating and applying information. The fifth edition has been fully revised to reflect the latest knowledge, diagnostic methods, and practices in veterinary laboratory medicine. A companion website provides the images in PowerPoint and references linked to PubMed at href="http://www.wiley.com/go/latimer">www.wiley.com/go/latimer. Duncan and Prasse's Veterinary Laboratory Medicine is an excellent quick reference for practicing veterinarians, veterinary students, clinical interns and residents, and pathology residents.

Leseprobe

Contents

CONTRIBUTING AUTHORS

PREFACE

ACKNOWLEDGMENTS

CHAPTER 1 ERYTHROCYTES

BASIC CONCEPTS OF ERYTHROCYTE FUNCTION, METABOLISM, PRODUCTION, AND BREAKDOWN

MEANS OF EVALUATING ERYTHROCYTES

ANEMIA: DIAGNOSIS AND CLASSIFICATION

ANEMIA FROM BLOOD LOSS (HEMORRHAGIC ANEMIA) (TABLE 1.1)

ANEMIA FROM ACCELERATED ERYTHROCYTE DESTRUCTION (HEMOLYTIC ANEMIA) (TABLE 1.2)

ANEMIA FROM REDUCED OR DEFECTIVE ERYTHROPOIESIS (TABLE 1.3)

POLYCYTHEMIA

REFERENCES

CHAPTER 2 LEUKOCYTES

ESSENTIAL CONCEPTS OF LEUKOCYTE MORPHOLOGY, FUNCTION, PRODUCTION, AND KINETICS

LABORATORY EVALUATION OF LEUKOCYTES

INTERPRETATION OF LEUKOCYTE RESPONSES

REFERENCES

CHAPTER 3 HEMATOPOIETIC NEOPLASIA

LYMPHOPROLIFERATIVE DISORDERS

MYELOPROLIFERATIVE DISORDERS

REFERENCES

CHAPTER 4 HEMOSTASIS

ESSENTIAL CONCEPTS

ENDOTHELIUM

PLATELETS

COAGULATION AND FIBRINOLYSIS

REFERENCES

CHAPTER 5 WATER, ELECTROLYTES, AND ACID BASE

TOTAL BODY WATER AND OSMOLALITY

DETERMINATION OF BLOOD GASES AND ELECTROLYTES

ACID-BASE INTERPRETATION BASED ON STRONG ION DIFFERENCE: STEWART’s SID THEORY

VARIATIONS OF BLOOD pH AND ELECTROLYTE CONCENTRATIONS

DISORDERS OF ELECTROLYTES AND METABOLIC ACID BASE IMBALANCE

DISORDERS OF RESPIRATORY FUNCTION

REFERENCES

CHAPTER 6 PROTEINS, LIPIDS, AND CARBOHYDRATES

PLASMA PROTEINS

PLASMA LIPIDS

PLASMA CARBOHYDRATES

REFERENCES

CHAPTER 7 LIVER

HEPATIC ABNORMALITIES DETECTED BY LABORATORY TESTS

HEPATIC LABORATORY TESTS

BIOCHEMICAL PROFILES OF HEPATIC DISEASES

REFERENCES

CHAPTER 8 DIGESTIVE SYSTEM

EXOCRINE PANCREAS

LABORATORY DETECTION OF PANCREATITIS

LABORATORY DETECTION OF MALASSIMILATION ATTRIBUTABLE TO MALDIGESTION (EXOCRINE PANCREATIC INSUFFICIENCY)

LABORATORY DETECTION OF MALASSIMILATION ATTRIBUTABLE TO MALABSORPTION

LABORATORY DETECTION OF OTHER DIGESTIVE DISORDERS

REFERENCES

CHAPTER 9 URINARY SYSTEM

URINALYSIS

RENAL ABNORMALITIES DETECTED BY LABORATORY TESTS

REFERENCES

CHAPTER 10 MUSCLE

REFERENCES

CHAPTER 11 ENDOCRINE SYSTEM

PARATHYROID GLAND, CALCIUM, PHOSPHORUS, AND MAGNESIUM

THYROID FUNCTION

ENDOCRINE PANCREAS

ADRENAL CORTEX

REFERENCES

CHAPTER 12 CYTOLOGY

INTRODUCTION

REFERENCES

CHAPTER 13 GENERATING AND INTERPRETING

REFERENCES

CASE STUDIES

INDEX

This edition first published 2011 © 2011 by John Wiley & Sons, Inc.

Previous editions © 1977, 1986, 1994, 2003 Iowa State University Press

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Library of Congress Cataloging-in-Publication Data

Duncan & Prasse’s veterinary laboratory medicine: clinical pathology / [edited by] Kenneth S. Latimer. – 5th ed.

p.; cm.

Duncan and Prasse’s veterinary laboratory medicine

Veterinary laboratory medicine

Rev. ed. of: Duncan & Prasse’s veterinary laboratory medicine/Kenneth S. Latimer, Edward a. Mahaffey, Keith W. Prasse. 4th ed. 2003.

Includes bibliographical references and index.

ISBN 978-0-8138-2014-9 (hardcover: alk. paper) 1. Veterinary clinical pathology. I. Latimer, Kenneth S. II. Duncan, J. Robert. III. Latimer, Kenneth S. Duncan & Prasse’s veterinary laboratory medicine. IV. Title: Duncan and Prasse’s veterinary laboratory medicine. V. Title: Veterinary laboratory medicine.

[DNLM: 1. Pathology, Veterinary–Outlines. 2. Pathology, Clinical–Outlines. SF 772.6]

SF772.6.D86 2011

636.089'607–dc22

2010049553

A catalogue record for this book is available from the British Library.

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CONTRIBUTING AUTHORS

Perry J. Bain, DVM, PhD

Diplomate, American College of Veterinary

Pathologists

Assistant Professor

Department of Biomedical Sciences

Large Animal Hospital

Cummings School of Veterinary Medicine at

Tufts University

North Grafton, MA 01536

Holly S. Bender, DVM, PhD

Diplomate, American College of Veterinary

Pathologists

Professor

Department of Veterinary Pathology

College of Veterinary Medicine

Iowa State University

Ames, IA 50011

Dorothee Bienzle, DVM, MSc, PhD

Diplomate, American College of Veterinary

Pathologists

Professor and Canada Research Chair in

Veterinary Pathology

Department of Pathobiology

Ontario Veterinary College

University of Guelph

Guelph, Ontario, Canada N1G 2W1

Mary K. Boudreaux, DVM, PhD

Professor

Department of Pathobiology

College of Veterinary Medicine

Auburn University, AL 36849

Denise I. Bounous, DVM, PhD

Medical Technologist (American Society of Clinical Pathologists)

Diplomate, American College of Veterinary

Pathologists

Group Director, Drug Safety Evaluation

Bristol-Myers Squibb

Princeton, NJ 08543

Charles W. Brockus, DVM, PhD

Diplomate, American College of Veterinary

Internal Medicine

Diplomate, American College of Veterinary

Pathologists

Charles River

Reno, NV 89511

Ellen W. Evans, DVM, PhD

Diplomate, American College of Veterinary

Pathologists

Senior Director, Immunotoxicology Center of Emphasis

Pfizer, Inc.

Groton, CT 06340

Duncan C. Ferguson, VMD, PhD

Diplomate, American College of Veterinary

Internal Medicine

Diplomate, American College of Veterinary

Clinical Pharmacology

Professor and Head

Department of Veterinary Biosciences

College of Veterinary Medicine

University of Illinois at Urbana-Champaign

Urbana, IL 61802

Jeanne W. George, DVM, PhD

Diplomate, American College of Veterinary

Pathologists

Professor Emeritus

Department of Pathology, Microbiology and Immunology

School of Veterinary Medicine

University of California-Davis

Davis, CA 95616

Christopher R. Gregory, DVM, PhD

Medical Technologist (American Society of Clinical Pathologists)

Associate Research Scientist

Department of Small Animal Medicine

College of Veterinary Medicine

The University of Georgia

Athens, GA 30602

Robert L. Hall, DVM, PhD

Diplomate, American College of Veterinary

Pathologists

Covance Laboratories, Inc.

Madison, WI 53704

Margarethe Hoenig, Dr med vet, PhD

Professor

Department of Veterinary Clinical Medicine

College of Veterinary Medicine

University of Illinois at Urbana-Champaign

Urbana, IL 61802

Paula M. Krimer, DVM, DVSc

Diplomate, American College of Veterinary

Pathologists

Assistant Professor

Athens Veterinary Diagnostic Laboratory

College of Veterinary Medicine

The University of Georgia

Athens, GA 30602

Kenneth S. Latimer, DVM, PhD

Diplomate, American College of Veterinary

Pathologists

Covance Laboratories, Inc.

Vienna, VA 22182

and

Professor Emeritus

Department of Pathology

College of Veterinary Medicine

The University of Georgia

Athens, GA 30602

Pauline M. Rakich, DVM, PhD

Diplomate, American College of Veterinary

Pathologists

Professor

Athens Veterinary Diagnostic Laboratory

College of Veterinary Medicine

The University of Georgia

Athens, GA 30602

Elizabeth A. Spangler, DVM, PhD

Diplomate, American College of Veterinary

Pathologists

Diplomate, American College of Veterinary

Internal Medicine

Assistant Professor

Department of Pathobiology

College of Veterinary Medicine

Auburn University, AL 36849

Heather L. Tarpley, DVM

Diplomate, American College of Veterinary

Pathologists

Chestatee Animal Hospital

Dahlonega, GA 30533

Niraj K. Tripathi, BVScAH, MVSc, PhD

Diplomate, American College of Veterinary

Pathologists

Covance Laboratories, Inc.

Madison, WI 53704

Julie L. Webb, DVM

Diplomate, American College of Veterinary

Pathologists

Instructor

Department of Pathobiological Sciences

College of Veterinary Medicine

University of Wisconsin

Madison, WI 53706

Elizabeth G. Welles, DVM, PhD

Diplomate, American College of Veterinary

Pathologists

Professor

Department of Pathobiology

College of Veterinary Medicine

Auburn University

Auburn, AL 36849

Shanon M. Zabolotzky, DVM

Diplomate, American College of Veterinary

Pathologists

Clinical Pathologist

IDEXX Laboratories, Inc.

West Sacramento, CA 95605

PREFACE

The publication of the fifth edition of Duncan & Prasse’s Veterinary Laboratory Medicine: ClinicalPathology represents a collation and distillation of educational information about veterinary clinical pathology that spans almost 40 years. Prior to retirement, Drs. Duncan and Prasse (Figure 1) established a legacy of excellence in teaching, diagnostic service, and applied research in veterinary clinical pathology that endures to the present day.

This textbook has evolved along with the specialty of veterinary clinical pathology. Since the initial American College of Veterinary Pathologists (ACVP) certification of Drs. Duncan and Prasse in clinical pathology, some of the new authors of this text now represent the third generation of veterinary clinical pathologists. General authorship also has continued to expand and the expertise of all coauthors has added a new dimension and considerable depth to the fifth edition of this textbook. Hopefully, a new editor will continue this legacy in the future to educate another generation of veterinary students, interns, residents, clinicians, and practitioners in the science, art, and practice of interpreting laboratory data.

Dr. J. Robert Duncan, Professor Emeritus (left), and Dr. Keith W. Prasse, Retired Dean (right), The University of Georgia College of Veterinary Medicine.

ACKNOWLEDGMENTS

This fifth edition of edition of Duncan & Prasse’s Veterinary Laboratory Medicine: Clinical Pathology would not have been possible without the assistance of several new and many repeat authors. Their professional contributions to this textbook are gratefully acknowledged and will have a positive impact on patient diagnostics and care. I would also like to recognize colleagues, clinical and anatomic pathology residents, veterinary students, and practicing veterinarians who have continued to provide the professional feedback that has improved the revision of this textbook. Kip Carter, MS, CMI, at The University of Georgia College of Veterinary Medicine again revised several line drawings. Erica Judisch, Nancy Turner, and the production staff at Wiley-Blackwell provided the professional assistance that was essential for the timely printing of this new edition. With the completion of this project, I can once again enjoy life with the whippets at home, in the show ring, and on the lure coursing field.

Cody (FC Longlesson Private Conversation) on the field and looking for action. Image courtesy of Julie Poole Photography, Knoxville, TN.