Evidence-Based Dermatology E-Book

• Herausgeber: John Wiley & Sons
• Kategorie: Fachliteratur
• Serie: Evidence-Based Medicine
• Sprache: Englisch

Seitenzahl: 2880

Veröffentlichungsjahr: 2014

Beschreibung

Be sure your skin-care treatments have strong evidential support

Evidence-based Dermatology, Third Edition takes a unique approach to clinical dermatology by emphasising use of only the highest quality available evidence when treating people with skin diseases.

Beginning with a toolbox introduction to the practice of evidence-based dermatology, it then covers the application of evidence for dermatological treatments across a wide range of ailments, including:

• Common inflammatory skin diseases
• Skin cancer, moles and actinic keratoses
• Infective skin disease, exanthems and infestations
• Disorders of pigmentation

In addition, many of the rarer skin disorders are also included so as to provide comprehensive coverage of the topic.

World-leading experts in dermatology follow a clinical approach for each disease, and as well as providing their expert guidance on the description and diagnosis of dermatologic disorders, they also discuss common dilemmas that clinicians face when considering the best approach to patient management. 'Key Points' accompany each chapter to provide a quick review of the most important points.

Clinically oriented and practically focused, Evidence-based Dermatology ensures that your treatments are entirely patient-focused and fully supported by the very latest medical evidence.

Leseprobe

Table of Contents

Dedication

Title page

Copyright page

Contributors

Foreword

References

Preface

About the Companion Website

PART I: The Concept of Evidence-Based Dermatology

CHAPTER 1: The Field and Its Boundaries

Introduction

What Is Special About Dermatology?

Limitations of Clinical Research

Evidence-Based medicine: Where Do We Go from Here?

References

Other Useful Resources

CHAPTER 2: The Rationale for Evidence-Based Dermatology

What Is Evidence-Based Dermatology?

The Process of Evidence-Based Dermatology

Conclusions

References

CHAPTER 3: The Role of Patient and Public Involvement in Evidence-Based Dermatology

Introduction

The Many Benefits and Roles of Patient and Public Involvement in Health Care

The Skin Shows: It Matters Psychologically and Socially

Education and Information for Self-Care

Patient and Public Involvement in the Research Process

Summary

Acknowledgments

References

CHAPTER 4: The Cochrane Skin Group

Background

The Cochrane Skin Group

Editorial Process: Join the Cochrane Skin Group and Publish a High-Impact Paper!

The Cochrane Library

The Role of Consumers

Impact of Our Reviews

References

Other Useful Resources

PART II: The Critical Appraisal Toolbox

CHAPTER 5: Formulating Well-Built Clinical Questions

Introduction

Tips for Building Well-Built Clinical Questions

The Advantages of Well-Built Clinical Questions

What Factors Are Important in Generating Well-Built Questions in a Dermatology Consultation?

References

CHAPTER 6: Finding the Best Evidence

Note

References

CHAPTER 7: The Hierarchy of Evidence

References

CHAPTER 8: Appraising Systematic Reviews and Meta-Analyses

Introduction

Asking a Clear Question

Sources of Evidence within a Systematic Review

The Hazards of “Quick” Searches

Publication and Selective Reporting Outcome Bias

Data Abstraction

Pooling Results

Interpretation of the Data

Overviews and Network Meta-Analysis

References

CHAPTER 9: How to Critically Appraise a Randomized Controlled Trial

The Place of Randomized Controlled Trials

Definitions of Quality, Validity, and Bias

How to Tell a Good Dermatological Randomized Controlled Trial from a Bad One

References

CHAPTER 10: Assessing and Explaining the Evidence on Harms of Medical Interventions

Introduction

Data Sources

Back to the Individual Patient

References

CHAPTER 11: How to Evaluate Diagnostic Tests

Introduction

Critical Appraisal of Diagnostic Studies

References

CHAPTER 12: What Makes a Good Case Series?

Introduction

Methodology of Case Series

Diagnosis

Inclusion and Exclusion Criteria

Informed Consent

Consecutive Cases

Natural Course of the Disease

Dosages

Outcome Measures

Patient Perception

Safety

Conclusions

Acknowledgments

References

CHAPTER 13: What Makes a Good Prevalence Survey?

Introduction

The Importance of Clear Reporting

Quality Criteria

Additional Criteria

Other Checklists and Scales

Conclusion

References

CHAPTER 14: Critical Appraisal of Pharmacoeconomic Studies

Introduction

Cost Analysis

Cost-Effectiveness Analysis

Cost–Utility Analysis

Cost–Benefit Analysis

Guidelines for Critical Appraisal of Pharmacoeconomic Studies

References

CHAPTER 15: Comparative Effectiveness Research: What It Is and How to Assess Its Quality

Why Do Comparative Effectiveness Research?

What Is Comparative Effectiveness Research?

Methods in Comparative Effectiveness Research

Assessing the Quality of Comparative Effectiveness Research

References

CHAPTER 16: Outcome Measures

Introduction

What Can We Do with Outcomes?

Outcomes in Dermatology and Future Directions

References

CHAPTER 17: Where Does Qualitative Research Fit Into Evidence-Based Dermatology?

Definitions

Qualitative Research and Evidence-Based Medicine

Methods

Critical Appraisal and Meta-Analysis

Final Remarks

References

Other Useful Resources

CHAPTER 18: Applying the Evidence Back to the Patient

Introduction

How Similar Are the Study Participants to My Patient?

Do the Outcomes Make Sense to Me?

Magnitude of Treatment Effects

Adverse Events

What Are the Patient's Values?

Conclusions

References

PART III: The Evidence

SECTION 1 Common Inflammatory Skin Diseases

CHAPTER 19: Acne Vulgaris

Background

Questions

References

CHAPTER 20: Papulopustular Rosacea

Background

Questions

References

CHAPTER 21: Perioral Dermatitis

Background

Questions

Acknowledgments

References

CHAPTER 22: Hand Eczema

Introduction

Questions

References

CHAPTER 23: The Primary Prevention of Atopic Dermatitis

Background

Questions

References

CHAPTER 24: Atopic Eczema

Coverage and Main Data Sources

Background

Questions

General Summary Observations on the Evidence Base for Atopic Eczema

Acknowledgments

References

CHAPTER 25: Seborrheic Dermatitis

Background

Questions

References

CHAPTER 26: Treatment of Psoriasis

Background

Topical Treatment of Chronic Plaque-Type Psoriasis

Phototherapy

Systemic Treatment of Chronic Plaque-Type Psoriasis

Note

References

CHAPTER 27: Lichen Planus

Background

Questions

Summary

References

CHAPTER 28: Acute Urticaria

Introduction

Background

Questions

References

CHAPTER 29: Chronic Urticaria

Background

Questions

References

SECTION 2 Skin Cancer, Moles, and Actinic Keratoses

CHAPTER 30: Primary Prevention of Skin Cancer

Background

Review of Evidence on Primary Prevention

Implications for Practice

Acknowledgments

References

CHAPTER 31: Treatment of Cutaneous Melanoma

Localized Disease

Metastatic Malignant Melanoma

References

CHAPTER 32: Treatment of Squamous Cell Carcinoma

Background

Prognosis

Questions

Evidence Summary

Implications for Clinical Practice

Acknowledgments

References

CHAPTER 33: Basal Cell Carcinoma

Background

Questions

References

CHAPTER 34: Primary Cutaneous T-cell Lymphoma

Background

Questions

References

CHAPTER 35: Actinic Keratosis and Bowen's Disease

Background

Questions

Diclofenac

Implications for Clinical Practice: Spontaneous Regression rates and Future Studies

Acknowledgments

Other Useful Resources

References

CHAPTER 36: Kaposi Sarcoma

Background

Questions

References

CHAPTER 37: Melanocytic Nevi

Background

Questions

Skin Self-Examination

References

SECTION 3 Infective Skin Diseases, Exanthems, and Infestations

CHAPTER 38: Local Treatments for Cutaneous Warts

Background

Results

References

CHAPTER 39: Molluscum Contagiosum

Background

Question

Implications for Clinical Practice

Acknowledgments

References

CHAPTER 40: Impetigo

Background

Questions

References

CHAPTER 41: Athlete's Foot

Background

Questions

References

CHAPTER 42: Pityriasis Versicolor

Background

Questions

References

CHAPTER 43: Onychomycosis

Background

Questions

General Comments

References

CHAPTER 44: Tinea Capitis

Background

Systemic Antifungal Therapy for Tinea Capitis in Children

Questions

References

CHAPTER 45: Deep Fungal Infections

Introduction

Mycetoma

Sporotrichosis

Chromoblastomycosis

The Endemic Mycoses

References

CHAPTER 46: Streptococcal Cellulitis/Erysipelas of the Lower Leg

Background

Questions

Acknowledgments

References

CHAPTER 47: Exanthematic Reactions

Background

Questions

References

CHAPTER 48: Herpes Simplex

Background

Questions

References

CHAPTER 49: Leprosy

Background

Questions

Acknowledgments

References

CHAPTER 50: Cutaneous Leishmaniasis

Background

Questions

Acknowledgments

References

CHAPTER 51: Scabies

Background

Context

Questions

References

CHAPTER 52: Head Lice

Background

Context

Questions

References

CHAPTER 53: Insect Bites and Stings

Background

Questions

Acknowledgment

References

SECTION 4: Disorders of Pigmentation

CHAPTER 54: Vitiligo

Background

Questions

References

CHAPTER 55: Melasma

Background

Questions

Implications of the Available Evidence

Acknowledgments

References

SECTION 5 Common Ailments with Significant Cosmetic Impact

CHAPTER 56: Male and Female Androgenetic Alopecia

Background

Questions

References

CHAPTER 57: Alopecia Areata

Background

Questions

References

CHAPTER 58: Evidence-Based Treatment of Hirsutism

Background

Questions

References

CHAPTER 59: Focal Hyperhidrosis

Background

Questions

Acknowledgments

Appendix 59A: Search Strategies

References

CHAPTER 60: Dermal Fillers

Background

Questions

Summary

References

CHAPTER 61: Reducing Mimic Wrinkles and Folds with Botulinum Toxin A

Background

Clinical Questions

Further Questions

Note

References

SECTION 6 Other Important Skin Disorders

CHAPTER 62: Cutaneous Lupus Erythematosus

Background

Questions

References

CHAPTER 63: Dermatomyositis

Background

Questions

Current Recommendations

References

CHAPTER 64: Acquired Subepidermal Bullous Diseases

Background

Bullous Pemphigoid

Questions