208,99 €
A growing awareness of the relationship between diet and health has led to an increasing demand for food
products that support health beyond simply providing basic nutrition. Digestive
health is the largest segment of the burgeoning functional food market worldwide. Incorporation of bioactive
oligosaccharides into foods can yield health benefits in the gastrointestinal
tract and other parts of the body that are linked via the immune system.
Because oligosaccharides can be added to a wide variety of foodstuffs, there is
much interest within the food industry in incorporating these functional
ingredients into healthy food products. Moreover, other areas such as
pharmaceuticals, bioenergy and environmental science can exploit the
physicochemical and physiological properties of bioactive oligosaccharides too.
There is therefore a considerable demand for a concentrated source of
information on the development and characterization of new oligosaccharides
with novel and/or improved bioactivities.
Food Oligosaccharides: Production, Analysis and Bioactivityis a comprehensive reference on the
naturally occurring and synthesised oligosaccharides, which will enable food
professionals to select and use these components in their products. It is
divided into three sections: (i) Production and bioactivity of
oligosaccharides, (ii) Analysis and (iii) Prebiotics in Food Formulation. The
book addresses classical and advanced techniques to structurally characterize and
quantitatively analyse food bioactive oligosaccharides. It also looks at practical
issues faced by food industry professionals seeking to incorporate prebiotic
oligosaccharides into food products, including the effects of processing on
prebiotic bioavailability. This book is essential reading for food researchers
and professionals, nutritionists and product developers working in the food
industry, and students of Food Science with an interest in functional foods.
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Library of Congress Cataloging-in-Publication Data
Food oligosaccharides : production, analysis and bioactivity / [edited by] F. Javier Moreno and M. Luz Sanz.
pages cm
Includes bibliographical references and index.
ISBN 978-1-118-42649-4 (cloth)
1. Oligosaccharides. 2. Oligosaccharides–Biotechnology. 3. Food–Carbohydrate content. I. Moreno, F. Javier, editor of compilation. II. Sanz, M. Luz (Maria Luz), editor of compilation.
QP702.O44F66 2014
572′.565–dc23
2013043858
A catalogue record for this book is available from the British Library.
Wiley also publishes its books in a variety of electronic formats. Some content that appears in print may not be available in electronic books.
Cover images: Dairy products © iStock/SergeyZavalnyuk, Ball and stick model of a lactose molecule © Shutterstock/Petarg, Bacteria © Shutterstock
Cover design by www.hisandhersdesign.co.uk
Accelerating New Food Product Design and Development
(Jacqueline H. Beckley, Elizabeth J. Topp, M. Michele Foley, J.C. Huang, and Witoon Prinyawiwatkul)
Advances in Dairy Ingredients
(Geoffrey W. Smithers and Mary Ann Augustin)
Bioactive Compounds from Marine Foods: Plant and Animal Sources
(Blanca Hernández-Ledesma and Miguel Herrero)
Bioactive Proteins and Peptides as Functional Foods and Nutraceuticals
(Yoshinori Mine, Eunice Li-Chan, and Bo Jiang)
Biofilms in the Food Environment
(Hans P. Blaschek, Hua H. Wang, and Meredith E. Agle)
Calorimetry in Food Processing: Analysis and Design of Food Systems
(Gönül Kaletunç)
Coffee: Emerging Health Effects and Disease Prevention
(YiFang Chu)
Food Carbohydrate Chemistry
(Ronald E. Wrolstad)
Food Ingredients for the Global Market
(Yao-Wen Huang and Claire L. Kruger)
Food Irradiation Research and Technology
, Second Edition (Christoper H. Sommers and Xuetong Fan)
Foodborne Pathogens in the Food Processing Environment: Sources, Detection and Control
(Sadhana Ravishankar, Vijay K. Juneja, and Divya Jaroni)
Food Texture Design and Optimization
(Yadunandan Dar and Joseph Light)
High Pressure Processing of Foods
(Christopher J. Doona and Florence E. Feeherry)
Hydrocolloids in Food Processing
(Thomas R. Laaman)
Improving Import Food Safety
(Wayne C. Ellefson, Lorna Zach, and Darryl Sullivan)
Innovative Food Processing Technologies: Advances in Multiphysics Simulation
(Kai Knoerzer, Pablo Juliano, Peter Roupas, and Cornelis Versteeg)
Mathematical and Statistical Methods in Food Science and Technology
(Daniel Granato and Gastón Ares)
Microbial Safety of Fresh Produce
(Xuetong Fan, Brendan A. Niemira, Christopher J. Doona, Florence E. Feeherry, and Robert B. Gravani)
Microbiology and Technology of Fermented Foods
(Robert W. Hutkins)
Multiphysics Simulation of Emerging Food Processing Technologies
(Kai Knoerzer, Pablo Juliano, Peter Roupas, and Cornelis Versteeg)
Multivariate and Probabilistic Analyses of Sensory Science Problems
(Jean-François Meullenet, Rui Xiong, and Christopher J. Findlay)
Nanoscience and Nanotechnology in Food Systems
(Hongda Chen)
Natural Food Flavors and Colorants
(Mathew Attokaran)
Nondestructive Testing of Food Quality
(Joseph Irudayaraj and Christoph Reh)
Nondigestible Carbohydrates and Digestive Health
(Teresa M. Paeschke and William R. Aimutis)
Nonthermal Processing Technologies for Food
(Howard Q. Zhang, Gustavo V. Barbosa-Cánovas, V.M. Balasubramaniam, C. Patrick Dunne, Daniel F. Farkas, and James T.C. Yuan)
Nutraceuticals, Glycemic Health and Type 2 Diabetes
(Vijai K. Pasupuleti and James W. Anderson)
Organic Meat Production and Processing
(Steven C. Ricke, Ellen J. Van Loo, Michael G. Johnson, and Corliss A. O′Bryan)
Packaging for Nonthermal Processing of Food
(Jung H. Han)
Practical Ethics for Food Professionals: Ethics in Research, Education and the Workplace
(J. Peter Clark and Christopher Ritson)
Preharvest and Postharvest Food Safety: Contemporary Issues and Future Directions
(Ross C. Beier, Suresh D. Pillai, and Timothy D. Phillips, Editors; Richard L. Ziprin, Associate Editor)
Processing and Nutrition of Fats and Oils
(Ernesto M. Hernandez and Afaf Kamal-Eldin)
Processing Organic Foods for the Global Market
(Gwendolyn V. Wyard, Anne Plotto, Jessica Walden, and Kathryn Schuett)
Regulation of Functional Foods and Nutraceuticals: A Global Perspective
(Clare M. Hasler)
Resistant Starch: Sources, Applications and Health Benefits
(Yong-Cheng Shi and Clodualdo Maningat)
Sensory and Consumer Research in Food Product Design and Development
(Howard R. Moskowitz, Jacqueline H. Beckley, and Anna V.A. Resurreccion)
Sustainability in the Food Industry
(Cheryl J. Baldwin)
Thermal Processing of Foods: Control and Automation
(K.P. Sandeep)
Trait-Modified Oils in Foods
(Frank T. Orthoefer and Gary R. List)
Water Activity in Foods: Fundamentals and Applications
(Gustavo V. Barbosa-Cánovas, Anthony J. Fontana Jr., Shelly J. Schmidt, and Theodore P. Labuza)
Whey Processing, Functionality and Health Benefits
(Charles I. Onwulata and Peter J. Huth)
Contributors
Preface
Part I Production and Bioactivity of Oligosaccharides
Part I.I Naturally Occurring Oligosaccharides
1 Bioactivity of Human Milk Oligosaccharides
1.1 Introduction
1.2 Structural uniqueness of human milk oligosaccharides
1.3 Human milk oligosaccharides and their functions in the gastrointestinal tract
1.4 Human milk oligosaccharides and systemic effects
1.5 Human milk oligosaccharides and studies in animals and humans
1.6 Conclusion and perspective
Acknowledgment
References
2 Production and Bioactivity of Bovine Milk Oligosaccharides
2.1 Introduction
2.2 Bovine milk oligosaccharides’ composition
2.3 Bovine milk oligosaccharides' concentration
2.4 Resistance to digestion
2.5 Oligosaccharides' biological activities
2.6 Isolation approaches
2.7 Conclusion
Acknowledgments
References
3 Production and Bioactivity of Oligosaccharides in Plant Foods
3.1 Introduction
3.2 Chemical structure and natural occurrence of oligosaccharides in plant foods
3.3 Production of naturally occurring plant oligosaccharides
3.4 Scientific evidence on the bioefficacy of plant oligosaccharides and mechanisms of action
3.5 Conclusions and future perspectives
References
4 Production and Bioactivity of Oligosaccharides from Chicory Roots
4.1 Production of oligosaccharides from chicory roots
4.2 Bioactivity of oligosaccharides from chicory roots
4.3 Future trends
4.4 Conclusions
References
5 Production and Bioactivity of Pectic Oligosaccharides from Fruit and Vegetable Biomass
5.1 Production of pectic oligosaccharides
5.2 Bioactivity of pectic oligosaccharides
5.3 Conclusions
References
6 Production and Bioactivity of Oligosaccharides from Biomass Hemicelluloses
6.1 Hemicelluloses: general aspects
6.2 Manufacture of oligosaccharides from hemicellulosic polymers
6.3 Properties of hemicellulose-derived oligosaccharides
6.4 Conclusion
References
7 Starch Hydrolysis Products with Physiological Activity in Humans
7.1 Introduction
7.2 Starch degradation may yield minor saccharides with physiological activity
7.3 Physiological activity of starch hydrolysis products
7.4 Concluding remarks
References
8 Biosynthesis and Bioactivity of Exopolysaccharides Produced by Probiotic Bacteria
8.1 Bacterial exopolysaccharides
8.2 Biosynthesis of exopolysaccharides in
Lactobacillus
and
Bifidobacterium
8.3 Production and purification of exopolysaccharides
8.4 Bioactivity of exopolysaccharides from probiotics
8.5 Concluding remark and future trends
Acknowledgments
References
Part I.II Non-Naturally Occurring Oligosaccharides
9 Production and Bioactivity of Oligosaccharides Derived from Lactose
9.1 Introduction
9.2 Mono- and disaccharides
9.3 Lactosucrose
9.4 Galactooligosaccharides
9.5 Other oligosaccharides
9.6 Purification of carbohydrates derived from lactose
9.7 Conclusions
Acknowledgments
References
10 Production and Bioactivity of Glucooligosaccharides and Glucosides Synthesized using Glucansucrases
10.1 Glucooligosaccharides from lactic acid bacteria
10.2 Glucan and glucooligosaccharides synthesis by glucansucrases
10.3 Production of glucooligosaccharides
10.4 Bioactivities of glucan and glucooligosaccharides
10.5 (Oligo)glucosides synthesized by glucansucrases and their functionalities
10.6 Conclusions
Acknowledgments
References
11 Production and Bioactivity of Fructan-Type Oligosaccharides
11.1 Introduction
11.2 Enzymatic synthesis
11.3 Functional properties of fructan-type oligosaccharides
11.4 Conclusions
Acknowledgments
References
12 Application of Immobilized Enzymes for the Synthesis of Bioactive Fructooligosaccharides
12.1 Enzyme immobilization
12.2 Immobilized biocatalysts for the production of fructooligosaccharides
12.3 Production of fructooligosaccharides with a covalently immobilized fructosyltransferase
12.4 Production of fructooligosaccharides with alginate-entrapped fructosyltransferases
12.5 Conclusions and future trends
Acknowledgments
References
Part I.III Assessment of Bioactivity
13
In Vitro
Assessment of the Bioactivity of Food Oligosaccharides
13.1 Introduction
13.2 Gut microbiota
13.3 Interaction with the host
13.4
In vitro
fermentation models of the gut to study bioactivity of oligosaccharides
13.5 Applications of
in vitro
fermentation models to study the effect of oligosaccharides on the gut microbiome
13.6 Mechanistic studies using
13
C-labeled oligosaccharides and fibers
13.7
In vitro
cell culture systems
13.8 Conclusions
13.9 Future perspectives
Acknowledgments
References
14
In Vivo
Assessment of the Bioactivity of Food Oligosaccharides
14.1 The prebiotic concept
14.2
In vivo
assessment of dietary oligosaccharides as prebiotics
14.3 Concluding remarks
Acknowledgments
References
Part II Analysis
15 Fractionation of Food Bioactive Oligosaccharides
15.1 Introduction
15.2 Membrane techniques
15.3 Chromatographic techniques
15.4 Fractionation techniques using solvents
15.5 Microbiological and enzymatic treatments
15.6 Conclusions
Acknowledgments
References
16 Classical Methods for Food Carbohydrate Analysis
16.1 Introduction
16.2 Sample preparation and purification
16.3 Classical methods for total sugar analysis
16.4 Classical methods for monosaccharide determination
16.5 Classical methods for structure characterization of polysaccharides
16.6 Some physical methods for carbohydrate analysis
16.7 Classical methods for dietary fiber analysis
16.8 Conclusions
References
17 Infrared Spectroscopic Analysis of Food Carbohydrates
17.1 Introduction
17.2 Monosaccharides
17.3 Oligosaccharides
17.4 Applications
17.5 Concluding remarks
References
18 Structural Analysis of Carbohydrates by Nuclear Magnetic Resonance Spectroscopy and Molecular Simulations: Application to Human Milk Oligosaccharides
18.1 Introduction
18.2 Nuclear Magnetic Resonance spectroscopy
18.3 Molecular dynamics computer simulations
18.4 Three-dimensional structures of human milk oligosaccharides
18.5 Concluding remarks
Acknowledgments
References
19 Analysis of Food Bioactive Oligosaccharides by Thin-Layer Chromatography
19.1 Introduction
19.2 Thin-layer chromatography
19.3 Thin-layer chromatography analysis of food bioactive oligosaccharides
19.4 Conclusions
References
20 Gas Chromatographic Analysis of Food Bioactive Oligosaccharides
20.1 Introduction
20.2 Sample preparation
20.3 Instrumentation
20.4 Advanced analysis by comprehensive two-dimensional gas chromatography (GC×GC)
20.5 Conclusions
Acknowledgments
References
21 Analysis of Bioactive Food-Sourced Oligosaccharides by High-Performance Liquid Chromatography
21.1 Introduction
21.2 Derivatization of oligosaccharides
21.3 High-performance liquid chromatography analysis of bioactive food sourced oligosaccharides
21.4 Application of high-performance liquid chromatography for the separation of bioactive food sourced oligosaccharides
21.5 Novel analytical methods
21.6 Conclusion
Acknowledgments
References
22 Capillary Electrophoresis and Related Techniques for the Analysis of Bioactive Oligosaccharides
22.1 Introduction
22.2 Capillary electrophoresis analysis of functional oligosaccharides
22.3 Capillary electrophoresis analysis of glycosaminoglycan-derived oligosaccharides
22.4 Capillary electrophoresis analysis of oligosaccharides derived from glycoproteins
22.5 Conclusions
References
23 Mass Spectrometric Analysis of Food Bioactive Oligosaccharides
23.1 Introduction
23.2 Instrumentation for mass spectrometric analysis of oligosaccharides
23.3 Fragmentation techniques, processes and nomenclature
23.4 Applications to analysis of food bioactive oligosaccharides
23.5 Strategies, challenges, and conclusion
References
Part III Prebiotics in Food Formulation
24 Nutritional and Technological Benefits of Inulin-Type Oligosaccharides
24.1 Introduction
24.2 Nutritional aspects of chicory inulin and oligofructose
24.3 Technical properties of chicory inulin and oligofructose
24.4 Technical functionality in food applications
24.5 Conclusions
References
25 Industrial Applications of Galactooligosaccharides
25.1 Introduction
25.2 Global market development for galactooligosaccharides
25.3 Nutritional benefits of galactooligosaccharides for infants and young children
25.4 Legislative aspects and safety of galactooligosaccharides
25.5 Galactooligosaccharide products
25.6 Applications of galactooligosaccharides
25.7 Stability of galactooligosaccharides
25.8 Concluding remarks and future developments
References
26 Successful Product Launch: Combining Industrial Technologies with Adapted Health Ingredients
26.1 Developing new foods: the health dimension
26.2 A global approach to successful food conception, applied to the case of digestive health
26.3 The ingredients and the formulation: practical aspects of the incorporation of nondigestible oligosaccharides
26.4 Elaborating new food products with nondigestible oligosaccharides
26.5 What are the key success factors? Synthesis and comments from an expert chef
26.6 Conclusion
References
Epilogue: Concluding Thoughts on Food Bioactive Oligosaccharides
Index
Chapter 1
Table 1.1
Table 1.2
Table 1.3
Table 1.4a
Table 1.4b
Table 1.5
Table 1.5
Table 1.5
Table 1.6
Chapter 2
Table 2.1
Chapter 3
Table 3.1
Table 3.2
Table 3.3
Chapter 4
Table 4.1
Table 4.2
Chapter 8
Table 8.1
Chapter 9
Table 9.1
Table 9.2
Chapter 10
Table 10.1
Table 10.2
Chapter 11
Table 11.1
Table 11.2
Table 11.3
Chapter 12
Table 12.1
Table 12.2
Chapter 14
Table 14.1
Table 14.2
Table 14.3
Chapter 15
Table 15.1
Table 15.2
Chapter 16
Table 16.1
Chapter 17
Table 17.1
Table 17.2
Table 17.3
Table 17.4
Table 17.5
Chapter 19
Table 19.1
Table 19.2
Table 19.3
Table 19.4
Chapter 20
Table 20.1
Table 20.2
Table 20.3
Table 20.4
Table 20.5
Table 20.6
Chapter 21
Table 21.1
Table 21.2
Chapter 22
Table 22.1
Table 22.2
Chapter 23
Table 23.1
Chapter 24
Table 24.1
Table 24.2
Table 24.3
Table 24.4
Table 24.5
Table 24.6
Table 24.7
Table 24.8
Table 24.9
Chapter 25
Table 25.1
Table 25.2
Table 25.3
Table 25.4
Chapter 26
Table 26.1
Table 26.2
Table 26.3
Table 26.4
Table 26.5
Table 26.6
Table 26.7
Table 26.8
Table 26.9
Table 26.10
Table 26.11
Table 26.12
Table 26.13
Table 26.14
Table 26.15
Table 26.16
Table 26.17
Table 26.18
Table 26.19
Cover
Table of Contents
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Agemans, Arnaud
BENEO GmbH Obrigheim Germany
Alonso, José Luis
Chemical Engineering Department, University of Vigo (Campus Ourense) Ourense Spain; CITI Ourense Spain
Arrizón, Javier
Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco, A.C. Guadalajara Jalisco Mexico
Ballesteros, Antonio O.
Instituto de Catálisis y Petroleoquímica, CSIC Madrid Spain
Barile, Daniela
Department of Food Science and Technology University of California Davis, CA USA; Foods for Health Institute University of California Davis, CA USA
Caers, Wim
BENEO GmbH Obrigheim Germany
Carrero-Carralero, Cipriano
