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Table of Contents
Cover
Dedication
Title page
Copyright page
Preface
Preface to the Fifth Edition
Contributors
List of Abbreviations
PART I: Vascular Imaging Techniques and Physiologic Testing
CHAPTER 1 Arterial and Venous Duplex Scanning
Ultrasound basics
Carotid and vertebral-artery duplex scanning
Peripheral artery duplex scanning
Visceral arteries
Venous disease
Chronic venous insufficiency
Selected miscellaneous examinations
CHAPTER 2 Duplex Arteriography for Lower Extremity Revascularization
Materials and methods
Results
Conclusions
CHAPTER 3 Fundamentals of Angiography
Basic concepts of angiographic imaging
Angiographic equipment
Contrast agents
Sources of error with angiography
Basics of radiation safety
CHAPTER 4 Arteriographic Patterns of Atherosclerotic Occlusive Disease of the Lower Extremity
Methods of study
Aortoiliac patterns
Femoropopliteal patterns
Tibioperoneal patterns
Collateral circulation in occlusive patterns of femoropopliteal and tibioperoneal segments
CHAPTER 5 Computed Tomography in Vascular Disease
Introduction
Basic principles
Helical, multidetector and dual source computed tomography
Vascular techniques and protocols
Interpretation principles
Clinical applications
Comments
Future directions: plaque imaging
CHAPTER 6 Magnetic Resonance Angiography
Introduction
Principles
Clinical applications
Neuroimaging
Conclusions
CHAPTER 7 Intravascular Ultrasound Imaging
Device development and imaging configurations
Intravascular ultrasound imaging techniques
Clinical utility of intravascular ultrasound
PART II: Basic Science in Vascular Diseases
CHAPTER 8 Hemodynamics of Vascular Disease: Applications to Diagnosis and Treatment
Normal blood flow
Arterial stenoses
Stenosis as part of a larger arterial circuit
Bypass grafts
Conclusions
CHAPTER 9 Atherosclerosis: Biological and Surgical Considerations
Historical perspective
Epidemiology
Normal anatomy
Theories of atherosclerosis
Morphology and hemodynamics
Stages of atherosclerosis
Risk factors
Therapeutic implications
CHAPTER 10 Neointimal Hyperplasia: Basic Considerations
What is neointimal hyperplasia?
Pathophysiology of NIH
Neointimal hyperplasia as a response to injury
Interventions to treat neointimal hyperplasia
Acknowledgments
CHAPTER 11 Therapeutic Angiogenesis
Introduction
Biology of vessel formation
Therapeutic angiogenesis
Stem cell therapy
Summary and future perspective
Acknowledgements
CHAPTER 12 Thrombogenesis and Thrombolysis
Normal coagulation and anticoagulation
Medications
Disorders of coagulation
Perioperative considerations
Acknowledgments
CHAPTER 13 Etiology of Abdominal Aortic Aneurysms
Definitions
Epidemiology—prevalence and mortality
Risk factors
Family history
Molecular genetics
Atherosclerosis and abdominal aortic aneurysms
Structural physiology
Structural pathophysiology
Changes related to normal aging
Enzymatic degradation
Inflammation
Autoimmunity
Infection
Abdominal arterial aneurysms and popliteal artery aneurysms
Conclusion
CHAPTER 14 An Evidence-based Approach to Cardiopulmonary Risk Assessment for Vascular Surgery Procedures
Cardiac evaluation
Cardiac risk assessment guidelines
Respiratory failure
Conclusion
PART III: Basic Open Vascular Techniques
CHAPTER 15 Vascular Sutures and Anastomoses
Exposure and mobilization of arteries
Clamping of an artery
Arterial ligation
Arteriotomy
Vascular anastomoses
CHAPTER 16 Patch-graft Angioplasty
Indications
Patch-graft material
Methods and techniques of patching
Conclusion
CHAPTER 17 Endarterectomy
Principles of endarterectomy
Semiclosed endarterectomv
Open endarterectomy
Combined procedures
Comments: endarterectomy-versus-percutaneous balloon catheterization
CHAPTER 18 Balloon Angioplasty of Peripheral Arteries and Veins
History
Pathophysiology
Indications
Technique
Assessment of results
Complications
Recommended follow-up and surveillance
CHAPTER 19 Stents for Peripheral Arteries and Veins
General principles of vascular stents
Biologic response to intravascular stent placement
Indications for stent placement
Relative contraindications to stent placement
Complications
Stents in iliac arteries
Stents in femoropopliteal arteries
Infrapopliteal stents
Stents in peripheral veins
Future stents
Summary
CHAPTER 20 Thrombolytic Therapy for Peripheral Arterial and Venous Thrombosis
Plasmin and the fibrinolytic system
Thrombolytic agents
Arterial thrombolysis
Venous thrombolysis
Conclusion
PART IV: Open Surgical Exposure of Arteries
CHAPTER 21 Exposure of the Carotid Artery
Anatomic review
Technique of carotid exposure
CHAPTER 22 The Vertebrobasilar System: Anatomy and Surgical Exposure
Exposure of the vertebral artery
CHAPTER 23 Trans-sternal Exposure of the Great Vessels of the Aortic Arch
Left subclavian artery
Innominate, right subclavian, and common carotid arteries
Conclusions
CHAPTER 24 Extrathoracic Surgical Exposure for Distal Revascularization of Brachiocephalic Branches
Historical background
Clinical background
Carotid–subclavian bypass technique
AxiIIary–axillary bypass graft technique
Subclavian–subclavian bypass
Conclusion
CHAPTER 25 Open Surgical Exposure of Upper Extremity Arteries
Exposure of subclavian artery
Exposure of axillary artery
Exposure of brachial artery
Exposure of radial and ulnar arteries
Exposure of carotid artery
CHAPTER 26 Transperitoneal Exposure of Abdominal Aorta and Iliac Arteries
Anatomic review
Physiopathologic considerations in aortic surgery
Transperitoneal exposure of iliac arteries
CHAPTER 27 Retroperitoneal Exposure of Abdominal Aorta
Retroperitoneal infrarenal aortic exposure
Retroperitoneal approach for juxtarenal and suprarenal aortic exposure
Pitfalls of retroperitoneal aortic reconstruction
CHAPTER 28 Retroperitoneal Exposure of Iliac Arteries
Anatomic review
Exposure of external iliac artery
Combined iliac and femoral exposures
CHAPTER 29 Open Surgical Exposures of Arteries in the Lower Extremity
Femoral artery
Popliteal artery
Leg arteries
Dorsalis pedis
Plantar arteries
PART V: Cerebrovascular Insufficiency
CHAPTER 30 Medical Management of Carotid Artery Disease
Objectives of medical management
Hyperhomocysteinemia
Antithrombotic therapy
Optimal medical treatment: “classic” versus contemporary
Conclusion and recommendations
CHAPTER 31 Carotid Endarterectomy: Indications, Techniques, and Results
Indications for CEA
Operative technique
Results
Perioperative complications
Long-term results of CEA
Reoperative carotid endarterectomy
CHAPTER 32 Eversion Carotid Endarterectomy
Introduction
Methods
Results
Conclusion
CHAPTER 33 Carotid Stenting: Indications, Techniques, and Results
Current indications
Current techniques
Results, contraindications, and future directions
CHAPTER 34 Cerebral Protection Devices During Carotid Stenting
Introduction
The debate around cerebral protection devices
Types of cerebral protection devices
Device selection
Conclusion
CHAPTER 35 Vertebrobasilar Disease: Surgical Management
Low-flow mechanism
Embolic mechanism
Mixed etiology
Pathology of the vertebral artery
Syndrome of vertebrobasilar ischemia
Surgical management
CHAPTER 36 Nonatherosclerotic Cerebrovascular Disease
Inflammatory processes
Temporal arteritis
Takayasu’s arteritis
Behçet’s disease
Elongation and Coiling of the Carotid Artery
Aneurysms of the extracranial carotid artery
Carotid dissection
Fibromuscular disease of the carotid artery
Carotid body tumors
Injuries to the carotid artery from radiation
Recurrent carotid stenosis after endarterectomy
PART VI: Aortic and Iliac Aneurysms
CHAPTER 37 Indications, Techniques and Results of Open Repair of Ascending and Transverse Aortic Arch Aneurysms
Introduction
History
Diagnosis
Indications for surgery
Preoperative assessment
Operative technique, general
Results of general technique
Extensive aneurysm of the aorta: elephant trunk
Conclusion
Acknowledgments
CHAPTER 38 Hybrid Repair of Aortic Arch Aneurysms
Introduction
Anatomic considerations
Pathology
Natural history
Preoperative evaluation
Treatment
Hybrid approaches
CHAPTER 39 Endovascular Management of Thoracic Aortic Aneurysms and Dissections
Introduction
Endografts for TEVAR
Indications for TEVAR
Anatomic considerations for TEVAR
Preoperative planning
Operative approaches and technical considerations
Results of TEVAR
Complications of TEVAR
Endovascular treatment of type-B aortic dissection
Conclusion
CHAPTER 40 Open Repair of Thoracoabdominal Aortic Aneurysms
Indications for operation
Preoperative evaluation
Open surgical repair
Postoperative management
Outcomes
Surveillance for additional aortic disease
Acknowledgments
CHAPTER 41 Open Repair of Abdominal Aortic Aneurysms
Introduction
Etiology and pathogenesis
Risk factors
Risk of aneurysm rupture
Clinical presentation
Diagnosis
Preoperative evaluation
Treatment
Uncommon aneursyms
Surgical timing
Perioperative management
Perioperative outcomes
Postoperative complications
Conclusions
CHAPTER 42 Endovascular Repair of Infrarenal Abdominal Aortic Aneurysms
Introduction
Endograft design
Aortoiliac morphology: selection and planning
Anesthetic considerations
The endovascular suite
Surgical technique: arterial access
Endovascular technique: stent-graft deployment
Adjunctive procedures
Renal-artery intervention
Outcomes
Surveillance
Repeat intervention
Ruptured aortic aneurysms
Future direction
CHAPTER 43 Fenestrated and Branched Stent Grafts for the Treatment of Complex Aortic Aneurysms
Introduction
Historical aspects
Current techniques of fenestrated and branched endografts
Technical aspects
Results
Summary
CHAPTER 44 Endovascular Treatment of Ruptured Infrarenal Aortic and Iliac Aneurysms
Obstacles to use of endovascular grafts in the ruptured aneurysm setting
Suitable endografts for endovascular repair in the rAAA setting
Early experience with endovascular treatment of rAAAs
Hypothesis regarding endovascular treatment of rAAAs and current management plan
Control of bleeding and blood pressure: restricted resuscitation or hypotensive hemostasis and proximal balloon control
Experience with endovascular treatment of rAAAs
Abdominal compartment syndrome
Collected world experience with endovascular graft treatment of rAAAS
Advantages of endovascular treatment of rAAAs
Discussion
CHAPTER 45 Open Surgical Treatment of Isolated Iliac Aneurysms
Incidence
Surgical management
CHAPTER 46 Endovascular Grafts in the Treatment of Isolated Iliac Aneurysms
Methods for endovascular graft repair
Surveillance considerations for isolated iliac aneurysms treated endovascularly
Conclusions
CHAPTER 47 Infected Aortic Grafts: General Considerations and Techniques
Prevention of aortic-graft infections
Clinical presentation
Diagnosis
Treatment
Conclusion
CHAPTER 48 Para-anastomotic Aortic Aneurysms: General Considerations and Techniques
Incidence of para-anastomotic aortic aneurysms
True para-anastomotic aortic aneurysms
False para-anastomotic aortic aneurysms
Infected para-anastomotic aortic aneurysms
Presentation
Management
Operative techniques and results
Endovascular treatment of para-anastomotic aortic aneurysms
Selection of operative approach
Surveillance
PART VII: Visceral Vessels
CHAPTER 49 Surgery of the Celiac Artery for Occlusive Disease and Arcuate Ligament Syndrome
Surgical anatomy of the celiac trunk and its branches
Occlusive disease of the celiac artery
Surgical bypass for visceral occlusive disease
Median arcuate ligament syndrome
Conclusion
CHAPTER 50 Management of Acute and Chronic Mesenteric Ischemia
Historical background
Acute mesenteric-artery ischemia
Mesenteric venous thrombosis
Chronic mesenteric-artery ischemia
Conclusion
CHAPTER 51 Endovascular Treatment of Mesenteric Occlusive Disease
Introduction
Pathophysiology and anatomy
Types of mesenteric lschemia
Clinical presentation
Workup
Endovascular treatment
Endovascular technique
Treatment of celiac artery compression syndrome
Clinical data
Other considerations
Conclusion
CHAPTER 52 Renal Artery Revascularization
Background
Physiology of renovascular hypertension
Clinical diagnosis of renovascular hypertension
Laboratory and radiologic diagnosis of renovascular hypertension
Endovascular treatment of renovascular disease
Operative management
Surgical techniques for renal artery reconstruction
Renal artery aneurysm repair
Results of renal artery reconstruction
CHAPTER 53 Renal Artery Fibrodysplasia and Renovascular Hypertension
Consequences of fibrodysplastic renovascular disease
Types of renal artery fibrodysplasia
Diagnosis of fibrodysplastic renovascular hypertension
Treatment
CHAPTER 54 Visceral Artery Aneurysms
Splenic artery aneurysm
Hepatic artery aneurysm
Superior mesenteric artery aneurysm
Celiac artery aneurysm
Gastroduodenal and pancreaticoduodenal aneurysms
Gastric and gastroepiploic artery aneurysm
Rare visceral artery aneurysms
Summary
PART VIII: Lower Extremity Occlusive and Non-Occlusive Arterial Disease
CHAPTER 55 Acute Arterial Occlusion of the Lower Extremities
Demographics and pathophysiology
Diagnosis
Therapeutic alternatives
Summary
CHAPTER 56 Aortoiliac Occlusive Disease
Clinical manifestations
Diagnosis
Arteriography
Imaging alternatives
Hemodynamic assessment of multilevel disease
Indications for operation
Surgical treatment
Direct operative procedures
The operative procedure
Special considerations
Results of direct aortoiliofemoral reconstruction
Postoperative complications
Conclusions
CHAPTER 57 Endovascular Treatment of Aortoiliac Artery Stenosis and Occlusions
Introduction
Presentation
Patient management
Procedural details
Outcomes
Summary
CHAPTER 58 Infrainguinal Arterial Disease
Historical perspective
The extent of the problem
The economics of failed limb salvage
Clinical assessment
Clinical classification of infrainguinal occlusive disease
Anatomic classification
Investigations
Management options
On the horizon
Conclusions
CHAPTER 59 Bypasses to Plantar Arteries and Other Branches of Tibial Arteries
Introduction
Anatomic exposure and techniques
Results
Conclusion
CHAPTER 60 Role of Surgical Options for Critical Lower Limb Ischemia
Toe and foot amputations, debridements, and conservative treatment
History of aggressive approach to limb salvage in patients with critical ischemia due to arteriosclerosis and evolution of the relationship between open bypass surgery and angiographic techniques and endovascular treatments
Early use of endovascular techniques (angioplasty and stenting) with bypass surgery
Current and future relationship between endovascular treatments and open bypass surgery
Specific open surgical revascularization procedures
Newer techniques for redo procedures after failed bypasses: thrombectomy and total or partial rescue of a failed ptfe bypass or a totally new bypass
Conclusions
CHAPTER 61 Adjuvant Surgical Techniques for Limb Salvage
Alternative autogenous conduit
Prosthetic conduit
Adjuvant clinical techniques
Allograft
CHAPTER 62 Endovascular Treatment of Infrapopliteal Arteries
Introduction
Clinical and anatomic issues in endovascular treatment of the infrapopliteal arteries
Techniques and specific tips for angioplasty and stenting of the infrapopliteal arteries
Results of endovascular treatment
Other options in the endovascular treatment of infrapopliteal lesion
Strategy in endovascular treatment of the infrapopliteal arteries
Summary
CHAPTER 63 Popliteal Artery Aneurysms
Historical background
Epidemiology
Etiology
Clinical presentation
Diagnostic evaluation
Indications for repair
Open surgical techniques
Endovascular repair
Results
CHAPTER 64 Endovascular Treatment of Popliteal Artery Aneurysms: The Role of Stent-Grafts and Thrombolysis
Introduction
Endovascular popliteal artery aneurysm repair
Thrombolysis
Conclusion
CHAPTER 65 Duplex-guided Balloon Angioplasty for Infrainguinal Arterial Occlusive and Aneurysmal Disease
Introduction
Duplex-guided infrainguinal arterial angioplasties
Duplex-guided endovascular repair of popliteal artery aneurysms
Conclusion
CHAPTER 66 Extra-anatomic Bypasses
Conventional extra-anatomic bypasses
Axillobifemoral bypass
Extended extra-anatomic bypasses
CHAPTER 67 Infected Extracavitary Prosthetic Grafts
Presentation and diagnosis
Management
Conclusions
CHAPTER 68 Popliteal Entrapment and Chronic Compartment Syndrome: Unusual Causes for Claudication in Young Adults
Popliteal entrapment
Diagnosis
Treatment
Summary
Chronic compartment syndrome
Treatment
Summary
CHAPTER 69 Lumbar Sympathectomy: Current Indications and Techniques
Introduction
Physiologic consequences
Assessment of lumbar sympathetic block
Lumbar sympathetic block techniques
Chemical lumbar sympathectomy
Clinical indications and results
CHAPTER 70 Nonatherosclerotic Diseases of Small Arteries
Small and medium vessels
Acute thrombosis of small arteries
Collagen diseases (immune arteritis)
Vasospastic diseases
Mixed organic and vasospastic diseases
Hematologic disorders
CHAPTER 71 Intraoperative Assessment and Postoperative Surveillance of Vascular Reconstructions
Intraprocedural assessment
Surveillance beyond the procedure room
Summary
PART IX: Vascular Trauma
CHAPTER 72 Vascular Trauma
General operative principles
Vascular injuries in specific anatomic locations
Peripheral vascular trauma
Special management problems
CHAPTER 73 Ankle and Foot Fasciotomy for Compartment Syndrome of the Foot
Clinical presentation
Signs and symptoms
The role of compartment pressure measurements
Compartments of the foot
Foot fasciotomy
Ankle fasciotomy
Approach to extended ankle and foot fasciotomy
Results
Conclusion
CHAPTER 74 Post-traumatic Pain Syndrome: Complex Regional Pain Syndrome
Incidence/etiology
Classification/terminology
Summary of the key features of CRPS
Syndrome types
Pathogenesis
Clinical presentation
Symptoms and signs
Comprehensive adjunctive clinical tests
Diagnostic evaluation
Diagnostic sympathetic block
Treatment
Sympathectomy
Overall results of treating CRPS
PART X: Upper Extremity Vascular Disease
CHAPTER 75 Vasospastic Disease of the Upper Extremity: Primary Raynaud’s Syndrome
Introduction
Epidemiology
Pathogenesis
Risk factors
Clinical presentation
Laboratory testing
Treatment
CHAPTER 76 Arterial Surgery of the Upper Extremity
Clinical evaluation
Diagnosis
Proximal arterial lesions
Distal arterial lesions
Aneurysms of upper-extremity arteries
Treatment
CHAPTER 77 Neurogenic Thoracic Outlet Syndrome and Pectoralis Minor Syndrome
Historical background
Types of TOS
Anatomy
Etiology
What’s new? NPMS
Histopathology
Clinical manifestations
Diagnostic tests
Conservative treatment
Surgical treatment
Surgical techniques
Complications of surgery
Results of treatment
Pathophysiology
CHAPTER 78 Venous Thoracic Outlet Syndrome
Introduction
Anatomy
Pathophysiology
Presentation
Diagnosis
Treatment
Prognosis
CHAPTER 79 Arterial Thoracic Outlet Syndrome
Historical background
Clinical background
The subclavian artery
Clinical manifestations
Differential diagnosis
Diagnostic tests
Treatment
Results
Conclusion
CHAPTER 80 Upper Thoracic Sympathectomy: Conventional Technique
Neuroanatomy of upper thoracic sympathetic chain
Indications
Operative techniques
Pitfalls and complications
CHAPTER 81 Thoracoscopic Sympathectomy
Introduction
Surgical anatomy of the sympathetic trunk
Indications
Nomenclature and surgical technique
Results
Conclusion
PART XI: Arterial-Venous Malformation, Access for Hemodialysis and Portal Hypertension
CHAPTER 82 Arteriovenous Fistulas and Vascular Malformations
Historical note
Etiology
Pathophysiology
Acquired arteriovenous fistulas
Diagnosis
Vascular malformations
Classifications
Malformations with arteriovenous shunting
Visceral arteriovenous malformations
Klippel–Trénaunay syndrome
Conclusion
CHAPTER 83 Vascular Access for Dialysis
Historical background
Prerequisites for a dialysis vascular access
Techniques for vascular access
Acute temporary vascular access
Chronic vascular access
CHAPTER 84 Portal Hypertension
Historical background
Anatomy and pathophysiology
Etiology of portal hypertension
Evaluation of patients with portal hypertension
Complications of portal hypertension
Surgical techniques
Budd–chiari syndrome
Portal hypertension in children
Devascularization and esophageal transection
Liver transplantation
CHAPTER 85 Endovascular Treatment of Portal Hypertension
Pathogenesis of portal hypertension
Transjugular intrahepatic portosystemic shunt
Balloon occluded retrograde transvenous obliteration
Endovascular management of Budd–Chiari Syndrome
Sinistral portal hypertension
Conclusion
PART XII: Venous and Lymphatic Disorders
CHAPTER 86 Clinical Application of Objective Testing in Venous Insufficiency
Essential background
Ceap classification
Diagnostic approach
Duplex assessment of venous reflux
Reflux examination development
Validation of duplex testing
Duplex determination of patterns of venous reflux
Valve incompetence in limbs with venous ulceration
Correction of deep venous reflux by superficial venous stripping
Proximal reflux affects distal deep venous function
Hemodynamic testing
Conclusion
CHAPTER 87 Varicose Veins
Introduction
Saphenectomy
Thermal ablation
Chemical ablation
Ambulatory phlebectomy and transilluminated powered phlebectomy
CHIVA
ASVAL
Compression
Recurrent varicose veins
Vulvar varices
CHAPTER 88 Superficial Thrombophlebitis
Introduction
Clinical presentation
Etiology
Pathology
Diagnosis
Treatment
CHAPTER 89 Acute Deep Vein Thrombosis and Contemporary Venous Thrombectomy
Etiology
Diagnosis
Management of acute deep venous thrombosis
Treatment strategies
Contemporary venous thrombectomy
Contemporary results
Technique of venous thrombectomy
Conclusions
CHAPTER 90 Acute Upper Extremity Deep Venous Thrombosis
Introduction
UEDVT
UEDVT versus LEDVT
Placement of superior vena cava filters
Hypercoaguable states associated with UEDVT
Combined UEDVT and LEDVT
Conclusions
CHAPTER 91 Vena Cava Filters
Venous thromboembolic disease
Historical background
General overview
Indications for mechanical protection devices
Technical placement of IVC filters
Special patient groups
Specific filters
Permanent filters
Retrievable and temporary filters
Conclusions
CHAPTER 92 Repair of Iliac and Iliocaval Venous Obstructions
Pathophysiology
Clinical features
Diagnosis
Treatment
Technique
Results
Conclusion
CHAPTER 93 Ablation of Major Incompetent Superficial Veins
Endovenous thermal ablation of the saphenous vein
Results of superficial reflux ablation
CHAPTER 94 Management of Perforator-vein Incompetence
Introduction
Current perforator therapies
CHAPTER 95 Ischemic Venous Thrombosis: Phlegmasia Cerulea Dolens and Venous Gangrene
Introduction
Historical background
Pathophysiology
Etiology
Clinical presentation
Diagnosis
Treatment
Conclusions
CHAPTER 96 Diagnosis and Management of Lymphedema
Normal lymphatics
Classification
Etiology
Diagnosis
Diagnostic methods of evaluation
Treatment
PART XIII: Amputations and Rehabilitation
CHAPTER 97 Amputation of the Lower Extremity: General Considerations
General principles
Principles of conservative management (nonsurgical)
Levels of amputation
CHAPTER 98 Major Amputations
General principles
Above-the-knee amputations
Failed grafts and level of amputation
Pitfalls of amputation
Complications of amputation
Below-knee amputations
Through-knee amputation
Advantages of below-the-knee versus above-the-knee amputations
CHAPTER 99 Postoperative and Preprosthetic Management for Lower Extremity Amputations
Hip disarticulation
Transfemoral amputation
Through-the-knee amputation
Transtibial amputation
Syme’s amputation
CHAPTER 100 Prosthetic Fitting and Management of Lower Extremity Amputees
The ideal residual limb
The prosthetic fitting process
Late-effect complications
Amputee adjustment
Acknowledgments
Index
To my son Michael Sam and my daughter Andrea Rachel for being the major source of inspiration and happiness.
Enrico Ascher, July 2012
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Library of Congress Cataloging-in-Publication Data
Haimovici’s vascular surgery. – 6th ed. / editor-in-chief, Enrico Ascher ; co-editors, Frank J. Veith, Peter Gloviczki ; associate editors, Keith D. Calligaro ... [et al.].
p. ; cm.
Vascular surgery
Includes bibliographical references and index.
ISBN 978-1-4443-3071-7 (hardcover : alk. paper)
I. Haimovici, Henry, 1907-2001. II. Ascher, Enrico. III. Title: Vascular surgery.
[DNLM: 1. Vascular Surgical Procedures. 2. Vascular Diseases–diagnosis. 3. Vascular Diseases–surgery. WG 170]
617.4'13–dc23
2011048151
A catalogue record for this book is available from the British Library.
Wiley also publishes its books in a variety of electronic formats. Some content that appears in print may not be available in electronic books.
Cover image: Courtesy of Eraxion/iStockphoto
Cover design by Steve Thompson
Preface
Henry Haimovici was one of the founding fathers of vascular surgery and it has been a privilege and an honor for me to be allowed to help edit yet another version of his book. Henry died on July 10, 2001 at the age of 93 in New York City following a brilliant clinical and academic career as a vascular surgeon. Henry was a prolific scientific researcher and a well respected surgeon-scientist who contributed in many ways for the maturation of vascular surgery. His pioneer work in the understanding of the pathophysiology and treatment of vascular diseases is impressive. One example is the recognition of renal and metabolic complications of extensive venous thrombosis of the lower extremities leading to gangrene. Henry called it “ischemic venous thrombosis” but the condition became popular under the name of phlegmasia cerula dolens. Dr. Haimovici’s leadership position among vascular surgeons worldwide led him to be one of the founders of the International Society for Cardiovascular Surgery as well as a founding co-editor of the Journal of Cardiovascular Surgery. He became president of the prestigious North American Chapter of the ISCVS (1959–1960) and in 1986 he was elected a corresponding member of the French National Academy of Medicine, an honor bestowed upon so few of the great academicians. Henry Haimovici, a mentor and friend, continues to live among us through his many important contributions to vascular surgery.
Since the last edition of Haimovici’s Vascular Surgery in 2004, endovascular surgery and management of venous diseases continued to play an increasingly important role in the daily activities of vascular surgeons. Accordingly, I was elated when both Drs. Frank J. Veith and Peter Gloviczki accepted to be the principal Co-Editors of the current edition. These legendary surgeons have added significantly to the book and I want to thank them for all their contributions. Equally, I need to recognize and thank all the Co-Editors who did an excellent job reviewing the various chapters and for writing their own chapters. Without this superb group of highly talented surgeons the 6th edition would not have come to fruition.
This edition follows the same principles originally outlined by Henry Haimovici, that is, a combination of fundamental surgical principles with well established vascular and endovascular techniques. Of the 100 chapters in this edition, 31 are totally new chapters and most others have been updated. We left most of Haimovici’s chapters unchanged since they are technical in nature and very well described. I believe the readers of this book will find these and all other chapters to be of great value.
I want to thank Dr. Anil P. Hingorani for his contributions to the book and for allowing me the time to complete this and many other projects. Anne Ober, my assistant of 16 years has been very helpful in following-up with the various authors and keeping us on schedule. Lastly, I want to thank Wiley-Blackwell for all their support and guidance during the creation of this edition.
Enrico Ascher, MDNew York, New York 2012
The editor and publishers have made every effort to contact all the copyright holders to obtain their permission to reproduce copyright material. However, if any have been inadvertently overlooked, the publisher will be pleased to make the necessary arrangements at the first opportunity.
Enrico Ascher
Preface to the Fifth Edition
It has been nearly three decades since the late Dr Henry Haimovici (1907–2001) first presented to us his landmark publication Vascular Surgery: Principles and Techniques. Even then he observed that, in this historically brief period of time, we had already experienced momentous developments in the magnitude and scope of our specialty. I believe that, unlike any other period of time and unlike any other surgical specialty, we have also maintained the ability to focus and redirect our craft in tandem with, if not in advance of, the changing needs of our patients and the technological advancements available to us. As a great pioneer of vascular surgery, Dr Haimovici was a principal instrument of our success throughout the infancy and maturation of vascular surgery. He was ever committed to its future beyond measure. Henry was also my mentor and a great friend. I am forever indebted to him for the privilege of assuming editorship of this grand textbook.
We are also saddened by the loss of yet another great leader in vascular surgery: D. Eugene Strandness, Jr., MD (1928–2002). Dr Strandness fielded numerous contributions throughout the formative years of noninvasive vascular testing and ultimately established what has now become our most effective asset in the diagnosis of vascular disease—the vascular laboratory. His early work focused on physiologic tests, but he was also responsible for the development and application of direct ultrasonic methods for vascular diagnosis. Working with engineers at the University of Washington, he combined a B-mode imaging system and a Doppler flow detector to create the first duplex scanner. These explorers of science were prolific in their contributions to our specialty through their research, publications, and societal leaderships. It is in their footsteps that the current and successive generations of vascular leaders must walk—and they have left great shoes for them to fill.
We are proud to have returning Section Editors Larry Hollier (Aortic and Peripheral Aneurysms), Eugene Strandness (Imaging Techniques), and Jonathan B. Towne (Acute Arterial Occlusions of the Lower Extremities). We are also fortunate to have joining us K. Craig Kent (Basic Cardiovascular Problems), John J. Ricotta (Cerebrovascular Insufficiency), Keith D. Calligaro (Visceral Vessels), Gregory L. Moneta (Specific Upper Extremity Occlusions), and William H. Pearce (Venous and Lymphatic Surgery) as Section Editors.
This 5th edition of Haimovici’s Vascular Surgery remains true to its heritage of the comprehensive inspection of the practice of vascular surgery. Innovations in operative technique and reflections on noninvasive diagnostic imaging have been examined and each topic has been updated and expanded. This textbook has now included the most current topics regarding endovascular therapy. Extensive changes have been made to this edition—fully 75 chapters have been revised and 25 new chapters have been added.
Enrico Ascher, MDNew York, New York2003
Contributors
Ali F. AbuRahma MDProfessor of SurgeryChief, Vascular and Endovascular SurgeryDirector, Vascular Surgery FellowshipMedical Director, Vascular LaboratoryCo-Director, Vascular Center of ExcellenceRobert C. Byrd Health Sciences CenterWest Virginia UniversityCharleston, WV, USA
Samuel S. Ahn MD, FACSClinical Professor of SurgeryUCLA School of Medicine;Attending SurgeonUCLA Center for the Health SciencesDivision of Vascular SurgeryLos Angeles, CA, USA
Jose I. Almeida MD, FACS, RVTDirector, Miami Vein CenterVoluntary Associate Professor of SurgeryUniversity of Miami—Jackson Memorial HospitalMiami Vein CenterMiami, FL, USA
Enrico Ascher MDChief of Vascular and Endovascular Surgery Lutheran Medical Center;Professor of SurgeryMount Sinai School of MedicineNew York, NY, USA
Javier E. Anaya-Ayala MDResearch Vascular FellowDepartment of Cardiovascular SurgeryMethodist DeBakey Heart and Vascular CenterHouston, TX, USA
Dennis F. Bandyk MDProfessor of SurgeryDivision of Vascular and Endovascular SurgeryUniversity of California San DiegoLa Jolla, CA, USA
Donald T. Baril MDDivision of Vascular SurgeryUniversity of Pittsburgh Medical CenterPittsburgh, PA, USA
Carlos F. Bechara MD, MSAssistant Professor of SurgeryBaylor College of MedicineHouston, TX, USA
John J. Bergan MD, FACSProfessor of SurgeryUniversity of California, San DiegoProfessor of SurgeryUniformed Services of the Health SciencesBethesda, MD, USA
Ramon Berguer MD, PhDProfessor of SurgeryUniversity of MichiganSchool of MedicineAnn Arbor, MI, USA
Todd L. Berland MD, RPVIAssistant Professors of SurgeryNew York University Medical CenterNew York, NY, USA
W. Austin Blevins MDDivision of Vascular TherapyHawaii Permanente Medical GroupKaiser Foundation HospitalHonolulu, HI, USA
Raphael Blochle MDAssistant Professor of SurgeryThe State University of New YorkBuffalo, NY, USA
John C. Bowen MDChairman Emeritus, Department of SurgeryOchsner Clinic FoundationNew Orleans, LA, USA
Colin M. Brady MDDivision of Vascular Surgery and Endovascular TherapyEmory University School of MedicineAtlanta, GA, USA
David C. Brewster MDClinical Professor of SurgeryHarvard Medical School;SurgeonMassachusetts General HospitalBoston, MA, USA
Igor Brichkov MDAttending SurgeonDivision of Thoracic SurgeryMaimonides Medical CenterBrooklyn, NY, USA
Warner P. Bundens MDAssistant Clinical Professor of SurgeryUniversity of CaliforniaSan Diego, CA, USA
John Byrne MDClinical Fellow in Vascular SurgeryAlbany Medical CenterAlbany, NY, USA
Keith D. Calligaro MDAssociate Clinical ProfessorUniversity of Pennsylvania School of Medicine;Chief, Section of Vascular SurgeryPennsylvania HospitalPhiladelphia, PA, USA
Neal S. Cayne MD, FACSAssistant Professor of SurgeryNew York University Medical CenterNew York, NY, USA
Elliot L. Chaikof MD, PhDJohnson and Johnson Professor of SurgeryHarvard Medical School;Chairman, Roberta and Stephen R. Weiner Department of Surgery;Surgeon-in-ChiefBeth Israel Deaconess Medical CenterBoston, MA, USA
Charlie C. Cheng MDAssistant Professor of SurgeryDivision of Vascular Surgery and Endovascular TherapyTexas Vascular CenterThe University of Texas Medical BranchGalveston, TX, USA
Lorraine Choi MDAssistant Professor of SurgeryDivision of Vascular Surgery and Endovascular TherapyTexas Vascular CenterThe University of Texas Medical BranchGalveston, TX, USA
G. Patrick Clagett MDChairman, Division of Vascular and Endovascular Medicine SurgeryUniversity of Texas Southwestern Medical CenterDallas, TX, USA
Anthony J. Comerota MD, FACS, FACCAdjunct Professor of SurgeryUniversity of MichiganDirector, Jobst Vascular InstituteThe Toledo HospitalToledo, OH, USA
Joseph S. Coselli MDProfessor and Chief of the Division of Cardiothoracic SurgeryMichael E. DeBakey Department of SurgeryBaylor College of Medicine;Chief of the Section of Adult Cardiac SurgeryThe Texas Heart Institute at St. Luke’s Episcopal HospitalHouston, TX, USA
Enrique Criado MDProfessor of SurgeryUniversity of Michigan School of MedicineAnn Arbor, MI, USA
Jacob Cynamon MDClinical Professor of RadiologyAlbert Einstein College of Medicine;Director, Division of Vascular and Interventional RadiologyMontefiore Medical CenterBronx, NY, USA
Alan Dardik MD, PhDAssociate Professor of SurgeryDepartment of SurgeryThe Yale University School of MedicineNew Haven, CT, USA
R. Clement Darling III MDProfessor of SurgeryAlbany Medical College;Chief, Division of Vascular SurgeryAlbany Medical CenterAlbany, NY, USA
Mark G. Davies MD, PhD, MBAProfessor of SurgeryWeill Medical College at Cornell UniversityNew York, NY;Department of Cardiovascular SurgeryMethodist DeBakey Heart and Vascular CenterHouston, TX, USA
Brian G. DeRubertis MDAssistant Professor of Surgery David Geffen School of Medicine at UCLALos Angeles, CA, USA
Matthew J. Dougherty MD, FACSAssistant Clinical ProfessorUniversity of PennsylvaniaSection of Vascular SurgeryPennsylvania HospitalPhiladelphia, PA, USA
Jonathan L. Eliason MDAssistant Professor of SurgerySection of Vascular SurgeryUniversity of MichiganAnn Arbor, MI, USA
Calvin B. Ernst MDClinical Professor of SurgeryUniversity of Michigan Medical School;Head, Division of Vascular SurgeryHenry Ford HospitalDetroit, MI, USA
Anthony L. Estrera MDChief of Cardiac SurgeryDepartment of Cardiothoracic and Vascular SurgeryThe University of Texas at Houston Medical SchoolMemorial Hermann Heart and Vascular InstituteHouston, TX, USA
Alik Farber MDChief of Vascular and Endovascular SurgeryBoston Medical Center;Associate Professor of Surgery and RadiologyBoston University School of MedicineBoston, MA, USA
April Farley BSBaylor College of MedicineHouston, TX, USA
Peter L. Faries MD, FACSDivision Chief, Vascular SurgeryProfessor of SurgeryProfessor of RadiologyMount Sinai Medical CenterNew York, NY, USA
Javairiah Fatima MB, BSResident, Department of SurgeryMayo ClinicRochester, MN, USA
Julie A. Freischlag MDThe William Stewart Halsted Professor of SurgeryChair, Department of SurgerySurgeon-in-Chief, Department of SurgeryJohns Hopkins Medical InstitutionsBaltimore, MD, USA
Karan Garg MDSurgery ResidentNew York University Medical CenterNew York, NY, USA
Nicholas J. Gargiulo III MDUniversity of RochesterRochester, NY, USA
Ramyar Gilani MDMichael E. DeBakey Department of SurgeryBaylor College of MedicineHouston, TX, USA
Natalia O. Glebova MD, PhDResident in General SurgeryJohns Hopkins HospitalBaltimore, MD, USA
Peter Gloviczki MDProfessor of SurgeryMayo Medical School;Chair, Division of Vascular SurgeryDirector, Gonda Vascular CenterMayo Clinic and FoundationRochester, MN, USA
Yosef Golowa MDClinical Assistant Professor of RadiologyAlbert Einstein College of Medicine;Attending Radiologist, Division of Vascular and Interventional RadiologyMontefiore Medical CenterBronx, NY, USA
Kapil Gopal MD, MBAAssistant Professor of SurgeryUniversity of Maryland School of MedicineBaltimore, MD, USA
Henry Haimovici MD(deceased)Former Foreign Corresponding MemberFrench National Academy of MedicineParis, FranceFormer Clinical Professor Emeritus of SurgeryAlbert Einstein College of Medicine at Yeshiva UniversityFormer Senior Consultant andChief Emeritus of Vascular SurgeryMontefiore Medical CenterBrooklyn NY, USA
Linda M. Harris MD, FACSAssociate Professor of SurgeryThe State University of New YorkBuffalo, NY, USA
Foster A. Hays BSUniversity of Texas Southwestern Medical CenterDallas, TX, USA
Asher Hirshberg MDProfessor of SurgeryState University of New YorkDownstate College of Medicine;Director of Vascular SurgeryKings County Hospital CenterBrooklyn, NY, USA
Anil Hingorani MDAttending SurgeonLutheran Medical Center;Associate ChairmanThe Vascular Institute of New York;Associate Professor of SurgeryMount Sinai School of MedicineNew York, NY, USA
Jeffrey Hnath MDAlbany Medical College / Albany Medical Center HospitalThe Institute for Vascular Health and DiseaseAlbany, NY, USA
Kim J. Hodgson MDProfessor and ChairDivision of Vascular SurgerySouthern Illinois UniversitySchool of MedicineSpringfield, IL, USA
Frederick L. Hoff MDAssistant Professor of RadiologyDepartment of RadiologyNorthwestern University Medical SchoolChicago, IL, USA
Douglas B. Hood MDAssociate ProfessorDivision of Vascular SurgerySouthern Illinois UniversitySchool of MedicineSpringfield, IL, USA
Joel H. Horovitz MD, FACS, FRCS(C)Vice Chairman, Department of SurgeryDirector, General SurgeryMaimonides Medical CenterBrooklyn, NY, USA
Larry H. Hollier MD, FACS, FACC, FRCS (Eng)Chancellor of Louisiana State UniversityHealth Sciences CenterNew Orleans, LA, USA
Carber C. Huang MDEndovascular Fellow, Division of Vascular SurgeryUCLA School of MedicineLos Angeles, CA, USA
Joseph Huh MDAssociate Professor, Division of Cardiothoracic SurgeryMichael E. DeBakey Department of SurgeryBaylor College of Medicineand Cardiovascular Surgery StaffThe Texas Heart Institute at St. Luke’s Episcopal HospitalHouston, TX, USA
Mark Iafrati MDChief, Vascular SurgeryDirector Vascular Medicine CenterTufts Medical CenterBoston, MA, USA
Juan Carlos Jimenez MD, FACSAssistant Professor of SurgeryGonda (Goldschmied) Vascular CenterDavid Geffen School of Medicine at UCLA;Attending SurgeonRonald Reagan UCLA Medical CenterUCLA-Olive View Medical CenterUCLA-Santa Monica HospitalLos Angeles, CA, USA
Gustavo De Jesús-Gómez MDDivision of Vascular and Endovascular Surgery,University of South Florida College of MedicineTampa, FL, USA
Jeanwan Kang MDVascular Surgery FellowMassachusetts General HospitalDivision of Vascular and Endovascular SurgeryBoston, MA, USA
Manju Kalra MBBSAssociate Professor of Surgeryand Consultant, Division of Vascular and Endovascular SurgeryMayo ClinicRochester, MN, USA
Aoife N. Keeling FFR RCSIInterventional RadiologyNorthwestern University Medical SchoolChicago, IL, USA
K. Craig Kent MDProfessor of SurgeryColumbia Weill Cornell Division of Vascular SurgeryColumbia College of Physicians and SurgeonsWeill Medical College of Cornell UniversityNew York, NY, USA
George Kopchok BSBiomedical EngineerLos Angeles Biomedical Research Institute atHarbor UCLA Medical CenterTorrance, CA, USA
Christopher J. Kwolek MDProgram Director in Vascular SurgeryMassachusetts General HospitalDivision of Vascular and Endovascular SurgeryBoston, MA, USA
Gregory J. Landry MDAssociate Professor of SurgeryDivision of Vascular SurgeryOregon Health and Science UniversityPortland, OR, USA
Peter F. Lawrence MDDirector, Gonda (Goldschmied) Vascular CenterWiley Barker Endowed Chair and Chief of Vascular Surgery David Geffen School of Medicine at UCLALos Angeles, CA, USA
Scott A. LeMaire MDProfessor and Director of ResearchDivision of Cardiothoracic SurgeryMichael E. DeBakey Department of SurgeryBaylor College of Medicineand Cardiovascular Surgery StaffThe Texas Heart Institute at St. Luke’s Episcopal HospitalHouston, TX, USA
Peter H. Lin MDProfessor of SurgeryBaylor College of MedicineHouston, TX, USA
Evan C. Lipsitz MDAssociate Professor of SurgeryChief, Division of Vascular and Endovascular SurgeryMontefiore Medical Center and the Albert Einstein College of MedicineBronx, NY, USA
Bo Liu PhDAssociate ProfessorDepartment of SurgerySchool of Medicine and Public HealthUniversity of WisconsinMadison, WI, USA
Alan B. Lumsden MDProfessor of SurgeryWeill Medical College at Cornell UniversityNew York, NY;Chairman, Department of Cardiovascular SurgeryMedical DirectorMethodist DeBakey Heart and Vascular CenterHouston, TX, USA
Harry Ma MD, PhDVascular SurgeryTufts Medical CenterBoston, MA, USA
Robyn A. Macsata MD, FACSChief, Vascular SurgeryVeterans Affairs Medical CenterWashington DC, USA
Michel S. Makaroun MDDivision of Vascular SurgeryUniversity of Pittsburgh Medical CenterPittsburgh, PA, USA
Jesse M. Manunga, Jr. MDFellow, Division of Vascular and Endovascular SurgeryMayo ClinicRochester, MN, USA
Natalie Marks MD, RVTThe Vascular Institute of New YorkDivision of Vascular Surgery at Maimonides Medical CenterBrooklyn, NY, USA
Kenneth L. Mattox MDDistinguished Service ProfessorMichael E. DeBakey Department of SurgeryBaylor College of MedicineHouston, TX, USA
Manish Mehta MD, MPHAssociate Professor of SurgeryAlbany Medical College / Albany Medical Center HospitalThe Institute for Vascular Health and DiseaseAlbany, NY, USA
Charles C. Miller IIIFoster School of MedicineTexas Tech University Health Sciences CenterEl Paso, TX, USA
Yoshio Mishima MDProfessor and Chairman of SurgeryTokyo Medical and Dental UniversityTokyo, Japan
Lynn S. Model MDDepartment of SurgeryThe Yale University School of MedicineNew Haven, CT, USA
Takki A. Momin MDVascular Surgery FellowGeorgetown University / Washington Hospital CenterWashington DC, USA
Gregory L. Moneta MDProfessor of SurgeryChief, Division of Vascular SurgeryOregon Health Sciences UniversityPortland, OR, USA
Albeir Y. Mousa MDAssistant ProfessorDepartment of SurgeryRobert C. Byrd Health Sciences CenterWest Virginia UniversityCharleston, WV, USA
Peter A. Naughton MDFellow, Vascular SurgeryNorthwestern University Medical SchoolChicago, IL, USA
Peter Neglen MD, PhDUniversity of Mississippi Medical Centerand River Oaks HospitalFlowood, MS, USA
Nicolas Nelken MDDivision of Vascular TherapyHawaii Permanente Medical GroupKaiser Foundation HospitalHonolulu, HI, USA
Richard F. Neville MD, FACSChief, Division of Vascular SurgeryProfessor of SurgeryGeorge Washington UniversityWashington, DC, USA
Audra A. Noel MDAssistant Professor of SurgeryMayo Medical SchoolConsultantDivision of Vascular SurgeryMayo ClinicRochester, MN, USA
Gustavo S. Oderich MDAssociate Professor of SurgeryConsultant, Saint Marys and Methodist HospitalDirector of Endovascular TherapyDirector of Edward Rogers Clinical Research Fellowship ProgramDivision of Vascular and Endovascular SurgeryMayo Clinic College of MedicineRochester, MN, USA
Kenneth Ouriel MDSyntactxNew York, NY, USA
William H. Pearce MDViolet R. and Charles A. Baldwin Professor of Vascular SurgeryDepartment of SurgeryNorthwestern University Medical SchoolChicago, IL, USA
Eric K. Peden MDAssistant Professor of SurgeryWeill Medical College at Cornell UniversityNew York, NY;Department of Cardiovascular SurgeryMethodist DeBakey Heart and Vascular CenterHouston, TX, USA
Bruce A. Perler MD, MBAJulius H Jacobson, II Professor of SurgeryChief, Division of Vascular Surgery & Endovascular TherapyJohn Hopkins UniversitySchool of MedicineBaltimore, MD, USA
Adam H. Power MDClinical Fellow in Vascular and Endovascular SurgeryDivision of Vascular and Endovascular SurgeryMayo Clinic College of MedicineMayo ClinicRochester, MN, USA
William J. Quinones-Baldrich MDProfessor of SurgeryDavid Geffen School of Medicine at UCLA;Director UCLA Aortic CenterRonald Reagan UCLA Medical CenterLos Angeles, CA, USA
Rodeen Rahbar MD, FACSAssistant Professor of SurgeryGeorge Washington UniversityWashington, DC, USA
Jeffrey K. Raines PhD, RVTDirector, Vascular Laboratory and ResearchMiami Vein CenterEmeritus Professor of SurgeryUniversity of Miami Miller School of MedicineMiami, FL, USA
Seshadri Raju MDProfessor Emeritus and Honorary SurgeonUniversity of MS Medical Center;Attending PhysicanRiveroaks HospitalFlowood, MS, USA
Jorge Rey MDThe Institute for Vascular Health and DiseaseAlbany Medical College / Albany Medical Center HospitalAlbany, NY, USA
John J. Ricotta MDChairman of SurgeryWashington Hospital Center and Georgetown UniversityWashington, DC, USA
Joseph J. Ricotta II MD, MSAssistant Professor of SurgeryDirector of Clinical ResearchDirector, International Clinical Research Fellowship in Vascular SurgeryAssociate Program Director, Vascular Surgery FellowshipDivision of Vascular Surgery and Endovascular TherapyEmory University School of MedicineAtlanta, GA, USA
David A. Rigberg, MDAssociate Professor of SurgeryDavid Geffen School of Medicine at UCLALos Angeles, CA, USA
Sean P. Roddy MDAssociate Professor of SurgeryThe Institute for Vascular Health and DiseaseAlbany Medical CollegeAlbany Medical Center HospitalAlbany, NY, USA
Hazim J. SafiDepartment of Cardiothoracic and Vascular SurgeryThe University of Texas at Houston Medical SchoolMemorial Hermann Heart and Vascular InstituteHouston, TX, USA
Russell H. Samson MD, RVT, FACSClinical Associate Professor of Surgery (Vascular) and President, Mote Foundation IncFlorida State University Medical SchoolTallahassee, FL, USA
Richard J. Sanders MDClinical Professor of SurgeryUniversity of Colorado School of MedicineRose Medical CenterDenver, CO, USA
Sartaj S. Sanghera MDSurgical Oncology FellowRoswell Park Cancer InstituteBuffalo, NY, USA
Andres Schanzer MDAssociate Professor of SurgeryUniversity of Massachusetts Medical SchoolDivision of Vascular and Endovascular SurgeryWorcester, MA, USA
Harry Schanzer MD, FACSClinical Professor of SurgeryMount Sinai School of Medicine;Attending SurgeonMount Sinai HospitalNew York, USA
Peter A. Schneider MDDivision of Vascular TherapyHawaii Permanente Medical GroupKaiser Foundation HospitalHonolulu, HI, USA
Gary R. Seabrook MDProfessor of Vascular SurgeryMedical College of WisconsinMilwaukee, WI, USA
Amit R. Shah MDVascular SurgeonMontefiore Medical Center and the Albert Einstein College of MedicineBronx, NY, USA
Tejas R. Shah MDDepartment of SurgeryMount Sinai Medical CenterNew York, NY, USA
Jason P. Shaw MDAttending SurgeonDivision of Thoracic SurgeryMaimonides Medical CenterBrooklyn, NY, USA
Roy SheinbaumDepartment of Cardiothoracic and Vascular SurgeryThe University of Texas at Houston Medical SchoolMemorial Hermann Heart and Vascular InstituteHouston, TX, USA
Alexander Shiferson DODepartment of Vascular SurgeryMaimonides Medical CenterBrooklyn, NY, USA
Anton N. Sidawy MD, MPH, FACSProfessor and ChairmanDepartment of SurgeryGeorge Washington UniversityWashington, DC, USA
Michael B. Silva Jr MDThe Fred J. and Dorothy E. Wolma Professor in VascularSurgery and Professor of RadiologyChief, Division of Vascular Surgery and Endovascular TherapyDirector, Texas Vascular CenterThe University of Texas Medical BranchGalveston, TX, USA
Taylor A. Smith MDDivision of Vascular and Endovascular Surgery Ochsner Medical CenterNew Orleans, LA, USA
James C. Stanley MDHandleman Professor of SurgerySection of Vascular SurgeryUniversity of MichiganAnn Arbor, MI, USA
Yaron Sternbach MDAssociate Professor of SurgeryAlbany Medical College / Albany Medical Center HospitalThe Institute for Vascular Health and DiseaseAlbany, NY, USA
Jan J. Stokosa CP, FAAOPAmerican Prosthetic InstituteStokosa Prosthetic ClinicEast Lansing, MI, USA
David S. Sumner MDDistinguished Professor of SurgeryChief, Section of Peripheral Vascular SurgerySouthern Illinois University School of MedicineSpringfield, IL, USA
Bauer E. Sumpio MD, PhDProfessor and Vice Chairman of SurgeryChief, Vascular SurgeryYale University School of Medicine;Chief, Vascular ServiceYale–New Haven HospitalNew Haven, CT, USA
John B. Taggert MDAlbany Medical College / Albany Medical Center HospitalThe Institute for Vascular Health and DiseaseAlbany, NY, USA
Martin D. Tilson MDAilsa Mellon Bruce Professor of Surgery Columbia University;Director EmeritusDepartment of SurgerySt. Luke’s / Roosevelt HospitalNew York, NY, USA
William D. Turnipseed MDProfessor of SurgeryDivision of Vascular SurgeryUniversity of Wisconsin HospitalMadison, WI, USA
Frank J. Veith MD, FACSDivision of Vascular SurgeryNew York University Medical CenterNew York, NY;The Cleveland ClinicCleveland, OH, USA
Rodney A. White MDChief of Vascular SurgeryHarbor–UCLA Medical Center, Torrance, CA;Professor of Surgery, UCLA School of MedicineLos Angeles, CA, USA
Tze-Woei Tan MDFellow, Vascular SurgeryBoston Medical CenterBoston, MA, USA
Yeongchi Wu MDAssociate Professor of Physical Medicine and RehabilitationNorthwestern University Medical School;Director, Amputee RehabilitationRehabilitation Institute of ChicagoCenter for International RehabilitationChicago, IL, USA
List of Abbreviations
AAA
abdominal aortic aneurysm
AAAP-40
aortic aneurysm-associated protein 40
AASV
anterior accessory saphenous vein
ABF
aortofemoral bypass
ABI
ankle-brachial index
ABPI
ankle brachial pressure index
ACE
angiotensin-converting enzyme
ACP
antegrade cerebral perfusion
ACS
acute coronary syndromes
ACT
activated clotting time
ADP
adenosine diphosphate
AER
abduction external rotation
AIOD
aortoiliac occlusive disease
ALI
acute limb ischemia
AMI
acute mesenteric ischemia
AMP
adenosine monophosphate
AMS
absorbable metal stent
ANA
antinuclear antibody
AP
ambulatory phlebectomy
APC
activated protein C
APG
air plethysmography
ApoA
apoprotein A
ApoB
apoprotein B
aPTT
activated partial thromboplastin time
ARB
angiotensin-receptor blocking agent
ASM
anterior scalene muscle
ASO
arteriosclerosis obliterans
ASVAL
ambulatory selective varices ablation under local anesthesia
ATIII
antithrombin III
ATOS
arterial thoracic outlet syndrome
ATP
adenosine triphosphate
AV
arteriovenous
AVA
arteriovenous anastomosis
AVF
arteriovenous fistula
AVG
arteriovenous grafts
AVM
arteriovenous malformation
AVSS
Aberdeen varicose vein severity score
BAI
blunt aortic injury
BAM
balloon-assisted maturation
BCS
Budd–Chiari syndrome
BCVI
blunt cerebrovascular injury
bFGF
basic fibroblast growth factor
BIPAP
bi-level positive airway pressure
BMAC
bone marrow aspirate concentrate
BMS
bare-metal stent
BP
blood pressure
BPA
blood-pool contrast agents
BRTO
balloon-occluded retrograde transvenous obliteration
CA
carotid artery, contrast angiography
CAA
carotid artery atherosclerosis, celiac artery aneurysm
CABG
coronary artery bypass graft
CACS
celiac artery compression syndrome
CAD
coronary artery disease
cAMP
cyclic adenosine monophosphate
CAS
carotid artery stenting
CBA
cutting-balloon angioplasty
CBP
cardiopulmonary bypass
CCA
common carotid artery
CCS
chronic compartment syndrome
CEA
carotid endarterectomy
CFA
common femoral artery
CFDI
color flow duplex imaging
cGFR
calculated glomerular filtration rate
cGMP
cyclic guanine monophosphate
CGRP
calcitonin gene-related peptide
CHD
coronary heart disease
CHF
congestive heart failure
CIA
common iliac artery
CIN
contrast-induced nephropathy
CLI
critical limb ischemia
CMI
chronic mesenteric ischemia
COPD
chronic obstructive pulmonary disease
CPAP
continuous positive airway pressure
CPB
cardiopulmonary bypass
CRI
chronic renal insufficiency
CRP
C-reactive protein
CRPS
complex regional pain syndrome
CSF
cerebrospinal fluid
CT
computed tomography
CTA
computed tomographic angiography
CTO
chronic total occlusion
CV
contrast venography
CVD
cardiovascular disease, chronic venous disease
CVI
chronic venous insufficiency
DA
duplex arteriography
DAG
diacylglycerol
dAVF
distal arteriovenous fistula
DES
drug-eluting stent
DHCA
deep hypothermic circulatory arrest
DLT
decongestive lymphatic therapy
DR
diameter reduction
DSA
digital subtraction angiography
DSE
dobutamine stress echocardiography
DSRS
distal splenorenal shunt
DTPA
diethylenetriamine pentaacetic acid
DUS
duplex ultrasound
DVP
distal vein patch
DVT
deep vein thrombosis
DWI
diffusion-weighted imaging
DW-MR
diffusion-weighted magnetic resonance
EAST
elevated arm stress test
EC
endothelial cell
ECA
external carotid artery
ECG
electrocardiogram
ECM
extracellular matrix
EDRF
endothelial-dependent relaxing factor
EDS
Ehlers–Danlos syndrome
EDV
end-diastolic velocity
EEG
electroencephalogram
EEL
external elastic lamina
EGF
epidermal growth factor
EHIT
endovenous heat-induced thrombosis
EIA
external iliac artery
ELG
endoluminal graft
ELISA
enzyme-linked immunosorbent assay
eNOS
endothelial nitric oxide synthase
EPC
endothelial progenitor cell
EPD
embolic protection devices
EPSF
early postsurgical fitting
ePTFE
expanded polytetrafluoroethylene
ER-DP
extended-release dipyridamole
E-selectin
endothelial-cell selectin
ESR
erythrocyte sedimentation rate
ESRD
end-stage renal disease
ET
endothelin
EVAR
endovascular aneurysm repair
EVL
endovenous laser
EVPAR
endovascular popliteal artery aneurysm repair
FAP
femoral artery pressure
FAK
focal adhesion kinase
FDA
Food and Drug Administration
FEP
fluorinated ethylene propylene
FEV1
forced expiratory volume in one second
FGF
fibroblast growth factor
FOV
field of view
FXII
factor XII
G-6PD
glucose-6-phosphate dehydrogenase
GA
general anesthesia
G-CSF
granulocyte colony-stimulating factor
GDAA
gastroduodenal aneurysm
GFR
glomerular filtration rate
GFV
graft flow velocity
GRE
gradient echo
GSM
grayscale medium
GSV
great saphenous vein
HAA
hepatic artery aneurysm
HB-EGF
heparin-binding epidermal growth factor
HBOT
hyperbaric oxygen therapy
HCC
hepatocellular carcinoma
HCI
hypobaric compression interface
HDL
high-density lipoprotein
HGF
hepatocyte growth factor
HIF
hypoxia-inducible factor
HIS
hypobaric cushion interface with integrated suspension
HIT
heparin-induced thrombocytopenia
HLA
human leukocyte antigen
HMVEC
human microvascular endothelial cell
HMWK
high-molecular-weight kininogen
HO
heme oxygenase
HRE
hypoxia response element
HRS
hepatorenal syndrome
HSC
hematopoietic stem cell
HSLW
hemoglobin-specific laser wavelengths
HU
Hounsfield unit
HUVEC
human umbilical-vein endothelial cell
IAA
iliac artery aneurysm
IBD
iliac branched device
ICA
internal carotid artery
ICAM
intercellular cell-adhesion molecule
IDE
investigational device exemption
IDL
intermediate-density lipoprotein
IEL
internal elastic lamina
IEUS
intraoperative epiaortic ultrasound
IFN
interferon
IGF
insulin-related growth factor
IH
intimal hyperplasia
IIA
internal iliac artery
IL-1
interleukin 1
IMA
inferior mesenteric artery
iNOS
inducible nitric oxide synthase
INR
international normalized ratio
IP
3
inositol triphosphate
IPG
intraoperative pressure gradient
IPSF
immediate postsurgical fitting
IPV
incompetent perforator veins
IVT
ischemic venous thrombosis
IVUS
intravascular ultrasound
KTS
Klippel–Trénaunay syndrome
LAO
left anterior oblique
LDL
low-density lipoprotein
LDL-C
low-density lipoprotein cholesterol
LE
lupus erythematosus
LE DVT
lower-extremity deep vein thrombosis
LEED
linear endovenous energy density
LHB
left heart bypass
LIMA
left internal mammary artery
LL
laparoscopic lysis
LMWH
low-molecular-weight heparin
LR
lactated Ringer’s
LSV
long saphenous vein
MACE
major adverse cardiac events
MALS
median arcuate ligament syndrome
MAP kinase
mitogen-activated protein kinase
MCA
middle cerebral artery
MCP-1
monocyte chemoattractant protein 1
MDCTA
multidetector computed tomographic angiography
MEP
motor-evoked potential
MET
metabolic equivalent
MHC
major histocompatability complex
MI
myocardial infarction
MIP
maximal intensity projection
MMP
matrix metalloproteinase
MPA
mycophenoleic acid
MR
magnetic resonance
MRA
magnetic resonance angiography
MRI
magnetic resonance imaging
MRV
magnetic resonance venography
MSC
mesenchymal stem cell
MSM
middle scalene muscle
MVT
mesenteric venous thrombosis
NIH
neointimal hyperplasia
NIV
noninvasive ventilation
NIVL
nonthrombotic iliac vein lesion
NO
nitric oxide
NOS
nitric oxide synthase
NP
naturetic peptide
NPMS
neurogenic pectoralis minor syndrome
NRH
nodular regenerative hyperplasia
NSF
nephrogenic systemic fibrosis
NTOS
neurogenic thoracic outlet syndrome
OLT
orthotopic liver transplantation
PA
popliteal artery
PAA
popliteal artery aneurysm
PAAA
para-anastomotic aortic aneurysm
PACU
post-anesthesia care unit
PAD
peripheral arterial disease
PAF
platelet-activating factor
PAI-1
plasminogen activator inhibitor 1
PAI-2
plasminogen activator inhibitor 2
PAPs
percutaneous ablation of perforators
PC
primary closure
PCA
patient-controlled anesthesia
PCD
phlegmasia cerulea dolens
PCI
percutaneous cardiac intervention
Pco2
partial pressure of carbon dioxide
PDAA
pancreaticoduodenal aneurysm
PDE5
phosphodiesterase type 5
PDGF
platelet-derived growth factor
PE
pulmonary embolism
PEEP
positive end-expiratory pressure
PEG
polyethylene glycol
PGI
2
prostacyclin
PHG
portal hypertensive gastropathy
PICA
posterior inferior cerebellar artery
PM
pectoralis minor
PMM
pectoralis minor muscle
PMS
pectoralis minor syndrome
PMT
pectoralis minor tenotomy, percutaneous mechanical thrombectomy
POBA
plain old balloon angioplasty
PPAR
peroxisome proliferator-activated receptor
PPC
postoperative pulmonary complications
PPG
photoplethysmography
PRF
pulse-repetition frequency
PSGL-1
P-selectin glycoprotein ligand 1
PSS
Paget–Schroetter syndrome
PSV
peak systolic velocity
PTA
percutaneous transluminal angioplasty
PTCV
posterior thigh circumflex vein
PTFE
polytetrafluoroethylene
PTPS
posttraumatic pain syndrome
PV
perforator vein
PVR
pulse-volume recording
QSART
quantitative sudomotor axon reflex test
QST
quantitative sensory testing
RA
renal artery, regional anesthesia
rAAA
ruptured abdominal aortic aneurysm
RAFT
radial artery flow-through
RAR
renal aortic ratio
RCP
retrograde cerebral perfusion
RCT
randomized controlled trial
RFA
radiofrequency ablation
RI
resistive index
RIMA
right internal mammary artery
RP
retroperitoneal
RRD
removable rigid dressing
RSD
reflex sympathetic dystrophy
RSRI
renal systemic renin index
rtPA
recombinant tissue plasminogen activator
RV
renal vein, residual volume
RVRR
renal vein renin ratio
RVT
registered vascular technologist
RVU
relative value units
SA
subclavian artery
SAA
splenic artery aneurysm
SCF
stem cell factor
SCI
spinal cord injury
SCM
sternocleidomastoid
SDF
stroma-derived factor
SEPS
subfascial endoscopic perforator surgery
SFA
superficial femoral artery
SFJ
saphenofemoral junction
SFJT
saphenofemoral junction thrombophlebitis
SIA
subintimal angioplasty
SIP
sympathetically independent pain
SMA
superior mesenteric artery
SMAA
superior mesenteric artery aneurysm
SMC
smooth muscle cell
SMP
sympathetically maintained pain
SNR
signal-to-noise ratio
SSEP
somatosensory-evoked potential
SSFP
steady-state free precession
SSV
short saphenous vein
SSVT
suppurative superficial venous thrombophlebitis
SVC
superior vena cava
SVC-GF
superior vena cava Greenfield filter
SVR
superficial venous reflux
SVT
superficial venous thrombophlebitis
TAA
thoracic aortic aneurysm
TAAA
thoracoabdominal aortic aneurysm
TAO
thromboangiitis obliterans
TASC
TransAtlantic Intersociety Consensus
TBPI
toe brachial pressure index
TCD
transcranial Doppler
TcPo2
transcutaneous oxygen tension
TE
echo time
TEA
transaortic endarterectomy
TEE
transesophageal echocardiography
TEVAR
thoracic endovascular aneurysm repair
TF
tissue factor
TGF
transforming growth factor
TIA
transient ischemic attack
TIMP
tissue inhibitor of metalloproteinases
TIPS
transjugular intrahepatic portosystemic shunt
TMJ
temporomandibular joint
TNF-α
tumor necrosis factor alpha
TOS
thoracic outlet syndrome
TP
transperitoneal
tPA
tissue plasminogen activator
TR
repetition time
TRAK
time-resolved angiography using keyhole
TREATS
time-resolved echo-shared angiography technique
TRICKS
time-resolved imaging of contrast kinetics
TriVex
transilluminated powered phlebectomy
TVS
temporary vascular shunts
UE DVT
upper-extremity deep vein thrombosis
UFH
unfractionated heparin
UGFS
ultrasound-guided foam scleropathy
UGS
ultrasound-guided sclerotherapy
UK
urokinase
ULTT
upper limb tension test
uPA
urokinase plasminogen activator
US
ultrasound
VAA
visceral artery aneurysm
VAS
visual analogue scale
VBI
vertebrobasilar ischemia
VCAM
vascular cell-adhesion molecule
VEGF
vascular endothelial growth factor
VH
virtual histology
VI
vascular innovation
VLA-4
very-late forming antigen 4
VLDL
very-low-density lipoprotein
VM
vascular malformation
VOD
veno-occlusive disease
V/Q
ventilation perfusion
VTE
venous thromboembolic disease
VTOS
venous thoracic outlet syndrome
WBC
white blood cell
WHVP
wedged hepatic vein pressure
WSLW
water-specific laser wavelengths
XRT
radiation therapy
PART I
Vascular Imaging Techniques and Physiologic Testing
CHAPTER 1
Arterial and Venous Duplex Scanning
Gregory L. Moneta
Oregon Health and Science University, Portland, OR, USA
The noninvasive vascular laboratory provides the scientific basis for vascular surgery. It safely provides accurate and quantitative evidence of the presence and physiologic significance of arterial and venous disease. In the modern vascular laboratory ultrasound-based techniques, particularly duplex ultrasound techniques, are most extensively employed.
Duplex ultrasound was introduced in 1974 with application to the carotid artery. “Duplex” indicates the technique combines B-mode imaging and Doppler analysis of blood-flow direction and velocity. It is extensively utilized for evaluation of carotid arteries, intra-abdominal arteries and veins, and upper- and lower-extremity arteries and veins. Since its inception, engineering and software advances have been extensive and include: 1) improved gray-scale B-mode imaging, 2) low-frequency scan heads permitting deep penetration of the ultrasound beam from the skin surface, 3) improvements in online computer-based microprocessing, and 4) addition of color-flow imaging.
Color flow is a superimposed real-time colorized image of blood flow onto a standard gray-scale B-mode picture. Echoes from stationary tissues generate B-mode images, whereas those interacting with moving substances (blood) generate a phase shift that is processed separately and color coded to give information on the direction and velocity of blood flow that reflects the magnitude and direction of the Doppler shift. Color flow dramatically reduces the time required to perform duplex examinations by allowing more rapid identification of vessels to be examined. It appears essential for duplex examination of some vessels, such as tibial arteries and veins. Color flow and the ability of modern duplex scanners to detect blood flow velocities <5 cm/s make duplex scanning practical in virtually all areas of the body.
A vibrating source produces an ultrasonic wave. In duplex ultrasound the vibrating source is the transducer. Ultrasound transducers are contained within scan heads. Scan heads steer and focus the sound beam produced by the transducer. The ultrasound image is derived from the returning echoes and is dependent on precise steering and focusing of the sound beam.
Transducers convert electrical into vibrational energy to produce the ultrasound wave. Transducers can also convert vibrational energy of returning echoes into electrical signals for analysis by the duplex machine’s software. The frequency of the vibration is determined by the design of the transducer and determines the wavelength of the sound wave. Frequency and wavelength are related, λ = c/f, where λ is the wavelength, c is the speed of sound in tissue, and f is the frequency.
Speed of sound in soft tissues averages 1540 m/s. There is little variation in the soft tissues insonated in clinical use of duplex ultrasound. Wavelength is the principle determinant of how well an ultrasound beam penetrates tissue, and wavelength depends on the frequency of the transducer. The transducer frequency is determined by the design of the transducer and is thus controlled by the manufacturer. For examination of the carotid artery, transducer frequencies of 5 to 7.5 MHz provide optimal tissue penetration for clinical purposes.
As noted above, duplex refers to the combination of Doppler and B-mode (“B” stands for “brightness”) ultrasound in the same device. Both require analysis of reflected echoes of the original sound beam created by the ultrasound transducer. B-mode analyzes the strength (intensity) and origin of the reflected echo. Doppler analyzes shifts in frequency of the original sound wave produced by the transducer.
As a sound wave passes through tissue and moves away from the transducer its strength depends upon how much the beam is scattered, attenuated, and reflected. Strength of reflected echoes depend, in part, upon differences in acoustic impedance between media. When there are major differences in acoustic impedance a large proportion of the sound beam is reflected back to the transducer. Small differences in acoustic impedances result in little reflection and the beam continues to propagate through the tissue.
