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The first book developed specifically for hospitalists managingthe growing number of patients with cardiovascular disorders Cardiovascular disease is a major cause of hospitalization andmortality worldwide, and will account for approximately twentymillion deaths in 2015. Due to this growing problem, many patientsare being managed by non-cardiovascular physicians in the inpatientsetting. As a result, hospitalists and other inpatient physicianswithout specialized training in cardiology are faced withuncertainty when contemplating the proper management of thesepatients. This book focuses on inpatient cardiovascular medicine in ahighly algorithmic and evidence-based approach, so that users willbe able to care for their hospitalized patients directly, using thebest contemporary evidence available. It emphasizes the practical,immediate application of principles and treatment recommendationsinto everyday clinical inpatient practice, while simplifying theapproach to these patients by utilizing visual aids such ascarefully designed charts, illustrations, and diagrams. Inpatient Cardiovascular Medicine features thoughtful,comprehensive coverage by top experts in the field. Topicsinclude: * Cardiovascular History and Physical Examination * Introduction to Electrocardiography * Non-invasive Cardiac Imaging * Cardiac Stress Testing and the Evaluation of Chest Pain * Perioperative Cardiac Evaluation * Cardiac Resuscitation * Acute Coronary Syndromes: Unstable Angina and Non-ST ElevationMyocardial Infarction * Acute ST-Elevation Myocardial Infarction * Chronic Coronary Artery Disease * Peripheral Arterial Disease * Thoracic Aortic Disease * Systolic Heart Failure * Diastolic Heart Failure * Dilated and Restrictive Cardiomyopathy * Hypertrophic Cardiomyopathy * Heart Transplantation and Left Ventricular Assist Devices * Syncope * Approach to the Patient with a Narrow Complex Tachycardia * Approach to the Patient with a Wide Complex Tachycardia * Atrial Fibrillation and Atrial Flutter * Antiarrhythmic Drug Therapy * Cardiac Pacemakers and Implantable Defibrillators * Valvular Heart Disease * Infective Endocarditis * Pericardial Diseases * Pulmonary Hypertension * Cardiac Tumors
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Seitenzahl: 490
Veröffentlichungsjahr: 2013
Contents
Contributors
Preface
Chapter 1: Cardiovascular History and Physical Examination
1.1 HISTORY
1.2 PHYSICAL EXAMINATION
1.3 BEDSIDE MANEUVERS
KEY REFERENCES
Chapter 2: Introduction to Electrocardiography
2.1 INTRODUCTION
2.2 INITIAL APPROACH TO THE ECG
2.3 LIMITATIONS
2.4 ECG PATTERNS
KEY REFERENCES
SUPPLEMENTARY ECGS
Chapter 3: Non-invasive Cardiac Imaging
3.1 INTRODUCTION
3.2 NON-STRESS IMAGING STUDIES
KEY REFERENCES
Chapter 4: Cardiac Stress Testing and the Evaluation of Chest Pain
4.1 INTRODUCTION
4.2 CHEST PAIN EVALUATION
4.3 POST-MYOCARDIAL INFARCTION
4.4 CARDIOVASCULAR STRESS TEST MODALITIES
4.5 EXERCISE STRESS TEST
4.6 RADIONUCLIDE IMAGING
4.7 STRESS ECHOCARDIOGRAPHY
KEY REFERENCES
Chapter 5: Perioperative Cardiac Evaluation
5.1 OVERVIEW
5.2 RATIONALE FOR PERIOPERATIVE CARDIAC EVALUATION
5.3 EVALUATION OF RISK
5.4 PERIOPERATIVE MEDICAL MANAGEMENT
5.5 PERIOPERATIVE STRESS TESTING AND CORONARY REVASCULARIZATION
5.6 OTHER STUDIES: PREOPERATIVE ECG AND LEFT VENTRICULAR FUNCTION ASSESSMENT
5.7 POSTOPERATIVE SURVEILLANCE
KEY REFERENCES
Chapter 6: Cardiac Resuscitation
6.1 EPIDEMIOLOGY
6.2 PHASES OF IN-HOSPITAL RESUSCITATION
KEY REFERENCES
Chapter 7: Acute Coronary Syndromes: Unstable Angina and Non-ST Elevation Myocardial Infarction
7.1 INTRODUCTION
7.2 ETIOLOGY AND PATHOPHYSIOLOGY
7.3 CLINICAL PRESENTATION
7.4 EVALUATION AND DIAGNOSTIC STUDIES
7.5 TREATMENT
7.6 HOSPITAL DISCHARGE AND POST-HOSPITAL CARE
KEY REFERENCES
Chapter 8: Acute ST Elevation Myocardial Infarction
8.1 INTRODUCTION
8.2 EPIDEMIOLOGY
8.3 PATHOPHYSIOLOGY
8.4 EVALUATION
8.5 TREATMENT
8.6 COMPLICATIONS
KEY REFERENCES
Chapter 9: Chronic Coronary Artery Disease
9.1 INTRODUCTION
9.2 PATHOPHYSIOLOGY
9.3 RISK FACTOR ASSESSMENT
9.4 CLINICAL MANIFESTATION
9.5 PHYSICAL EXAMINATION
9.6 LABORATORY AND ECG ASSESSMENT
9.7 NONINVASIVE TOOLS FOR RISK STRATIFICATION
9.8 EMERGING NONINVASIVE TESTS FOR RISK STRATIFICATION
9.9 MEDICAL TREATMENT OF CHRONIC STABLE CORONARY DISEASE
9.10 ROLE FOR REVASCULARIZATION FOR CHRONIC ANGINA
KEY REFERENCES
Chapter 10: Peripheral Arterial Disease
10.1 INTRODUCTION
10.2 EPIDEMIOLOGY, ETIOLOGY, AND NATURAL HISTORY
10.3 CLINICAL MANIFESTATIONS AND EVALUATION
10.4 TREATMENT
10.5 OTHER CONDITIONS AND VASCULAR EMERGENCIES
KEY REFERENCES
Chapter 11: Thoracic Aortic Diseases
11.1 THORACIC AORTIC ANEURYSM
11.2 ACUTE AORTIC SYNDROMES
KEY REFERENCES
Chapter 12: Systolic Heart Failure
12.1 INTRODUCTION
12.2 INCIDENCE/PREVALENCE
12.3 MORTALITY
12.4 PATHOPHYSIOLOGY OF LV SYSTOLIC DYSFUNCTION
12.5 CAUSES AND RISK FACTORS
12.6 CLINICAL HISTORY AND PHYSICAL EXAMINATION
12.7 OUTPATIENT MEDICAL MANAGEMENT
12.8 IMPLANTABLE CARIOVERTER-DEFIBRILLATOR (ICD) ± CARDIAC RESYNCHRONIZATION THERAPY
12.9 INPATIENT MEDICAL MANAGEMENT – FLOOR STATUS
12.10 INPATIENT MEDICAL MANAGEMENT – INTENSIVECARE UNIT STATUS
12.11 INPATIENT MEDICAL MANAGEMENT – INTENSIVE CARE UNIT STATUS WITH TRANSPLANT FOR ASSIST DEVICE CONSIDERATION
KEY REFERENCES
Chapter 13: Diastolic Heart Failure
13.1 INTRODUCTION
13.2 EPIDEMIOLOGY
13.3 PATHOPHYSIOLOGY
13.4 ETIOLOGIES
13.5 CLINICAL PRESENTATION
13.6 EVALUATION AND DIAGNOSTIC STUDIES
13.7 RISK STRATIFICATION
13.8 TREATMENT
13.9 TRANSITION TO OUTPATIENT CARE
KEY REFERENCES
Chapter 14: Dilated and Restrictive Cardiomyopathy
14.1 INTRODUCTION
14.2 DILATED CARDIOMYOPATHY
14.3 RESTRICTIVE CARDIOMYOPATHY
KEY REFERENCES
Chapter 15: Hypertrophic Cardiomyopathy
15.1 INTRODUCTION
15.2 PATHOPHYSIOLOGY
15.3 PATHOPHYSIOLOGY AND CLINICAL MANIFESTATIONS
15.4 EVALUATION AND DIAGNOSTIC STUDIES
15.5 TREATMENT
KEY REFERENCES
Chapter 16: Heart Transplantation and Left Ventricular Assist Devices
16.1 HEART TRANSPLANTATION
16.2 VENTRICULAR ASSIST DEVICES
Chapter 17: Syncope
17.1 PATHOPHYSIOLOGY
17.2 ETIOLOGIES
17.3 CLINICAL PRESENTATION
17.4 EVALUATION AND DIAGNOSTIC STUDIES
17.5 TREATMENT
KEY REFERENCES
Chapter 18: Approach to the Patient with a Narrow Complex Tachycardia
18.1 INTRODUCTION
18.2 DIFFERENTIAL DIAGNOSIS
18.3 NOMENCLATURE
18.4 ATRIAL FLUTTER WITH 2:1 CONDUCTION
18.5 PAROXYSMAL SUPRAVENTRICULAR TACHYCARDIAS
18.6 MECHANISMS
18.7 ELECTROCARDIOGRAPHIC DIAGNOSIS
18.8 PHYSIOLOGIC DIAGNOSIS
18.9 PHARMACOLOGIC DIAGNOSIS
18.10 DIAGNOSTIC ALGORITHM
Chapter 19: The Approach to the Patient with a Wide Complex Tachycardia
19.1 INTRODUCTION
19.2 OVERALL MECHANISMS
19.3 VENTRICULAR TACHYCARDIA
19.4 SUPRAVENTRICULAR MECHANISMS
19.5 BENIGN FORMS
19.6 DIAGNOSIS
KEY REFERENCES
Chapter 20: Atrial Fibrillation and Atrial Flutter
20.1 INTRODUCTION
20.2 PATHOPHYSIOLOGY
20.3 ETIOLOGY
20.4 CLINICAL PRESENTATION
20.5 EVALUATION AND DIAGNOSTIC STUDIES
20.6 TREATMENT
KEY REFERENCES
Chapter 21: Antiarrhythmic Drug Therapy
21.1 INTRODUCTION
21.2 PHARMACOLOGY
21.3 DISEASE-SPECIFIC THERAPY
21.4 ATRIAL FIBRILLATION AND ATRIAL FLUTTER
21.5 SUPRAVENTRICULAR TACHYCARDIA
21.6 SUMMARY
KEY REFERENCES
Chapter 22: Cardiac Pacemakers and Implantable Defibrillators
22.1 BACKGROUND
22.2 COMPONENTS OF A PACEMAKER OR ICD
22.3 INDICATIONS FOR THE IMPLANTATION OF PACEMAKERS AND ICDS
22.4 POST-IMPLANTATION CARE
22.5 EVALUATION OF AN EXISTING DEVICE
22.6 PERIOPERATIVE MANAGEMENT
KEY REFERENCES
Chapter 23: Hypertension
23.1 INTRODUCTION
23.2 ASSOCIATION WITH CARDIOVASCULAR OUTCOMES
23.3 EVALUATION
23.4 DIAGNOSIS
23.5 WORKUP
23.6 TREATMENT
23.7 MANAGING HYPERTENSION IN THE HOSPITAL
23.8 HYPERTENSIVE CRISIS
KEY REFERENCES
Chapter 24: Valvular Heart Disease
24.1 INTRODUCTION
24.2 AORTIC VALVE
24.3 MITRAL VALVE
24.4 RIGHT SIDED VALVE DISEASE
24.5 PROSTHETIC VALVES
KEY REFERENCES
Chapter 25: Infective Endocarditis
25.1 EPIDEMIOLOGY
25.2 PATHOPHYSIOLOGY
25.3 CLINICAL FEATURES
25.4 DIAGNOSIS
25.5 MICROBIOLOGY
25.6 ANTIMICROBIAL THERAPY
25.7 SURGICAL THERAPY
25.8 RESPONSE TO THERAPY
25.9 PROPHYLAXIS
25.10 CARDIOVASCULAR DEVICE INFECTION
KEY REFERENCES
Chapter 26: Pericardial Diseases
26.1 ACUTE PERICARDITIS
26.2 PERICARDIAL TAMPONADE
26.2 CONSTRICTIVE PERICARDITIS
KEY REFERENCES
Chapter 27: Pulmonary Hypertension
27.1 INTRODUCTION
27.2 ETIOLOGIES
27.3 PATHOPHYSIOLOGY
27.4 EPIDEMIOLOGY
27.5 CLINICAL PRESENTATION AND PHYSICAL EXAMINATION
27.6 EVALUATION AND DIAGNOSTIC STUDIES
27.7 TREATMENT
27.8 CARE OF THE CRITICALLY ILL PAH PATIENT
KEY REFERENCES
Chapter 28: Cardiac Tumors
28.1 INTRODUCTION
28.2 EPIDEMIOLOGY
28.3 CLINICAL MANIFESTATIONS
28.4 DIAGNOSTIC EVALUATION
28.5 TREATMENT
28.6 OTHER UNCOMMON PRIMARY CARDIAC TUMORS
KEY REFERENCES
Supplemental Images
Index
Scott A. Flanders and Sanjay Saint, Series Editors
1. Anticoagulation for the Hospitalist
Margaret C. Fang, Editor
2. Hospital Images: A Clinical Atlas
Paul B. Aronowitz, Editor
3. Becoming a Consummate Clinician: What Every Student, House Officer, and Hospital Practitioner Needs to Know
Ary L. Goldberger and Zachary D. Goldberger, Editors
4. Inpatient Perioperative Medicine Medical Consultation: Co-Management and Practice Management
Amir K. Jaffer and Paul J. Grant, Editors
5. Clinical Care Conundrums: Challenging Diagnoses in Hospital Medicine
James C. Pile, Thomas E. Baudendistel, and Brian J. Harte, MD, Editors
6. Hospitalist’s Guide to the Care of Older Patients
Brent C. Williams, Preeti N. Malani, and David H. Wesorick, Editors
7. Inpatient Cardiovascular Medicine
Brahmajee K. Nallamothu and Timir S. Baman, Editors
Copyright © 2014 by John Wiley & Sons, Inc. All rights reserved
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Library of Congress Cataloging-in-Publication Data:
Inpatient cardiovascular medicine / edited by Brahmajee K. Nallamothu, Timir S. Baman. p. ; cm. – (Hospital medicine : current concepts ; 6) Includes bibliographical references and index.
ISBN 978-0-470-61000-8 (pbk. : alk. paper) – ISBN 978-1-118-48473-9 (Mobi) – ISBN 978-1-118-48478-4 – ISBN 978-1-118-48481-4 (ePub) – ISBN 978-1-118-48482-1 (ePdf) I. Nallamothu, Brahmajee K., editor of compilation. II. Baman, Timir S., editor of compilation. III. Series: Hospital medicine, current concepts ; 6. [DNLM: 1. Cardiovascular Diseases. 2. Inpatients. WG 120] RC674 616.1′0231–dc23
2013017943
Cover image: Top left hand image – iStock file #3643872, middle left hand image – iStock file #10486652, bottom left hand image – iStock file #17324827
Printed in the United States of America
10 9 8 7 6 5 4 3 2 1
Keith Aaronson, MD, MS, Professor of Internal Medicine, Medical Director, Heart Transplant Program and Center for Circulatory Support, University of Michigan, Ann Arbor, MI, USA
Craig T. Alguire, MD, Assistant Professor, Michigan State University and Spectrum Health, Grand Rapids, MI, USA
William F. Armstrong, MD, Franklin Davis Johnston Collegiate Professor of Cardiovascular Medicine, Director, Echocardiography Laboratory, University of Michigan, Ann Arbor, MI, USA
David S. Bach, MD, Park W. Willis III Collegiate Professor of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA
Auroa Badin, MD, Assistant Professor of Clinical Medicine, University of Illinois College of Medicine at Peoria, Peoria, IL, USA
Timir S. Baman, MD, Assistant Professor of Medicine, University of Illinois College of Medicine at Peoria, Peoria, IL, USA
Anna M. Booher, MD, Assistant Professor of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA
Sanders H. Chae, MD, Assistant Professor of Medicine, University of South Florida, Tampa, FL, USA
Stanley J. Chetcuti, MD, FACC, Associate Professor, Eric J. Topol Collegiate Professor of Cardiovascular Medicine, Director, Cardiac Catheterization Laboratory, University of Michigan, Ann Arbor, MI, USA
Jennifer A. Cowger, MD, MS,Assistant Professor, Medical Director Mechanical Circulatory Support Program, Cardiovascular Center, University of Michigan, Ann Arbor, MI, USA
Thomas C. Crawford, MD, Assistant Professor of Medicine, The University of Michigan, Ann Arbor, MI, USA
Melinda B. Davis, MD, Lecturer, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA
Sharlene Day, MD, Assistant Professor of Internal Medicine, University of Michigan, Ann Arbor, MI, USA
Kim A. Eagle, MD, Albion Walter Hewlett Professor of Internal Medicine, and Director, Cardiovascular Center, University of Michigan, Ann Arbor, MI, USA
Dana P. Edelson, MD, MS, FAHA, FHM, Assistant Professor, University of Chicago Medical Center, Chicago, Illinois, USA
Anubhav Garg, MD, Lecturer, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA
Zachary D. Goldberger, MD, MS, Assistant Professor of Medicine, Division of Cardiology, University of Washington School of Medicine/Harborview Medical Center, Seattle, Washington, USA
Sascha N. Goonewardena, Lecturer, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA
P. Michael Grossman, MD, FACC, Associate Professor, Director, VA Ann Arbor Cardiac Catheterization Laboratory, University of Michigan, Ann Arbor, MI, USA
Sanjaya Gupta, MD, Assistant Professor of Internal Medicine, University of Missouri-Kansas City, and St. Luke’s Hospital, Kansas City, MI, USA
Hitinder S. Gurm, MBBS, Associate Professor of Internal Medicine, University of Michigan, Ann Arbor, MI, USA
Peter G. Hagan, MB, Assistant Professor, Director, Cardiovascular Disease Fellowship Program, University of Michigan, Ann Arbor, MI, USA
Shea E. Hogan, MD, Cardiology Fellow, University of Michigan, Ann Arbor, MI, USA
Scott L. Hummel, MD, MS, Assistant Professor of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan and Staff Cardiologist, Ann Arbor Veterans Affairs Health System, Ann Arbor, MI, USA
Karl J. Ilg, MD, Cardiac Electrophysiologist, Genesys Heart Institute, Grand Blanc, MI, USA
Renuka Jain, MD, Assistant Professor, University of Minnesota, Minneapolis, MN USA
Yogendra M. Kanthi, MD, Fellow, Cardiology and Vascular Medicine, University of Michigan, Ann Arbor, MI, USA
Christos Kasapis, MD, Interventional Cardiology Fellow, University of Michigan, Ann Arbor, MI, USA
Fareed U. Khaja, MD, Professor of Internal Medicine, University of Michigan, Ann Arbor, MI, USA
Gerald C. Koenig, MD, PhD, Assistant Professor of Medicine, Wayne State University and Henry Ford Hospital, Detroit, MI, USA
David C. Lange, MD, Fellow, Division of Cardiovascular Medicine, Cedars Sinai Medical Center, Los Angeles, CA, USA
Preeti N. Malani, MD, MSJ, Associate Professor of Internal Medicine, Divisions of Infectious Diseases and Geriatric Medicine, University of Michigan and Veterans Affairs Ann Arbor Healthcare System, Geriatric Research Education and Clinical Center (GRECC), Ann Arbor, MI, USA
Vallerie V. McLaughlin, MD, Professor of Medicine, Division of Cardiovascular Medicine, Director, Pulmonary Hypertension Program, University of Michigan, Ann Arbor, MI, USA
Brahmajee K. Nallamothu, MD, MPH,Associate Professor of Internal Medicine, University of Michigan, Ann Arbor, MI, USA
Hakan Oral, MD, Frederick G. L. Huetwell Professor of Cardiovascular Medicine, Director, Cardiac Arrhythmia Service, University of Michigan, Ann Arbor, MI, USA
Francis D. Pagani, MD, PhD, Otto Gago, M.D. Professor in Cardiac Surgery, Cardiovascular Center, University of Michigan, Ann Arbor, MI, USA
Amir B. Rabbani, MD, Cardiovascular Institute, DMC Harper University Hospital, Detroit, MI, USA
Michael C. Reed, MD, Interventional Cardiology, St. Patrick’s Hospital, Missoula, MT, and University of Washington Affiliate, Seattle, WA, USA
Adam M. Rogers, MD, Kaiser Permanente Walnut Creek Medical Center, Walnut Creek, CA, USA
Sara Saberi, MD, Lecturer, University of Michigan, Ann Arbor, MI, USA
Michael J. Shea, MD, Professor of Internal Medicine, Section Head, Cardiovascular Medicine Outpatient Service and Clinical Education, Co-Director, Aortic Valve Clinic, University of Michigan, Ann Arbor, MI, USA
Nicklaus K. Slocum, MD, Traverse Heart & Vascular, Traverse City, MI, USA
Njeri Thande, MD, Assistant Professor of Cardiology, Albert Einstein Medical School, Montefiore Hospital, Bronx, NY, USA
Michael P. Thomas, MD, Lecturer, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA
Thomas T. Tsai, MD, MSc, Director, Interventional Cardiology, Denver VA Medical Centerand Assistant Professor, University of Colorado Denverand Investigator, Colorado Cardiovascular Outcomes Research (CCOR) Group, Denver, CO, USA
Scott H. Visovatti, MD, Lecturer, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI, USA
In the United States, the number of hospital admissions in which cardiovascular diseases play a significant role is increasing due to an aging population. The care for these patients also is becoming more complex with an ever-increasing amount of novel drugs and devices being introduced that target or impact on the heart. At the same time, many patients with cardiovascular diseases are now being managed by non-cardiovascular physicians in the inpatient setting when they are admitted for other diseases. As a result, hospitalists and other inpatient practitioners are increasingly exposed to these patients but faced with anxiety and uncertainty when contemplating their proper management. Current texts may discuss various cardiovascular diseases in detail, but less often convey to the reader how to best incorporate this information most effectively into everyday clinical practice. They also rarely discuss the secondary role of cardiovascular diseases during a hospitalization, when conditions like pneumonia or peptic ulcer disease can be strongly influenced by the presence of coronary artery disease or heart failure. This book focuses on cardiovascular medicine from the perspective of the busy inpatient practitioners. It is highly practical and algorithmic in nature, and our hope is that the reader will be able to care for his or her patient directly using contemporary evidence.
We have provided a format that we believe can be easily integrated into the daily practice of a broad range of non-cardiovascular physicians (e.g., hospitalists, internal medicine residents, nurse practitioners). We have divided the book into five major sections: 1) General Principles and Conditions in Cardiovascular Medicine; 2) Ischemic Heart and Vascular Disease; 3) Heart Failure and Cardiomyopathy; 4) Syncope and Arrhythmias; and 5) Special Topics for the Inpatient Practitioner. These sections serve as broad categories so that the reader can search for their specific topic of interest. Within each section, chapters are integrated with one another. We hope this flow is apparent and useful for readers utilizing the book. We have intentionally limited the text in the chapters as much as possible. We understand the busy nature of clinical practice and tried to place a special emphasis on the integration of charts, diagrams, and algorithms to make the book more user-friendly and applicable to daily patient care. We believe this approach also allows inpatient practitioners to immediately relay information back to the patient. Finally, we highlight several important points throughout the book, reflecting the informal but critical nature of a “Take Home Point” that is so familiar to clinicians everywhere.
Of course, we hope you will find our work interesting to read, but mostly that you find it useful for your patients.
Melinda B. Davis and Michael J. Shea
Despite enormous technological advances in cardiovascular medicine, optimal care of patients with heart disease begins with a focused and thorough history and physical examination. Such an approach is needed not only to diagnose conditions but to relate findings obtained from additional testing into appropriate clinical context. A successful history and physical examination also establishes a foundation for a strong patient–physician relationship, which can greatly assist in complex discussions regarding therapeutic options.
Cardiac disease can masquerade in many different forms but classic symptoms include chest discomfort, fatigue, edema, weight gain, dyspnea, palpitations, syncope, cough, hemoptysis, and cyanosis. Symptoms of vascular disease include claudication, limb pain, edema, and skin discoloration. Patients’ descriptions of symptoms yield a great deal of information and should never be discounted (Table 1.1). Basic elements of the history include the symptom onset, the nature and severity, duration, frequency, precipitating and relieving factors, impact on daily life and employment, and similarity to prior episodes. Major risk factors for coronary artery disease include age, male gender, family history, tobacco use, hyperlipidemia, hypertension, sedentary lifestyle, obesity, and diabetes mellitus.
Table 1.1Cardiovascular Symptoms and Conditions. Patients should be questioned about the following common cardiovascular symptoms. Different features in the history can provide valuable diagnostic information.
Symptoms and conditions
Patient descriptions
Paroxysmal nocturnal dyspnea
Occurs 2–4 hours after falling asleep, causes the patient to sit upright or stand, and resolves over several minutes
Palpitations
Fluttering, skipping, pounding heartbeat; differentiate between fast and sustained versus isolated beats
Orthopnea
Shortness of breath when lying flat, typically measured by the number of pillows needed to sleep
Sleep apnea
Loud snoring, or periods of interrupted breathing
Pulmonary embolism
Usually acute onset of dyspnea
Cardiac syncope
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