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* The first single source work to deal with the two primary radiologic modalities in diagnosing and treating benign and malignant diseases of the liver, presented with clearly laid out MRI and CT correlations. Developed by an editor team led by one of the world's leading authorities in abdominal imaging, Richard C. Semelka MD. * User-friendly, atlas-style presentation, with over 1500 MRI and CT images in over 320 figures featuring state-of-the-art MR and CT imaging sequences, multidetector row CT images, 3D reformatted images, breath-hold MRI sequences, and cutting-edge MR 3T images * Highly practical approach for imaging of focal and diffuse liver lesions, complete relevant and systematic (differential) diagnostic information, the latest references to primary literature and clinical evidence, and patient management possibilities * Reflects a pattern-recognition approach to MRI and CT imaging, assisting with efficient scanning of images and assessment and diagnosis of disorders
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Cover
Title Page
Series Page
Copyright
List of Contributors
Preface
Chapter 1: The cross-sectional anatomy of the liver and normal variations
Functional anatomy
References
Chapter 2: The cross-sectional imaging techniques and diagnostic approach
MR imaging techniques
CT imaging techniques
References
Chapter 3: Safety of MRI and CT
Toxicity of contrast agents
Medical radiation and cancer
References
Chapter 4: Cystic diseases of the liver
Developmental cystic lesions
Neoplastic cystic lesions
Inflammatory cystic lesions
Miscellaneous cystic lesions
References
Chapter 5: Benign solid liver lesions
Hemangiomas
Focal nodular hyperplasia (FNH)
Hepatocellular adenomas
Liver adenomatosis
Peliosis hepatis
Angiomyolipoma and lipoma
Inflammatory myofibroblastic tumor (inflammatory pseudotumor)
References
Chapter 6: Liver metastases
Differential diagnosis
References
Chapter 7: Hepatocellular carcinoma
References
Chapter 8: Rare primary and secondary tumors of the liver
Lymphoma
Multiple myeloma
Extramedullary hematopoiesis
Epithelioid hemangioendothelioma (EHE)
Hepatoblastoma
Infantile hemangioendothelioma
Mesenchymal hamartoma
Primary sarcomas of the liver
Angiosarcoma
Undifferentiated (embryonal) sarcoma of the liver
References
Chapter 9: Cholangiocarcinoma
References
Chapter 10: Infectious diseases of the liver
Abscess
Hydatid disease
Tuberculosis
Acute viral hepatitis
Bacterial acute cholangitis
Recurrent pyogenic cholangitis
HIV-related cholangitis
References
Chapter 11: Chronic hepatitis and liver cirrhosis
References
Chapter 12: Hepatic fat and iron deposition
Fatty liver disease
Hepatic iron overload
References
Chapter 13: Inflammatory liver diseases
Primary sclerosing cholangitis (PSC)
Autoimmune hepatitis (AIH)
Primary biliary cirrhosis (PBC)
Overlap syndrome
Sarcoidosis
Acute toxic hepatitis
Wilson's Disease
Alpha-1-antitripsin deficiency
Radiation injury
References
Chapter 14: Vascular disorders of the liver
Transient hepatic enhancement differences
Portal venous thrombosis
Hepatic veno-occlusive disease
Hepatic arterial thrombosis/hepatic ischemia – infarction
Vascular malformations/fistula/aneurysms
References
Chapter 15: Post-treatment changes in the liver
Surgical resection
Hepatic transplantation
Radiation therapy
Systemic chemotherapy
Transcatheter arterial chemoembolization
Ablative therapies
References
Chapter 16: Liver trauma
References
Index
End User License Agreement
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Cover
Table of Contents
Preface
Begin Reading
Figure 1.1
Figure 1.2
Figure 1.3
Figure 1.4
Figure 1.5
Figure 1.6
Figure 1.7
Figure 1.8
Figure 1.9
Figure 1.10
Figure 2.1
Figure 2.2
Figure 2.3
Figure 2.4
Figure 2.5
Figure 2.6
Figure 2.7
Figure 2.8
Figure 2.9
Figure 2.10
Figure 2.11
Figure 2.12
Figure 2.13
Figure 2.14
Figure 2.15
Figure 2.16
Figure 2.17
Figure 2.18
Figure 2.19
Figure 2.20
Figure 2.21
Figure 2.22
Figure 2.23
Figure 2.24
Figure 2.25
Figure 2.26
Figure 2.27
Figure 2.28
Figure 2.29
Figure 2.30
Figure 2.31
Figure 2.32
Figure 2.33
Figure 2.34
Figure 2.35
Figure 2.36
Figure 2.37
Figure 2.38
Figure 4.1
Figure 4.2
Figure 4.4
Figure 4.5
Figure 4.6
Figure 4.7
Figure 4.8
Figure 4.9
Figure 4.10
Figure 4.11
Figure 4.12
Figure 4.13
Figure 4.14
Figure 4.15
Figure 4.16
Figure 4.17
Figure 4.18
Figure 4.19
Figure 4.20
Figure 5.1
Figure 5.2
Figure 5.5
Figure 5.6
Figure 5.8
Figure 5.9
Figure 5.10
Figure 5.11
Figure 5.12
Figure 5.13
Figure 5.14
Figure 5.15
Figure 5.16
Figure 5.17
Figure 5.18
Figure 5.19
Figure 5.20
Figure 5.21
Figure 5.23
Figure 5.24
Figure 5.25
Figure 5.22
Figure 5.27
Figure 5.28
Figure 5.33
Figure 5.29
Figure 5.34
Figure 5.35
Figure 5.43
Figure 5.44
Figure 5.46
Figure 5.47
Figure 5.48
Figure 5.49
Figure 5.50
Figure 5.51
Figure 5.53
Figure 6.1
Figure 6.2
Figure 6.3
Figure 6.4
Figure 6.5
Figure 6.6
Figure 6.7
Figure 6.8
Figure 6.9
Figure 6.10
Figure 6.11
Figure 6.12
Figure 6.13
Figure 6.15
Figure 6.16
Figure 6.17
Figure 6.18
Figure 6.20
Figure 6.21
Figure 6.22
Figure 6.23
Figure 6.24
Figure 6.25
Figure 6.26
Figure 6.27
Figure 6.28
Figure 6.29
Figure 6.30
Figure 6.31
Figure 6.32
Figure 6.33
Figure 6.34
Figure 6.35
Figure 6.36
Figure 6.37
Figure 7.1
Figure 7.2
Figure 7.3
Figure 7.4
Figure 7.5
Figure 7.6
Figure 7.8
Figure 7.9
Figure 7.10
Figure 7.11
Figure 7.12
Figure 7.14
Figure 7.15
Figure 7.16
Figure 7.17
Figure 7.18
Figure 7.19
Figure 7.20
Figure 7.21
Figure 7.22
Figure 7.23
Figure 7.24
Figure 7.26
Figure 8.1
Figure 8.2
Figure 8.3
Figure 8.4
Figure 8.5
Figure 8.6
Figure 8.7
Figure 8.8
Figure 8.9
Figure 8.10
Figure 8.11
Figure 8.12
Figure 9.1
Figure 9.3
Figure 9.4
Figure 9.2
Figure 9.5
Figure 9.6
Figure 9.7
Figure 9.8
Figure 9.9
Figure 9.10
Figure 10.1
Figure 10.2
Figure 10.3
Figure 10.4
Figure 10.5
Figure 10.6
Figure 10.7
Figure 10.8
Figure 10.9
Figure 10.10
Figure 10.11
Figure 10.12
Figure 10.13
Figure 10.14
Figure 10.15
Figure 10.16
Figure 10.17
Figure 10.18
Figure 10.19
Figure 11.1
Figure 11.2
Figure 11.3
Figure 11.4
Figure 11.5
Figure 11.6
Figure 11.7
Figure 11.8
Figure 11.9
Figure 11.10
Figure 11.11
Figure 11.12
Figure 11.13
Figure 11.14
Figure 11.15
Figure 11.16
Figure 11.17
Figure 11.18
Figure 11.19
Figure 11.20
Figure 11.21
Figure 11.22
Figure 11.23
Figure 11.24
Figure 11.25
Figure 11.26
Figure 11.27
Figure 11.28
Figure 11.29
Figure 11.30
Figure 11.31
Figure 11.32
Figure 11.33
Figure 11.34
Figure 12.1
Figure 12.5
Figure 12.6
Figure 12.7
Figure 12.8
Figure 12.9
Figure 12.10
Figure 12.11
Figure 12.14
Figure 12.13
Figure 12.15
Figure 12.16
Figure 12.17
Figure 12.18
Figure 12.19
Figure 12.20
Figure 13.1
Figure 13.2
Figure 13.3
Figure 13.5
Figure 13.4
Figure 13.6
Figure 13.7
Figure 13.8
Figure 13.9
Figure 13.10
Figure 13.11
Figure 13.12
Figure 13.13
Figure 13.14
Figure 13.15
Figure 13.16
Figure 14.1
Figure 14.2
Figure 14.3
Figure 14.4
Figure 14.5
Figure 14.6
Figure 14.7
Figure 14.8
Figure 14.9
Figure 14.10
Figure 14.13
Figure 14.14
Figure 14.17
Figure 14.18
Figure 14.19
Figure 14.20
Figure 14.21
Figure 14.22
Figure 14.23
Figure 14.24
Figure 14.25
Figure 4.28
Figure 15.1
Figure 15.2
Figure 15.3
Figure 15.4
Figure 15.5
Figure 15.6
Figure 15.7
Figure 15.8
Figure 15.9
Figure 15.11
Figure 15.12
Figure 15.13
Figure 15.14
Figure 15.15
Figure 15.16
Figure 15.21
Figure 15.22
Figure 15.24
Figure 16.1
Figure 16.2
Table 1.1
Table 2.1
Table 2.2
Table 2.3
Table 2.4
Table 2.5
Table 2.6
Table 2.7
Table 2.8
Table 3.1
Table 3.2
Table 3.3
Ersan Altun MD
Associate Professor of Radiology,
Attending Radiologist,
Abdominal Imaging, Department of Radiology,
The University of North Carolina at Chapel Hill, NC, USA
Mohamed El-Azzazi MD, PhD
Associate Professor of Radiology
University of Dammam, Department of Radiology, Saudi Arabia;
Consultant in the Department of Radiology
King Fahd Hospital of the University, Saudi Arabia;
Assistant Professor of Radiology
University of Al Azhar, Cairo, Egypt;
Clinical Research Scholar
Department of Radiology, University of North Carolina, Chapel Hill, NC, USA
Richard C. Semelka MD
Professor of Radiology
Abdominal Imaging, Department of Radiology
Director of MRI Services
Vice Chair of Quality and Safety
The University of North Carolina at Chapel Hill, NC, USA
Current Clinical Imaging Series
Series Editor—Richard C. Semelka
Vascular Imaging of the Central Nervous System: Physical Principles, Clinical Applications and Emerging Techniques;
Joana Ramalho, Mauricio Castillo, 2014
Other books in the Series
Imaging MSK Trauma; Andrea Donovan, Mark E. Schweitzer, 2012
Health Care Reform in Radiology; Richard C. Semelka, Jorge Elias, 2013
Text Atlas of Skeletal Age Determination; Ernesto Tomei, Richard C. Semelka, Daniel Nissman, 2014
Women's Imaging; Michele A. Brown, Haydee Ojeda-Fournier, Dragana Djilas, Mohamed El-Azzazi, Richard C. Semelka, 2014
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Library of Congress Cataloging-in-Publication Data
Liver imaging : MRI with CT correlation / editors, Ersan Altun, Mohamed El-Azzazi, Richard C. Semelka.
p. ; cm.
Includes bibliographical references and index.
ISBN 978-0-470-90625-5 (hardback)
I. Altun, Ersan, 1975-, editor. II. El-Azzazi, Mohamed, editor. III. Semelka, Richard C., editor.
[DNLM: 1. Liver Diseases–diagnosis. 2. Diagnosis, Differential. 3. Imaging, Three-Dimensional. 4. Magnetic Resonance Imaging. 5. Tomography, X-Ray Computed. WI 700]
RC847
616.3′620757–dc23
2014049427
A catalogue record for this book is available from the British Library.
Wiley also publishes its books in a variety of electronic formats. Some content that appears in print may not be available in electronic books.
Mamdoh AlObaidy
The University of North Carolina at Chapel Hill, Department of Radiology, Chapel Hill, NC, USA
King Faisal Specialist Hospital & Research Center, Department of Radiology, Riyadh, Saudi Arabia
Ersan Altun
The University of North Carolina at Chapel Hill, Department of Radiology, Chapel Hill, NC, USA
Mohamed El-Azzazi
The University of North Carolina at Chapel Hill, Department of Radiology, Chapel Hill, NC, USA
University of Dammam, Department of Radiology, Dammam, Saudi Arabia
King Fahd Hospital of the University, Department of Radiology, Khobar, Saudi Arabia
University of Al Azhar, Department of Radiology, Cairo, Egypt
Miguel Ramalho
The University of North Carolina at Chapel Hill, Department of Radiology, Chapel Hill, NC, USA
Hospital Garcia de Orta, Department of Radiology, Almada, Portugal
Richard C. Semelka
The University of North Carolina at Chapel Hill, Department of Radiology, Chapel Hill, NC, USA
In this text we describe the techniques used in modern liver imaging with MRI and CT. Although the breadth of information may be greater on MRI, it is critical to also appreciate all available information that CT conveys. This is essential as CT remains a common tool to evaluate the liver in general practice.
We have striven to show a full range of disease processes, illustrated with comparative examples for both CT and MRI. We have also drawn to the readers' attention examples and settings where MRI findings may be more informative.
Ersan Altun1, Mohamed El-Azzazi1,2,3,4, and Richard C. Semelka1
1The University of North Carolina at Chapel Hill, Department of Radiology, Chapel Hill, NC, USA
2University of Dammam, Department of Radiology, Dammam, Saudi Arabia
3King Fahd Hospital of the University, Department of Radiology, Khobar, Saudi Arabia
4University of Al Azhar, Department of Radiology, Cairo, Egypt
Knowledge of cross-sectional anatomy of the liver is essential for the determination of localization of disease processes and for their management. To have a good knowledge and sense of the cross-sectional anatomy of the liver on computerized tomography (CT) and magnetic resonance imaging (MRI) studies, the segmental anatomy of the hepatic parenchyma and the anatomy of hepatic fissures, hepatic vessels, and bile ducts should be understood.
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