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Now in full color, Practical Guide to Canine and Feline Neurology, Third Edition provides a fully updated new edition of the most complete resource on managing neurology cases in small animal practice, with video clips on a companion website.
Includes access to video clips of specific disorders and a how-to video demonstrating the neurologic assessment online and a link to a digital canine brain atlas at www.wiley.com/go/dewey/neurology
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Veröffentlichungsjahr: 2015
Third Edition
Edited by
Curtis W. Dewey, DVM, MS
Diplomate, American College of Veterinary Internal Medicine (Neurology) Diplomate, American College of Veterinary Surgeons Associate Professor and Chief – Neurology and Neurosurgery Section Department of Clinical Sciences, College of Veterinary Medicine Cornell University, Ithaca, New York
Ronaldo C. da Costa, DMV, MSc, PhD
Diplomate, American College of Veterinary Internal Medicine (Neurology); Associate Professor and Service Head, Neurology and Neurosurgery, Department of Veterinary Clinical Sciences College of Veterinary Medicine The Ohio State University, Columbus, Ohio
This edition first published 2016 © 2016 by John Wiley & Sons, Inc.
First Edition first published 2003 © 2003 Iowa State University Press Second Edition first published 2008 © 2008 Curtis Dewey
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Library of Congress Cataloging-in-Publication Data
Practical guide to canine and feline neurology / edited by Curtis W. Dewey and Ronaldo C. da Costa. – Third edition. p. ; cm. Includes index. Includes bibliographical references and index. ISBN 978-1-119-94611-3 (hardback) I. Dewey, Curtis W., editor. II. Da Costa, Ronaldo C., editor. [DNLM: 1. Dog Diseases. 2. Nervous System Diseases–veterinary. 3. Cat Diseases. SF 992.N3] SF992.N3P73 2016 636.7′08968–dc23
2015014801
A catalogue record for this book is available from the British Library.
Wiley also publishes its books in a variety of electronic formats. Some content that appears in print may not be available in electronic books.
Alexander de Lahunta, DVM, PhD, DACVIM (Neurology), DACVP.
As neurologists, Ronaldo and I shudder to think where we would be professionally without the myriad and substantial contributions that Alexander (“Sandy”) de Lahunta has made to our specialty. He has–in a career spanning nearly half a century–laid the framework for our understanding of neuroanatomy and neuropathology. It is a testament to this man's legendary and iconic status in veterinary medicine overall that any veterinarian who opens this book will immediately feel respect and gratitude for “Dr. D” and know that he deserves all the accolades we can bestow upon him. And if you would like to read about the accolades that Dr. D has earned, you should go online; they are far too numerous to fit on a textbook dedication page. Dr. D's contributions to our understanding of embryology, anatomy, neurology, and neuropathology are voluminous and ongoing. His passion has been and remains fulfilling the role of teacher. As one of his former students, I can personally attest to his unequalled skill in this arena. I can also attest to the fact that Dr. D has kept in touch with many of his students after they graduated and moved forward with further educational endeavors and careers. Years after I left Cornell as a student, I would hear of Dr. D telling his current students about something I had published in a journal. It meant a lot to know that someone I revered so highly was proud of my accomplishments. Ronaldo and I are proud of Alexander de Lahunta, as all veterinarians should be, and feel incredibly fortunate that he influenced our career paths. We dedicate this edition to someone who has positively and permanently changed the face of veterinary neurology and veterinary medicine in general—Dr. Alexander de Lahunta.
About the Editors
Notes on Contributors
Preface
Acknowledgments
About the Companion Website
1 Signalment and History: The First Considerations
Introduction
Signalment
1–3, 5
History
4
References
2 Performing the Neurologic Examination
Introduction
Tools for performing the neurologic examination
Performing the neurologic examination
1–12
Conclusion
References
Video Resources
3 Lesion Localization: Functional and Dysfunctional Neuroanatomy
Introduction
Fundamentals of lesion localization
The brain
The spinal cord
4, 9, 11, 16, 17, 19, 28, 33, 36, 48
The peripheral nervous system
Anatomy of the spinal reflexes
The autonomic nervous system and associated visceral functions
1, 10, 12, 22–24, 30, 41
References
Video Resources
4 Differential Diagnosis
Diagnostic approach
Differential diagnosis
Specific brain regions
Specific spinal regions
Consulted bibliography
5 Neurodiagnostics
Introduction
Cerebrospinal fluid (CSF) analysis
5, 7–10, 13–15, 17, 18, 20, 22, 31, 32, 36, 37, 51, 64, 84, 85, 93, 96, 97, 104, 110
Neuroimaging
25–27, 34, 44, 49, 50, 52, 58, 75, 86, 88, 102, 103, 107
Electrodiagnostics
Biopsy/exploratory surgery
16, 57, 63
References
6 Principles and Application of Magnetic Resonance Imaging (MRI)
Silke Hecht
Basic MRI physics
135, 142, 235, 278, 351, 354, 385
MR sequences
Modified spin echo (SE) sequences
23, 50, 83, 94, 95, 131, 179, 217, 269, 293, 309
Gradient recalled echo (GRE)
36, 81, 94, 104, 110, 131, 179, 208, 224, 259, 265, 279, 286, 289, 294, 319, 350, 352, 366, 383–385, 387
Functional imaging
18, 25, 37, 45, 48, 62, 126, 142, 143, 154, 194, 223, 238, 253, 268, 284, 297, 334, 352, 370, 381, 385, 399
Technical modifications
34, 56, 64, 65, 70, 99, 370, 373
Artifacts
37, 57, 100, 101, 132, 307, 406
Contrast media in MRI
62, 64, 116, 119, 150, 186, 271, 275, 276, 310, 405
MRI guided tissue sampling
49, 91, 123
MRI of the brain
Associated findings in intracranial disease
12, 14, 15, 46, 68, 71, 72, 75, 82, 86, 129, 162, 163, 165, 180, 219, 229, 236, 304, 323, 333, 348, 351, 353, 371, 376, 380, 400
Congenital brain disorders
Acquired brain disorders
Cerebrovascular disease
Metabolic, nutritional, toxic, and degenerative encephalopathies
1, 6–8, 31, 32, 55, 61, 80, 84, 85, 90, 102, 111, 113, 125, 128, 136, 159, 161, 177, 215, 218, 231, 242, 248, 251, 254, 256, 260, 270, 297, 316, 318, 333, 337, 338, 342, 357, 358, 364, 365, 372, 374, 378, 382
Trauma
2, 42, 170, 211, 257, 281
References
Magnetic resonance imaging (MRI) of the vertebral column
Generalities of Vertebral Column MRI
1–10, 12–51, 53–66, 68–70
MRI imaging techniques
2, 3, 15, 16, 16, 37–39, 42, 49, 62
Normal anatomy
Vascular diseases
Inflammatory spinal diseases
Spinal trauma
31, 32, 36, 41, 46
Congenital spinal diseases
Degenerative and developmental diseases
Closing remarks
References
7 Encephalopathies: Disorders of the Brain
Introduction
Clinical signs of brain dysfunction (see also Chapters 2 through 4)
Disorders affecting the brain in dogs and cats (Table 7.1)
References
Video Resources
8 Head-Trauma Management
Introduction
1, 17, 20, 22, 39, 56, 64, 67
Pathophysiology of head trauma
5, 6, 8, 17, 20, 22, 26, 27, 32, 34, 39, 49, 56, 64, 66, 67
Initial assessment and emergency treatment
2, 9, 11, 17, 19, 20, 22, 24, 32, 36, 46, 50, 53, 57, 59, 62–64, 74, 78, 79
(Video 17)
Secondary assessment and diagnostic procedures
1, 9, 11, 17, 20, 22, 32, 45, 64, 80
Specific medical therapy for the head- trauma victim
3–5, 9, 11, 13, 16, 17, 19, 22, 23, 27, 29, 30, 32, 33, 39, 43, 44, 48, 51, 52, 57, 58, 59, 64, 65, 68, 70–73, 75, 77, 80–82
Indications for surgery
5, 7, 9, 12, 14, 15, 17, 19, 21, 22, 28, 31, 32, 35, 39, 42, 59, 64
Intracranial pressure (ICP) monitoring
3, 5, 7, 9, 11, 17, 18, 25, 35, 39–41, 47, 49, 60, 61, 64
Prognosis and complications
10, 17, 19, 22, 54, 55, 64, 69, 76
References
Video Resources
9 Seizures and Narcolepsy
Introduction
31, 107, 127
Pathophysiology
25, 36, 38, 68, 98
Types of seizures
9, 13, 19, 25, 45, 48, 56, 68, 80, 91, 97, 100, 125, 139
Stages of a seizure
9, 13, 56, 127
Epilepsy
9, 13, 97, 127
Idiopathic epilepsy
3, 11, 23, 36, 37, 39, 40, 44, 49, 50, 58–62, 66, 74, 78, 83, 86, 87, 89, 101, 112, 115, 122
Diagnostic evaluation
12, 70, 84, 117
General aspects of treatment
10, 15, 26, 31, 41, 55, 127
First-line antiseizure drugs (Table 9.1)
Second-line drugs
Drugs under investigation for dogs
69, 140
Ineffective and contraindicated anticonvulsant drugs
15, 31, 111, 120, 126, 127
Other treatments
4, 5, 46, 64, 65, 77, 85, 90, 121, 142
Refractory epilepsy
25, 31, 82, 96, 127, 133
Status epilepticus and cluster seizures
7, 34, 72, 94, 95, 99, 107, 116, 119, 123, 137
Introduction
Pathophysiology
Clinical signs
Diagnosis
Treatment
Prognosis
References
Video Resources
10 Involuntary Movements and Paroxysmal Disorders
Introduction
Types of involuntary movements
Diagnostic approach
Establishing the etiology using clinical characteristics
References
11 Disorders of Hearing and Balance: The Vestibulocochlear Nerve (CN VIII) and Associated Structures
Functional neuroanatomy of the vestibular system
22, 27, 34, 45, 67, 86, 122
Functional neuroanatomy of the auditory system
15, 27, 34, 45, 90
Clinical evaluation of the vestibular system
4, 10, 15, 31, 34, 45, 57, 67, 74, 86, 90, 126
Clinical evaluation of the auditory system
34, 90, 116
Diseases affecting the peripheral vestibular system
4, 7, 9, 15, 19, 34, 36, 41, 48, 55, 61, 64, 65, 66, 68, 71, 80, 82, 83, 86, 92, 104, 105, 113, 119, 122, 128, 129, 137
Diseases affecting the central vestibular system
4–6, 11–13, 15–18, 20, 24, 26, 28, 29, 32, 34–37, 42–44, 46–49, 54–57, 59–61, 64, 69, 70, 72, 73, 77, 79, 80, 83, 85–89, 91, 94, 97, 100, 101, 103, 104, 106, 112, 119, 121, 123, 124, 128, 129, 134, 136, 138, 139
Diagnostic tests
3, 4, 6, 13, 15, 19, 34, 44, 50, 62, 71, 75, 78, 82, 84, 107, 108, 115, 117, 118, 119, 123, 128, 130, 133, 135
References
Video Resources
12 Cerebellar Diseases and Tremor Syndromes
Introduction
3, 15, 18, 28, 59, 86, 100, 114, 139, 152, 175
Divisions of the cerebellum
15, 35, 59, 86, 100, 114, 138, 210
Microscopic anatomy of the cerebellum
15, 35, 59, 86, 89, 210, 211
Afferent projections to the cerebellum
15, 18, 35, 59, 86, 89, 161, 210, 211
Efferent projections from the cerebellum
3, 15, 18, 35, 59, 86, 91
Functions of the cerebellum
3, 12, 15, 18, 23, 24, 28, 48, 56, 59, 102, 107, 114, 132, 133, 134, 135, 136, 137, 147, 152, 157, 216
Clinical signs of cerebellar dysfunction
3, 15, 18, 59, 86, 100, 119, 155
(Video 9)
Disorders of the cerebellum
1–4, 6–8, 10, 13–22, 25, 27–34, 36, 37, 39–43, 45–47, 49–52, 57–62, 64, 66–71, 73–77, 79–82, 84–88, 92, 95–101, 103–106, 108–113, 115–120, 122–128, 130, 140, 141, 143–146, 148–152, 154, 156, 158, 163–170, 172–174, 176–187, 189, 190, 192–199, 202–204, 209, 211, 213, 218–220
Pathophysiology and classification
Tremor disorders in dogs and cats
References
Video Resources
13 Myelopathies: Disorders of the Spinal Cord
Clinical signs of spinal cord dysfunction
73, 78, 78, 146
Disorders affecting the spinal cord in dogs and cats (Table 13.1)
References
Video Resources
14 Disorders of the Cauda Equina
Clinical signs of cauda equina dysfunction
Disorders affecting the cauda equina in dogs and cats (Table 14.1)
References
Video Resources
15 Spinal Trauma Management
Introduction
Pathophysiology of spinal trauma
2–5, 8, 19, 21, 22, 25, 27, 30–32, 38, 40, 41, 48, 50, 53, 61, 62, 65, 69, 71, 75, 78
Initial assessment and emergency treatment
1, 23, 29, 45, 46, 65–67, 72
Diagnostic imaging procedures
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