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Expertly authored by the world’s leading specialists in the field, Prevention of Diabetes is the definitive guide for better preventative diabetes care.
Using an evidence-based approach, it outlines the very latest in the identification of people at high risk for type 2 diabetes and how best to use interventional methods such as screening at-risk individuals, pharmaceutical intervention and lifestyle changes.
In addition, it will provide healthcare professionals with the clinical knowledge required to clearly identify the early symptoms of diabetes, enabling them to provide their patients with better clinical care and helping avoid the onset of full-blown diabetes.
Also covered are both the health economics of establishing, and the methods of implement/delivering targeted prevention programmes into clinical and health care practice, based on the vast experience of the editors due to their involvement in such programmes.
Prevention of Diabetes provides clear and expert information in a practical, accessible way, and is ideal reading for all those with an interest in the prevention of diabetes and obesity, such as public health workers, specialists in diabetes and obesity, and GP’s seeing patients with early onset or pre-diabetes symptoms.
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Seitenzahl: 374
Veröffentlichungsjahr: 2013
Table of Contents
Title page
Copyright page
Contributors
Preface
CHAPTER 1: What have we learned from the number of clinical trials?
Introduction
Major lifestyle trials in prevention of T2D
Clinical trial evidence of the effect of lifestyle components on T2D risk
CHAPTER 2: Identification of target populations for intervention
Introduction
Risk factors for type 2 diabetes
Target populations for intervention
Categorization of glucose abnormalities
Detection of people at high risk for diabetes: scoring systems
Strategies to identify people at high risk for diabetes
Conclusions
CHAPTER 3: Diagnosis of prediabetes and diabetes prevention
Introduction
Historical synopsis
Current definition, mechanisms, and consequences of prediabetes
Testing for prediabetes: Methodologic and epidemiologic considerations
Where are we now?
CHAPTER 4: What do we know about recruitment and retention in diabetes prevention programs? An Australian perspective
Introduction
Life! Taking Action on Diabetes program
Lessons learned
Conclusions
Acknowledgments
CHAPTER 5: Depression and diabetes prevention
Introduction
Depression as a risk factor for diabetes
Potential mechanisms linking diabetes and depression
Emotional aspects in diabetes prevention
Effects of diabetes prevention programs on emotional well-being
CHAPTER 6: Diabetes prevention in a challenging environment
CHAPTER 7: Global migration and prevention of diabetes
Epidemiologic trends of diabetes in Asian Indians and migrant South Asians
Risk factors for type 2 diabetes in Asian Indians and migrant South Asians
Preventive strategies
Conclusions
CHAPTER 8: Diabetes prevention in practice: examples from the real world
Introduction
The Greek experience
The Polish experience
Discussion
CHAPTER 9: Quality management and outcome evaluation in diabetes prevention
Introduction
Quality in diabetes care
Quality in health promotion and primary prevention
Classification of quality and outcome indicators
Quality criteria and indicators
Outcome evaluation indicators
Discussion
Acknowledgment
CHAPTER 10: Training of prevention managers
Curriculum development for the training of prevention managers in the field of type 2 diabetes prevention
Description of basic organizational conditions
Definition of learning objectives, methods, and materials
Control of learning objectives
The PM training course
CHAPTER 11: Prevention of type 2 diabetes: the role of physical activity
Physical activity and health – an evolutionary perspective
Evidence for the role of physical activity in the prevention of type 2 diabetes
How much is enough?
Physical activity and body weight
Promotion of physical activity in diabetes prevention: what works
Physical activity and the detection of risk
Physical activity throughout life
Sedentary behavior: more than just physical inactivity
Conclusions
CHAPTER 12: Overview: Potentials of new media for the training of health educators in the field of diabetes prevention
Introduction
Didactic concepts and e-learning approaches
Web 2.0 and social software
New media in diabetes prevention
Conclusions
Outlook
CHAPTER 13: Practical approach to the implementation of diabetes prevention
Epidemiology
Combining forces
Screening and treating prediabetes
National programs targeted at the obesity epidemic
Index
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Library of Congress Cataloging-in-Publication Data
Prevention of diabetes / edited by Peter Schwarz, Prasuna Reddy.
p. ; cm.
Includes bibliographical references and index.
ISBN 978-0-470-65465-1 (pbk. : alk. paper) – ISBN 978-1-118-66129-1 (ePDF) – ISBN 978-1-118-66130-7 (Mobi) – ISBN 978-1-118-66131-4 (ePub) – ISBN 978-1-118-66132-1
I. Schwarz, Peter (Physician) II. Reddy, Prasuna.
[DNLM: 1. Diabetes Mellitus, Type 2–prevention & control. 2. Diabetes Mellitus, Type 2–complications. 3. Diabetes Mellitus, Type 2–diagnosis. 4. Evidence-Based Medicine–education. 5. Risk Factors. WK 810]
RC660.4
616.4′62–dc23
2013013319
A catalogue record for this book is available from the British Library.
Wiley also publishes its books in a variety of electronic formats. Some content that appears in print may not be available in electronic books.
Cover image: © Garth Stewart; © Shutterstock / eltoro69; iStockPhoto / dutch icon
Cover design by Garth Stewart
Contributors
Abdul Basit MBBS, FRCP(Lon)
Director, Baqai Institute of Diabetology and Endocrinology (BIDE)
Professor of Medicine
Baqai Medical University
Karachi, Pakistan
Michael Bergman MD, FACP
Clinical Professor of Medicine
NYU School of Medicine
Division of Endocrinology
NYU Diabetes and Endocrine Associates
New York, NY, USA
Bishwajit Bhowmik MBBS, DDM
Research Fellow – Diabetes
Institute of Health and Society
Faculty of Medicine
University of Oslo; and
Manager, Diabetes Prevention Intervention Study (DPIS)
Oslo, Norway
Martin Buysschaert MD, PhD
Professor of Medicine
Head of the Department
Université Catholique de Louvain (UCL)
University Clinic Saint-Luc
Department of Endocrinology and Diabetology
Brussels, Belgium
Avivit Cahn MD
Attending Physician
Endocrinology and Metabolism Service; and
The Diabetes Unit
Department of Medicine
Hadassah-Hebrew University Medical Center
Jerusalem, Israel
Stephen Colagiuri MD
Professor of Metabolic Health
Boden Institute of Obesity, Nutrition, Exercise, and Eating Disorders
University of Sydney
Sydney, NSW, Australia
Emmanuel Cosson MD, PhD
Professor
Department of Endocrinology Diabetology Nutrition
Jean Verdier Hospital, AP-HP
Paris Nord University, CRNH-IdF
Bondy, France
Melanie Davies MD
Professor of Diabetes Medicine
Diabetes Research Unit
College of Medicine, Biological
Sciences and Psychology
University of Leicester
Leicester, UK
Martin R. Fischer MD, MME (Berne)
Professor of Internal Medicine and Medical Education
Department of Medical Education
Munich University Hospital
Munich, Germany
Alice Gibson BSc
Research Officer
Boden Institute of Obesity, Nutrition, Exercise and Eating Disorders
University of Sydney
Sydney, NSW, Australia
Aleksandra Gilis-Januszewska
Chair, Department of Endocrinology
Collegium Medicum, Jagiellonian University
Krakow, Poland
Norbert Hermanns PhD
Professor of Clinical Psychology
Department of Clinical Psychology, University of Bamberg, Bamberg; and
Director, Research Institute of Diabetes Academy Mergentheim (FIDAM)
Bad Mergentheim, Germany
Akhtar Hussain MD, PhD, DSc
Professor of Chronic Diseases – Diabetes
Institute of Health and Society, Faculty of Medicine
University of Oslo; and
Coordinator, Diabetes Prevention Intervention Study (DPIS)
Oslo, Norway
Baruch Itzhak MD
Specialist in Family Medicine
Israel National Diabetes Prevention Committee
Jerusalem, Israel
Greg Johnson B Pharm, Dip Hosp Pharm, MBA
Chief Executive Officer
Diabetes Australia
Adjunct Professor, Faculty of Health
Deakin University
Melbourne, VIC, Australia
Kamlesh Khunti MD, PhD
Professor of Primary Care Diabetes and Vascular Medicine
Diabetes Research Unit
College of Medicine, Biological
Sciences and Psychology
University of Leicester
Leicester, UK
Peter Kronsbein PhD
Professor of Counselling and Nutrition Education
Niederrhein University of Applied Sciences
Faculty of Nutrition, Food, and Hospitality Sciences
Mönchengladbach, Germany
Rüdiger Landgraf MD
Professor of Internal Medicine, Endocrinology and Diabetology
German Diabetes Foundation
Munich, Germany
Stavros Liatis MD
Senior Consultant in Internal Medicine and Diabetology
First Department of Propaedeutic Medicine
Athens University Medical School
Laiko General Hospital
Athens, Greece
Jaana Lindström PhD
Research Manager
Department of Chronic Disease Prevention
Diabetes Prevention Unit
National Institute for Health and Welfare (THL)
Helsinki, Finland
Konstantinos Makrilakis MD, MPH, PhD
Assistant Professor of Internal Medicine
First Department of Propaedeutic Medicine
Athens University Medical School
Laiko General Hospital
Athens, Greece
Andrew Milat BHMS Ed (Hons), MPH (Hons)
Associate Director, Evidence and Evaluation
New South Wales (NSW) Ministry of Health
North Sydney, NSW, Australia
Markku Peltonen PhD
Director and Adjunct Professor
Department of Chronic Disease Prevention
National Institute for Health and Welfare (THL)
Helsinki, Finland
Itamar Raz MD
Professor of Medicine
The Diabetes Unit, Department of Medicine
Hadassah-Hebrew University Medical Center
Jerusalem, Israel
Prasuna Reddy BA, MA, PhD, MAPS
Professor and Director CRRMH
School of Medicine and Public Health
University of Newcastle
Callaghan, NSW, Australia
Musarrat Riaz MBBS, FCPS
Consultant Diabetologist
Baqai Institute of Diabetology & Endocrinology (BIDE)
Karachi, Pakistan
Peter Schwarz MD, PhD
Head, Division for Prevention and Care of Diabetes Mellitus
Department of Medicine III
University of Dresden
Dresden, Germany
Jane Shill BSc, MSc
Evaluation and Research Coordinator
Life! program
Diabetes Australia – Victoria
Melbourne, VIC, Australia
Victoria Telle Hjellset PhD
Post Doctoral Fellow
Institute of General Practice and Community Medicine
Department of Preventive Medicine and Epidemiology
University of Oslo and
Norwegian University of Life Sciences
Oslo, Norway
Amy Timoshanko PhD
Prevention and Health Promotion Manager
Diabetes Australia – Victoria
Melbourne, VIC, Australia
Daniel Tolks Diplom-Gesundheitswirt
Research Fellow
Department of Medical Education
Munich University Hospital
Munich, Germany
Paul Valensi MD
Professor, Head of the Department
Department of Endocrinology Diabetology Nutrition
Jean Verdier Hospital, AP-HP
Paris Nord University, CRNH-IdF
Bondy, France
Philip Vita BSc, MAppPsych
Director, Sydney Diabetes Prevention Program
Boden Institute of Obesity, Nutrition, Exercise and Eating Disorders
University of Sydney and Sydney Local Health District
Sydney, NSW, Australia
Thomas Yates PhD
Senior Lecturer in Physical Activity
Sedentary Behaviour and Health Diabetes Research Unit
College of Medicine, Biological
Sciences and Psychology
University of Leicester
Leicester, UK
Preface
Noncommunicable diseases represent a great and growing threat to health and development worldwide. Four of these diseases: cancers, diabetes, cardiovascular diseases, and chronic respiratory diseases, are currently responsible for 60% of all deaths globally, with 80% in low and middle-income countries.
Diabetes is particularly challenging as it is increasing rapidly. The International Diabetes Federation predicts that in the next 17 years, the number of people worldwide living with diabetes will increase from 285 million to 552 million. Diabetes is a disease of poverty; it is increasing most rapidly in poor vulnerable populations and resource-poor settings. A large segment of the world's population is at high risk of diabetes, but only a very small proportion are screened or diagnosed.
Yet diabetes, like cardiovascular diseases and cancers, is largely preventable. Up to 80% of heart disease, stroke, and type 2 diabetes could be prevented by eliminating shared risk factors, mainly tobacco use, unhealthy diet, and physical inactivity. While sedentary behavior and poor nutrition, especially excessive consumption of calories, salt, saturated fat and sugar, increase the risk of noncommunicable diseases, there is good evidence that healthful diets and regular physical activity can reduce the risk of diabetes and cardiovascular disease.
The chapters in this book are examples of translational research, intervention trials, practical programs and designs required to address key challenges in the global action to prevent diabetes.
The identification of target populations for intervention is the theme of a chapter from Paris Nord University researchers. They describe a screening strategy for identifying glycemic abnormalities to detect prediabetes and type 2 diabetes. Researchers Buysschaert and Bergman from Belgium and the US respectively, discuss diagnosis of prediabetes and diabetes prevention. They focus on the status of diagnostic criteria related to glucose and more recently HbA1c levels. The development of quality and outcome standards for diabetes prevention is the topic of a chapter by Peltonen and Landgraf. They provide important information on quality indicators and outcome evaluation indicators that allow for measurement and comparative evaluation of different diabetes prevention approaches.
The comorbidity of diabetes and depression is the topic of a chapter by Hermanns. This renowned researcher discusses the advantages of a structured diabetes prevention program that also addresses psychological aspects of lifestyle modification. The role of physical activity in prevention of type 2 diabetes is covered in a chapter by researchers from the University of Leicester. The authors describe ways of initiating physical activity behavior change and the implications of the sedentary behavior paradigm.
A community-based lifestyle prevention program for prevention of diabetes is described in a chapter by a team of researchers from Greece, Poland, and Germany. The evaluation of the program in cohorts in two different communities and countries, showed improvement in cardiovascular risk factors and benefits in weight loss. A team of researchers from Israel has provided a chapter describing implementation of diabetes prevention programs directed at two levels: high risk populations and whole populations. The chapter emphasizes creating health promoting environments and quality improvement of interventional programs.
Implementing diabetes prevention programs in South Asia raises a particular set of challenges that are discussed by researchers from Pakistan. They describe the need for multidisciplinary teams to be active in primary prevention, and public health campaigns focused on children and adolescents. Another chapter considers the epidemiologic trends of diabetes among Asian Indians and migrant South Asians. The authors note that government prevention policy needs to consider training of healthcare practitioners in effective strategies for migrant groups.
An Australian team has looked closely at recruitment and retention in diabetes prevention programs. They describe the difficulties and possible solutions of attracting high risk participants into government-funded group programs, and note the under-representation of men and the socially disadvantaged. Training health professionals in diabetes prevention using new media is discussed by Tolles and Fischer from Germany. They provide an intriguing overview of e-learning approaches, web technologies, and the uses of new media in health promotion and diabetes prevention.
The chapters in this book represent advances in the application of research to address the prevention of diabetes, and more broadly, the prevention of noncommunicable diseases, which account for a large share of the global disease burden.
Professor Peter Schwarz
Professor Prasuna Reddy
CHAPTER 1
What have we learned from the number of clinical trials?
Jaana Lindström
Department of Chronic Disease Prevention, Diabetes Prevention Unit, National Institute for Health and Welfare (THL), Helsinki, Finland
The primary prevention of type 2 diabetes (T2D) was originally proposed by Dr. E. Joslin in 1921 [1]. He commented on how obese people are more likely to have diabetes than their slimmer neighbors. Indeed, to be able to prevent a chronic disease such as T2D it is necessary to have knowledge about its modifiable risk factors and natural history. Furthermore, there should be a preclinical phase or a “window of opportunity” for intervention as well as a feasible screening tool to identify high-risk individuals. In addition, the efficacy of the intervention has to be proven in a clinical trial setting.
T2D is a very expensive disease – about 10–15% of the total health care costs in developed countries are spent to treat T2D and, in particular, its complications [2,3]. To avoid late complications of T2D and related costs, prevention of T2D itself is therefore desirable. There are some “natural” experiments in which ethnic groups have experienced rapid westernization and with it a rapid increase in the rates of obesity and T2D [4]. Therefore it is logical to assume that by reversing these lifestyle changes it would be possible to prevent the development of the disease. Such a potential for reversibility has been shown among Australian Aboriginals [5]. In these experiments hyperglycemic people returned to living in a traditional hunter–gatherer way of life – an ultimate lifestyle change not suitable for everybody.
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