The HPLC-MS Handbook for Practitioners E-Book
87,99 €
Mehr erfahren.
- Herausgeber: Wiley-VCH Verlag GmbH & Co. KGaA
- Kategorie: Wissenschaft und neue Technologien
- Sprache: Englisch
Filling the gap for an expert text dealing exclusively with the practical aspects of HPLC-MS coupling, this concise, compact, and clear book provides detailed information to enable users to employ the method most efficiently.
Following an overview of the current state of HPLC-MS and its instrumentation, the text goes on to discuss all relevant aspects of method development. A chapter on tips and tricks is followed by user reports on the advantages - and pitfalls - of applying the method in real-life scenarios. The whole is rounded off by a look at future developments by renowned manufacturers.
Sie lesen das E-Book in den Legimi-Apps auf:
Seitenzahl: 432
Veröffentlichungsjahr: 2017
Ähnliche
Table of Contents
Cover
Title
Copyright
Preface
The Structure of
HPLC-MS for Practitioners
List of Contributors
Part I: Overview, Pitfalls, Hardware-Requirements
1 State of the Art in the LC/MS
1.1 Introduction
1.2 Ionization Methods at Atmospheric Pressure
1.3 Mass Analyzer
1.4 Future Developments
1.5 What Should You Look for When Buying a Mass Spectrometer?
References
2 Technical Aspects and Pitfalls of LC/MS Hyphenation
2.1 Instrumental Requirements for LC/MS Analysis – Configuring the Right System for Your Analytical Challenge
2.2 LC/MS Method Development and HPLC Method Adaptation – How to Make My LC Fit for MS?
2.3 Pitfalls and Error Sources – Sometimes Things Do Go Wrong
2.4 Conclusion
2.5 Abbreviations
References
3 Aspects of the Development of Methods in LC/MS Coupling
3.1 Introduction
3.2 From Target to Screening Analysis
3.3 The Optimization of Parameters in Chromatography and Mass Spectrometry
References
Part II: Tips, Examples, Trends
4 LC/MS for Everybody/for Everything? – LC/MS Tips
4.1 Introduction
4.2 Tip Number 1
4.3 Tip Number 2
4.4 Tip Number 3
4.5 Tip Number 4
4.6 Tip Number 5
4.7 Tip Number 6
4.8 Tip Number 7
4.9 Tip Number 8
4.10 Need More Help?
References
Part III: User Reports
5 LC Coupled to MS – a User Report
References
6 Problem Solving with HPLC/MS – a Practical View from Practitioners
6.1 Introduction and Scope
6.2 Case Example 1
6.3 Case Example 2
6.4 Case Example 3
6.5 Case Example 4
7 LC/MS from the Perspective ofaMaintenance Engineer
7.1 Introduction and Historical Summary
7.2 Spray Techniques
7.3 Passage Through the Ion Path
7.4 The Analyzer
7.5 Maintenance
References
Part IV: Vendor’s Reports
8 LC/MS – the Past, Present, and Future
9 Vendor’s Report – SCIEX
10 Manufacturer Report – Thermo Fisher Scientific
10.1 Liquid Chromatography for LC/MS
10.2 Mass Spectrometry for LC/MS
10.3 Integrated LC/MS Solutions
10.4 Software
References
About the Authors
Index
End User License Agreement
Guide
Cover
Table of Contents
Begin Reading
Pages
C1
III
IV
V
XI
XIII
XIV
XV
XVI
1
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
139
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
169
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
189
190
191
192
193
194
195
196
197
198
199
201
203
204
205
207
208
209
210
211
212
213
214
215
216
217
218
219
221
222
223
224
225
227
228
229
230
231
232
233
e1
Edited byStavros Kromidas
The HPLC-MS Handbook for Practitioners
Editor
Dr. Stavros Kromidas
Consultant, Saarbrücken
Breslauer Str. 366440 BlieskastelGermany
All books published by Wiley-VCH are carefully produced. Nevertheless, authors, editors, and publisher do not warrant the information contained in these books, including this book, to be free of errors. Readers are advised to keep in mind that statements, data, illustrations, procedural details or other items may inadvertently be inaccurate.
Library of Congress Card No.:
applied for
British Library Cataloguing-in-Publication Data:
A catalogue record for this book is available from the British Library.
Bibliographic information published by the Deutsche Nationalbibliothek
The Deutsche Nationalbibliothek lists this publication in the Deutsche Nationalbibliografie; detailed bibliographic data are available on the Internet at http://dnb.d-nb.de.
© 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Boschstr. 12, 69469 Weinheim, Germany
