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A special edition of the book Science Without Borders is dedicated to the most important problem of modern civilization at present - the fight against a pandemic of COVID-19. The authors of this issue offer their concept of reducing the risks of coronavirus infection and mortality from it before the advent of the vaccine. Based on the analysis of long-term clinical and laboratory tests of the drug "AZEOMED", the authors give convincing arguments in support of the possibility of effective use of the drug "AZEOMED" in the process of prevention and treatment of COVID-19. Clinical and laboratory studies of the mineral composition "AZEOMED" were coordinated and funded by the International Scientific and Technical Complex "Intergeo-Tethys". The book contains data on analogues of the drug AZEOMED produced in different countries.
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International Council for Scientific Development
INTERNATIONAL ACADEMY
OF SCIENCE H&E
SCIENCE WITHOUT
BORDERS
2020
ISSN 2070-0334
ISBN 978-3969-177-72-3
Innsbruck – Baku - 2020
Co-chairs
Academician, Prof. Dr. Elchin Khalilov, President of ICSD/IAS-AS H&E (Baku, Azerbaijan)
Academician, Prof. Dr. Walter Kofler, President of ICSD/IAS H&E (Innsbruck, Austria)
MEMBERS OFEDITORIAL BOARD:
Akad. Prof. Dr. R. Steinacker (meteorology), Austria; Acad. Prof. Dr. K. Hecht (medicine), Germany; Acad. Prof. Dr. G. Tellnes (medicine), Norway; Acad. Prof. Dr. Z. Samedzade (economy), Azerbaijan; Prof. Dr. WangLanmin (seismology), China; Acad. Prof. Dr. V. Starostenko (geophysics), Ukraine; Acad. Prof. Dr. P. Z. Mamedov (geophysics), Azerbaijan; Acad. Prof. Dr. R.Lobato (journalism), Brazil; Acad. Prof. Dr. O.Glazachev (medicine), Russia; Acad. Prof. Dr. G.Fumarola (ecology), Italy; Acad. Prof. Dr.M.Gigolashvili (astrophysics), Georgia; Acad. Prof. Dr. M. N. Veliyeva (pharmaceuticals), Azerbaijan; Acad. Dr. P.Keshavan (biology), India;
Authors: Prof. Dr. med. Karl Hecht ([email protected]), Prof. Dr. Elchin Khalilov ([email protected]), Dr. med. Ilse Triebnig ([email protected]), PhD.Tamila Khalilova ([email protected]), Prof. Dr. Mahbuba Veliyeva ([email protected]), Prof. Dr. Farkhanda Sadikhova ([email protected]), Dr. Yelena Savoley ([email protected])
Science Without Borders. COVID-19: A global problem for modern civilization.
Transactions of the International Academy of Science H&E. Vol. 5. Specian Edition. Innsbruck-Baku, SWB, 2020
A special edition of the book “Science Without Borders” is dedicated to the most important problem of modern civilization at present - the fight against a pandemic of COVID-19. The authors of this issue offer their concept of reducing the risks of coronavirus infection and mortality from it before the advent of the vaccine. Based on the analysis of long-term clinical and laboratory tests of the drug “«AZEOMED»”, the authors give convincing arguments in support of the possibility of effective use of the drug “«AZEOMED»” in the process of prevention and treatment of COVID-19. Clinical and laboratory studies of the mineral composition “«AZEOMED»” were coordinated and funded by the International Scientific and Technical Complex "Intergeo-Tethys". The book contains data on analogues of the drug AZEOMED produced in different countries.
©International Acaedemy of Science H&E, Intergeo-Tethys Ltd.
ISSN 2070-0334
ISBN 978-3969-177-73-3
CONTENTS
FOREWORD
Karl Hecht, Elchin Khalilov, Ilse Triebnig, Tamila Khalilova,
Mahbuba Valiyeva,Farkhanda Sadikhova, Yelena Savoley
PROSPECTS FOR APPLICATION OF «AZEOMED»
MINERAL COMPOSITION FOR PREVENTION
AND TREATMENT OF COVID-19 AND OTHER
SEVERE ILLNESS
1. COVID-19 PANDEMIC - MODERN CHALLENGES
FOR HUMANITY AND POSSIBLE WAYS TO
OVERCOME THEMby Dr. Tamila Khalilova
2. ZEOLITE - CLINOPTILOLITE OF THE AYDAG
DEPOSIT, ITS STRUCTURE AND PHYSICOCHEMICAL PROPERTIES
by Prof. Dr. Elchin Khalilov
3. PHYSIOLOGICAL, BIOPHYSICAL AND BIOCHEMICAL
MECHANISMS OF THE INFLUENCE OF NATURAL
ZEOLITE-CLINOPTILOLITE ON THE HUMAN ORGANISM
by Prof. Dr. med. Karl Hecht, Dr. Yelena Savoley
4. SCIENTIFIC RESEARCH AND EXPERIENCE OF USING OF
NATURAL ZEOLITE-CLINOPTILOLITE IN THE PREVENTION
AND TREATMENT OF VARIOUS DISEASES
by Dr. med. Ilse Triebnig
5. EXPERIENCE OF APPLICATION OF THE «AZEOMED»
MINERAL COMPLEX FOR PREVENTION AND
TREATMENT OF INFECTIOUS DISEASES
6. RESULTS OF RESEARCHES OF THE «AZEOMED»
MINERAL COMPLEX AS AN IMMUNOSTIMULANT
by Prof, Doctor of Pharmacy Mahbuba Veliyeva
7. SORPTION ACTIVITY OF THE «AZEOMED» MINERAL
COMPLEX AGAINST PATHOGENIC VIRUSES
AND BACTERIA by Prof. Dr. med. Farhanda Sadykhova, Azerbaijan
8. THE EXPERIENCE OF USING OF NATURAL ZEOLITE-CLINOPTILOLITE
IN THE TREATMENT OF CANCER
9. CLINICAL AND LABORATORY RESULTS
TESTS OF THE «AZEOMED» MINERAL COMPLEX
10. PROSPECTS FOR APPLICATION OF THE «AZEOMED»
MINERAL COMPLEX TO REDUCE THE RISK OF
INCIDENCE AND MORTALITY FROM COVID-19
CONCLUSION
WHAT ANALOGUES OF THE «AZEOMED»
MINERAL COMPLEX EXIST IN THE WORLD?
REFERENCES
AUTHORS INFORMATION
FOREWORD
A special edition of the book “Science Without Borders” is dedicated to the most important problem of modern civilization at present - the fight against a pandemic of COVID-19. The authors of this edition of the book presented the results of an analysis of the development of a pandemic in the world in comparison with the development of the epidemiological situation in China. An attempt has been made to understand the main reasons that in many countries of the world the pandemic situation is developing according to a more pessimistic scenario than in Chine.
The authors of this issue offer their concept of reducing the risks of coronavirus infection and mortality from it before the advent of the vaccine. The book provides relevant results of 20 years of research on clinical and laboratory tests of the «AZEOMED» mineral complex (mineral food supplement), which was developed as part of the joint scientific program of the Azerbaijan Section of the International Academy of Sciences and the International Scientific and Technical Complex "Intergeo-Tethys".
Based on the analysis of long-term clinical and laboratory tests of the mineral complex «AZEOMED», the authors give convincing arguments in support of the possibility of effective use of the mineral complex «AZEOMED» in the process of prevention and treatment of COVID-19.At the end of the book, information is given on analogues of the AZEOMED mineral complex based on natural clinoptilolite-zeolite, which are produced in various countries.
SPECIAL EDITION
COVID-19: A GLOBAL PROBLEM FOR MODERN CIVILIZATION
PROSPECTS FOR APPLICATION OF «AZEOMED» MINERAL COMPLEX FOR PREVENTION AND TREATMENT OF COVID-19 AND OTHER SEVERE ILLNESS
1Prof. Dr. med. Karl Hecht, 2,3Prof. Dr. Elchin Khalilov, 4Dr. med. Ilse Triebnig, 5,6PhD.Tamila Khalilova, 7Prof. Dr. Mahbuba Veliyeva, 8Prof. Dr. Farkhanda Sadikhova, 1Dr. Yelena Savoley
4WOSCO SWB (Carinthia, Austria); [email protected]
7Department of Pharmaceutical Technology and Management
of Azerbaijan Medical University (Azerbaijan, Baku);[email protected]
SUMMARY
The paper discusses the results of 20 years of clinical and laboratory studies of the effectiveness of the mineral composition - food supplement «AZEOMED» based on natural zeolite - clinoptilolite of the Aydag deposit of Azerbaijan. The results of comprehensive studies published in scientific papers and having official conclusions of state medical institutions and scientists of Azerbaijan, Germany, Austria and Russia made it possible to establish the high effectiveness of the drug «AZEOMED» in the prevention and treatment of severe infectious diseases - bird flu H5N1, pulmonary tuberculosis, polio, HIV / AIDS, ARI and other viral and bacterial infections.
Clinical and laboratory studies have established that «AZEOMED» has highly effective immunotropic properties, is an effective detoxifier and antioxidant, and helps to eliminate toxins from the body, including those produced by pathogenic bacteria, viruses and fungi. In addition, the drug has antiviral, antibacterial and antifungal activity and adsorbs many types of viruses and bacteria. The effectiveness of the drug in the prevention and treatment of diseases of the cardiovascular system, hypertension, diabetes and and cancer has also been established.
Based on an in-depth analysis of the many years of results of clinical and laboratory studies of the drug «AZEOMED» and its biophysical, biochemical and physiological mechanisms of exposure to the human body and viral and bacterial infections, the authors consider the use of the drug «AZEOMED» for the prevention and treatment of COVID-19 to be promising. At the end of the paper, information is given on analogues of the AZEOMED mineral complex based on natural clinoptilolite-zeolite, which are produced in various countries.
Key words: COVID-19 pandemic, «AZEOMED» mineral complex, coronavirus, viral and bacterial infection, antiviral and antibacterial activity, immunostimulant, detoxicant, antioxidant.
1. COVID-19 PANDEMIC - MODERN CHALLENGES FOR
HUMANITY AND POSSIBLE WAYS TO OVERCOME THEM
by Dr. Tamila Khalilova, Azerbaijan
The COVID-19 outbreak began in mid-December 2019 in Wuhan, Central China. Until February 19, 2020, SARS-CoV-2 infected more than 75,000 people in China and 25 more countries on five continents /1/.
Coronavirus infection has been known since 1965. Currently, more than forty types of the virus have been described; there are seven examples of overcoming the interspecific barrier between the animal world and humans. The most striking examples of this overcoming are the Middle East Respiratory Syndrome (MERS) and Severe Acute Respiratory Syndrome (SARS), first reported in China in 2002. Its subspecies is today's COVID-19. As for the current situation, the coronavirus COVID-19 behaves as a typical natural focal infection /1/.
In the framework of phytoepidemiological approaches, specific directions of virus transmission from person to person and sources for international cases of infection were identified.
The authors /1/ suggest that SARS-CoV-2 may already have been widely distributed among people in Wuhan until December 2019, probably from mid to late November. Some infected patients may have been overlooked because they had mild symptoms.
According to /2/, (as of March 28, 18:20 GTM), the number of people infected worldwide is 645.956 people, the number of deaths is 29.980 (4.6%), the number of people who have recovered 139.552 (21.7%), who were sick at the time of receiving the data 476.424 , of which moderate severity is 451.686 (95%), in critical condition 24, 738 (5%).
Figure 1: Diagram of the dynamics of patients who died and recovered in World, according to /2/.
Data for the top 10 countries by the number of patients with coronavirus are shown in Table 1. /2/.
The evolutionary history of SARS-CoV-2, studies of the distribution dynamics of COVID-19, and a complex of genomic studies are given in /1,3-7/.
We have compiled graphs showing the statistics of mortality from coronavirus depending on the age and type of chronic diseases according to the China Center for Disease Control and Prevention, Fig.2.
Figure2: Coronavirus mortality statistics in%: 1 - depending on age; 2 - depending on chronic diseases.
(These conclusions are based on 72,314 cases studied according to the /9/).
A study by Chinese scientists /8/ based on a statistical analysis of coronavirus patients in Wuhan Pulmonary Hospital and Jinyintan Hospital in Wuhan revealed very important trends and patterns of the main risk groups for Covid-19 infection. The following is table 2 given in /8/.
Studying the data in table 2 and graphs in figure 2. we understand that one of the main tasks for scientists is the development of methods and appropriate drugs that can minimize the likelihood of a decrease in immunity and the possibility of infection with coronavirus for people with a high risk of morbidity.
The categories of high mortality from coronavirus include people with concomitant diseases of the cardiovascular system (13.2%), diabetes (9.2%), hypertension (8.4%), chronic respiratory diseases (8%) and cancer patients ( 7.6%).
By age categories, old people aged ≥80 years old (maximum risk), 70-79 years old (very high risk), 60-69 years old (high risk) are at maximum risk.
Currently, many research institutes, universities and medical institutions of the world are involved in the development of an effective vaccine against COVID-19, in which leading scientists of various fields of science participate: medicine, microbiology, virology, pharmaceuticals, genetic engineering, biochemistry, biophysics and others. Scientists from China, the USA, Russia, Israel, Great Britain, France and other countries have already reported on their first successes.
Figure3:This image showing SARS-CoV-2. The spikes on the outer edge of the virus
particles resemble a crown, giving the disease its characteristic name /11/.
Table 2.Characteristics, interventions and outcomes of the study population in Wuhan Pulmonary Hospital and Jinyintan Hospital.
In figure 3. shown transmission electron microscope image shows SARS-CoV-2, the virus that causes COVID-19, isolated from a patient in the US, emerging from the surface of cells cultured in the laboratory. If we can see our enemy Covid-19, then why can't we defeat him?
In mid-March, the World Health Organization listed 41 candidate vaccines, which are being developed around the world. Meanwhile, according to the WHO, until the complete development of the coronavirus vaccine and its practical use, it will take at least one year /10/ and some experts call the period 1.5 years. If the development of the pandemic continues according to the current scenario, in one year, according to our estimates, to 2.5 million million people around the world can die.
Scientists all over the world are directly responsible because of the helplessness of modern science before the coronavirus pandemic. We, scientists from different countries, must join forces to prevent the development of the situation according to the worst-case scenario. We should not wait idly of creating a vaccine.
In addition, the vaccine can only help those who have not yet become infected with coronavirus. And what about those millions of people infected with coronavirus at the time of the creation of the vaccine, which the vaccine will not only not help but also contraindicated? How to treat them? In the process of competition between scientists and pharmaceutical companies to create a vaccine against coronavirus, millions of predicted infected people areremain defenseless against coronavirus. Maybe it makes sense to borrow the experience of China and not wait for the vaccine to appear, but use other mechanisms to combat coronavirus?
In addition to isolation and strict adherence to hygiene rules, there are other ways to significantly reduce the rate of pandemic and minimize the risk of infection for categories of people with an increased risk of infection and death from coronavirus.
Studies by Chinese scientists on the use of traditional Chinese medicine (TCM) in the prevention and treatment of coronavirus fully confirm our opinion on the high efficiency of the use of non-drugs aimed at enhancing the body's immunity and preventing the disease in people with high risk of contracting coronavirus with chronic diseases: cardio -vascular system, diabetes, respiratory tract, cancer, etc.
So, the director of the ABSL-2 laboratory at the Institute of Traditional Chinese Medicine at the Academy of Chinese Traditional Medicine, Dr. Tsui Xiaolan, said that TCM drugs improved immunity and cured many inflammatory processes and chronic diseases of patients with coronovirus and significantly reduced the risk of mortality. Yu Yanhong, secretary of the party committee of the State Administration for Traditional Chinese Medicine and Pharmacy of the People's Republic of China, said that "Clinical observation shows that traditional Chinese medicine (TCM) has proven effective in treating more than 90% of patients with confirmed COVID-19 in mainland China." /14/
