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An integrated, comprehensive survey of biomedical imaging modalities An important component of the recent expansion in bioengineering is the area of biomedical imaging. This book provides in-depth coverage of the field of biomedical imaging, with particular attention to an engineering viewpoint. Suitable as both a professional reference and as a text for a one-semester course for biomedical engineers or medical technology students, Introduction to Biomedical Imaging covers the fundamentals and applications of four primary medical imaging techniques: magnetic resonance imaging, ultrasound, nuclear medicine, and X-ray/computed tomography. Taking an accessible approach that includes any necessary mathematics and transform methods, this book provides rigorous discussions of: * The physical principles, instrumental design, data acquisition strategies, image reconstruction techniques, and clinical applications of each modality * Recent developments such as multi-slice spiral computed tomography, harmonic and sub-harmonic ultrasonic imaging, multi-slice PET scanning, and functional magnetic resonance imaging * General image characteristics such as spatial resolution and signal-to-noise, common to all of the imaging modalities
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Seitenzahl: 471
Veröffentlichungsjahr: 2017
Cover
Series
Title
Copyright
PREFACE
ACKNOWLEDGMENTS
1 X-Ray Imaging and Computed Tomography
1.1. GENERAL PRINCIPLES OF IMAGING WITH X-RAYS
1.2. X-RAY PRODUCTION
1.3. INTERACTIONS OF X-RAYS WITH TISSUE
1.4. LINEAR AND MASS ATTENUATION COEFFICIENTS OF X-RAYS IN TISSUE
1.5. INSTRUMENTATION FOR PLANAR X-RAY IMAGING
1.6. X-RAY IMAGE CHARACTERISTICS
1.7. X-RAY CONTRAST AGENTS
1.8. X-RAY IMAGING METHODS
1.9. CLINICAL APPLICATIONS OF X-RAY IMAGING
1.10. COMPUTED TOMOGRAPHY
1.11. IMAGE PROCESSING FOR COMPUTED TOMOGRAPHY
1.12. SPIRAL/HELICAL COMPUTED TOMOGRAPHY
1.13. MULTISLICE SPIRAL COMPUTED TOMOGRAPHY
1.14. RADIATION DOSE
1.15. CLINICAL APPLICATIONS OF COMPUTED TOMOGRAPHY
EXERCISES
FURTHER READING
2 Nuclear Medicine
2.1. GENERAL PRINCIPLES OF NUCLEAR MEDICINE
2.2. RADIOACTIVITY
2.3. THE PRODUCTION OF RADIONUCLIDES
2.4. TYPES OF RADIOACTIVE DECAY
2.5. THE TECHNETIUM GENERATOR
2.6. THE BIODISTRIBUTION OF TECHNETIUM-BASED AGENTS WITHIN THE BODY
2.7. INSTRUMENTATION: THE GAMMA CAMERA
2.8. IMAGE CHARACTERISTICS
2.9. SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
2.10. CLINICAL APPLICATIONS OF NUCLEAR MEDICINE
2.11. POSITRON EMISSION TOMOGRAPHY
EXERCISES
FURTHER READING
3 Ultrasonic Imaging
3.1. GENERAL PRINCIPLES OF ULTRASONIC IMAGING
3.2. WAVE PROPAGATION AND CHARACTERISTIC ACOUSTIC IMPEDANCE
3.3. WAVE REFLECTION AND REFRACTION
3.4. ENERGY LOSS MECHANISMS IN TISSUE
3.5. INSTRUMENTATION
3.6. DIAGNOSTIC SCANNING MODES
3.7. ARTIFACTS IN ULTRASONIC IMAGING
3.8. IMAGE CHARACTERISTICS
3.9. COMPOUND IMAGING
3.10. BLOOD VELOCITY MEASUREMENTS USING ULTRASOUND
3.11. ULTRASOUND CONTRAST AGENTS, HARMONIC IMAGING, AND PULSE INVERSION TECHNIQUES
3.12. SAFETY AND BIOEFFECTS IN ULTRASONIC IMAGING
3.13. CLINICAL APPLICATIONS OF ULTRASOUND
EXERCISES
FURTHER READING
4 Magnetic Resonance Imaging
4.1. GENERAL PRINCIPLES OF MAGNETIC RESONANCE IMAGING
4.2. NUCLEAR MAGNETISM
4.3. MAGNETIC RESONANCE IMAGING
4.4. INSTRUMENTATION
4.5. IMAGING SEQUENCES
4.6. IMAGE CHARACTERISTICS
4.7. MRI CONTRAST AGENTS
4.8. MAGNETIC RESONANCE ANGIOGRAPHY
4.9. DIFFUSION-WEIGHTED IMAGING
4.10.
IN VIVO
LOCALIZED SPECTROSCOPY
4.11. FUNCTIONAL MRI
4.12. CLINICAL APPLICATIONS OF MRI
EXERCISES
FURTHER READING
5 General Image Characteristics
5.1. INTRODUCTION
5.2. SPATIAL RESOLUTION
5.3. SIGNAL-TO-NOISE RATIO
5.4. CONTRAST-TO-NOISE RATIO
5.5. IMAGE FILTERING
5.6. THE RECEIVER OPERATING CURVE
Appendix A: The Fourier Transform
A.1. INTRODUCTION
A.2. FOURIER TRANSFORMATION OF TIME-DOMAIN AND SPATIAL FREQUENCY-DOMAIN SIGNALS
Appendix B: Backprojection and Filtered Backprojection
B.1. INTRODUCTION
B.2. BACKPROJECTION
B.3. FILTERED BACKPROJECTION
ABBREVIATIONS
INDEX
End User License Agreement
1 X-Ray Imaging and Computed Tomography
TABLE 1.1. The Energies of Compton-Scattered X-Rays as a Function of Scattering Angle for Various Energies of Incident X-Rays
TABLE 1.2. The Half-Value Layer (HVL) for Muscle and Bone as a Function of the Energy of the Incident X-Rays
TABLE 1.3. Effective Dose Equivalent
H
E
for Clinical X-Ray CT Exams
2 Nuclear Medicine
TABLE 2.1. Properties of Common Radionuclides Used in Nuclear Medicine
TABLE 2.2.
99
mTc Radiopharmaceuticals and Corresponding Clinical Applications
TABLE 2.3. Properties of the Most Common Radionuclides Used for PET
TABLE 2.4. Properties of Various Detectors Employed in PET
a
3 Ultrasonic Imaging
TABLE 3.1. Acoustic Properties of Biological Tissues
TABLE 3.2. Focusing Properties of Various Transducers at 1.5 and 5 MHz
4 Magnetic Resonance Imaging
TABLE 4.1. Properties of Nuclei Found at High Abudance in the Body
TABLE 4.2. Tissue Relaxation Times at 1.5 T
Cover
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