Notes on Feline Internal Medicine E-Book

Kit Sturgess

• Herausgeber: John Wiley & Sons
• Kategorie: Fachliteratur
• Serie: Notes On
• Sprache: Englisch

Seitenzahl: 721

Veröffentlichungsjahr: 2013

Beschreibung

feline internal medicine

Helping you get started with a problem-solving approach to a sick cat.

feline internal medicine

kit sturgess

Notes on Feline Internal Medicine, second edition, is part of a popular series specifically designed, through an accessible note-based style, to ensure veterinarians and students have quick and easy access to comprehensive and practical clinical and diagnostic information.

Distinct differences exist between cats and dogs not only in their physiology and metabolism but also in the way disease tends to present. This book is a short ‘pocket guide’ to feline internal medicine helping you to formulate a diagnostic plan and therapeutic strategy. The focus is on evidence-based medicine where available, otherwise current best-practice is presented.

The book is divided into five sections:

• Section 1 gives an overview of some key areas of feline medicine including paediatric and geriatric medicine.
• Section 2 focuses on the approach to common presenting signs.
• Section 3 covers the differential diagnosis of commonly used haematologic and biochemical parameters.
• Section 4 presents an organ-system based approach.
• Section 5 covers feline infectious diseases.

CHANGES FOR THIS EDITION

• Stronger focus is placed on initial testing for a disease, and what changes might be expected.
• Additional sections have been added on sedation and anaesthesia, health screening, oncology and emergency and critical care.
• More diagrams have been added to aid understanding.
• Care has been taken to avoid repetition and focus on common conditions.

Leseprobe

Contents

Cover

Notes On

Title Page

Copyright

Abbreviations

Introduction

Section 1: Key Topics in Feline Medicine

1.1 HEALTH SCREENING

1.2 PREVENTATIVE MEDICINE

1.3 PAEDIATRICS

1.4 GERONTOLOGY

1.5 SUPPORTIVE CARE – FLUID THERAPY AND ANALGESIA

1.6 SEDATION AND ANAESTHESIA

1.7 EMERGENCY AND CRITICAL CARE ALGORITHMS

Section 2: Clinical Signs

INTRODUCTION

2.1 ABDOMINAL ENLARGEMENT

2.2 ANOREXIA

2.3 ARRHYTHMIAS

2.4 ASCITES AND PERITONEAL EFFUSIONS

2.5 ATAXIA

2.6 BEHAVIOURAL CHANGES

2.7 BLEEDING/COAGULOPATHIES

2.8 BODY ODOUR

2.9 COLLAPSE, SYNCOPE AND WEAKNESS

2.10 CARDIAC MURMURS

2.11 CONSTIPATION, TENESMUS AND DYSCHEZIA

2.12 CHRONIC COUGHING

2.13 DIARRHOEA

2.14 DYSPHAGIA

2.15 DYSPNOEA (RESPIRATORY DISTRESS)

2.16 DYSURIA

2.17 FAILURE TO GROW

2.18 FLATULENCE

2.19 HAEMATEMESIS, HAEMOPTYSIS AND EPISTAXIS

2.20 HAEMATOCHEZIA AND MELAENA

2.21 HAEMATURIA AND HAEMOGLOBINURIA

2.22 HYPOTHERMIA

2.23 INCONTINENCE (URINARY)

2.24 INCONTINENCE (FAECAL)

2.25 INFERTILITY – QUEENS

2.26 INFERTILITY – TOMCATS

2.27 JAUNDICE (ICTERUS)

2.28 LYMPHADENOPATHY

2.29 OCULAR CHANGES CAUSED BY SYSTEMIC DISEASE

2.30 PALLOR

2.31 PARESIS AND PARALYSIS

2.32 POLYPHAGIA

2.33 POLYURIA/POLYDIPSIA

2.34 PTYALISM

2.35 PYREXIA (FEVER) OF UNKNOWN ORIGIN – PUO (FUO)

2.36 REGURGITATION

2.37 SEIZURES

2.38 SNEEZING AND NASAL DISCHARGE

2.39 STIFFNESS

2.40 STUPOR AND ALTERED STATES OF CONSCIOUSNESS

2.41 TREMOR

2.42 VOMITING

2.43 WEIGHT LOSS

Section 3: Common Abnormalities of Haematology, Biochemistry and Urinalysis

INTRODUCTION

3.1 LOW HAEMATOCRIT

3.2 HIGH HAEMATOCRIT

3.3 PLATELET ABNORMALITIES AND CLOTTING SYSTEM

3.4 WHITE BLOOD CELL CHANGES

3.5 ACID–BASE DISTURBANCES

3.6 AMYLASE AND LIPASE

3.7 AZOTAEMIA

3.8 CALCIUM IMBALANCE

3.9 CHOLESTEROL AND TRIGLYCERIDE CHANGES

3.10 ELECTROLYTE DISTURBANCES

3.11 GLUCOSE ABNORMALITIES

3.12 LIVER PARAMETERS

3.13 MUSCLE ENZYMES

3.14 PHOSPHATE

3.15 PROTEIN ABNORMALITIES

3.16 URINALYSIS

Section 4: Organ Systems

4.1 RESPIRATORY DISEASE

4.2 CARDIOLOGY

4.3 GASTROINTESTINAL TRACT (GIT) DISEASE

4.4 HEPATOBILIARY DISEASE

4.5 RENAL DISEASE

4.6 LOWER URINARY TRACT DISEASE

4.7 ENDOCRINE DISEASE

4.8 NEUROLOGIC DISEASE

4.9 NEUROMUSCULAR AND MUSCULAR DISEASE

4.10 SKELETAL DISEASE

4.11 DISORDERS OF THE BLOOD, HAEMOPOIETIC AND IMMUNE SYSTEM

4.12 ONCOLOGY AND CHEMOTHERAPY

4.13 NUTRITION

4.14 INTOXICATION

Section 5: Infectious Disease

5.1 BORDETELLOSIS

5.2 VIRAL UPPER RESPIRATORY TRACT DISEASE

5.3 AVIAN INFLUENZA

5.4 CHLAMYDOPHILA FELIS

5.5 FELINE INFECTIOUS ANAEMIA

5.6 FELINE INFECTIOUS PERITONITIS

5.7 FELINE SPONGIFORM ENCEPHALOPATHY

5.8 MYCOBACTERIAL INFECTIONS

5.9 RABIES VIRUS

5.10 TOXOPLASMOSIS

5.11 FELINE LEUKAEMIA VIRUS

5.12 FELINE IMMUNODEFICIENCY VIRUS

5.13 FELINE VIRAL ENTERITIS

5.14 OTHER INFECTIOUS DISEASE

5.15 FELINE ZOONOSES

Further reading

Index

Notes On

“Notes on” is an exciting series specifically designed, through an accessible note-based style, to ensure veterinarians and students have quick and easy access to the most up-to-date clinical and diagnostic information.

Other titles in the series:

Canine Internal Medicine, third edition Edward J. Hall, Kate Murphy and Peter G. Darke 9780632053711

Rabbit Internal MedicineRichard Saunders and Ron Rees Davies 9781405115148

Small Animal DermatologyJudith Joyce 9781405134972

Cardiorespiratory Diseases of the Dog and Cat, second edition Mike Martin and Brendan Corcoran 9781405122641

This edition first published 2013 © 2003, 2013 by John Wiley & Sons, Ltd

Registered office: John Wiley & Sons, Ltd, The Atrium, Southern Gate, Chichester, West Sussex, PO19 8SQ, UK

Editorial offices: 9600 Garsington Road, Oxford, OX4 2DQ, UK The Atrium, Southern Gate, Chichester, West Sussex, PO19 8SQ, UK 1606 Golden Aspen Drive, Suites 103 and 104, Ames, Iowa 50010, USA

For details of our global editorial offices, for customer services and for information about how to apply for permission to reuse the copyright material in this book please see our website at www.wiley.com/wiley-blackwell

The right of the author to be identified as the author of this work has been asserted in accordance with the UK Copyright, Designs and Patents Act 1988.

All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, except as permitted by the UK Copyright, Designs and Patents Act 1988, without the prior permission of the publisher.

Designations used by companies to distinguish their products are often claimed as trademarks. All brand names and product names used in this book are trade names, service marks, trademarks or registered trademarks of their respective owners. The publisher is not associated with any product or vendor mentioned in this book. It is sold on the understanding that the publisher is not engaged in rendering professional services. If professional advice or other expert assistance is required, the services of a competent professional should be sought.

The contents of this work are intended to further general scientific research, understanding, and discussion only and are not intended and should not be relied upon as recommending or promoting a specific method, diagnosis, or treatment by health science practitioners for any particular patient. The publisher and the author make no representations or warranties with respect to the accuracy or completeness of the contents of this work and specifically disclaim all warranties, including without limitation any implied warranties of fitness for a particular purpose. In view of ongoing research, equipment modifications, changes in governmental regulations, and the constant flow of information relating to the use of medicines, equipment, and devices, the reader is urged to review and evaluate the information provided in the package insert or instructions for each medicine, equipment, or device for, among other things, any changes in the instructions or indication of usage and for added warnings and precautions. Readers should consult with a specialist where appropriate. The fact that an organization or Website is referred to in this work as a citation and/or a potential source of further information does not mean that the author or the publisher endorses the information the organization or Website may provide or recommendations it may make. Further, readers should be aware that Internet Websites listed in this work may have changed or disappeared between when this work was written and when it is read. No warranty may be created or extended by any promotional statements for this work. Neither the publisher nor the author shall be liable for any damages arising herefrom.

Library of Congress Cataloging-in-Publication DataSturgess, Kit.  Notes on feline internal medicine / Kit Sturgess. – 2nd ed.   p.; cm.  Includes bibliographical references and index.   ISBN 978-0-470-67117-7 (pbk.) – ISBN 978-1-118-59769-9 (Mobi) – ISBN 978-1-118-59771-2 (ePDF) – ISBN 978-1-118-59772-9 (ePub) – ISBN 978-1-118-64516-1 – ISBN 978-1-118-64536-9  I. Title.  [DNLM: 1. Cat Diseases–diagnosis–Handbooks. 2. Cat Diseases–therapy–Handbooks. SF 985]  SF985  636.8089–dc23

2013013320

A catalogue record for this book is available from the British Library.

Wiley also publishes its books in a variety of electronic formats. Some content that appears in print may not be available in electronic books.

Cover image (left): Photo by Kit Sturgess; (middle) iStock stock-photo-15408185-cats-x-ray; (right) stock-photo-18813080-veterinarian

Cover design by Sandra Heath

ABBREVIATIONS

⇒

implies

%

percent

/

per

@

at

<

less than

>

greater than

±

with or without

2D

two dimensional

AAFP

American association of feline practitioners

AcCh

acetylcholine

ACE

angiotensin-converting enzyme

ACEi

angiotensin-converting enzyme inhibitor

ACP

acepromazine

ACT

activated clotting time

ACTH

adrenocorticotropic hormone

ADE

antibody-dependent enhancement

ADH

antidiuretic hormone (vasopressin)

ad lib

free access

AF

atrial fibrillation

A:G

albumin to globulin (ratio)

AIDS

acquired immunodeficiency syndrome

AKI

acute kidney injury

ALI

acute lung injury

AL(K)P

alkaline phosphatase

ALT

alanine aminotransferase

ANA

antinuclear antibody

Ao

aorta

APC

atrial premature contraction

APTT

activated partial thromboplastin time

APUDomas

amine precursor and uptake decarboxylation omas

ARDS

acute respiratory distress syndrome

ASA

American society of anesthesiologists

ASD

atrial septal defect

AST

aspartate aminotransferase

ATIII

antithrombin III

AV

arteriovenous; atrioventricular

AZT

azidothymidine

B12

vitamin B12

BA

bile acids

BCS

body condition score

BE

base excess

BIPS

barium impregnated polyspheres

BMR

basal metabolic rate

BNP

brain natriuretic peptide

BP

blood pressure

bpm

beats per minute

BSA

body surface area

BSH

British shorthair

C

cervical vertebra (followed by number)

C.

Clostridium

Ca2+

calcium ion

cAMP

cyclic adenosine monophosphate

C(P)K

creatine (phospho)kinase

CD

cluster of differentiation (followed by number)

CDI

central diabetes insipidus

cf.

compare with

CHF

congestive heart failure

CKD

chronic kidney disease

Cl-

chloride ion

CN

cranial nerve

CNS

central nervous system

CO

cardiac output

CO2

carbon dioxide

COAP

cyclophosphamide, Oncovin (vincristine), L-asparaginase prednisolone

COP

cyclophosphamide, Oncovin (vincristine), prednisolone; colloidal osmotic pressure

COX

cyclooxygenase

CPCR

cardiopulmonary cerebral resuscitation

CPV(2)

canine parvovirus (2)

CRI

continuous rate infusion

CSF

cerebrospinal fluid

CT

computed tomography

cTnI

cardiac troponin I

CVA

cerebrovascular accident

CVP

central venous pressure

D

right (isomer)

DCM

dilated cardiomyopathy

DDAVP

desmopressin

DEET

DI

diabetes insipidus

DIC

disseminated intravascular coagulation

DKA

diabetic ketoacidosis

dl

decilitre

DLH

domestic long hair

DM

diabetes mellitus

DMSO

dimethylsulfoxide

DNA

deoxyribonucleic acid

DSH

domestic short hair

DV

dorsoventral

e.g.

for example

ECG

electrocardiogram

EDTA

ethylenediaminetetraacetic acid

EFA

essential fatty acid

ELISA

enzyme-linked immunosorbent assay

EM

electron microscopy

EMG

electromyelogram

ENT

ear, nose, throat

EPI

exocrine pancreatic insufficiency

EPO

erythropoietin

ET

endotracheal

ETCO2

end-tidal carbon dioxide

F

female; factor

FAIDS

feline AIDS

FB

foreign body

FCoV

feline coronavirus

FCV

feline calicivirus

FDP

fibrin(ogen) degradation product

FE

fractional excretion

FeLV

feline leukaemia virus

FeSFV

feline syncytium-forming virus

FG

French gauge

FHV-1

feline herpesvirus 1

FIA

feline infectious anaemia

FIC

feline idiopathic cystitis

FIP

feline infectious peritonitis

FIV

feline immunodeficiency virus

fl

femtolitre

FLK

fentanyl, lidocaine and ketamine

FLUTD

feline lower urinary tract disease

FNA

fine needle aspirate

FOCMA

feline oncornavirus cell-membrane-associated antigen

FORL

feline odontoclastic resorptive lesion

FPV

feline parvovirus

fPLi

feline pancreatic-specific lipase

Fr

French

FS

fractional shortening

FSE

feline spongiform encephalopathy

fTLI

feline trypsin-like immunoreactivity

fTSH

feline TSH

g

gram; gauge

GA

general anaesthesia

GAG

glycosaminoglycans

GFR

glomerular filtration rate

GI

gastrointestinal

GIT

gastrointestinal tract

GME

granulomatous meningoencephalitis

gp

glycoprotein followed by number (= molecular weight × 1000 in daltons)

GT

glutamyl transferase

h

hour

H+

hydrogen ions

H2

type 2 histamine receptor

HAC

hyperadrenocorticism

Hb

haemoglobin

HCM

hypertrophic cardiomyopathy

HCO3−

bicarbonate ions

HCT

haematocrit

Hg

mercury

HGAL

high grade alimentary lymphoma

HIV

human immunodeficiency virus

hpf

high power field

I

ionised

i.e.

that is

I131

radioactive iodine

IBD

inflammatory bowel disease

IC

immunochromatography

iCa2+

ionised calcium

ICP

intracranial pressure

IF

immunofluorescence

IFA

immunofluorescent antibody

iFLUTD

idiopathic feline lower urinary tract disease

Ig

immunoglobulin

IgA

immunoglobulin A

IGF-1

insulin-like growth factor 1

IgG

immunoglobulin G

IgM

immunoglobulin M

iIBD

idiopathic IBD

IM

intramuscular

IMHA

immune-mediated haemolytic anaemia

IRIS

International renal interest society

iU

international units

IV (i/v)

intravenous

IVFT

intravenous fluid therapy

IVS

interventricular septum

JGA

juxtaglomerular apparatus

K+

potassium ion

kcal

kilocalories

KCl

potassium chloride

kg

kilogram

l

litre

L

lumbar vertebra (followed by number)

L

lumbar vertebra (followed by number); left

LA

left atrium

LAFB

left anterior fascicular block

LAP

left atrial pressure

LBBB

left bundle branch block

LDH

lactate dehydrogenase

LGAL

low grade alimentary lymphoma

LMN

lower motor neuron

LUTD

lower urinary tract disease

LV

left ventricular

LVOT

left ventricular outflow tract

m

metres

M

male

M.

Mycoplasma; Mycobacterium

MCH

mean cell haemoglobin

MCHC

mean cell haemoglobin concentration

MCV

mean cell volume

MDA

maternally derived antibody

ME

metabolisable energy

MEA

mean electrical axis

MEN

multiple endocrine neoplasia

mEq

milliequivalent

MER

maintenance energy requirement

mg

milligram

Mg2+

magnesium ion

MHz

mega hertz

min

minute

ml

millilitre

MLK

morphine, lidocaine and ketamine

mmol

millimoles

MODS

multiple organ dysfunction syndrome

MRI

magnetic resonance imaging

MV

mitral valve

MVO2

myocardial oxygen consumption

MVO2

myocardial oxygen demand

MW

molecular weight

n

number (in sequence of carbon atoms)

Na+

sodium ion

NA (N/A)

not assessed

NaCl

salt (sodium chloride)

NB

nota bene

NDI

nephrogenic diabetes insipidus

ng

nanograms

NH4Cl

ammonium chloride

NMDA

N-methyl-D-asparate

nmol

nanomoles

NSAIDs

non-steroidal anti-inflammatory drugs

NT-proBNP

N-terminal pro brain natriuretic peptide

°C

degrees Celsius

°F

degrees Fahrenheit

OP

organophosphate

OSPT

one stage prothrombin time

p

protein followed by number (= molecular weight × 1000 in daltons)

PA

pulmonary artery

pCO2

partial pressure of carbon dioxide

PCR

polymerase chain reaction

PCV

packed cell volume

PD

polydipsia

PDA

persistent ductus arteriosus

PE

Pericardial effusion

PEG

percutaneous endoscopic gastrostomy

PETS

pet travel scheme

pg

picograms

pH

acid-base balance of a substance

PHA

primary hyperaldosteronism

PIVKAs

proteins induced by vitamin K antagonists

PKD

polycystic kidney disease

PLE

protein losing enteropathy

PLR

pupillary light response

PM

post mortem

PMEA

phosphonomethoxyethyl adenine

PMI

point of maximum intensity

pmol

picomoles

PNS

peripheral nervous system

PO

per os

pO2

partial pressure of oxygen

POM-V

prescription only medicine – veterinary

PPDH

pericardioperitoneal diaphragmatic hernia

proBNP

pro brain natriuretic peptide

PSS

portosystemic shunt

PT

prothrombin

PTH

parathyroid hormone

PTH-rP

parathyroid hormone-related peptide

PU

polyuria

PU/PD

polyuria/polydipsia

PUFA

polyunsaturated fatty acid

PUO

pyrexia of unknown origin

PVC

polyvinyl chloride

q

every

qPCR

real time PCR

RA

right atrium

RAAS

renin–angiotensin–aldosterone system

RBBB

right bundle branch block

RBCC

red blood cell count

RBC

red blood cell

RCM

restricted cardiomyopathy

RER

resting energy requirement

RIM

rapid immunodiffusion

R→L

right to left

RNA

ribonucleic acid

RR

respiratory rate

R-R

time interval between successive R waves on an ECG

RTA

road traffic accident

S

heart sound (followed by number); sacral vertebra (followed by number)

SA

sinoatrial

SAMe

s-adenosyl methionine

SAM

systolic anterior motion

SAP

serum alkaline phosphatase

SC

subcutaneous

SCC

squamous cell carcinoma

SG

specific gravity

SIRS

systemic inflammatory response syndrome

SLE

systemic lupus erythematosus

sp(p).

species

SpO2

oxygen saturation measured by pulse oximetry

T

thoracic vertebra (followed by number); total

T3

triiodothyronine

T4

thyroxin; fourth thoracic vertebra

TCO2

total carbon dioxide

TLI

trypsin-like immunoreactivity

TMJ

temporomandibular joint

TOC

treatment of choice

TP

total protein

TPR

temperature, pulse and respiration

TRH

thyroid stimulating releasing hormone

TSH

thyroid stimulating hormone

TV

tricuspid valve

U

international units

U

units

UCCR

urine cortisol:creatinine ratio

UGA

under general anaesthesia

UK

United Kingdom

UMN

upper motor neuron

UPC (R)

urine protein:creatinine ratio

URT

upper respiratory tract

URTD

upper respiratory tract disease

USA

United States of America

USG

urine specific gravity

USMI

urethral sphincter mechanism incompetence

UTI

urinary tract infection

UV

ultraviolet

VCTM

viral chlamydia transport medium

VD

ventrodorsal

VI

virus isolation

VPC

ventricular premature contraction

VSD

ventricular septal defect

vs.

versus

VWF

von Willebrand factor

WBC

white blood cell

WBCC

white blood cell count

WHO

world health organisation

WSAVA

World small animal veterinary association

XO

female with single X chromosome

μmol

micromoles

γ-GT; GGT

gamma glutamyl transferase

μg

microgram

μl

microlitre

INTRODUCTION

Since the first edition of this book in 2003, feline medicine has continued to expand rapidly. It is estimated that there are between 9.3 and 11.3 million pet cats and a similar number of pet dogs in the United Kingdom. The increase in pet cat numbers seems to be a worldwide trend. Many practices, particularly those in towns and cities, see more cats than dogs for consultations. Ninety two percent of the pet cats in the United Kingdom are domestic short hairs (moggies) compared to the dog population that is 75% pedigree. Cats are more likely to be kept as pets for companionship than dogs because they are perceived as being easier to look after and as fitting better with current lifestyles; this may explain the increases that are being seen in the pet cat population.

Throughout this book, focus will be placed on evidence-based medicine. Where this is unavailable, current best practice will be presented. Additional sections have been provided on sedation and anaesthesia, health screening, oncology and emergency and critical care. The number of diagrams has been increased and sources of further information highlighted.

Fewer drugs are licensed for use in cats than dogs, so the dose rates of many compounds used off-label are based on clinical experience and may require modification as appropriate. When deciding upon which drug to use, it is important to remember that the cascade system (in the United Kingdom) applies to the choices made.

The text is divided into five sections:

Section 1 gives an overview of other key areas of feline medicine including health screening, paediatric and geriatric medicine, analgesia, fluid therapy, anaesthesia and algorithms for emergency and critical care.Section 2 focuses on the approach to common presenting signs.Section 3 covers the differential diagnosis of commonly used haematologic and biochemical parameters.Section 4 presents an organ-system-based approach.Section 5 covers feline infectious diseases.

Distinct differences exist between cats and dogs not only in their physiology and metabolism but also in the way disease tends to present. Sick cats tend to mask the nature and extent of their disease, becoming withdrawn and quiet; as a consequence, presentation to a veterinarian is often later in the course of the disease. Cats also seem to be more ‘secretive' about their clinical signs, and are less likely to have organ-specific presentations, tending to show lethargy and inappetence instead.Owners are also changing, becoming more informed and demanding of a diagnosis, making problem-based medicine central to the approach to a sick cat.

This text is intended to be a short ‘pocket guide' to feline internal medicine, aimed at assisting in the formulation of a diagnostic plan and therapeutic strategy. References will not be given in the text, but a selection of useful texts and websites will be included at the end.

Physical examination

A calm approach, and in the majority of cases minimal restraint, usually allows thorough clinical evaluation (see http://catvets.com/professionals/guidelines/publications/index.aspx?Id=468 for the American Association of Feline Practitioners and International Society of Feline Medicine guide on cat handling 2011). Some cats, however, require chemical restraint in order for a thorough physical examination to be performed – see section 1.6. A systematic examination is mandatory to ensure that no major problems are overlooked. As inappetence is a major presentation in cats, oral examination should always be performed. In cats over 6 years of age, palpation of the ventral neck for a goitre should also become part of the regime. Enlarged thyroid glands can be best palpated with the cat standing and the chin raised; the trachea is located between the thumb and first finger and the neck is palpated craniocaudally. If no gland is felt, and the cat is amenable, the cat can be gently tipped head downwards, allowing a thyroid nodule that is lying just within the thoracic inlet to be palpated.

Auscultation of the cardiorespiratory system can be optimised by using a paediatric, infant or electronic stethoscope that will allow better localisation of any abnormality. The upper and lower respiratory tracts, including the trachea, should be included to determine whether increased parenchymal lung sounds are, in fact, referred from the upper airway. Cardiac murmurs are frequently loudest parasternally and relatively cranially in cats, making them easy to miss if auscultation is carried out only at the left apex. Purring can prevent adequate thoracic auscultation and is difficult to stop. Sometimes turning on a tap, gentle compression of the larynx, covering the nares or blowing on the nostrils will work, but these are not always practical or effective solutions. Thoracic examination should include percussion as well as palpation of the cranial thorax for compressibility. Cats' chests tend to sound relatively resonant even when fluid is present; it is therefore important to percuss all cats so the subtle lowering of pitch and slight loss of resonance that accompany a pleural effusion can be appreciated.

Abdominal palpation is rewarding in most cats. Both kidneys, the small and large intestines and the bladder can be appreciated in non-obese, normal cats. The stomach, liver and spleen are not usually palpated unless abnormal. Lifting the cat's forelimbs can sometimes aid renal palpation.

Assessing the locomotor system is difficult, as many cats are reluctant to walk in the consulting room. In cases where such an evaluation is important, owner history is crucial and video evidence can also be helpful.

Clinical pathology

Haematology

Many automated machines struggle to produce accurate results due to the relatively spherical nature of feline red cells and the tendency for platelets to clump. Whilst the automated result can provide valuable information, examination of a smear is essential if more than a packed cell volume is required. A smear should always be included when blood is sent to an external laboratory for evaluation.

Interpretation

See Section 3 (Laboratory Abnormalities).

Biochemistry

In the text, routine biochemistry refers to:

Total protein, albumin and globulinAlanine aminotransferase (ALT) and alkaline phosphatase (ALP)Urea and creatinineCholesterolCalcium and phosphorusElectrolytes (sodium, potassium ± chloride)Creatine kinase (CPK)

The value of estimating lipase and amylase is limited in cats and does not form part of a routine biochemical evaluation.

Radiology and Ultrasound

Cats make good subjects for radiography, as they are small and of relatively even body thickness. The use of a grid in cats is unnecessary. Detail can be improved by using a suitable film–screen combination. Sedation or anaesthesia is required in all but the sickest of cats.

Ultrasound can be very rewarding in cats, relatively high frequency probes are required. A 7.5mHz microconvex or 10mHz linear probe are ideal producing high quality images and allowing the internal structure of the abdominal organs to be examined.

Sedation

Sedation is frequently necessary during the investigation of a sick cat. A variety of drug combinations have been recommended (see Section 1.6).

Notes on Feline Internal Medicine, Second Edition. Edited by Kit Sturgess. ©2013 John Wiley & Sons, Ltd. Published 2013 by Blackwell Publishing Ltd.