Platelet Rich Fibrin in Regenerative Dentistry E-Book

• Herausgeber: John Wiley & Sons
• Kategorie: Fachliteratur
• Sprache: Englisch

Seitenzahl: 511

Veröffentlichungsjahr: 2017

Beschreibung

The first book devoted exclusively to the subject, Platelet Rich Fibrin in Regenerative Dentistry offers comprehensive, evidence-based coverage of the biological basis and clinical applications of PRF in dentistry. Co-edited by a leading researcher in tissue regeneration and the inventor of the PRF technique, it brings together original contributions from expert international researchers and clinicians. Chapters cover the biological foundation of PRF before addressing specific uses of the technology within clinical dentistry. Topics describe the use of PRF in many dental applications, including extraction socket management, sinus lifting procedures, root coverage, periodontal regeneration, soft tissue healing around implants, guided bone regeneration, and facial esthetics. The text is supplemented with color photographs and explanatory illustrations throughout. Platelet Rich Fibrin in Regenerative Dentistry: Biological Background and Clinical Indications is an indispensable professional resource for periodontists, oral surgeons and oral and maxillofacial surgeons, as well as general dentists who use PRF or are interested in introducing it into their practices. It is also an excellent reference for undergraduate and postgraduate dental students.

Leseprobe

Platelet Rich Fibrin in Regenerative Dentistry

Biological Background and Clinical Indications

Edited by

Richard J. Miron, Dr. med. dent., DDS, BMSC, MSc, PhD

Department of Periodontology College of Dental Medicine Nova Southeastern University Fort Lauderdale, Florida, USA

Joseph Choukroun, MD

Private practice, Pain Therapy Center Nice, France

This edition first published 2017© 2017 John Wiley & Sons Ltd

All rights reserved. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, except as permitted by law. Advice on how to obtain permission to reuse material from this title is available at http://www.wiley.com/go/permissions.

The right of Richard J. Miron and Joseph Choukroun to be identified as the authors of the editorial material in this work has been asserted in accordance with law.

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Library of Congress Cataloging-in-Publication Data

Names: Miron, Richard J. (Richard John), 1983– editor. | Choukroun, Joseph, 1952– editor.Title: Platelet rich fibrin in regenerative dentistry : biological background and clinical indications / edited by Richard J. Miron, Joseph Choukroun.Description: Hoboken, NJ : Wiley, 2017. | Includes bibliographical references and index. |Identifiers: LCCN 2017017750 (print) | LCCN 2017018765 (ebook) | ISBN 9781119406891 (pdf) | ISBN 9781119406808 (epub) | ISBN 9781119406815 (cloth)Subjects: | MESH: Oral Surgical Procedures | Fibrin--therapeutic use | Platelet-Rich Plasma | Tissue Engineering | Bone RegenerationClassification: LCC RK307 (ebook) | LCC RK307 (print) | NLM WU 600 | DDC 617.522--dc23LC record available at https://lccn.loc.gov/2017017750

Cover Design: WileyCover Images: (Foreground, PRF clot & instruments) Courtesy of Jonathan Du Toit; (Background, centrifuge image) Courtesy of Joseph Choukroun

To my parents, family, and friends who have all sacrificed far too often in my pursuit of a career in academic dentistry

To my classmates, colleagues, and mentors who constantly raised the bar and strived for better

To the team at Advanced PRF Education who made excellence in teaching a top priority

In gratitude to my Mentors and Professors at the University of Montpellier and Strasbourg, France. Your education and mentorship has given me the means to innovate in the treatment of pain and wound healing.

Contents

About the Authors

Foreword

Preface

1 Platelet Rich Fibrin: A Second-Generation Platelet Concentrate

1.1 Introduction

1.2 Brief history of platelet concentrates

1.3 The development of PRF from PRP

1.4 Effect of PRF on periosteum behavior

1.5 The first case treated with PRF

1.6 Conclusion

References

2 Biological Components of Platelet Rich Fibrin: Growth Factor Release and Cellular Activity

2.1 Introduction

2.2 Cell components of PRF

2.3 Advantages of a three-dimensional fibrin network

2.4 Growth factors in blood

2.5 PRP versus PRF for growth factor release

2.6 L-PRF versus A-PRF vs A-PRF+—new findings with the low-speed centrifugation concept and low-time induces even higher growth factor release

2.7 i-PRF versus PRP—growth factor release

2.8 Cell behavior in response to L-PRF, A-PRF, and A-PRF+

2.9 Cell behavior in response to PRP, i-PRF

2.10 Future prospective

References

3 Introducing the Low-Speed Centrifugation Concept

3.1 Introduction

3.2 Development of advanced solid PRF matrices following the low speed centrifugation concept (LSCC)

3.3 Development of an injectable PRF (i-PRF) following the low speed centrifugation concept (LSCC)

3.4 Platelets and leukocytes are key elements in the regeneration process

3.5 Clinical insights

3.6 Conclusion

References

4 Uses of Platelet Rich Fibrin in Regenerative Dentistry: An Overview

4.1 Introduction

4.2 Extraction socket management with PRF

4.3 Sinus elevations procedures with PRF

4.4 Use of PRF for soft-tissue root coverage

4.5 Use of PRF for periodontal regeneration

4.6 Use of PRF for the regeneration of soft tissues around implants

4.7 Use of PRF in guided bone regeneration

4.8 Use of PRF in various other aspects of dentistry and medicine

4.9 Conclusion

References

5 Use of Platelet Rich Fibrin for the Management of Extraction Sockets: Biological Basis and Clinical Relevance

5.1 Introduction

5.2 Natural dimensional changes occurring post-extraction

5.3 Conventional socket grafting and ridge preservation techniques

5.4 Immediate implant placement into fresh extraction sockets

5.5 Overview of utilizing PRF in extraction sockets

5.6 Discussion and future research

References

6 Maxillary Sinus Floor Elevation in the Atrophic Posterior Maxillae: Anatomy, Principles, Techniques, Outcomes, and Complications

6.1 Introduction

6.2 Anatomical considerations

6.3 Biological principles

6.4 Surgical techniques

6.5 Clinical outcomes

6.6 Surgical and post-surgical complications

6.7 Conclusion

References

7 Maxillary Sinus Floor Elevation Procedures with Platelet Rich Fibrin: Indications and Clinical Recommendations

7.1 Introduction

7.2 PRF as a sole grafting material during sinus lifting procedures

7.3 PRF for the repair of Schneiderian membranes

7.4 PRF for the closure of the lateral maxillary access window

7.5 Discussion and future outlook

References

8 Use of Platelet Rich Fibrin for the Treatment of Muco-Gingival Recessions: Novel Improvements in Plastic Aesthetic Surgery Utilizing The Fibrin Assisted Soft Tissue Promotion (FASTP) Technique

8.1 Introduction

8.2 Plastic periodontal procedures with PRF

8.3 Fibro promotion: the basic mechanism of Fibrin-Assisted Soft Tissue Promotion (FASTP) technique

8.4 FASTP: the surgical technique

8.5 Conclusion

References

9 Use of Platelet Rich Fibrin for Periodontal Regeneration/Repair of Intrabony and Furcation Defects

9.1 Introduction

9.2 Role of barrier membranes in periodontal regeneration

9.3 Role of bone-grafting materials in periodontal regeneration

9.4 Biologic agents/growth factors for periodontal regeneration

9.5 Platelet rich fibrin (PRF) as a potential autologous biological agent for periodontal regeneration

9.6 Intrabony defect regeneration with PRF: results from controlled clinical trials

9.7 Furcation defect regeneration with PRF

9.8 Discussion and future research

References

10 Platelet Rich Fibrin as an Adjunct to Implant Dentistry

10.1 Introduction

10.2 PRF treatment of peri-implant defects

10.3 PRF and soft-tissue healing at implants

10.4 Osseointegration

10.5 Techniques to improve primary stability in poor bone quality

10.6 The use of PRF at osteotomy preparation

10.7 The future of PRF and implants

References

11 Guided Bone Regeneration with Platelet Rich Fibrin

11.1 Introduction

11.2 Overview of GBR

11.3 Available options of GBR

11.4 Non-resorbable PTFE membranes

11.5 Titanium mesh

11.6 Collagen-based resorbable membranes

11.7 Synthetic resorbable membranes

11.8 Plasma-rich proteins as growth factors for membranes

11.9 Choice of bone-grafting materials during GBR procedures

11.10 Alternative strategies to induce new bone formation during GBR procedures

11.11 Recent surgical approaches using PRF in combination with GBR

11.12 PRF as a barrier membrane in GBR procedures

11.13 PRF in combination with bone-grafting materials

11.14 Studies investigating PRF for GBR

11.15 Discussion and future research

References

12 Modern Approach to Full Arch Immediate Loading: The Simonpieri Technique with PRF and i-PRF

12.1 Introduction

12.2 Immediate loading in implant dentistry—what is success?

12.3 Biological requirements

12.4 Anatomical and surgical requirements

12.5 Prosthetic requirements

12.6 Final results

12.7 Documented long-term stability

12.8 Long-term statistical results: full arch immediate implant placement and loading

12.9 Conclusion

References

13 Use of Platelet Rich Fibrin in Facial Aesthetics and Rejuvenation

13.1 Introduction

13.2 Features of the skin

13.3 Aging and the epidermal barrier function mechanisms in skin aesthetics

13.4 Pre-evaluation and patient selection

13.5 Conventional therapies in facial aesthetics

13.6 Lasers and epidermal barrier function

13.7 Overview of utilizing platelet derivatives in facial aesthetics

13.8 Clinical procedures utilizing PRF in facial aesthetics

13.9 i-PRF injections with a derma rollers

13.10 i-PRF injections with a derma pen

13.11 i-PRF and PRF for mesotherapy by syringe injections

13.12 Platelet concentrate during the vampire technique

13.13 Augmentation techniques with PRF matrix and i-PRF—combination Therapies

13.14 Nasolabial fold rejuvenation with PRF and i-PRF

13.15 Use of PRF and i-PRF for lip augmentation

13.16 PDO threads using PRF and i-PRF

13.17 Conclusion

References

14 Use of Platelet Rich Fibrin in Other Areas of Medicine

14.1 Introduction

14.2 Effects of PRF on cell activity in vitro

14.3 Evidence that PRF improves soft-tissue wound healing/regeneration in vivo

14.4 Clinical studies evaluating the use of PRF in medicine

14.5 PRF for regeneration of chronic leg ulcers

14.6 PRF for cartilage (knee) regeneration

14.7 PRF for the regeneration of ligaments and tendons

14.8 PRF in orthopedic medicine

14.9 PRF for skin regeneration

14.10 Discussion and future perspectives

References

15 Future Research with Platelet Rich Fibrin

15.1 PRF and centrifugation speeds

15.2 Effect of hematocrit count on PRF scaffolds

15.3 The influence of PRF for the treatment of osteonecrosis of the jaw

15.4 Injectable platelet rich fibrin as a potential therapy for temporomandibular joint disorders

15.5 Potential use of platelet rich fibrin for pulp regeneration

15.6 Platelet rich fibrin and periodontal regeneration

15.7 Potential use of stem cells derived from blood

15.8 PRF: regeneration by growth factors, leukocytes, or fibrin?

15.9 PRF and its degradation properties

15.10 PRF and osteoinduction

References

Index

EULA

List of Tables

Chapter 1

Table 1.1

Chapter 5

Table 5.1

Chapter 6

Table 6.1

Chapter 7

Table 7.1

Chapter 8

Table 8.1

Table 8.2

Chapter 9

Table 9.1

Table 9.2

Chapter 11

Table 11.1

Table 11.2

Table 11.3

Guide

Cover

Table of Contents

Preface

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