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PEATE'S BODY SYSTEMS
THE ENDOCRINE SYSTEM
A CONCISE, ILLUSTRATED, AND ACCESSIBLE GUIDE TO THE ENDOCRINE SYSTEM
Each of the twelve volumes in Peate’s Body Systems series is rooted in the belief that a deep and thorough understanding of the human body is essential for providing the highest standard of care. Offering clear, accessible and up-to-date information on different body systems, this series bridges the gap between complex scientific concepts and practical, everyday applications in health and care settings. This series makes for an invaluable resource for those committed to understanding the intricacies of human biology, physiology and the various systems that sustain life.
The Endocrine System is the perfect companion for students and newly registered practitioners across nursing and allied health fields with an interest in endocrinology, providing a comprehensive yet easy-to-digest guide for both academic and clinical application.
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Seitenzahl: 311
Veröffentlichungsjahr: 2025
Cover
Table of Contents
Title Page
Copyright
Preface
Acknowledgements
Chapter 1 Anatomy and Physiology: The Endocrine System
Homeostasis
The Endocrine Organs
Endocrine, Paracrine, Exocrine and Autocrine Signalling
Hormones
The Transportation of Hormones
Control of Hormone Release
The Physiology of the Endocrine Organs
The Hypothalamus and the Pituitary Gland
Growth Hormone
Prolactin
Follicle‐Stimulating Hormone and Luteinising Hormone (Gonadotrophins)
Thyroid‐Stimulating Hormone
Adrenocorticotrophic Hormone
The Thyroid Gland
Parathyroid Glands
The Adrenal Glands
The Pancreas
The Gonads
Other Endocrine Glands
Conclusion
Glossary of Terms
Multiple Choice Questions
References
Chapter 2 Assessment of the Endocrine System
Assessing Needs
The Patient History
Empathy
A Focused Endocrine Assessment
Assessing the Thyroid Gland
Conclusion
Glossary of Terms
Multiple Choice Questions
References
Chapter 3 Hyperthyroidism
The Thyroid Gland
Thyroxine and Triiodothyronine
Pathophysiological Changes Associated with Hyperthyroidism
Epidemiology
Risk Factors
Clinical Presentation
Clinical Investigations and Diagnosis
Management
Health Teaching
Understanding Hyperthyroidism
Treatment Options
Long-term Management and Follow-up
Conclusion
Glossary of Terms
Multiple Choice Questions
References
Chapter 4 Hypothyroidism
Total Thyroxine and Free Thyroxine
Pathophysiological Changes Associated with Hypothyroidism
Myxoedema
Primary and Secondary Hypothyroidism
Epidemiology
Risk Factors
Clinical Presentation
Clinical Investigations and Diagnosis
Management
Health Teaching
Conclusion
Glossary of Terms
Multiple Choice Questions
References
Chapter 5 Diabetes Mellitus
Type 1 Diabetes
Type 2 Diabetes
Gestational Diabetes
Diabetes Insipidus
Blood Glucose Regulation
Insulin
Glucagon
Other Factors Influencing Blood Glucose Regulation
Pathophysiological Changes Associated with Diabetes Mellitus
Epidemiology
Risk Factors
Clinical Presentation
Clinical Investigations and Diagnosis
Management
Dietary Therapy
Non-insulin Therapy
Insulin Therapy
Monitoring Response to Therapy
Physical Activity
Education and Self-management Skills
Regular Medical Follow-up
Psychosocial Support
Complications, Screening and Prevention
Health Teaching
Conclusion
Glossary of Terms
Multiple Choice Questions
References
Chapter 6 Cushing’s Syndrome
Pathophysiological Changes Associated with Cushing’s Syndrome
Epidemiology
Risk Factors
Clinical Presentation
Clinical Investigations and Diagnosis
Management
Health Teaching
Conclusion
Glossary of Terms
Multiple Choice Questions
References
Chapter 7 Polycystic Ovarian Syndrome
Pathophysiological Changes Associated with Polycystic Ovarian Syndrome
Epidemiology
Risk Factors
Clinical Presentation
Clinical Investigations and Diagnosis
Diagnostic Criteria
Management
Health Teaching
Conclusion
Glossary of Terms
Multiple Choice Questions
References
Chapter 8 Pituitary Tumours
The Pituitary Gland: An Overview
Pituitary Tumours
Pathophysiological Changes Associated with Pituitary Tumours
Hypopituitarism and Hyperpituitarism
Epidemiology
Risk Factors
Clinical Presentation
Clinical Investigations and Diagnosis
Management
Observation and Monitoring
Medication Therapy
Surgery
Radiation Therapy
Combination Therapy
Pituitary Carcinoma
Follow-up Care
Health Teaching
Conclusion
Glossary of Terms
Multiple Choice Questions
References
Index
End User License Agreement
Chapter 1
Figure 1.1 The endocrine organs and their location in the body
Figure 1.2 The transportation of hormones in the blood
Figure 1.3 Target cells and non-target cells
Figure 1.4 The negative feedback system
Figure 1.5 The hypothalamus and surrounding structures
Figure 1.6 Position of the adrenal glands
Figure 1.7 Transverse section of an adrenal gland
Figure 1.8 The thyroid and parathyroid glands
Figure 1.9 Control of thyroid hormone production and negative feedback mechanism
Figure 1.10 The pancreas
Figure 1.11 Insulin and glucagon effects on blood glucose
Chapter 2
Figure 2.1 Endocrine disorders across the lifespan.
Figure 2.2 The patient encounter
Figure 2.3 Clinical features of acromegaly and the face of a man with acromegaly
Chapter 3
Figure 3.1 The negative feedback control of thyroid hormone production. TSH, thyroid...
Figure 3.2 Hyperthyroidism
Chapter 4
Figure 4.1 Hypothyroidism
Chapter 5
Figure 5.1 Insulin and glucagon effects on blood glucose levels
Figure 5.2 Insufficient insulin leading to the development of type 1 diabetes
Figure 5.3 Insulin resistance
Figure 5.4 Metabolic syndrome
Figure 5.5 HbA1c measurement
Figure 5.6 Signs and symptoms of type 1 diabetes
Figure 5.7 Insulin pump.
Figure 5.8 Insulin pod
Figure 5.9 Correct performance of a skinfold
Figure 5.10 Taking a capillary blood glucose
Figure 5.11 Blood‐glucose monitoring procedure
Figure 5.12 Injection sites
Figure 5.13 Correct and incorrect depth of injection needles
Figure 5.14 Correct administration of an insulin injection using an injection pen
Figure 5.15 Layers of skin, fat and muscle (not to scale): the tip of a 4mm needle ...
Chapter 6
Figure 6.1 Cushing’s syndrome
Chapter 7
Figure 7.1 The pathophysiology associated with polycystic ovarian syndrome (PCOS)
Figure 7.2 Hirsutism in a patient with polycystic ovarian syndrome (PCOS)
Figure 7.3 Patient-centred approach can help achieve the key goals of PCOS management
Chapter 8
Figure 8.1 The pituitary gland and surrounding structures
Figure 8.2 Hypopituitarism
Figure 8.3 Transsphenoidal surgery
Chapter 1
Table 1.1 The differences between the nervous system and endocrine system
Table 1.2 Hormones released by the anterior pituitary gland
Table 1.3 Effects associated with abnormal secretion of thyroid hormones
Table 1.4 Other endocrine glands
Chapter 2
Table 2.1 Assessing needs
Table 2.2 Some common clinical features observed in endocrine disease
Table 2.3 The patient’s chief complaint of fatigue
Table 2.4 Certain features associated with some endocrine conditions
Table 2.5 Changes in facial features associated with some endocrine disorders
Table 2.6 Some aspects of thyroid gland assessment
Chapter 3
Table 3.1 Some risk factors associated with hyperthyroidism
Table 3.2 Some signs and symptoms associated with hyperthyroidism
Table 3.3 Treatment modalities for hyperthyroidism
Chapter 4
Table 4.1 Some risk factors associated with hypothyroidism
Table 4.2 Symptoms of hypothyroidism
Table 4.3 Examples of dynamic hormone testing
Chapter 5
Table 5.1 Pathophysiological changes associated with type 2 diabetes
Table 5.2 Type 2 and type 1 diabetes clinical presentation comparison
Chapter 6
Table 6.1 Cortisol
Table 6.2 Some of the risk factors associated with Cushing’s syndrome
Table 6.3 Potential imaging studies
Table 6.4 Issues associated with health teaching and Cushing’s syndrome
Chapter 7
Table 7.1 Metabolism associated with polycystic ovarian syndrome (PCOS)
Table 7.2 Inflammatory markers
Table 7.3 Some risk factors associated with polycystic ovarian syndrome (PCOS)
Table 7.4 Diagnosing polycystic ovarian syndrome (PCOS)
Chapter 8
Table 8.1 Hypopituitarism and Hyperpituitarism
Table 8.2 Signs and symptoms commonly associated with pituitary tumours related to cell ...
Table 8.3 Components of the physical examination
Table 8.4 Microadenomas and macroadenomas
Table 8.5 Some key health teaching needs for those with pituitary tumours
Cover
Table of Contents
Title Page
Copyright
Preface
Acknowledgements
Begin Reading
Index
End User License Agreement
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Ian Peate, OBE FRCN EN(G) RGN DipN(Lond) RNT BEd(Hons) MA(Lond) LLM
Editor in Chief, British Journal of Nursing;
Consultant Editor, Journal of Paramedic Practice;
Consultant Editor, International Journal for Advancing Practice;
Visiting Professor, Northumbria University;
Visiting Professor, Buckinghamshire New University;
Professorial Fellow, University of Roehampton;
Visiting Senior Clinical Fellow, University of Hertfordshire
This edition first published 2025.
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Library of Congress Cataloging-in-Publication Data
Names: Peate, Ian, author.
Title: The endocrine system / Ian Peate, OBE FRCN EN(G) RGN DipN(Lond) RNT Bed BEd (Hons) MA(Lond) LLM Editor in Chief, British Journal of Nursing; Consultant Editor, Journal of Paramedic Practice; Consultant Editor, International Journal for Advancing Practice; Visiting Professor, Northumbria University; Visiting Professor, St Georges University of London and Kingston University London; Professorial Fellow, Roehampton University; Visiting Senior Clinical Fellow, University of Hertfordshire.
Description: Hoboken, NJ : Wiley-Blackwell, 2025. | Series: Peate’s body systems ; 6 | Includes bibliographical references and index.
Identifiers: LCCN 2024042311 (print) | LCCN 2024042312 (ebook) | ISBN 9781394252503 | ISBN 9781394252510 (epub)
Subjects: LCSH: Endocrine glands–Textbooks. | Endocrine glands–Diseases–Textbooks. | Endocrinology–Textbooks.
Classification: LCC QP187 .P393 2025 (print) | LCC QP187 (ebook) | DDC 612.4–dc23/eng/20250102
LC record available at https://lccn.loc.gov/2024042311
LC ebook record available at https://lccn.loc.gov/2024042312
Cover Images: © marinashevchenko/Adobe Stock, © phototechno/Getty Images, © 4luck/Adobe Stock, © Oleksandr Pokusai/Adobe Stock
Cover Design: Wiley
Welcome to Peate’s Body Systems; there are 12 books in the series. This is a comprehensive collection of textbooks designed to support and enrich the knowledge of health and care workers across various fields. This series is intended to be a valuable resource for those who are dedicated to understanding the intricacies of human biology, physiology and the various systems that sustain life.
Peate’s Body Systems series is rooted in the belief that a deep and thorough understanding of the human body is essential for providing the highest standard of care. Each book in this series is thoroughly crafted to offer clear, accurate and up-to-date information on different body systems. The aim is to bridge the gap between complex scientific concepts and practical, everyday applications in healthcare settings.
The purpose of this series is to provide health and care workers with:
Foundational knowledge, with explanations of the anatomical structures and physiological functions of the body systems
Insights into how these systems interact with each other and how they are impacted by various diseases and conditions, highlighting clinical relevance and encouraging practical application
Each book in Peate’s Body Systems focuses on a specific body system:
The Cardiovascular System
The Respiratory System
The Digestive System
The Renal System
The Nervous System
The Endocrine System
The Female Reproductive System
The Male Reproductive System
The Musculoskeletal System
The Skin
The Ear, Nose and Throat
The Eyes
Every chapter is designed to be comprehensive yet accessible, making complex information easier to digest and apply. Figures, tables, boxes, illustrations and flowcharts have been extensively used to support visual learning and reinforce key concepts.
This series is tailored for:
Healthcare students: those in nursing and allied health programmes
Practicing professionals: nurses, therapists and other care workers seeking to deepen their understanding and stay current with the latest developments in health and care
Educators and trainers: educators who require reliable and comprehensive teaching materials to advise and instruct the next generation of healthcare providers
The series is committed to providing quality educational resources that not only inform but also inspire and empower health and care workers. By equipping you with a robust understanding of the systems of life, you will be better prepared to make informed decisions, deliver compassionate care and ultimately improve patient outcomes.
Thank you for choosing Peate’s Body Systems as your trusted resource. I hope these textbooks serve as a valuable tool in your ongoing journey of learning and professional development.
Ian Peate
London
I would like to acknowledge the help and support of my partner Jussi Lahtinen. Acknowledgements also go to staff at the RCN Library in London. My thanks go to Tom Marriott, Christabel Daniel Raj, Bhavya Boopathi and all those at Wiley.
