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Ian Peate

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PEATE’S BODY SYSTEMS THE NERVOUS SYSTEM

A CONCISE, ILLUSTRATED, AND ACCESSIBLE GUIDE TO THE NERVOUS SYSTEM

Each of the twelve volumes in Peate’s Body Systems series is rooted in the belief that a deep and thorough understanding of the human body is essential for providing the highest standard of care. Offering clear, accessible and up-to-date information on different body systems, this series bridges the gap between complex scientific concepts and practical, everyday applications in health and care settings. This series makes for an invaluable resource for those committed to understanding the intricacies of human biology, physiology and the various systems that sustain life.

The Nervous System is the perfect companion for students and newly registered practitioners across nursing and allied health fields with an interest in neurological care, providing a comprehensive yet easy-to-digest guide for both academic and clinical application.

  • Equips healthcare students and practitioners with the necessary information to provide safe and competent care
  • Features colourful illustrations to aid comprehension, clarify complicated concepts, and render content more engaging and accessible
  • Empowers readers to adapt to a rapidly evolving healthcare landscape, preparing them for the future of healthcare delivery
  • Contains information necessary for effective patient care of those with stroke, dementia, Multiple Sclerosis (MS), and other diseases and conditions of the nervous system

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Seitenzahl: 311

Veröffentlichungsjahr: 2025

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Table of Contents

Cover

Table of Contents

Title Page

Copyright

Preface

Acknowledgements

Chapter 1 Anatomy and Physiology: The Nervous System

Organisation of the Nervous System

Sensory Division of the Peripheral Nervous System

Central Nervous System

Motor Division of the Peripheral Nervous System

Neurotransmitters

Neuroglia

Meninges

The Cerebrospinal Fluid

Brain

The Blood Supply to the Brain

Circle of Willis

The Peripheral Nervous System

The Autonomic Nervous System

Sympathetic Division

Parasympathetic Division

Conclusion

Glossary of Terms

Multiple Choice Questions

References

Chapter 2 Assessment of the Nervous System

Assessing Needs

Assessing the Level of Consciousness

Vital Signs

Assessment of Pupillary Reaction

Motor and Sensory Assessments

The Patient History

Physical Examination

Assessing Mental Status

Cranial Nerve Assessment

Evaluating the System: Diagnostic Tests

Conclusion

Glossary of Terms

Multiple Choice Questions

References

Chapter 3 Stroke

Pathophysiological Changes Associated with Stroke

Ischaemic Stroke

Haemorrhagic Stroke

Cellular and Molecular Events

Epidemiology

Risk Factors

Non-modifiable Risk Factors

Modifiable Risk Factors

Clinical Presentation

Ischaemic Stroke

Haemorrhagic Stroke

Transient Ischaemic Attacks

The FAST Acronym

Clinical Investigations and Diagnosis

Onset and Duration of Symptoms

Nature of Symptoms

Previous Strokes or Transient Ischaemic Attacks

Medical History

Risk Factors

Medication and Allergies

Social History

Psychosocial History

Pre-existing Conditions

Recent Procedures or Surgeries

Timing of Presentation to Healthcare Provider

Patient’s Perspective

Management

Post-acute and Long-term Management

Health Teaching

Conclusion

Glossary of Terms

Multiple Choice Questions

References

Chapter 4 Dementia

Pathophysiological Changes Associated with Dementia

Confusion

Mild Cognitive Impairment

Prognosis

Epidemiology

Risk Factors

Other Risk Factors

Clinical Presentation

Clinical Investigations and Diagnosis

Management

Caregiver Support

Symptom Management

Health Teaching

Conclusion

Glossary of Terms

Multiple Choice Questions

References

Chapter 5 Multiple Sclerosis

Pathophysiological Changes Associated with Acute Multiple Sclerosis

Prognosis

Epidemiology

Risk Factors

Clinical Presentation

Clinical Investigations and Diagnosis

Management

Supportive Care

Health Teaching

Conclusion

Glossary of Terms

Multiple Choice Questions

References

Chapter 6 Epilepsy

Equality and Law

Pathophysiological Changes Associated with Epilepsy

Epidemiology

Risk Factors

Clinical Presentation

Clinical Investigations and Diagnosis

Management

Seizure First Aid

Mental Health and Well-being

Equality and Diversity

Treatment Goals

Health Teaching

Conclusion

Glossary of Terms

Multiple Choice Questions

References

Chapter 7 Raised Intracranial Pressure

Idiopathic Intracranial Hypertension

Pathophysiological Changes Associated With Raised Intracranial Pressure

Consequences of Raised Intracranial Pressure

Epidemiology

Socioeconomic Factors

Risk Factors

Clinical Presentation

Clinical Investigations and Diagnosis

Management

Monitoring

Medical Management

Ventilation Management

Surgical Interventions

Cerebrospinal Fluid Drainage

Psychological and Emotional Needs

Multidisciplinary Approach

Prognosis and Follow-up

Health Teaching

Conclusion

Glossary of Terms

Multiple Choice Questions

References

Chapter 8 Traumatic Brain Injury

Head Injury

Pathophysiological Changes Associated with Traumatic Brain Injury

Mechanisms of Injury

Location of the Injury

Open Versus Closed Brain Injuries

Secondary Injuries

Epidemiology

Risk Factors

Clinical Presentation

Severity of Symptoms

Symptoms of Specific Types of Traumatic Brain Injury

Clinical Investigations and Diagnosis

Management

Health Teaching

Understanding the Injury and Its Effects

Medication Management

Cognitive and Physical Rehabilitation

Emotional and Psychological Support

Preventing Complications

Safety Measures

Conclusion

Glossary of Terms

Multiple Choice Questions

References

Index

End User License Agreement

List of Illustrations

Chapter 1

Figure 1.1 Organisation of the nervous system

Figure 1.2 Motor neurone

Figure 1.3 Neuroglia

Figure 1.4 The meninges

Figure 1.5 The ventricles

Figure 1.6 The brain

Figure 1.7 The cerebrum

Figure 1.8 The cerebellum

Figure 1.9 The limbic system

Figure 1.10 The circle of Willis

Figure 1.11 The blood–brain barrier

Figure 1.12 Functions of cranial nerves

Figure 1.13 The spinal cord

Figure 1.14 The spinal cord and spinal nerves

Figure 1.15 Sympathetic nervous system

Figure 1.16 Parasympathetic nervous system

Chapter 2

Figure 2.1 Central pain stimulus for assessment of consciousness (a) supraorbital ridge p...

Figure 2.2 Pupil observations.

Figure 2.3 Motor response

Figure 2.4 Recording of the Glasgow Coma Scale

Figure 2.5 Neurological assessment

Chapter 3

Figure 3.1 Blood flow through the brain

Figure 3.2 Atherosclerosis

Figure 3.3 Ischaemia of brain tissue following vessel blockage

Figure 3.4 Haemorrhagic stroke

Figure 3.5 Clipping of an aneurysm

Chapter 4

Figure 4.1 Vascular dementia symptoms

Chapter 5

Figure 5.1 Demyelination

List of Tables

Chapter 1

Table 1.1 The cranial nerves

Table 1.2 Effects of the parasympathetic and sympathetic divisions of the autonomic nerv...

Chapter 2

Table 2.1 Some common terms used to describe level of consciousness

Table 2.2 The Glasgow Coma Scale

Table 2.3 The AVPU scale

Table 2.4 An overview of neurological observations

Table 2.5 An overview of headache

Table 2.6 Components of the neurological system history

Table 2.7 Some common manifestations of neurological problems

Table 2.8 Equipment needed to undertake a physical examination of the neurological syste...

Table 2.9 Assessing the cranial nerves (in the conscious patient)

Chapter 3

Table 3.1 Area of brain damaged according to side of brain affected

Table 3.2 The pathogenesis associated with stroke

Table 3.3 Modifiable risk factors associated with stroke

Table 3.4 FAST (American Stroke Association, https://www.stroke.org/en/about-stro...

Table 3.5 Key elements of the physical examination associated with stroke

Table 3.6 Investigations commonly used in the evaluation of a patient suspected of havin...

Table 3.7 Common deficits associated with stroke

Table 3.8 An overview of health teaching associated with stroke

Chapter 4

Table 4.1 A summary of the pathophysiological processes associated with dementia

Table 4.2 Differences between delirium and dementia

Table 4.3 Some epidemiological issues associated with dementia

Table 4.4 Additional risk factors associated with dementia

Table 4.5 Clinical presentation associated with dementia

Table 4.6 Symptoms related to specific subtypes of dementia

Table 4.7 Key health teaching needs for people with dementia

Chapter 5

Table 5.1 Risk factors associated with multiple sclerosis

Table 5.2 Red flags for alternative diagnoses in the context of multiple sclerosis

Table 5.3 An overview of the physical examination associated with a multiple sclerosis d...

Table 5.4 A summary of management approaches

Table 5.5 Key health teaching needs for those with multiple sclerosis

Chapter 6

Table 6.1 A summary of the pathophysiological changes that may occur in epilepsy

Table 6.2 Risk factors associate with epilepsy

Table 6.3 Key components of history taking and epilepsy

Table 6.4 Clinical investigations associated with making a diagnosis of epilepsy

Table 6.5 A summary of the treatment and management of epilepsy (Smith and Chadwick)

Table 6.6 Myths that exist surrounding epilepsy

Chapter 7

Table 7.1 Idiopathic intracranial hypertension and raised intracranial pressure

Table 7.2 Risk factors associated with raised intracranial pressure

Table 7.3 Acute situations related to potential neurological emergencies

Table 7.4 Highlights of diagnosis, raised intracranial pressure

Table 7.5 Some surgical interventions

Chapter 8

Table 8.1 Brain injury classification

Table 8.2 Symptoms associated with specific types of traumatic brain injury (NICE 2023a,...

Table 8.3 Components of the physical examination

Table 8.4 An overview of care and management of people with traumatic brain injury

Guide

Cover

Table of Contents

Title Page

Copyright

Preface

Acknowledgements

Begin Reading

Index

End User License Agreement

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Peate’s Body Systems

The Nervous System

Ian Peate, OBE FRCN EN(G) RGN DipN(Lond) RNT BEd(Hons) MA(Lond) LLM

Editor in Chief, British Journal of Nursing;

Consultant Editor, Journal of Paramedic Practice;

Consultant Editor, International Journal for Advancing Practice;

Visiting Professor, Northumbria University;

Visiting Professor, Buckinghamshire New University;

Professorial Fellow, University of Roehampton;

Visiting Senior Clinical Fellow, University of Hertfordshire

This edition first published 2025.

©2025, John Wiley & Sons Ltd

All rights reserved, including rights for text and data mining and training of artificial intelligence technologies or similar technologies. No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, except as permitted by law. Advice on how to obtain permission to reuse material from this title is available at http://www.wiley.com/go/permissions.

The right of Ian Peate to be identified as the author of this work has been asserted in accordance with law.

Registered Office(s)

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While the publisher and authors have used their best efforts in preparing this work, they make no representations or warranties with respect to the accuracy or completeness of the contents of this work and specifically disclaim all warranties, including without limitation any implied warranties of merchantability or fitness for a particular purpose. No warranty may be created or extended by sales representatives, written sales materials or promotional statements for this work. This work is sold with the understanding that the publisher is not engaged in rendering professional services. The advice and strategies contained herein may not be suitable for your situation. You should consult with a specialist where appropriate. The fact that an organization, website, or product is referred to in this work as a citation and/or potential source of further information does not mean that the publisher and authors endorse the information or services the organization, website, or product may provide or recommendations it may make. Further, readers should be aware that websites listed in this work may have changed or disappeared between when this work was written and when it is read. Neither the publisher nor authors shall be liable for any loss of profit or any other commercial damages, including but not limited to special, incidental, consequential, or other damages.

Library of Congress Cataloging-in-Publication Data

Names: Peate, Ian, author.

Title: The nervous system / Ian Peate, OBE FRCN EN(G) RGN DipN(Lond) RNT Bed BEd (Hons) MA(Lond) LLM Editor in Chief, British Journal of Nursing; Consultant Editor, Journal of Paramedic Practice; Consultant Editor, International Journal for Advancing Practice; Visiting Professor, Northumbria University; Visiting Professor, St Georges University of London and Kingston University London; Professorial Fellow, Roehampton University; Visiting Senior Clinical Fellow, University of Hertfordshire.

Description: Hoboken, NJ : Wiley Blackwell, 2025. | Series: Peate’s Body systems ; 5 | Includes bibliographical references and index.

Identifiers: LCCN 2024041160 (print) | LCCN 2024041161 (ebook) | ISBN 9781394252473 | ISBN 9781394252480 (epub)

Subjects: LCSH: Nervous system–Textbooks. | Brain–Textbooks.

Classification: LCC QP361 .P43 2025 (print) | LCC QP361 (ebook) | DDC 612.8–dc23/eng/20241213

LC record available at https://lccn.loc.gov/2024041160

LC ebook record available at https://lccn.loc.gov/2024041161

Cover Images: © marinashevchenko/Adobe Stock, © phototechno/Getty Images, © 4luck/Adobe Stock, © Oleksandr Pokusai/Adobe Stock

Cover Design: Wiley

Preface

Welcome to Peate’s Body Systems; there are 12 books in the series. This is a comprehensive collection of textbooks designed to support and enrich the knowledge of health and care workers across various fields. This series is intended to be a valuable resource for those who are dedicated to understanding the intricacies of human biology, physiology and the various systems that sustain life.

Peate’s Body Systems series is rooted in the belief that a deep and thorough understanding of the human body is essential for providing the highest standard of care. Each book in this series is thoroughly crafted to offer clear, accurate and up-to-date information on different body systems. The aim is to bridge the gap between complex scientific concepts and practical, everyday applications in healthcare settings.

Purpose and Scope

The purpose of this series is to provide health and care workers with:

Foundational knowledge, with explanations of the anatomical structures and physiological functions of the body systems

Insights into how these systems interact with each other and how they are impacted by various diseases and conditions, highlighting clinical relevance and encouraging practical application

Structure of the Series

Each book in Peate’s Body Systems focuses on a specific body system:

The Cardiovascular System

The Respiratory System

The Digestive System

The Renal System

The Nervous System

The Endocrine System

The Female Reproductive System

The Male Reproductive System

The Musculoskeletal System

The Skin

The Ear, Nose and Throat

The Eyes

Every chapter is designed to be comprehensive yet accessible, making complex information easier to digest and apply. Figures, tables, boxes, illustrations and flowcharts have been extensively used to support visual learning and reinforce key concepts.

This series is tailored for:

Healthcare students: those in nursing and allied health programmes

Practicing professionals: nurses, therapists and other care workers seeking to deepen their understanding and stay current with the latest developments in health and care

Educators and trainers: educators who require reliable and comprehensive teaching materials to advise and instruct the next generation of healthcare providers

Commitment to Excellence.

The series is committed to providing quality educational resources that not only inform but also inspire and empower health and care workers. By equipping you with a robust understanding of the systems of life, you will be better prepared to make informed decisions, deliver compassionate care and ultimately improve patient outcomes.

Thank you for choosing Peate’s Body Systems as your trusted resource. I hope these textbooks serve as a valuable tool in your ongoing journey of learning and professional development.

Ian Peate

London

Acknowledgements

I would like to acknowledge the help and support of my partner Jussi Lahtinen. Acknowledgements also go to staff at the RCN Library in London. My thanks go to Tom Marriott, Christabel Daniel Raj, Bhavya Boopathi and all those at Wiley.