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Some people have been suffering for more than a year with no answers, no treatment options not even a forecast of what the future may hold. Researchers and data collection from scientists on post-COVID-19 illness had identified several neurological symptoms involving numbers of neurological disorder as listed below:
In this book will address the diagnosis of those symptoms as related to Post COVD infection or as pre-existing chronical illnesses
1. Doing tasks in the wrong order
2. Finding difficulty to do multi tasks at the same time
3. Forgetting to do things often
4. Working on automatic; not thinking
5. Headache and getting tired after performing small task
6. Memory, concentration, or sleep problems
7. Depression or anxiety
8. Feeling tired or yawning all the time
9. Being more irritable than usual
10. Being frustrated by tasks
11. Having difficulty concentrating
12. Loss of smell
13. Vertigo symptoms
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Frank Hamo
Post COVID-19 Long Hauler
Neurological Disorder
All rights reserved
Copyright © 2023 by Frank Hamo
No part of this publication may be reproduced, distributed, or transmitted in any form or by any means, including photocopying, recording, or other electronic or mechanical methods, without the prior written permission of the publisher, except in the case of brief quotations embodied in critical reviews and certain other noncommercial uses permitted by copyright law.
Published by BooxAI
ISBN: 978-965-578-134-2
1. Book Executive Summary
1.0 Book Executive Summary
Figure one: Brain Executive Functions
2. Brain Anatomy Educational Information
2.0 Brain Major Parts Anatomy
Figure two: Brain anatomy showing four lobes, cerebellum, and spinal cord
BRAIN ANATOMY EDUCATIONAL INFORMATION
Figure three: Brain High level Functions Illustration
Figure four: Brain High Level Four Lobes Functional Descriptions
2.1 How Brain Communicates
2.1.1 How Brain Neuron Sends and Receives Messages
Figure five: How Brain Communicates
Figure six: Brain parts responsible to performing tasks
2.2 Human Brain Parts Functional Descriptions Overview
Table one: Four Lobes Functions
Figure seven: Brain Lobes Functions Detailed Illustration
Figure eight: Brain Limbic System
2.3 Brain Memory
2.4 Ventricles and cerebrospinal fluid
2.5 Cranial nerves
Table two: Cranial Nerves
2.6 Brain Blood supply
2.7 Brain Cells
Figure ten: Glial Cells Anatomy
3. Detailed Description of Brain communications
3.0 Neurons are information messengers
3.1 Soma (cell body)
3.2 Memory may also involve the creation of new synapses
Figure eleven: Brain Neurological Cells
3.3 Deep Dive into Brain Internal Communication
Figure twelve: Synapse Anatomy
Figure thirteen: Chemical Synapse
4. How Coronavirus invades Brain Cells
Figure fourteen: COVID-19 Proteins Structures
4.0 Virus genetic structure encodes four or five structural proteins:
4.1 COVID-19 Brain Invasion Through Olfactory Explained
Figure fifteen: Astrocytes Cell Anatomy Illustration
Figure sixteen: Olfactory Nerve Anatomy
Figure seventeen: Olfactory Cells
Figure eighteen: Olfactory Physical Location Illustration
Figure nineteen: Olfactory Location Near Thalamus Illustration
4.2 COVID-19 Brain Invasion Through Lungs Capillary and Blood Flow Explained
Figure twenty: Virus Escapes from Alveoli
4.3 Brain Blood Brain Barrier
Figure twenty-one: Brain Blood Barrier
Figure twenty-two: Brain Blood Barrier under Electron Microscope
4.4 COVID virus was detected in brain tissues
Figure twenty-three: Inter Neurons
Figure twenty-four: Brain Injury Complication as a Result of COVID Brain Invasion
5. COVID-19 and Neurological Disorder problems
5.0 Brain Virus Entry Point
5.1 Neurological Disorders Symptoms and Causes
Table three: Post-COVID-19 Neurological Disorder Some Symptoms Still Under Investigation if COVID Related, this Book will address each Symptom.
Table four: Complete List of Neurological Disorders
5.2 Some examples of things a person might do because of brain fog include
5.3 Most Common Brain Fog Symptoms
Case Study A
5.4 Least Common Brain Symptoms
Case Study B
Figure twenty-five: Long Term Effects of COVID-19
5.5 Brain Lobes Function as Related to Brain Fog Symptoms
Table six: Brain Parts Functional Description
Figure twenty-six: Brain Lobes Functional Descriptions
Figure twenty-seven: Amygdala in the brain, and close-up view of amygdala neurons, 3D illustration.
Figure twenty-nine: Frontal Lobe Visualized Location
Figure thirty: Brain Right and Left Functional Description
6. Post COVID-19 Brain Fog Diagnosis
6.0 This section will address the most common brain fog symptoms following past COVID infection
Table seven: Brain Fog Most Common Symptoms.
6.1 Brain Fog: What causes it?
7. Symptom One
Forgetting About Tasks Started But Not Completed
7.1 Brain short-term memory damages evaluation
7.2 Concentration Prefrontal Lobe Damage
7.3 Astrocytes
7.4 Microglia
7.5 Glia damage control
Figure thirty-one: Neurological Cells Anatomy Illustration
7.6 Imaging Diagnosis for Symptom One
Figure thirty-two: Glia Cells Damages under Electron Microscope
Figure thirty-three: Brain Cells Astrocytes and Neuron Interrelationship Anatomy Illustration
7.7.1 MRI Advance Imaging Diagnose for Brain Fog Symptom One
Figure thirty-four: Ischemic stroke followed severe COVID infection.
Figure thirty-five: Multi MRI Scan for Frontal and Temp Lobes Infarct
Figure thirty-six: Multi MRI Scan for Frontal and Temp Lobes Infarct (Sample Image)
8. Symptom Two
Taking Much Longer Than Usual To Complete Simple Tasks
8.0 This symptom can be related to different factors rather than post-COVID infections as:
8.1 Physician Performs Imaging Diagnosis for Symptom two as Related to Post-COVID Infection
Figure thirty-seven: Evidence of PFC Degradation Enhanced MRI Sample Imaging
9. Symptom Three
Feeling Frequently Distracted
9.1 Experience occasional brain fog and anxiety
Figure thirty-eight: Which Parts of the Brain Responsible for Concentration
9.2 Physician Performs Enhanced MRI Imaging
Figure thirty-nine: MRI Scan for Prefrontal Cortex Evidence of Inflammation
10. Symptom Four
Feeling Tired When Working
Identifying brain damaged parts can relate to symptom four.
10.1 Coronavirus potentially triggering chronic fatigue syndrome
Figure forty: Hypothalamus Stress Response Anatomy Illustration
10.2 Physician Performs Enhanced MRI Imaging for Hypothalamus as a Result of Stress Syndrome
Figure forty-one: Diagnosis for Hypothalamus MRI Scan evidence of any previous damaged as a result of post-COVID infection
11. Symptom Five
Needing More Time To Complete Small Tasks
Identifying brain damaged parts can relate to symptom five.
11.1 Attention-deficit hyperactivity disorder affects behavior
11.2 Brain Areas to be Examined
Figure forty-two: Anterior cingulate Anatomy Illustration
11.3 Frontal, basal ganglia Anatomy Illustration
Figure forty-three: Front Ganglia AnatomySymptom Five Diagnosis and Enhance MRI Imaging
11.4 Physician Performs Enhanced MRI Scan for Ganglia
Figure forty-four: Enhanced MRI Sample scan of Basal Ganglia Evidence of Post-COVID Infection
12. Symptom Six
Finding Difficulty Sleeping
Identifying brain damaged parts can relate to symptom six.
12.1 Difficulties Sleeping due to COVID Infection.
12.2 Brain Parts Responsible for Sleeping
12.3 Brain Parts Involved in Sleeping Anatomy Illustration
Figure forty-five: Pineal Glands Anatomy
12.4 Sleep Deprivation Caused by Post-COVID Infection
Figure forty-six: Physician performs enhanced MRI Sample scanning for evidence of any damage to the brain hypothalamus gland as a result of post-COVID infection
Figure forty-seven: Hypothalamus Damage Assessment Sample Scan
13. Being More Irritable Than Usual
Identifying brain damaged parts can relate to symptom seven.
13.1 Irritability is a common emotion.
13.2 Damaged Amygdala as a result of post-COVID Infection, MRI Scan
Figure forty-eight: Amygdala Location
Figure forty-nine: Limbic System Glands Details Anatomy Illustration
Figure fifty: Enhanced MRI Amygdala Sample Scan
Figure fifty-one: cerebral cortex (Sample Scan)
Figure fifty-two: Cerebral Cortex Infarct Enhanced MRI Sample Scan
Cerebral Cortex Blood Clots as Result from COVID Severe Infection
14. Symptom Eight
Being Frustrated By Tasks
14.1 Neural representations of tasks
14.2 Prefrontal Cortex Thalamus
Figure fifty-three: Previous COVID Infection Simple Image
Figure fifty-four: Thalamus Sample MRI Scan
15. Symptom Nine
Anxiety is Often Driven by Many Factors Other than Post COVID Infection
15.1 Anxiety and COVID-19
15.2 Factors can trigger anxiety as:
15.3 Common Triggers Related to post-COVID Infection
Figure fifty-five: No evidence of any brain damage is related to anxiety. Illustration.
16. Symptom Ten
Forgetting To Do Things Often
16.1 Forgetfulness
16.2 Frontal lobe of the cerebral cortex
Figure fifty-six: Normal Brain MRI
16.2.1 Doing tasks in the wrong order
16.3 Dementia damage showing in MRI Scan
Figure fifty-seven: Advanced Dementia Sample Scan
17. Symptom Eleven
Headache And Being Uncommunicative
Identifying Brain Parts Damage Can Relates to Symptom Eleven
17.1 Brain Area of Investigation for being uncommunicative
18. Symptom Twelve
Working On Automatic, Not Thinking
18.1 Brain Making Judgment
18.2 Having Difficulty Concentrating
19. Symptom Thirteen
Vertigo Balance Problem
19.1 Vertigo Caused by Post-COVID Infection
19.2 Vestibular Neuritis
Figure fifty-eight: Inner Ear Anatomy Illustration
19.3 Vertigo vector illustration
Figure fifty-nine: Vertigo Management
Table eight: Summary of Brain Symptoms and Area of Diagnosis
19.4 What are Post-COVID Dizziness Symptoms?
19.5 Understanding General Causes Of Dizziness And Imbalance
19.5.1 How does COVID-19 cause dizziness?
19.6 When Does Dizziness From Long COVID Start?
19.6 Dizziness And Vertigo After COVID-19 Vaccination
20. Managing Vertigo
20.2 Treatment Of Vestibular Neuronitis Physician Recommendation Is Advised
21. How Can Covid Affect Memory And Thinking
22. Symptoms: Questions And Answers
22.1 Why Does COVID Affect Memory and Thinking?
22.1.1 Fatigue
22.1.1 Fear and Anxiety
22.1.3 Low mood
22.2 Brain inflammation
23. Managing Neurological Problems
23.1 Managing Attention and Concentration Problems
23.1.1 Managing Memory Problems
23.1.2 Managing Executive Problems
24. When You Need To See A Doctor
24.1 What signs should someone look out for? And when should they go to a doctor about brain fog?
25. Brain Anatomy Reference Diagrams
Diagram A1: Human Brain Diagram
Diagram A2: Median Section of the BrainDiagram
Diagram A3: Brain Nucleus
Diagram A4: Brain High Mental Function
A5: Brain Concentration and Planning
Diagram A6: Brain Sulcus and Gyrus Diagram
What is the brain sulcus and gyrus?
Diagram A7: Brain Nerve System
Diagram A8: Brain MRI Lobes Infarct
Diagram A9: Brain Detailed Synaptic
Diagram A10: Brain Neuron Communication
Diagram A11: Brain Left and Right Function
Diagram A12: Limbic System Physical Location
Diagram A13: Brain Blood Supply Showing Arteries Blood Clots
Diagram A14: Brain Peripheral Nerve System
Diagram A15: Brain Neuron Anatomy
Diagram A16: Brain Synaptic Transmission
26. Other Post-COVID-19 Symptoms Related To Different Organs
26.1 Other Post-COVID-19 symptoms are broken down into the following categories:
26.2 List of identified post-COVID-19 symptoms from trusted scientific sources for information only
About the Author
Many people who have been sick with COVID-19, some who had mild or no symptoms, reported dealing with additional symptoms long after their acute illness ended. The long-haul COVID-19 symptoms can range from fatigue or headaches to mental health issues or chronic pain, involving multiple organ tissues damage due to the immune system cytokine storm response to the virus infection. It can ravage healthy cells during the process of fighting the infection.
Some people have been suffering for more than a year with no answers, no treatment options—not even a forecast of what the future may hold.
Researchers and data collection from scientists on post-COVID-19 illness had identified a few symptoms involving multiorgan symptoms as:
Brain neurological and limbic system COVID-related symptomsCardiovascular system COVID-related symptomsRespiratory system COVID-related symptomsLiver system COVID-related symptomsRenal system COVID-related symptomsGastrointestinal system COVID-related symptomsThis book will concentrate on post-COVID-19 neurological disorders as a focus point by providing the patients with enough information on reported symptoms and detailed information about which parts of the brain are responsible for these symptoms.
Note these symptoms can be triggered by different factors other than post- COVID infection.
This book will address screening and MRI diagnosis for the following symptoms as listed below. The provided samples of illustrated images are for informational and educational purposes only. Doctors can advise more images of diagnosis if required. Treatment options are beyond the scope of this book.
A- List of neurological disorder possibility results of post-COVID-19 infections or previous chronic conditions as listed below:
Doing tasks in the wrong orderFinding difficulty to do multi tasks at the same timeForgetting to do things oftenWorking on automatic, not thinkingHeadache and getting tired after performing small tasksMemory, concentration, or sleep problemsDepression or anxietyFeeling tired or yawning all the timeBeing more irritable than usualBeing frustrated by tasksHaving difficulty concentratingLoss of smellVertigoB- Introduction to brain anatomy
C- Brain modular lobe’s function
D- Defining brain parts related to post-COVID-19 neurological dis- order symptoms
E- Imaging diagnosis for brain parts malfunctions using MRI technology
F- Brain modulars and neurons communication
Enhanced MRI Screening is advised to isolate the symptoms, physician discretion is also advised.
Note: The symptoms that listed above can be caused by previous COVID infection as long hauler, or it can be caused by previous chronic illnesses. The purpose of this book is informational only for physicians and patients, and we do not provide solid evidence about this information. It is based on data collection from multiple clinical sources due to the fact most of these symptoms are still under clinical research and investigation.
Treatment option is beyond the scope of this book, and its physician and specialist decisions come after performing a detailed and in-depth screening evaluation.
This section will provide the reader with enough information to understand the functions of the brain’s main parts, including all four lobes. By comparing the parts’ function and the manifestation of the post-COVID symptoms, it will make it easier for the reader to understand which brain parts are affected by the virus when discussing the symptoms with their physicians.
The frontal lobes are important for voluntary movement, expressive language, and for managing higher level executive functions.
The temporal lobes are also believed to play an important role in processing emotions, language, and certain aspects of visual perception, understanding language learning, and remembering verbal information.
The occipital lobes sit at the back of the head and are responsible for visual perception, including color, form, and motion. Damage to the occipital lobe will result in difficulty with identifying colors.
The parietal lobes are responsible for processing somatosensory information from the body; this includes touch, pain, and temperature.