The Doctor's Guide to Gastrointestinal Health - Paul Miskovitz - E-Book

The Doctor's Guide to Gastrointestinal Health E-Book

Paul Miskovitz

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"This is the reference guide you dream about--answers to all your important questions written in a language you can understand. For everyone who wants better health and peace of mind." --Diane Sawyer, Co-anchor of ABC News' Good Morning America and PrimeTime Thursday "An important, practical, easy-to-read, and easy-to-understand source of information for anyone with a chronic gastrointestinal problem." --Isadore Rosenfeld, M.D., Rossi Distinguished Professor of Clinical Medicine at Weill Medical College of Cornell University and bestselling author Digestive ailments, whether mild or life-threatening, are a major concern for millions of people--and they can be difficult to diagnose and treat. Now, in this essential reference book, Dr. Paul Miskovitz, a physician at one of the world's top medical institutions, helps you understand the causes, symptoms, diagnoses, and medical treatments for a wide range of gastrointestinal disorders--everything from heartburn to IBS to hepatitis C. This comprehensive, user-friendly guide begins with an overview of how your gastrointestinal system works and how it is affected by lifestyle, age, and emotions. Dr. Miskovitz then explains the disorders that can affect your esophagus, stomach, intestine, gallbladder, liver, pancreas, colon, and abdominal cavity--revealing how to identify and treat problems and, in most cases, prevent them. You'll also learn how to: * Maintain a healthy gastrointestinal system through diet, exercise, checkups, and screenings * Find the right gastroenterologist for you * Identify symptoms and get an accurate diagnosis * Prevent gastrointestinal problems when you travel Complete with a list of organizations that provide information and support, The Doctor's Guide to Gastrointestinal Health is the ultimate resource for you and your family.

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Table of Contents
Praise
Also by the same authors
Title Page
Dedication
Copyright Page
Introduction
PART I - Understanding How Your Gut Works and How to Identify Problems
Chapter 1 - What We Know about the Gut: Yesterday, Today, and Tomorrow
How the Digestive System Works
Your Second Brain: The Mind-Gut Connection
Food Allergy and Food Intolerance
Lifestyle, Aging, and the Gastrointestinal System
Systemic Disease Can Cause Digestive Problems
Common Gastrointestinal Symptoms and Problems
Chapter 2 - How to Find a Gastroenterologist and the Proper Diagnosis
About Diagnostic Testing
Noninvasive Tests
Radiological Tests
Nuclear Scans
Chapter 3 - What You Need to Know about Endoscopic Procedures for Diagnosis and Treatment
Questions to Ask before You Get an Endoscopic Procedure
Manometry (Motility) Tests
Upper Endoscopy: Esophagogastroduodenoscopy
Esophageal pH Probe
Endoscopic Retrograde Cholangiopancreatography
Flexible Sigmoidoscopy
Colonoscopy
Small-Bowel Enteroscopy
Capsule Endoscopy or Capsule Camera
Endoscopic Ultrasonography
Diagnostic Endoscopy and Health Insurance: Why You Need to Be Well Informed
PART II - Medical Treatment for Disorders and Diseases of the Gastrointestinal System
Chapter 4 - The Esophagus
Gastroesophageal Reflux Disease
Benign Esophageal Tumors and Cancer
Other Disorders of the Esophagus
Chapter 5 - The Stomach
Dyspepsia, Gastritis, and Ulcers
Benign Gastric Tumors and Stomach Cancer
Other Disorders of the Stomach
Chapter 6 - The Small Intestine
Celiac Disease
Other Disorders of the Small Intestine
Chapter 7 - The Gallbladder
Gallstones
Other Conditions of the Gallbladder
Chapter 8 - The Pancreas
Pancreatitis and Pancreatic Cancer
Chapter 9 - The Liver
Hepatitis
Cholestatic and Metabolic Liver Diseases
Cirrhosis of the Liver and Liver Failure
Liver Biopsy, Tumors, Cancer, and Transplantation
Other Conditions of the Liver
Chapter 10 - The Colon and Rectum
Inflammatory Bowel Disease
Irritable Bowel Syndrome
Diverticulosis and Diverticulitis
Colon Polyps and Polyposis Syndromes
Colon Cancer
Anorectal and Perianal Disorders
Chapter 11 - The Abdominal Cavity
Abdominal Wall and Groin Hernias
Appendicitis
PART III - Maintaining Gastrointestinal Health
Chapter 12 - A Commonsense Guide to Diet and Exercise
Diet and Nutrition
Drink Plenty of Water
Exercise
Stay in Shape
Don’t Smoke
Alcohol in Moderation
Screening for Prevention
Preventing Gastrointestinal Problems When You Travel
Appendix: Resources
Index
About the Authors
Praise forThe Doctor’s Guide to Gastrointestinal Health
“This is the reference guide you dream about—answers to all your important questions, written in a language you can understand. For everyone who wants better health and peace of mind.”
—Diane Sawyer, co-anchor of ABCNews’ Good Morning America and Primetime Thursday
“An important, practical, easy-to-read and understand source of information for anyone with a chronic gastrointestinal problem.”
—Isadore Rosenfeld, M.D., attending physician at New York-Presbyterian Hospital and Memorial Sloan Kettering Cancer Center, Rossi Distinguished Professor of Clinical Medicine at Weill Cornell Medical Center, and bestselling author
“This book will provide for patients and their relatives authoritative, up-to-date information about most diseases of the gastrointestinal tract. The disorders are clearly explained and available treatments are outlined in clear language. Of special importance is the description of various diagnostic procedures used in gastroenterology, together with important information about what patients can expect before, during and after these treatments. This should go a long way toward relieving the anxiety that accompanies diagnostic procedures.”
—Jeremiah A. Barondess, M.D., president of The New York Academy of Medicine
“As a long time patient of Dr. Miskovitz, I highly recommend The Doctor’s Guide to Gastrointestinal Health for anyone wanting to know the vital importance of preventative procedures—before it’s too late. My wife and I have gone to Dr. Miskovitz for all our procedures and we’re still here—thanks in part to an early diagnosis.”
—Warner Wolf, TV and radio sportscaster and author of Let’s Go to the Videotape: All the Plays and Replays from My Life in Sports
Also by the same authors
What to Do If You Get Colon Cancer: A Specialist Helps You Take Charge and Make Informed Choices
Also by Marian Betancourt
What to Do If You Get Breast Cancer
Chronic Illness and the Family: A Guide for Living Every Day
The Prostate Cancer Sourcebook
What to Do When Love Turns Violent
Playing Like a Girl: Transforming Our Lives through Team Sports
The Coming Cancer Breakthrough
What’s in the Air:The Complete Guide to Seasonal and Year-Round Airborne Allergies
Say Goodbye to Back Pain
Also by Paul Miskovitz
The Evaluation and Treatment of the Patient with Diarrhea
For our families
Copyright © 2005 by Paul Miskovitz, M.D., and Marian Betancourt. All rights reserved
Published by John Wiley & Sons, Inc., Hoboken, New Jersey
Published simultaneously in Canada
Design and composition by Navta Associates, Inc.
No part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, scanning, or otherwise, except as permitted under Section 107 or 108 of the 1976 United States Copyright Act, without either the prior written permission of the Publisher, or authorization through payment of the appropriate per-copy fee to the Copyright Clearance Center, 222 Rosewood Drive, Danvers, MA 01923, (978) 750-8400, fax (978) 646-8600, or on the web at www.copyright.com. Requests to the Publisher for permission should be addressed to the Permissions Department, John Wiley & Sons, Inc., 111 River Street, Hoboken, NJ 07030, (201) 748-6011, fax (201) 748-6008.
Limit of Liability/Disclaimer of Warranty: While the publisher and the author have used their best efforts in preparing this book, they make no representations or warranties with respect to the accuracy or completeness of the contents of this book and specifically disclaim any implied warranties of merchantability or fitness for a particular purpose. No warranty may be created or extended by sales representatives or written sales materials. The advice and strategies contained herein may not be suitable for your situation. You should consult with a professional where appropriate. Neither the publisher nor the author shall be liable for any loss of profit or any other commercial damages, including but not limited to special, incidental, consequential, or other damages.
The information contained in this book is not intended to serve as a replacement for professional medical advice. Any use of the information in this book is at the reader’s discretion. The author and publisher specifically disclaim any and all liability arising directly or indirectly from the use or application of any information contained in this book. A health-care professional should be consulted regarding your specific situation.
For general information about our other products and services, please contact our Customer Care Department within the United States at (800) 762-2974, outside the United States at (317) 572-3993 or fax (317) 572-4002.
Wiley also publishes its books in a variety of electronic formats. Some content that appears in print may not be available in electronic books. For more information about Wiley products, visit our web site at www.wiley.com.
Library of Congress Cataloging-in-Publication Data:
Miskovitz, Paul F., date
The doctor’s guide to gastrointestinal health : preventing and treating acid reflux, ulcers, irritable bowel syndrome, diverticulitis, celiac disease, colon cancer, pancreatitis, cirrhosis, hernias, and more / Paul Miskovitz, Marian Betancourt. p. cm.
Includes bibliographical references and index.
ISBN 0-471-46237-3 (pbk.)
1. Gastrointestinal system—Diseases—Popular works. I. Betancourt, Marian. II. Title.
RC806.M57 2005
616.3’3—dc22
2004027081
Introduction
IN TODAY’S MANAGED HEALTH-CARE system, doctors have less time to educate their patients. At the same time, these patients have access to reams of health information on the Internet, but much of it can be more harmful than no information at all. With this book we hope to fill an urgent need for an easy-to-use but comprehensive book that helps you understand how the gastrointestinal system works and how to take care of it.
Digestive ailments—whether mild or life-threatening—can be difficult to diagnose and treat. Thus the field is surrounded by a lot of quasi-medical information and treatment, such as high colonic enemas, bio-ecological diets, and other fad diets that can cause real harm to your health. People sometimes resort to chiropractors, hypnotists, nutritionists, and self-medication instead of continuing their search for the correct medical diagnosis.
The Doctor’s Guide to Gastrointestinal Health is meant to inform you about diagnostic and treatment options available, so you know what questions to ask your doctor before any treatment begins.
In Part I, there’s an overview of how the gastrointestinal system works and how it is affected by lifestyle, age, and the mind. A section on common symptoms will help you know when you need medical attention. The role of the gastroenterologist and diagnostic testing is well covered, along with an entire chapter on endoscopic procedures that have transformed gastroenterology. There’s also important information about medical insurance coverage of these procedures.
Part II details causes, symptoms, diagnoses, and medical treatments for all of the disorders and diseases of the gastrointestinal system. It covers everything from top to bottom, in that order: esophagus, stomach, small intestine, gallbladder, pancreas, liver, colon and rectum, and the abdominal cavity.
And finally, Part III is a commonsense guide to maintaining a healthy gastrointestinal system, with guidelines for diet and exercise, checkups and screenings, as well as some precautions to take when you travel to other parts of the world.
In making The Doctor’s Guide to Gastrointestinal Health as comprehensive as possible, we hope it serves as a useful resource for you and your family. No matter what your concern or condition may be, this book will help you identify and treat the problem, and in many cases, help you prevent it.
PART I
Understanding How Your Gut Works and How to Identify Problems
Chapter 1
What We Know about the Gut: Yesterday, Today, and Tomorrow
OUR EARLY ANCESTORS probably never had the digestive problems we have today, even though they ate anything and everything they could find. While animals are generally pretty picky about what they eat, early humans had a diverse diet of nuts, berries, plants, fish, animals, bugs—you name it. And they ate the nutrient-rich stems, pits, roots, and husks of this matter as well.
When we evolved from hunter-gathering to agriculture, we added grains to our diet. With industrialization, mills refined our grains, removing the husks, bran, and cereal germ—and most of the nutrients along with it. Civilization led us toward food in boxes and packages from the shelves of supermarkets. Few people knew or cared about what was in that box or the consequences of eating its contents.
Our awareness has improved somewhat. Most of us now realize how poor nutrition and lack of exercise have lead to the obesity epidemic and a plethora of chronic digestive diseases. The shift in diet, along with smoking, drinking, and stress in the past hundred years, are directly related to the problems we face today. The good news is that we have the tools to diagnose digestive diseases early and have the means to cure many that were not curable in the past, such as peptic ulcers, celiac disease, and lactose intolerance.
Gastroenterology has developed into an amazingly precise discipline with the impact of technology and the evolution of concepts of specific diseases. We now understand gut secretions and gut hormones. We know how dietary elements are transported. As early as 1881, Polish surgeon Jan Mikulicz-Radecki used the first prototype “scope” to look into the esophagus. The development of fiberoptic endoscopy by Dr. Basil Isaac Hirschowitz gave us the tools to look inside the digestive tract and take away tissue samples or remove polyps. We learned that bacteria, not stress, in many cases caused stomach ulcers. In the 1980s an Australian physician, Barry Marshall, was so convinced ulcers were caused by H. pylori bacterium that he swallowed bacteria to prove his point to skeptical colleagues. While still a resident physician seventy-five years ago, Robert Elman discovered a way to diagnose that someone had pancreatitis. Some of the early heroes, with no sophisticated tools but their own curiosity and imagination, gave us other breakthroughs.

How the Digestive System Works

The digestive system sends us messages all the time. Our stomachs growl when we are hungry. We feel a burning sensation in our esophagus or stomach when we eat something irritating. We feel a knot in our stomach when we are upset. We might have a gut reaction to some encounters in our lives. We get a very particular urge when we have to go to the bathroom. All of these signals come from a complex system of dynamics that involves our entire physiology—blood, nerves, hormones, muscles—and its interaction with the brain.
A series of involuntary, wavelike muscle contractions propels your food in one direction along the alimentary tract—from the mouth to the anus. This action is called peristalsis. When your stomach gurgles, it is the sound of these peristaltic contractions propelling food along, an action you cannot feel. In the stomach, peristalsis produces a churning action that aids digestion. Circular muscles called sphincters are at the entrance to the esophagus and at the exits from the esophagus, the stomach, the lower small intestine, and the rectum, or anal opening. These muscles close tightly to prevent the process from going in reverse and causing one to vomit.
On its trip through the alimentary tract, food is broken down. Starches become simple sugars. Fats change to fatty acids and glycerin. Proteins become amino acids. The salivary glands in the mouth produce lubrication and enzymes and begin this conversion. The stomach stores and digests about one quart of food. Stomach muscles churn and mix with gastric juice, which includes hydrochloric acid and pepsin.
Within two to five hours, the digested food passes from the stomach to the duodenum, the first section of the small intestine. The small intestine is a twenty-plus-foot-long narrow, muscular tube—like a coiled soft rubber hose—that is made up of layers called the mucosa, the submucosa, and the serosa. The main function of the small intestine is the further digestion and absorption of nutrients. Also, enzymes from the pancreas, alkaline juices, and bile emulsifiers made by the liver and stored in the gallbladder enter the system at the duodenum level. Bile acids help dissolve (solubilize) dietary fats the way detergent dissolves grease in dishwater.
Most absorption, as well as digestion, occurs in the small intestine. Nutrients are absorbed into lymph fluids or blood vessels in the intestine wall (across the mucosa). Whatever cannot be digested in the small intestine, such as plant fiber, empties into the cecum at the lower right side of the abdomen. The cecum is the beginning of the large intestine, or colon. The colon, only about five feet long, is shorter than the small intestine but it is much wider (the girth is responsible for the label large intestine). The colon, positioned like a question mark, partially encircles the small intestine.
The main function of the large intestine is to absorb salt and water from all the remaining digested food that has been passed from the small intestine. In a healthy adult, more than a gallon of water, with more than an ounce of salt, is absorbed from the colon every four hours. Bacteria in the colon then convert fecal matter into its final form.
Digested matter travels upward from the cecum into the ascending colon, across the abdomen in the transverse colon, down the left side of the abdomen in the descending and s-shaped sigmoid colon, and into the rectum, where the solid waste is stored until it is eliminated. In doing this job, the colon produces a variety of substances, including carbon dioxide, hydrogen, methane, and the billions of bacteria that live in the colon.
All of this coiled tubing is supported by the mesentery, a membrane-like fold of tissue attached to the back of the abdominal cavity. The mesentery contains blood vessels, nerves, and the lymph system that interacts with the intestines.
Digestion and the absorption of nutrients into the bloodstream are as effortless as breathing and normally produce no sensations such as pain. Most discomfort in the gastrointestinal tract occurs in the two main storage areas: the stomach and the colon. When you feel discomfort above the waist, it is often in your esophagus, stomach, or duodenum, all close to the heart. Thus indigestion is often called heartburn. Discomfort below the waist usually means a problem in the colon, such as constipation or diarrhea.

Your Second Brain: The Mind-Gut Connection

Nervous stomach, gut-wrenching, gut reaction—these are all common terms. We understand them on a gut level without really thinking about how these terms came to be. A case of nerves before making a speech could have you running to the bathroom. A shocking piece of news could make someone throw up. Because of this mysterious connection, people were sometimes told that their digestive problems were all in their mind when they could not be diagnosed or treated effectively. The interaction between body and mind was overemphasized in the past. For example, it was once believed that ulcers were caused by stress. Today we know that while bacteria cause most ulcers, some can be caused by nonsteroidal anti-inflammatory drugs or by gut hormone imbalances such as gastrinoma (Zollinger-Ellison Syndrome).
The gut is, in fact, the center of the enteric nervous system. Nerves travel from the brain to the esophagus, stomach, gallbladder, pancreas, small intestine, and colon. This is why the smell or sight of food can stimulate stomach and intestinal contractions. It also can stimulate stomach acid and pancreatic enzyme secretions.
In the same way, when you are stressed and your nerves are on maximum overload, the ones in your digestive system can cause cramps, too much acid secretion, and other problems. Some of us can handle stress with nary a twitch in our enteric nervous system, but others cannot. Some are so sensitive that they become predisposed to conditions that work hand in hand with such stress, such as irritable bowel syndrome (see chapter 10). In 2000 Michael D. Gershon explained much of this fascinating system—neurogastroenterology—in The Second Brain: A Groundbreaking New Understanding of Nervous Disorders of the Stomach and Intestine.
There is a reason for every disorder, whether or not we can find an organic cause. In fact, digestive disorders are always classified as organic or functional. Organic means it comes from a disease state such as a faulty valve between the esophagus and the stomach, which diagnostic tests can find. When something isn’t working properly but we can’t find any structural or organic damage, then it is called a functional disorder. This could be subtle defects in the chemistry of the system, or that the system is not coordinating. These distinctions make diagnosis and treatment more challenging. Organic problems such as an inflamed colon can be treated with medication and change in diet. Drugs may not help with a functional disorder, such as irritable bowel syndrome, but diet or stress reduction may help.

Food Allergy and Food Intolerance

Although some people have an unpleasant or dangerous reaction to certain food, that same food may be harmless to others. Peanuts, for example, can be fatal to some. An allergic reaction to food is mediated by the immune system, and it tends to be quite predictable. Each time you eat the food, your symptoms begin very quickly. Intolerance is not allergy, but the two are often confused. An intolerance means a particular food causes your body distress a few hours after you eat it. Many people get diarrhea, cramps, or flatulence from drinking cow’s milk. They are not allergic to milk, but their body lacks an enzyme needed to digest the milk sugar lactose.

Food Allergy

Allergies are a reaction of the immune system, but they don’t happen on the first exposure to something. It usually shows up on the second or later exposure, once the first contact has sensitized the body to the offending agent. Symptoms of food allergy may include nausea, vomiting, diarrhea, abdominal pain, indigestion, belching, rash, headache, runny nose, hives, asthma, and swelling of the face or throat. True food allergies are rare in adults. In children, however, they are much more common and may be related to the introduction of solid food too soon, before the small intestine has had a chance to mature and produce the needed enzymes. Sometimes the protein in infant formula or cow’s milk can cause a reaction.
Foods likely to cause a true allergic reaction in adults are peanuts, milk, eggs, fish (especially shellfish), and wheat. One food allergy involving gluten, a protein found in wheat, can actually damage the cell lining of the small intestine, resulting in poor absorption of nutrients, greasy stools, weight loss, and diarrhea. This is known as gluten-sensitive enteropathy or sprue, nontropical sprue, or celiac disease (see chapter 6).

Food Intolerance

Milk and milk products such as cheese and ice cream are responsible for the most common food intolerance, which affects 30 million to 50 million Americans and millions more around the world. It’s the inability to digest lactose, the predominant sugar in milk. Some ethnic populations are more vulnerable than others, especially African Americans, Native Americans, and Mexican Americans. It is least common among people of Northern European descent.
Lactose intolerance comes from a shortage of the enzyme lactase, normally produced by the cells lining the small intestine to break down the milk sugar so it can be absorbed into the bloodstream. Although this condition is not fatal, it can cause nausea, cramps, bloating, gas, and diarrhea. The condition is easily diagnosed with a breath test or stool acidity test (see chapter 11) or careful clinical observation. However, these tests are not 100 percent specific, and in 2003 a new lactose intolerance blood test was made available to identify possible genetic variations responsible for lactose intolerance.
This new test will allow doctors to know if there is a genetic basis for lactose intolerance or if their symptoms are related to another disease or disorder, such as celiac disease or inflammatory bowel disease, which have similar symptoms. Improperly diagnosed and unmanaged, these can lead to serious complications. Until now, diagnostic methods used to detect lactose intolerance could not determine the underlying cause, making treatment choices difficult. The highly specific test identifies patients with a certain genetic marker that is associated with lower-than-normal levels of the lactase enzyme.
There is no cure for lactose intolerance, and avoiding milk sugar is the only treatment. There also are many brands of additives in pill form or chewable tablets that can be used if avoidance of milk and milk products is not practical. Some come as drops you can put into the milk.

Fructose Intolerance

Some people suffer from a more serious problem, known as fructose intolerance or fructose malabsorption, which can be fatal. Technically, it is a hereditary lack of a liver enzyme called aldolase B, which is crucial to the metabolism of fructose, a sugar in soft drinks and juices. To be digested, fructose needs to be broken down before it reaches the colon. If it isn’t, it then becomes a high-octane fuel for intestinal bacteria that would otherwise remain docile. This creates hydrogen gas that causes bloating, pain, and loose stools. The undigested fructose collects in the liver and kidneys, and this leads to failure of those organs.
Fructose intolerance occurs more frequently in the United States and northern European countries than anywhere else. One person in every twenty thousand is born with this disorder. When children inherit fructose intolerance from their parents—both parents carry the gene but may not have the condition themselves—it is often hard to diagnose. The baby may become dehydrated, nauseous, and feverish. Loss of appetite and failure to grow are symptoms, and when tremors and seizures occur, they can lead to coma and death.
The condition is diagnosed through urine and blood tests to determine liver and kidney failure. Enzyme studies and a liver biopsy and genetic testing may be called for. The disease can be treated only by completely eliminating fructose and sucrose from the diet. Some people also may need to take medication to lower the level of uric acid in their blood. This will reduce the risk for gout.

Other Reactions to Food

Some people feel pain after eating fatty foods and think they are allergic, but more likely they are suffering from acid reflux or gallstones. Fatty foods tend to relax the lower esophageal sphincter (LES) valve between the stomach and the esophagus, thus creating heartburn. Fatty foods can cause the gallbladder to contract. If gallstones are present, pain results.
Certain foods or their additives and preservatives may cause symptoms that mimic allergies or intolerance but are not. Fermented cheese, pork sausage, canned tuna, and sardines may contain histamine and for some people can cause flushing, headaches, and a drop in blood pressure. Histamine is a chemical the body’s immune system makes in response to an allergic reaction. Phenylethylamine, a chemical found in chocolate, red wine, and aged cheese can cause migraine headaches in some people. Monosodium glutamate (MSG) can make a susceptible person dizzy or short of breath. MSG used to be found in great quantities in Chinese food, but many restaurants no longer use it, or, if they do, they say so on the menu. Sulfites often are added to salads and vegetables to preserve a fresh appearance and can cause an asthmatic reaction in some people. Yellow food dye number 5, or tartrazine, found in snacks and drinks, can cause hives, asthma, and a runny nose. Nitrates found in smoked meats and cheese can cause gastrointestinal upset, headache, and hives. Some of these substances affect blood vessels directly, giving rise to flushing, headache, and dizziness.

Lifestyle, Aging, and the Gastrointestinal System

More than twenty thousand pounds of solid foods will be digested by the gastrointestinal tract during your lifetime, so it is a very efficient and hardworking system. The fact that people tend to have problems with their digestive system during or after middle age indicates that it may be affected by wear and tear. Polyps may develop in the colon. Inflammation may develop in the esophagus or the stomach. Valves weaken and ducts get clogged. Think of what happens to your car if it runs for years and many miles without a tune-up. The fuel lines get clogged, sludge forms in the engine, and it doesn’t run as efficiently. The digestive system, too, is an energy-driven machine that won’t function as well without care.
The digestive system is at our mercy. Some people are born with stronger “constitutions” than others. However, just as the heart is hurt by bad habits such as smoking, a sedentary lifestyle, and poor nutrition, so is the digestive system harmed. And the harm is cumulative as we age.
Everything we eat, drink, or even inhale affects the dynamics of the digestive system. Not only do we get heartburn, bloating, or indigestion, we also can get ulcers, gallstones, constipation, colon polyps—or cancer. Many of these conditions are caused by eating or drinking the wrong foods and liquids, by not exercising enough, and by not understanding how to prevent problems with early intervention or screening.
One of the biggest problems today (no pun intended) is the increasing size of people in the Western world. The numbers of overweight and obese people has caused the American Gastroenterological Association to urge its member physicians to do more about it. Although obesity is not often identified as a gastrointestinal problem, it can certainly lead to problems. The Association is suggesting approaches ranging from portion control to medications, counseling, and group therapy. Doctors believe there would be fewer cases of reflux disease and other digestive complications if people were thinner. Excess abdominal weight puts more pressure on the valve between the esophagus and the stomach, causing acid to back up. Fat accumulations inside the body, especially around the intestines and lining of the abdomen, put pressure on the valve.
When fat cells accumulate in the liver it can cause steatohepatitis (see chapter 9), a condition that leads to dysfunction of the liver. Obesity is strongly associated with gallstones, adult-onset diabetes, and cancer, including cancer of the colon and rectum. Fat will increase the cholesterol in your blood. This not only increases the risk for heart attack and several cancers, but also before it even gets to your blood, it may cause problems. The gallbladder has to process all the fats you eat, and if you overwork that organ, you may develop gallstones.
Fiber in the form of cereals, whole grains, and fresh fruits and vegetables helps flush the fats and waste products from the body with more efficiency. When there is no fiber to transport the waste matter through the colon and out of the body, it stays in the colon where it may contribute to the growth of polyps. These polyps, if undiscovered, can become cancerous. A tendency to constipation may be hereditary, but constipation, more common in women, is frequently felt to be caused by lack of fiber as well as by a sedentary lifestyle. Exercise is critical to bring oxygen to your digestive system and keep the process going, especially through the lower intestinal tract.
Smoking increases your risk of acid reflux disease and esophageal cancer, stomach cancer, and ulcers. These conditions are especially high among smokers, as are cancers of the entire upper digestive tract. You may think the smoke is going only to your lungs, but it is contaminating the upper part of your digestive tract as well—including your mouth.
Drinking too much alcohol is especially harmful. Alcohol is toxic to the stomach lining and other organs, including the liver, where cirrhosis ultimately begins. Excess alcohol is directly responsible for cancer of the esophagus, bleeding of the stomach lining, ulcers, and destruction of the pancreas and liver.
By the time cancer of a digestive organ causes symptoms, it is frequently advanced. Tumors in the system are usually slow-growing, solid tumors and may not be discovered until they have spread outside the digestive tract and caused problems elsewhere.

Systemic Disease Can Cause Digestive Problems

As a review of the contents of any gastroenterology textbook will attest, more than half of the commonly encountered digestive problems are the result of the effect of systemic diseases on the gastrointestinal tract. Here are just a few:
• Atherosclerosis may cause loss of blood (ischemia) to the intestinal tract.
• Abnormally low blood pressure (hypotension) may “shock” the liver and cause hepatitis, from disruption of blood flow and oxygen supply to the liver.
• Diabetes mellitus may cause fatty liver (hepatic steatosis).
• Scleroderma may affect the function of the esophagus and small intestine.
• Stroke may cause difficulty swallowing.
• Toxic amounts of calcium (hypercalcemia) may result in severe constipation.
It is crucial for you and your doctor to recognize and anticipate that some of these conditions will affect your digestive system. Sometimes gastrointestinal symptoms show up before the actual disease, which makes this awareness even more important.

Common Gastrointestinal Symptoms and Problems

The digestive system is complex, and symptoms of many disorders can be similar. Everyone exhibits occasional symptoms, such as gaseousness or nausea, which usually are transitory. However, when these common symptoms become chronic and can’t easily be explained, it’s time to see your gastroenterologist. Symptoms can be confused with other diseases, too. A spasm in the esophagus can feel just like a heart attack, and to some people it can feel like asthma.
Symptoms that persist or recur should be brought to the attention of your doctor. If you have any of these symptoms, keep a written diary noting any associations with meals, activity, or time of day.

Difficulty Swallowing (Dysphagia)

When it is difficult to swallow solid food and even liquids, you may have esophageal motility problems or an esophageal obstruction. The esophagus can develop problems with the automatic muscular contractions called peristalsis (see pages 72-73). An obstruction, such as a large piece of meat, is called the steakhouse syndrome (see chapter 4). When swallowing is painful, it may indicate inflammation or infection in the esophagus.

Gaseousness and Bloating

Everyone has occasional gas and bloating. Some belching and flatulence is normal. Certain foods produce more gas than others. Gaseousness also is common in people who overeat and in those who are overweight. This can be reduced by eating slowly and chewing food well. If you eliminate chewing gum, smoking, drinking carbonated beverages, and gulping water and other drinks too quickly, you can cut down on the amount of air taken into your digestive system—and thus the amount of air that has to come out one way or another.
Gaseousness and bloating are very nonspecific symptoms and take on meaning only in association with other symptoms.

Noncardiac Chest Pain

Heartburn, indigestion, esophageal spasm, or a gallbladder attack can seem just like a heart attack. This kind of symptom should never be ignored. Your doctor will know how to tell the difference, but sometimes the similarity is so great that tests must be done to rule out a cardiac problem. Any significant chest pain or discomfort (including meal-related) should be considered cardiac until proven otherwise.

Nausea and Vomiting

Many digestive conditions can cause nausea and vomiting, such as a stomach virus, liver disease, or hepatitis. Acute pancreatitis can cause nausea along with knife-like pain in the upper abdomen. Pregnant women often become nauseated in the mornings during their first trimester, but we don’t really know why. It may be caused by hormonal changes or lower blood sugar during that period. However, conditions that don’t originate in the digestive system, such as dehydration, loss of equilibrium, and vertigo, can cause nausea.

Abdominal Pain

Abdominal pain is a common symptom for a wide variety of gastrointestinal conditions as well as other diseases, such as an ovarian cyst in women. Much abdominal pain can be identified by its location. Pain on the lower left side can be irritable bowel syndrome, diverticulitis, or some other chronic or gynecological problem. On the lower right it could be appendicitis, an ovarian cyst, or Crohn’s disease. Pain in the upper abdomen could be caused by the gallbladder, pancreatitis, stomach ulcers, or liver disease. The character of the pain (described to the experienced ears of a physician) can further help define what is going on.

Unexplained Weight Loss

If you are losing weight without trying, it is possible that you have a maldigestion or malabsorption problem. This means your food is not being digested properly and nutrients are not absorbed into the bloodstream. Malabsorption can be a sign of celiac disease. However, this type of weight loss could be a symptom of several other very serious diseases and should never go unreported to your doctor.

Constipation

People can become constipated because of their diet or because they don’t drink enough water and get enough exercise. Certain medications also can cause constipation. In addition, it can be caused by blockage in the intestines, or by a class of irritable bowel syndrome. When constipation lasts more than a week it’s a good idea to see your doctor. Over-the-counter remedies should be used only occasionally unless you are under the supervision of your doctor.

Diarrhea

Diarrhea can be a temporary result of a stomach virus, food poisoning, or use of certain medications. Many more serious conditions have this symptom, including a class of irritable bowel syndrome, inflammatory bowel disease, Crohn’s disease, colon polyps, and celiac disease. If it lasts more than thirty-six hours,call your doctor.

Rectal Bleeding

Blood on the surface of the stool is often caused by hemorrhoids or an anal fissure. Hidden blood in the stool can be a symptom of colon polyps, a tumor, or inflammatory bowel disease. Because you may be unaware of hidden blood, you should discuss with your doctor whether you need a yearly fecal occult blood test (see chapter 2). Never ignore this symptom.

Jaundice

Yellowing of the skin and whites of the eyes is an indication of a liver problem. It could be hepatitis, a blocked bile duct, or cancer of the liver or biliary tree. Jaundice calls for immediate medical attention.

Abdominal Swelling

There is a difference between abdominal bloating and swelling. Bloating is caused by gas and usually is temporary. Swelling can be caused by a collection of fluid in the abdominal space. This is known as ascites and often is a symptom of liver disease. The doctor can feel the water sloshing around on physical exertion.
There are, of course, many other symptoms of digestive diseases, but these are the most common. In the next two chapters you will learn when and how to find a gastroenterologist and what kinds of diagnostic tests (including an entire chapter on endoscopic tests) are available to diagnose symptoms.
Chapter 2
How to Find a Gastroenterologist and the Proper Diagnosis
MEDICINE IS AN EVER-CHANGING science, and this certainly applies to gastroenterology. As a patient you want to have access to the best and latest that modern medicine has to offer. Often this will mean seeing a well-trained gastroenterologist who is board-certified, participates in continuing medical education, and is on the staff of a university teaching hospital or a large suburban hospital.
By finding such a person, it is likely that he or she also will be affiliated with radiologists, surgeons, pathologists, and others who are similarly trained and credentialed. As the field of gastroenterology has evolved, many changes have taken place. Endoscopy has largely replaced barium X-ray studies of the gut. CT, MRI, and sonography have become mainstays of diagnosis of gastrointestinal problems. Endoscopic ultrasound and ERCP (endoscopic retrograde cholangiopancreatography) have become important tools used to diagnose biliary and pancreatic disorders. (Chapter 3 explains endoscopic tests and therapy in detail.)
Capsule camera studies now allow more precise visualization of the small intestine. CT colonography—or virtual colonoscopy—is fast becoming an alternate for conventional endoscopy. New diagnostic blood tests are developed every year. New medications appear monthly. Techniques such as laparoscopic surgery and robotic surgery are becoming the norm. Hospital stays are shortening, and more and more testing and care are being rendered in an outpatient setting. Unfortunately, much of this is being done or developed seemingly at the expense of the doctor-patient-family relationship. We must never lose sight of the dictum “For the secret of the care of the patient is in caring for the patient.” Francis W. Peabody said this to Harvard students in 1925 in a landmark lecture titled “The Care of the Patient.” His book of the same title is still used in medical schools today.
Most primary care physicians are internists or family practitioners who can treat simple gastrointestinal problems such as indigestion. However, you may need to see a gastroenterologist for persistent discomfort, pain, acid reflux, diarrhea, or constipation. Your primary care physician is not trained to perform endoscopic testing or to interpret many of the newer tests.
A gastroenterologist is an internist who specializes in diagnosis and treatment of diseases of the digestive system and has been trained in endoscopic diagnostic and treatment procedures. In addition to four years of medical school, training includes three to eight years of graduate medical education in the specialty and on-the-job hospital training. The doctor must pass licensing examinations to become accredited.
There are other specialists who treat digestive diseases. A colorectal surgeon has special training in treatment of diseases of the colon, including the rectum and anus. A hepatologist is an internist who limits his or her practice to diseases of the liver, and often has advanced training in gastroenterology as well. An oncologist is an internist who specializes in the treatment of cancer. A radiologist does not evaluate gastrointestinal problems but may be asked to perform diagnostic tests.
A trusting relationship between doctor and patient is essential. Ask other doctors you know for their recommendations. Your primary care physician will be able to recommend one or more gastroenterologists, but it is a good idea to do some research on your own to find a doctor you feel comfortable with. Also talk with patients who have experience with gastroenterologists about how effective their treatment was, and what they liked or disliked about the treatment or the doctor. Many people go from one doctor to another until they find someone who can help them. You should not be reluctant to “doctor-shop” to find the best care possible. Often, people insured with HMOs look in their health care directory and hope for the best. Some are unaware that they can challenge the system and become well-informed patients. If you call your health insurance provider and ask where you can find a doctor who specializes in gastroenterology, they will ask you, “What’s your zip code?” They assume that nobody wants to go far from home to find a doctor. Consult more knowledgeable sources such as doctors you know and professional medical associations such as your state medical society; books such as this one; the Internet; and other patients. Ask them what hospitals and doctors have the best reputations for treating your condition.
Your state medical society and the American Medical Association have physician referral services to help you locate a specialist. Go to www.ama-assn.org and click on the AMA Physician Select. Another popular physician listing site is CastleConnolly.com, which has a “Find a Doctor” link. This is a bit like the Zagat ratings of restaurants. Physician profiles are selected after peer nomination, extensive research, and careful review and screening by their own physician-directed research team.
Most states have a department of education that will provide records of the doctor’s licensing. To find out if a specialist is accredited, check with the American Board of Medical Specialties. Then you can check with your state department of health to find out if the doctor was subject of any disciplinary action. All of these organizations can be contacted through the Internet. (Keep in mind that there is a great deal of erroneous information on the Internet. For that reason, we’ve listed some reputable information sources in the back of the book.)
Once your primary care physician learns that you are willing to go to great lengths to get the best care, he or she may help you interpret some of the information you gather. Choose doctors who have not only a great deal of compassion but also up-to-date knowledge and experience and who are able to treat you with the best medical care possible. Once you’ve found some doctors you believe might be able to help you, talk to them or their office staff before you decide. Many doctors or their office managers will talk with you as a potential patient on the phone for a few minutes if you make an appointment to do this. Be sure to ask about hospital affiliations, hours, availability, and health insurance.

About Diagnostic Testing

There are scores of diagnostic tests for tracking down the cause of digestive diseases. Some, such as breath tests, are easy to do and noninvasive. They can be done by a doctor in the office. Endoscopic tests, on the other hand, require more time and expense. With some, sedatives or anesthesia is needed. They usually involve a technician as well as the doctor, and sometimes more than one doctor (see chapter 3). In another category, scans such as CT or MRI, and the new virtual colonoscopy, require that you go to a medical center or hospital.
Because symptoms are similar for a variety of gastroenterological conditions, most diagnoses must be made through a process of excluding all possibilities. Before any diagnostic tests are performed, a physical examination as well as a detailed history of symptoms and lifestyle are needed.
Since the 1970s it has become much easier to look inside the digestive system to find out what exactly is wrong. Endoscopic procedures usually are more expensive than regular X-rays, but they are the most effective. In the past (and still today) barium enemas were given as an X-ray examination to look inside the colon. Colonoscopy is much more efficient, but as we will see later, there are certain instances where a barium enema X-ray is still recommended. Such tests should be done only by a qualified and experienced physician, and they should be done where there is access to the most up-to-date equipment.

Noninvasive Tests

Breath tests, stool tests, blood tests, and simple X-rays can be used to find out if the problem can be solved quickly or if more testing is needed to pinpoint diagnosis.

Breath Tests

A breath test is a simple, quick, and safe way to investigate several digestive diseases before doing more invasive tests. Both the hydrogen breath tests and the new 13C stable radioisotope breath tests are nonradioactive and safe for anyone, including children and pregnant women. Breath tests can help identify Helicobacter pylori infection, bacterial overgrowth, bile salt waste, lactose and fructose intolerance, and pancreatic insufficiency.
Normally there is no hydrogen in the breath. But let’s say you are lactose-intolerant. Undigested lactose forms gases, including hydrogen, in the colon. The hydrogen is absorbed from the intestines and carried through the bloodstream to the lungs and exhaled. To take the test you drink a lactose-loaded beverage, and then your exhaled breath is analyzed at regular intervals.
In another example, the H. pylori bacteria in the stomach can convert a naturally occurring substance called urea into carbon dioxide, ammonia, and water. If you swallow a special solution and then exhale, the test can identify that. A tiny amount of non radioactive-labeled urea is put into a glass of orange juice that you drink. Half an hour later, you blow into a small test tube. If H. pylori is present in the stomach, it will digest the urea and release a small amount of the tracer with the breath. This safe and easy test is more accurate than a blood test. It can detect active infection, whereas the blood test can tell only if you had been exposed to H. pylori at some time in life and developed antibodies. Breath tests also are very useful in checking on whether an infection has been successfully treated.
Fasting is required the night before this test, and you need to talk with your doctor about medications you need to stop taking ahead of time. Accuracy of the breath test is reduced if you have been taking certain drugs, such as antibiotics, during the previous weeks.

Blood Tests

Several blood tests can be used to track various digestive diseases. A complete blood count (CBC) tests for anemia, which can result from blood loss from the gut. In addition, blood tests can be targeted at liver enzymes, bilirubin and bile salt levels, hepatitis, pancreatitis, malabsorption, and inflammation. Some are designed to monitor treatment with medications, identify people with inflammatory blood disease, help differentiate Crohn’s disease from ulcerative colitis, identify liver fibrosis in people with hepatitis C, identify gluten sensitivity, and find out if certain medications would be toxic to some people.

Stool Acidity Test

The stool acidity test is often used to measure the amount of acid in the stool of infants and young children to determine if they are lactose-intolerant. Undigested lactose is fermented by bacteria in the colon and creates lactic acid and fatty acids that can be found in stool samples. Glucose also may be present in the sample because it is not being absorbed by the colon.

Fecal Occult Blood Test

The loss of blood that is hidden in the stool can indicate ulcers or polyps and is the most common sign of cancer of the colon and rectum. The fecal occult blood test, first introduced to clinical practice in the 1950s, has come to be regarded as a valuable aid in colorectal and gastrointestinal cancer surveillance.
The fecal occult blood test (FOBT) is a simple test using a card on which samples of stool can be smeared and analyzed. The currently available guaiac-impregnated cards are very accurate when used properly. These cards are most often given to patients by their physicians, but FOBT cards are often available at hospital and health fairs (such as those in communities or malls), and from nurses or health offices in the workplace. And, like the home pregnancy test, the FOBT also is available over the counter in some drugstores.
The collection of two smears per day from different parts of the stool for three days is recommended. A chemical is applied to the samples at the doctor’s office or at a laboratory, or a person can do it at home. If the sample turns blue, it indicates the presence of blood in the stool.
Before testing for hidden blood, patients often are asked to follow a special diet for two days because the digestion of certain foods can cause a false positive or false negative result. (Patients do not always comply with these dietary restrictions, and some do not supply the number of samples required.) For example, fiber is allowed because it is believed to stimulate bleeding from any existing polyps protruding into the colon passageway. On the other hand, aspirin is to be avoided because it can cause bleeding that has nothing to do with a possible polyp in the colon, and it could cause a false positive result.
Other foods and substances to avoid for that reason include red meat, turnips, horseradish, citrus fruits and vitamin C, and iron supplements. Patients are asked to eat high-fiber foods such as bran, peanuts, and popcorn, as well as fruits and vegetables, chicken, and tuna fish.

Absorption Tests

Several tests can be used to find out why the digestive system is not properly absorbing nutrients from food.

D-Xylose Absorption Test

Lower-than-normal amounts of D-xylose in the blood and urine samples may suggest that the small intestine is not absorbing nutrients from food properly. This could be caused by Crohn’s disease, sprue, or celiac disease. It also may indicate inflammation in the lining of the small intestine from an infection or from a parasite, such as giardiasis or hookworm.
For this test, a drink containing sugar is swallowed, and later urine and blood are tested for levels of D-xylose, a type of sugar normally absorbed by the intestine but not used in the body. This is a test to determine if the intestine is absorbing nutrients properly. If it is not, the amounts of D-xylose in the blood and urine will be low.
Before the test there must be abstinence from foods and liquids high in pentose, a sugar similar to D-xylose. These include fruits, jams, and pastries. Some medications also may interfere with the test, so your doctor may stop these temporarily before the test. Urine is checked before the test and then after drinking a solution with D-xylose. Then blood samples are collected within two hours of taking the solution and again five hours later. All of the urine produced over the five-hour period also will be collected and tested. Sometimes this urine collection is extended for twenty-four hours.

Schilling Test for B12Absorption

Deficiency of vitamin B12 is often an indication of anemia, gastric atrophy, bacterial overgrowth, or disease of the ileum. This test can identify the deficiency.

Serum Carotene Levels

Carotene is a fat-soluble substance found in yellow vegetables and fruits as well as in eggs. Serum carotene levels tend to be depressed in patients who don’t absorb fats. However, they also can be depressed if intake of dietary carotene is low.

Stool Test for Fecal Fat

When too much fat is detected in stool, it means it is not being absorbed properly in the digestive system. This could be due to failure of the bile system, severe liver disease, or bacterial overgrowth in the small intestine. The test can evaluate how fats are digested by determining if there is excessive excretion of lipids in people who show signs of malabsorption such as weight loss, abdominal distention, and scaly skin.
Stool must be collected over a seventy-two-hour period while the patient maintains a high-fat diet. Alcohol and certain drugs must be withheld during this time because they can affect the results.

Electrogastrogram

An electrogastrogram (EGG) is like an electrocardiogram (EKG) of the heart. It records electrical signals that travel through the muscles of the stomach and control the reaction of those muscles. The EGG is used to confirm a doctor’s suspicion that the stomach muscles or the nerves controlling them are not working normally.
Electrodes are taped over the abdomen, and the sounds are recorded on a computer. The test, which takes about three hours, usually is done after fasting and then again after eating. Normally there is a regular rhythm generated by the stomach muscles, just like there is in the heart. The power—electrical voltage—increases after a meal. When there are abnormalities in those muscles or nerves, the rhythm is often irregular, or there is no increase after eating.
There is no other test like this one, but antroduodenal motility studies or gastric emptying studies may provide additional information. Abnormal electrical activity of the stomach sometimes results in abnormal muscular activity and reduced emptying of food from the stomach.
The EGG is still considered an experimental procedure, and its exact role in diagnosis of stomach disease is not yet defined.

Abdominal Sonography

Abdominal ultrasound is used to image the liver, gallbladder, spleen, pancreas, and kidneys. The blood vessels of these organs also can be evaluated. Ultrasound sends out high-frequency sound waves that reflect off body structures to create a picture. There is no radiation exposure with this test. This also can be done endoscopically (see chapter 3). Ultrasound sometimes is used to supplement endoscopy to determine if a lesion is solid. The physician or a technician scans your abdomen by a handheld transducer or probe that converts the sound waves that bounce off your body into images on a screen.

Radiological Tests

When simple tests are not conclusive, then X-rays and other radiological tests such CT scans are needed to see images inside the body.

Barium X-rays, Upper GI Series

Also called barium swallows and upper GI series, this is done when endoscopy cannot be used, when there is difficulty swallowing, or ulcer symptoms, heartburn, or occult gastrointestinal bleeding. It can help diagnose narrowing of the esophagus, inflammation or strictures of the esophagus, hiatal hernia, spasms, and gastric and duodenal ulcers or tumors.
Barium is a radiopaque liquid that shows up white in X-rays. After you swallow it, a radiologist uses a fluoroscope connected to a TV monitor to observe the progress of barium through your digestive tract. The radiologist takes a series of X-rays of the esophagus, stomach, and the first part of the small intestine (duodenum). If Crohn’s disease is suspected, a similar test will be performed immediately afterward to examine the entire length—more than twenty feet—of the small intestine. Sometimes the procedure uses “double contrast” media. This means you also swallow tablets to release gas in your stomach. The gas helps to show the stomach lining in greater detail.

Barium Enema X-ray

This X-ray procedure sometimes is used in conjunction with sigmoidoscopy to provide complementary information, especially if an obstruction is detected in the colon. The barium enema X-ray is still a time-honored tool for finding polyps, but not all physicians find it necessary. Most believe that if a polyp is found with sigmoidoscopy, then the patient should proceed to the more accurate colonoscopy to examine the entire length of the colon and should have the polyp removed and a biopsy done at the same time. However, some health insurance companies and health maintenance organizations might require the barium enema X-ray as part of the screening procedure for colon cancer because it is generally less expensive than colonoscopy.
After the colon is cleansed with enemas, an inert substance containing barium is inserted into the rectum and colon through the anus. Barium appears opaque on X-rays. The camera watches under fluoroscopic guidance and X-ray pictures as the barium fills the colon and rectum. To make small tumors easier to see, the doctor also might expand the colon by carefully pumping in air during the test. This is called an air contrast or double contrast barium enema and improves the accuracy of the standard barium enema X-ray.
A technician generally performs a large part of the procedure in conjunction with a physician (radiologist). The physician will look at the films as they are developed and possibly again later. The sensitivity of this screening procedure is directly related to the patience and diligence of the technician and physician performing the procedure. Overlapping loops of bowel can be difficult to interpret, and extensive diverticulosis or residual fecal material also can interfere with an accurate reading. There is normally a small risk associated with radiation exposure, but the real limitation in this procedure is that a biopsy or polypectomy cannot be performed if a polyp is discovered. The test takes about an hour.
After the test you’ll need to drink plenty of fluids and rest. The procedure can be tiring. Also, you may need to take another enema to rid the colon of any remaining barium. You may have pale-colored stools for the next day or two.

Abdominal X-ray

An abdominal X-ray is helpful in ruling out free air within the abdominal cavity; this air shows up just under the diaphragm and if present could indicate a ruptured bowel or appendix. The air pattern within the intestinal tract is useful in diagnosis. Usually air is seen in the loops of the large intestine. When air is prominent in the small intestine or the stomach, intestinal obstruction is likely. Occasionally a kidney stone, gallstone, or pancreatic calcification can be visualized on X-ray.
Be sure to inform your doctor if you are pregnant or have an IUD inserted, or if you have had a barium-contrast X-ray in the previous four days. Also, if you have taken medications such as Pepto-Bismol (which contains bismuth) within four days, let the doctor know because it could interfere with the test.

Oral Cholecystogram

This is a test to get images of the gallbladder and is performed in a hospital radiology department or freestanding radiology facility. The night before the test, you are asked to swallow some pills that contain the contrast medium that allows visualization of the gallbladder during the X-ray. Then you can eat a fat-free meal. However, once the tablets have been ingested, you cannot drink any liquid. The doctor uses a fluoroscope, a special X-ray that projects images onto a video monitor. You may be asked to assume various positions. Additionally, you may be asked to drink a high-fat formula that will force the gallbladder to contract and release some bile.

Computerized Tomographic Scan

A computerized tomographic (CT) scan is an excellent way to look at the abdominal wall and the lymph-node-bearing areas of the abdomen, liver, and other solid organs for signs of cancer metastasis. While you lie inside a wide tube, this X-ray translates information into two-dimensional “slices,” or cross sections. The radiation dose from a CT scan is considerably higher than from a routine X-ray. The amount depends on the number of slices needed and on the part of the body. A CT scan also is used in planning radiation treatment to outline the field or area to be treated. A CT scan offers the best initial evaluation of the pancreas and is 85 percent specific in chronic pancreatitis. CT provides good visualization of the entire liver and pancreas to spot any complications. It also is used for diagnosing diverticulitis. A CT scan can be done to the entire body or particular areas.
If your doctor has asked for a contrast-enhanced CT scan, you will be injected with a contrast agent and X-rays will be taken. It is important to remain very still during the scanning so the X-rays will not be blurred. CT scans are a hundred times more sensitive than regular X-rays and can allow the radiologist to see minute differences in soft tissue within the body.
Helical or spiral CT of the abdomen and pelvis requires fasting for four to six hours if contrast dye is to be used or sedation is anticipated.

CT Colonography (Virtual Colonoscopy)

Virtual colonoscopy is an examination of the colon without an invasive tube. It combines X-rays and computers to view inside the entire colon without inserting anything but air. This is a relatively new form of X-ray technology called spiral CT. The exam takes ten to twenty minutes and requires no sedation. It is less expensive than conventional colonoscopy.